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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition
edited by
submission deadline 31 Jul 2026 | 2 articles | Viewed by 1761 | Submission Open
Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry
(This special issue belongs to the Section Mental Health)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Aug 2026 | 3 articles | Viewed by 4264 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools
(This special issue belongs to the Section Mental Health)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3946 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
Current Trends and Progress in Eating Disorders and Obesity Management
edited by Davide Gravina, and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 736 | Submission Open
Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics
(This special issue belongs to the Section Mental Health)
Precision Neuroimaging in Mental and Behavioral Health Research
edited by Thomas Vanicek and Arkadiusz Komorowski
submission deadline 20 Aug 2026 | Viewed by 345 | Submission Open
Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics
(This special issue belongs to the Section Mental Health)
Novel Approaches in Obsessive–Compulsive and Related Spectrum Disorders
edited by and Andrea D. Guastello
submission deadline 20 Aug 2026 | Viewed by 288 | Submission Open
Keywords: OCD; misophonia; hoarding; tic disorders; assessment; treatment
(This special issue belongs to the Section Mental Health)
New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles
edited by , Serdar Dursun and
submission deadline 10 Sep 2026 | 5 articles | Viewed by 17327 | Submission Open
Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD
(This special issue belongs to the Section Mental Health)
Postpartum Depression: What Happened to My Wife? submission deadline 20 Sep 2026 | 3 articles | Viewed by 3153 | Submission Open
Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life
(This special issue belongs to the Section Mental Health)
Current Challenges and Approaches to Post-Traumatic Stress Disorder (PTSD)
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 1951 | Submission Open
Keywords: PTSD treatment; implementation; prevention; prevalence; risk factors
(This special issue belongs to the Section Mental Health)
Clinical Advances in Autism Management submission deadline 20 Sep 2026 | 1 articles | Viewed by 1691 | Submission Open
Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization
(This special issue belongs to the Section Mental Health)
Perinatal and Postnatal Mental Health: State of the Art
edited by Adriana Mihai
submission deadline 20 Sep 2026 | 1 articles | Viewed by 977 | Submission Open
Keywords: peripartum depression; post-partum depression; parental–infant well-being; early detection; perinatal mental health; postnatal mental health; psychotherapy interventions
(This special issue belongs to the Section Mental Health)
Obsessive–Compulsive Disorder (OCD): Understanding, Treatment, and New Directions in Psychotherapy
edited by Franziska Sophia Miegel
submission deadline 20 Sep 2026 | Viewed by 367 | Submission Open
Keywords: obsessive–compulsive disorder; clinical psychopathology; mechanisms of change; psychotherapeutic interventions; treatment delivery; accessibility of care; innovative treatment approaches; technology-supported interventions
(This special issue belongs to the Section Mental Health)
Emerging Therapeutic Interventions for Eating Disorders Through Psychology
edited by Anita Federici and
submission deadline 20 Sep 2026 | Viewed by 216 | Submission Open
Keywords: eating disorders; psychological interventions; emerging psychotherapies; dialectical behavior therapy (DBT); transdiagnostic approaches; emotion regulation; severe and enduring eating disorders; treatment development and adaptation; implementation and feasibility; integrated medical–psychological care
(This special issue belongs to the Section Mental Health)
Advances in Schizophrenia and Related Psychotic Disorders
edited by Giovanni Camardese and Michele Ribolsi
submission deadline 25 Sep 2026 | 4 articles | Viewed by 4786 | Submission Open
Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics
(This special issue belongs to the Section Mental Health)
Burnout and Anxiety in Clinical and Occupational Contexts: Mental Health, Work-Related Stress, and Vulnerable Populations submission deadline 30 Sep 2026 | 1 articles | Viewed by 807 | Submission Open
