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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Substance and Behavioral Addictions: Prevention and Diagnosis

edited by

Icro Maremmani

submission deadline 20 Dec 2025 | 7 articles | Viewed by 18164 | Submission Open

Keywords: substance addiction; behavioural addiction; clinical perspectives; prevention strategies; diagnostic protocols; differential diagnosis; psychopathology of addiction; psychopathology as a diagnostic tool; craving behavioural covariates

(This special issue belongs to the Section Mental Health)

Psychological Pain and Suicidal Behavior: Clinical Implications

edited by Adrián Alacreu-Crespo

submission deadline 25 Dec 2025 | Viewed by 290 | Submission Open

Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes

(This special issue belongs to the Section Mental Health)

Emerging Clinical Insights into Adolescent Behavioral Development and Mental Health

edited by

Ainzara Favini

and Anne-Marie Iselin

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2190 | Submission Open

Keywords: adolescence; behavioral development; clinical maladjustment; adolescents’ mental health; innovative clinical approach; adolescents’ emotional problems; clinical settings; innovative developmental research; adolescents’ symptoms

(This special issue belongs to the Section Mental Health)

Children and Adolescent Mood Disorders: Risks and Treatment

edited by

Angelo Fraschetti

and

Emanuela Mari

submission deadline 31 Dec 2025 | Viewed by 1530 | Submission Open

Keywords: emotional dysregulation; mood disorders; adolescence; anxiety; depression; addiction; psychotherapy; pharmacological treatments; prevention programs

(This special issue belongs to the Section Mental Health)

Innovations in Psychosis and Schizophrenia: New Findings and Implications

edited by

Gabriele Nibbio

submission deadline 31 Dec 2025 | 1 articles | Viewed by 813 | Submission Open

Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions

(This special issue belongs to the Section Mental Health)

Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment

edited by

Camilla Gesi

submission deadline 5 Jan 2026 | 1 articles | Viewed by 2855 | Submission Open

Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted

(This special issue belongs to the Section Mental Health)

Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care

edited by

Benedetta Muzii

Nelson Mauro Maldonato

and

Andrea Bovero

submission deadline 20 Jan 2026 | 3 articles | Viewed by 6533 | Submission Open

Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors

(This special issue belongs to the Section Mental Health)

Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition

edited by

Arthur Eumann Mesas

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5161 | Submission Open

Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention

(This special issue belongs to the Section Mental Health)

From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding

edited by

Angelo Giovanni Icro Maremmani

submission deadline 20 Jan 2026 | Viewed by 211 | Submission Open

Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models

(This special issue belongs to the Section Mental Health)

Autism Spectrum Disorder: Diagnosis, Treatment, and Management

edited by

Marios Adamou

submission deadline 25 Jan 2026 | 1 articles | Viewed by 3878 | Submission Open

Keywords: adult autism (including autism spectrum disorders); neurodevelopmental disorders; clinical diagnostics; digital diagnostics; artificial intelligence; multimodal treatments

(This special issue belongs to the Section Mental Health)

Clinical Outcomes in Bipolar and Depressive Disorders

edited by

Luca J. Steardo

and Francesco Monaco

submission deadline 30 Jan 2026 | 1 articles | Viewed by 782 | Submission Open

Keywords: mood disorders; clinical outcomes; treatment response; psychopathology; pathophysiology

(This special issue belongs to the Section Mental Health)

Mind–Body Connection: The Impact of Mental Health on Physical Well-Being

edited by

Mario Pinto

submission deadline 30 Jan 2026 | 1 articles | Viewed by 605 | Submission Open

Keywords: mind– body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare

(This special issue belongs to the Section Mental Health)

Advancements and Future Directions in Clinical Psychosis

edited by

Marco Colizzi

and

Alessandra Martinelli

submission deadline 10 Feb 2026 | 1 articles | Viewed by 1005 | Submission Open

Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools

(This special issue belongs to the Section Mental Health)

Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights

edited by Scott G. Ravyts and Margot De Kooning

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1783 | Submission Open

Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma

(This special issue belongs to the Section Mental Health)

Progress and Innovation in the Clinical Management of Psychosis

edited by

Valerio Ricci

submission deadline 20 Feb 2026 | Viewed by 162 | Submission Open

Keywords: psychosis; schizophrenia; clinical interventions; neurobiological mechanisms; early intervention

(This special issue belongs to the Section Mental Health)

Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update

edited by An-Fu Hsiao and

Michael Hollifield

submission deadline 20 Feb 2026 | Viewed by 126 | Submission Open

Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology

(This special issue belongs to the Section Mental Health)

