Advances in Gynecological Cancers: Targeted Diagnosis, Treatment, and Personalized Care for Ovarian, Cervical, and Endometrial Tumors

Dear Colleagues,
Gynecological cancers—ovarian, endometrial, and cervical—continue to present significant clinical challenges, but the last decade has seen transformative progress in both diagnosis and treatment. From a uniform approach, we are moving toward increasingly personalized care, supported by advances in imaging, molecular profiling, and targeted therapies. This Special Issue aims to explore how these innovations are reshaping clinical pathways in gynecologic oncology, from early detection to therapeutic decision-making and surgical strategy. In ovarian cancer, the improved understanding of platinum resistance is guiding the development of new treatment approaches. In endometrial cancer, long considered under-prioritized, molecular classification has revolutionized risk stratification and is challenging traditional staging and treatment algorithms. For cervical cancer, the role of minimally invasive surgery and the concept of surgical radicality are being re-evaluated in light of new evidence. Across all tumor types, ultrasound is gaining ground as a real-time, accessible imaging tool with diagnostic and potentially predictive value. For this Special Issue, we invite original articles, reviews, and clinical studies focused on diagnostic innovation, molecular characterization, therapeutic resistance, targeted treatments, surgical strategies, and the integration of personalized care in ovarian, endometrial, and cervical cancers.

Dr. Elisa Scarpelli

Guest Editor

Dr. Elisa Scarpelli
Dr. Vito Andrea Capozzi
Guest Editors

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