Special Issue "Systems Medicine and Bioinformatics"

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Omics/Informatics".

Deadline for manuscript submissions: 20 November 2021.

Special Issue Editors

Dr. Ali Salehzadeh-Yazdi
Guest Editor
Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, 18057 Rostock, Germany.
Interests: systems medicine; omics data integration; regulation of gene expression; metabolic modeling; protein–protein interaction; signaling pathways analysis; drug repurposing; bioinformatics and computational biology
Dr. Mohieddin Jafari
Guest Editor
Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Interests: proteomics; systems biology; mass spectrometry; bioinformatics; biological data mining; omics data integration; machine learning methods; network biology; network pharmacology

Special Issue Information

Dear Colleagues,

In precision medicine, determining the right treatment for the right patients based on a precise diagnosis is the ultimate goal. It guides us to provide considerable progress to our knowledge of disease etiology and pathogenesis and have a determinant impact on proposing novel potential biomarkers suitable for clinical practice.

To achieve this goal, molecular features and clinical phenotypes are used to perform the correct stratification of patients and classify the corresponding features. Recent advances in sequencing and multi-omics technologies transform biomedical research and change healthcare and medicine by providing big data as molecular and clinical features. In parallel, advanced statistical, computational, and mathematical tools to analyze, integrate, interpret big heterogeneous datasets, and develop multilevel models are demanded.

We encourage the submission of original and review articles to this Special Issue of the Journal of Personalized Medicine that cover the "Systems medicine and bioinformatics". Articles focused on empirical and computational studies, implementation of new models along with the validations, focusing on the barriers to expanding systems medicine into personalized and precision medicine will be welcome.

Dr. Ali Salehzadeh-Yazdi
Dr. Mohieddin Jafari
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • systems medicine
  • high-throughput datasets analysis (genomic, epigenomic, functional genomic, etc.)
  • omics data integration
  • human disease network
  • network pharmacology
  • drug repurposing (drug repositioning)
  • machine learning methods
  • computational models and algorithms
  • phenotypes prediction
  • drug target prediction
  • signaling pathways analysis

Published Papers

This special issue is now open for submission.
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