Journal of Personalized Medicine

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Special Issue Editors

Special Issue Information

Dear Colleagues,

[*] Background & history of this topic: General surgery has seen a constant evolution over time in correlation with the other branches of medicine. The appearance of new interventional techniques, the impact of technological development, and the appearance of sub-specializations in general surgery require a reorganization and updating of knowledge in the field.

[*] Aim and scope of the Special Issue: The aim of this Special Issue is to publish cutting-edge clinical and translational scientific research and technologies related to general surgery and its related fields viewed from the perspective of personalized medicine (e.g., precision surgery, surgical anatomy, new surgical techniques, and general surgery patient management).

The scope of this Special Issue is to publish original research but also reviews about new surgical procedures; advances and major trends that shape general surgery in oncology; trauma, gastrointestinal, vascular, and transplant surgery; and post-interventional recovery in the context of personalized medicine.

[*] Cutting-edge research: Robotic surgery remains at the top of the cutting-edge technology list in general surgery. At the same time, new discoveries continue to emerge in the field of surgery performed through the natural openings of the human body, minimally invasive endocrine surgery, emergency surgery, radiology, and surgical anatomy due to the complexity of surgical patient management.

[*] What kind of papers we are soliciting: This Special Issue will accept submissions of original manuscripts, as well as review or letter to the editor manuscripts on general surgery and its related fields, such as postoperative intensive care, pre- and postoperative medical imaging, and surgical anatomy. These articles must be designed from the point of view of the individual characteristics of the patients, the existence of some risk groups of surgical patients, and the need to customize interventional and post-interventional follow-up protocols in certain situations.

Dr. Marius Valeriu Hînganu
Dr. Delia Hînganu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

personalized surgery
cutting-edge general surgery
individualized surgical protocols
future of general surgery

Published Papers (2 papers)

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Review

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16 pages, 283 KiB

Open AccessReview

Thymus Surgery Prospectives and Perspectives in Myasthenia Gravis

by Paul Salahoru, Cristina Grigorescu, Marius Valeriu Hinganu, Tiberiu Lunguleac, Alina Ioana Halip and Delia Hinganu

J. Pers. Med. 2024, 14(3), 241; https://doi.org/10.3390/jpm14030241 - 23 Feb 2024

Viewed by 779

Abstract

The thymus is a lymphoid organ involved in the differentiation of T cells, and has a central role in the physiopathogenesis of Myasthenia Gravis (MG). This connection is proved by a series of changes in the level of neuromuscular junctions, which leads to a decrease in the amplitude of the action potential in the post-synaptic membrane. Because of this, the presence of anti-cholinergic receptor antibodies (AChR), characteristic of MG, is found, which causes the progressive regression of the effect of acetylcholine at the level of neuromuscular junctions, with the appearance of muscle weakness. The thymectomy is a surgical variant of drug therapy administered to patients with MG. In the case of patients with nonthymomatous MG, thymectomy has become a therapeutic standard, despite the fact that there is no solid scientific evidence to explain its positive effect. Videothoracoscopic surgery or robotic surgery led to a decrease in the length of hospital stay for these patients. This paper aims to synthesize the information presented in the literature in order to create a background for the perspectives of thymectomy. Full article

(This article belongs to the Special Issue General Surgery: Current Position and Future Directions Applied to Personalized Medicine)

Other

Jump to: Review

13 pages, 3656 KiB

Open AccessCase Report

Experience in the Application of Augmented Reality Technology in the Surgical Treatment of Patients Suffering Primary and Recurrent Pelvic Tumors

by Vladimir M. Ivanov, Anton M. Krivtsov, Anton Yu. Smirnov, Vladimir G. Grebenkov, Dmitry A. Surov, Michail S. Korzhuk, Sergey V. Strelkov and Elena G. Ivanova

J. Pers. Med. 2024, 14(1), 19; https://doi.org/10.3390/jpm14010019 - 22 Dec 2023

Viewed by 737

Abstract

Surgical treatment of locally spread tumors in pelvic organs remains an urgent and complicated oncological problem. The recurrence rate after radical treatment ranges from 15.1% to 45.2%. The key to successful and safe surgical intervention lies in meticulous planning and intraoperative navigation, including the utilization of augmented reality (AR) technology. This paper presents the experience of clinically testing an AR technology application algorithm in the surgical treatment of 11 patients. The main stages of the algorithm are described. Radical operations incorporating intraoperative AR technology with favorable outcomes were performed on eight patients. One patient underwent a palliative intervention, while two patients did not undergo surgery. The testing of the algorithm for the application of AR technology in the surgical treatment of primary and recurrent pelvic tumors demonstrated both a technical possibility and reproducibility of this algorithm and the AR technology itself in clinical practice. Full article

(This article belongs to the Special Issue General Surgery: Current Position and Future Directions Applied to Personalized Medicine)

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