Keywords: mental health; burnout; anxiety; occupational stress; women’s mental health; perinatal mental health; healthcare professionals; work-related stress; psychosocial factors; clinical interventions
(This special issue belongs to the Section Mental Health)
Eating Disorders and Psychological Disorders: Current Challenges and New Perspectives submission deadline 20 Oct 2026 | 1 articles | Viewed by 988 | Submission Open
Keywords: eating disorders; psychological comorbidities; psychological disorders; psychological factors; multidimensional investigation; person-centered approach; subjective experience
(This special issue belongs to the Section Mental Health)
Personalized Medicine in Psychiatry: Precision Approaches to Diagnosis and Treatment
edited by Simran Maggo
submission deadline 20 Oct 2026 | Viewed by 243 | Submission Open
Keywords: pharmacogenomics; precision medicine; precision psychiatry; pharmacogenomic testing; pharmacogenomic bioinfor-matics
(This special issue belongs to the Section Mental Health)
New Insights in Diagnosis, Symptomatology, and Therapy in Schizophrenia and Schizoaffective Disorders
edited by Felix-Martin Werner and Arturo Mangas
submission deadline 31 Oct 2026 | Viewed by 248 | Submission Open
Keywords: schizophrenia; schizoaffective disorder; paranoia; acoustic hallucinations; positive schizophrenia symptoms; negative schizophrenia symptoms; second-generation antipsychotic drugs; risperidone; clozapine; cariprazine; xanomeline combined with trospium
(This special issue belongs to the Section Mental Health)
New Clinical Advances in Depressive Disorders and Treatment-Resistant Depression
edited by Giacomo d'Andrea and
submission deadline 10 Nov 2026 | 3 articles | Viewed by 4113 | Submission Open
Keywords: treatment-resistant depression; MDD; ketamine; esketamine; rTMS; psylocibin; bipolar depression; clinical pheno-typing; precision psychiatry; biomarkers
(This special issue belongs to the Section Mental Health)
Clinical Interventions for Cognitive Impairment and Neurological Disorders submission deadline 15 Nov 2026 | 1 articles | Viewed by 613 | Submission Open
Keywords: exercise; mental disorders; mental health; physical function; depression; anxiety; cognitive function; lifespan; physical activity
(This special issue belongs to the Section Mental Health)
Innovations in the Treatment for Depression and Anxiety—2nd Edition
edited by
submission deadline 20 Nov 2026 | 4 articles | Viewed by 1598 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Digital Mental Health and Artificial Intelligence: Clinical Perspectives and Patient Safety
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1162 | Submission Open
Keywords: mental health care; telepsychiatry; telepsychotherapy; patient safety; health care data; clinical practice; digital mental health interventions; artificial intelligence in psychiatry; digital trust human–robot interactions; social networks
(This special issue belongs to the Section Mental Health)
Attention-Deficit/Hyperactivity Disorder, Psychiatric Comorbidity and Substance Use Disorders: Clinical Complexity Across the Lifespan
edited by Miriam Olivola and Paola Landi
submission deadline 20 Nov 2026 | 1 articles | Viewed by 564 | Submission Open
Keywords: ADHD; psychiatric comorbidity; substance use disorder; emotional dysregulation; impulsivity; dual diagnosis; adult ADHD; addiction vulnerability; neurodevelopmental disorders; transdiagnostic psychopathology
(This special issue belongs to the Section Mental Health)
Psychological Safety: Bodily and Psychological Determinants in Clinical Settings
edited by and Stephen W. Porges
submission deadline 20 Nov 2026 | 1 articles | Viewed by 554 | Submission Open
Keywords: psychological safety; fear; psychological trauma; shame; dissociation; neuroception; trust; polyvagal theory
(This special issue belongs to the Section Mental Health)
Clinical Advances in Psychotic Disorders: Precision Diagnosis and Personalized Treatment
edited by
submission deadline 20 Nov 2026 | Viewed by 235 | Submission Open
Keywords: psychotic disorders; early detection; precision diagnosis; personalized interventions; functional recovery; personal recovery; cognitive remediation; psychosocial treatment; recovery-oriented care; individualized care plans; digital mental health; telepsychiatry; artificial intelligence; virtual reality; predictive modeling
(This special issue belongs to the Section Mental Health)
Clinical Advances in Personalized Psychiatry
edited by
submission deadline 25 Nov 2026 | 3 articles | Viewed by 2195 | Submission Open
Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments
