Antifungal Drugs 2022

Dear Colleagues,

Compared to many kinds of antibiotics for bacteria, antifungal drugs used for treating fungal infections in clinics and hospitals are limited. Antifungal drugs such as azoles, echinocandins, and polyenes are currently used for the treatment of invasive fungal infections caused by pathogens entering the human bloodstream, central nervous system, and organs such as liver and lungs, sometimes leading to life-threatening diseases to immunocompromised and immunosuppressed individuals. However, some of these antifungals are known to participate in drug–drug interactions and cause serious side effects. In addition, the antifungal and multidrug resistances of opportunistic fungi, including Aspergillus fumigatus, Candida albicans, and Cryptococcus neoformans, have increased and become a significant burden in clinical sites in the world. Recently, emerging fungal species such as C. auris were isolated, and some of their strains also show antifungal and multi-drug resistances.

The aim of this Special Issue is to highlight current research and the development of novel antifungal drugs and drug resistances in invasive fungal infection to humans.

Prof. Dr. Susumu Kajiwara
Guest Editor

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