(This special issue belongs to the Section Mental Health)
Self-Injurious Thoughts and Behaviors: Risk, Mechanisms, and Clinical Intervention
edited by
submission deadline 15 Dec 2026 | Viewed by 179 | Submission Open
Keywords: self-injurious thoughts and behaviors; suicide; suicidal ideation; suicide attempts; non-suicidal self-injury; NSSI; self-harm; emotion dysregulation; trauma; risk factors; resilience; prevention; clinical intervention; adolescents; young adults
(This special issue belongs to the Section Mental Health)
Integrating Mental Health Into Chronic Illness Care: Interdisciplinary Clinical Strategies
edited by Emanuele Maria Merlo
submission deadline 15 Dec 2026 | Viewed by 175 | Submission Open
Keywords: clinical psychology; psychosomatic medicine; assessment; chronic illness; mental health; patient-centred care
(This special issue belongs to the Section Mental Health)
Pharmacotherapy of Mental Diseases: Latest Developments submission deadline 20 Dec 2026 | 2 articles | Viewed by 1612 | Submission Open
Keywords: brain stimulation; mental health; novel intervention; pharmacotherapy; psychotherapy; quality of life; psychologi-cal well-being; treatment personalization in mental diseases
(This special issue belongs to the Section Mental Health)
Schizophrenia and Psychotic Disorders: Clinical Updates submission deadline 20 Dec 2026 | 1 articles | Viewed by 919 | Submission Open
Keywords: schizophrenia spectrum disorder; mobile health apps; antipsychotics; repetitive transcranial magnetic stimulation; artificial intelligence; machine learning; augmented reality; neuroimaging; treatment resistance; quality of life; comorbidities
(This special issue belongs to the Section Mental Health)
Transdiagnostic Insights to Eating Disorders: Bridging Cognitive Processes and Clinical Outcomes
edited by and Patrizia Todisco
submission deadline 20 Dec 2026 | Viewed by 198 | Submission Open
Keywords: eating disorders; cognitive processes; emotional regulation; social cognition; neurocognitive functioning; interoception; body representation; clinical outcomes; psychopathology
(This special issue belongs to the Section Mental Health)
Vulnerability and Resilience in the Perinatal Period: Focus on Maternal and Paternal Mental Health
edited by
submission deadline 20 Dec 2026 | Viewed by 169 | Submission Open
Keywords: perinatal mental health; maternal mental health; paternal mental health; resilience; perinatal wellbeing; dyadic processes; parent–infant relationship; perinatal affective disorders; perinatal psychiatry
(This special issue belongs to the Section Mental Health)
Advancing Autism Care: Early Diagnosis and Care Pathways for Autistic Children
edited by Laura Maria Fatta
submission deadline 20 Dec 2026 | Viewed by 167 | Submission Open
Keywords: early diagnosis; developmental outcomes; integrated care pathways; real-world clinical care; care coordination; evidence-based interventions; family support systems
(This special issue belongs to the Section Mental Health)
How Clinicians See the Use of AI in Psychiatry
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1352 | Submission Open
Keywords: artificial intelligence; psychiatry; patient care; psychotherapy
(This special issue belongs to the Section Mental Health)
Clinical Management of Attention Deficit Hyperactivity Disorder (ADHD) submission deadline 15 Jan 2027 | 4 articles | Viewed by 10722 | Submission Open
Keywords: ADHD; addiction; neurodevelopmental disorders; levomethadone
(This special issue belongs to the Section Mental Health)
Effect of Long-Term Insomnia on Mental Health—2nd Edition submission deadline 20 Jan 2027 | 2 articles | Viewed by 13211 | Submission Open
Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress
(This special issue belongs to the Section Mental Health)
Advances in Perinatal Mental Health: Prevention, Screening, Treatment, and Support Across Pregnancy and Postpartum
edited by
submission deadline 20 Jan 2027 | 1 articles | Viewed by 376 | Submission Open
Keywords: perinatal mental health; prevention; screening; access to care; eHealth; treatment; environmental factors; cross-cultural; systems of care; innovative methodologies
(This special issue belongs to the Section Mental Health)
Mind–Body Connection: The Impact of Mental Health on Physical Well-Being
edited by
submission deadline 30 Jan 2027 | 5 articles | Viewed by 10272 | Submission Open
Keywords: mind–body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare
(This special issue belongs to the Section Mental Health)
Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults
edited by
submission deadline 15 Feb 2027 | 1 articles | Viewed by 3207 | Submission Open
Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care
(This special issue belongs to the Section Mental Health)
Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition
edited by Andrea Fagiolini
submission deadline 20 Feb 2027 | 2 articles | Viewed by 1544 | Submission Open
Keywords: obsessions–compulsions; anxiety; OCD symptoms; treatment options; functional impairment
(This special issue belongs to the Section Mental Health)
Towards a Better Understanding of Neuroinflammation in Mental Health
edited by Jesus Cobo
submission deadline 20 Feb 2027 | Viewed by 269 | Submission Open
Keywords: neuroinflammation; biomarkers; peripheral biomarkers; outcomes; bipolar disorders; major depression; mental health; schizophrenia; blood-based inflammatory index; lymphocyte subpopulation
(This special issue belongs to the Section Mental Health)
Alcohol Use Disorder: New Clinical Insights and Management Strategies
edited by Daniel König
submission deadline 20 Feb 2027 | Viewed by 125 | Submission Open
Keywords: alcohol use disorder; emerging treatments; comorbidities; outcomes; epidemiology; dual-diagnosis; interventions
(This special issue belongs to the Section Mental Health)
Clinical Advances and New Perspectives in the Diagnosis and Treatment of Schizophrenia
edited by Pierre S. Chue and Oloruntoba J. Oluboka
submission deadline 22 Feb 2027 | 1 articles | Viewed by 819 | Submission Open
Keywords: psychopharmacology; schizophrenia; long-acting injectable therapy; recovery; team approach to care; integrated care; clozapine; habilitation; rehabilitation; early intervention
(This special issue belongs to the Section Mental Health)
The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications
edited by and
submission deadline 25 Feb 2027 | Viewed by 374 | Submission Open
Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications
(This special issue belongs to the Section Mental Health)
Clinical Diagnosis and Management of Attention-Deficit/Hyperactivity Disorder (ADHD) submission deadline 10 Mar 2027 | Viewed by 65 | Submission Open
Keywords: ADHD; randomized controlled trials; clinical research; neurodevelopmental disorders; cognitive function; prefrontal cortex; diagnostic methods; therapeutic interventions; evidence-based medicine
(This special issue belongs to the Section Mental Health)
Clinical Advances and Emerging Trends in Neuropsychology submission deadline 15 Mar 2027 | Viewed by 118 | Submission Open
Keywords: neuropsychology; affective neuroscience; social neuroscience; brain–behavior relationship; emotional processing; emotion regulation; memory; personalized mental health; therapeutic factors
(This special issue belongs to the Section Mental Health)
Current Therapeutic Approaches to Addictive Disorders
edited by Linda Haddad
submission deadline 20 Mar 2027 | 1 articles | Viewed by 910 | Submission Open
Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support
(This special issue belongs to the Section Mental Health)
Advances in Mental Health: All Ages and Multidisciplinary Clinical Perspectives
edited by Clara González-Sanguino and
submission deadline 20 Mar 2027 | Viewed by 157 | Submission Open
Keywords: stigma; discrimination; mental health; clinical psychology; depression and anxiety
(This special issue belongs to the Section Mental Health)
Psychosis Across Disciplines: Emerging Perspectives in Neuroscience, Psychiatry, and Therapy
edited by Inmaculada Peñuelas-Calvo, Roberto Rodríguez-Jiménez and
submission deadline 20 Mar 2027 | Viewed by 114 | Submission Open
Keywords: psychosis; lifespan; neuroimaging; psychotherapy; prevention
(This special issue belongs to the Section Mental Health)
Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach submission deadline 24 Mar 2027 | 4 articles | Viewed by 2090 | Submission Open
Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care
(This special issue belongs to the Section Mental Health)
From Psychological Distress to Well-Being: Prevention and Interventions Across Clinical and Applied Settings
edited by Dominika Wilczyńska
submission deadline 25 May 2027 | Viewed by 116 | Submission Open
Keywords: psychological well-being; mental health; psychological distress; depression; high-functioning depression; burnout; resilience; physical activity; exercise interventions; positive psychology
(This special issue belongs to the Section Mental Health)
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