(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition

edited by

Pietro Muratori

and

Valentina Levantini

submission deadline 25 Feb 2026 | 5 articles | Viewed by 10674 | Submission Open

Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders

(This special issue belongs to the Section Mental Health)

Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders

edited by

Argyro Pachi

Ioannis Ilias

and

Athanassios Tselebis

submission deadline 10 Mar 2026 | 5 articles | Viewed by 14602 | Submission Open

Keywords: sleep; circadian rhythms; insomnia; depression; physical health; mental health; circadian medicine; chronotype; chronotherapy; melatonin

(This special issue belongs to the Section Mental Health)

Innovations in the Treatment for Depression and Anxiety

edited by Lucie Bartova

submission deadline 20 Mar 2026 | 3 articles | Viewed by 8278 | Submission Open

Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance

(This special issue belongs to the Section Mental Health)

Clinical Therapy in Dementia and Related Diseases

edited by

Takao Yamasaki

submission deadline 20 Mar 2026 | 3 articles | Viewed by 2592 | Submission Open

Keywords: dementia; aging society; disease-modifying therapies (DMT); early diagnosis; lifestyle interventions; multimorbidity management; non-pharmacological treatments; personalized medicine; quality of life (QOL); digital health technologies

(This special issue belongs to the Section Mental Health)

Clinical Advances in Autism Management

edited by

Justyna Podgórska-Bednarz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 632 | Submission Open

Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization

(This special issue belongs to the Section Mental Health)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

, Ana Filipa Beato and

Stephanie Alves

submission deadline 20 Mar 2026 | Viewed by 170 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles

edited by

Massimo Tusconi

, Serdar Dursun and

Germano Orru

submission deadline 25 Mar 2026 | 4 articles | Viewed by 11959 | Submission Open

Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD

(This special issue belongs to the Section Mental Health)

Advances in Stigma and Discrimination in Pediatric Mental Health

edited by

Clara González-Sanguino

and

Jairo Rodríguez-Medina

submission deadline 25 Mar 2026 | 4 articles | Viewed by 9945 | Submission Open

Keywords: stigma; discrimination; childhood; mental health; clinical psychology

(This special issue belongs to the Section Mental Health)

Attention-Deficit–Hyperactivity Disorder (ADHD): Bridging Theory and Clinical Application

edited by Rafał R. Jaeschke

submission deadline 25 Mar 2026 | 3 articles | Viewed by 5941 | Submission Open

Keywords: ADHD; emotional dysregulation; diagnosis and assessment; pharmacological and non-pharmacological treatments; neurobiology; comorbidities

(This special issue belongs to the Section Mental Health)

Advances in Schizophrenia and Related Psychotic Disorders

edited by Giovanni Camardese and Michele Ribolsi

submission deadline 25 Mar 2026 | Viewed by 114 | Submission Open

Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics

(This special issue belongs to the Section Mental Health)

Clinical Practice Guidelines for the Treatment and Management of Peripartum Depression, 2nd Edition

edited by

Silvia Cimino

submission deadline 15 Apr 2026 | 2 articles | Viewed by 9116 | Submission Open

Keywords: peripartum depression; early detection; clinical health psychology; psychotherapy interventions; parental– infant well-being

(This special issue belongs to the Section Mental Health)

Treatment Personalization in Clinical Psychology and Psychotherapy

edited by

Dariusz Krok

submission deadline 20 Apr 2026 | 14 articles | Viewed by 36395 | Submission Open

Keywords: treatment personalization; clinical psychology; psychotherapy; personalized treatment; psychosomatic interventions; coping and personalization

(This special issue belongs to the Section Mental Health)

Schizophrenia and Psychotic Disorders: Clinical Updates

edited by

Octavian Vasiliu

and

Adela Magdalena Ciobanu

submission deadline 20 Apr 2026 | Viewed by 106 | Submission Open

Keywords: schizophrenia spectrum disorder; mobile health apps; antipsychotics; repetitive transcranial magnetic stimulation; artificial intelligence; machine learning; augmented reality; neuroimaging; treatment resistance; quality of life; comorbidities

(This special issue belongs to the Section Mental Health)

Pharmacotherapy of Mental Diseases: Latest Developments

edited by

Lavinia Maria Hogea

and

Laura Alexandra Nussbaum

submission deadline 20 Apr 2026 | Viewed by 105 | Submission Open

Keywords: brain stimulation; mental health; novel intervention; pharmacotherapy; psychotherapy; quality of life; psychologi-cal well-being; treatment personalization in mental diseases

(This special issue belongs to the Section Mental Health)

New Clinical Advances in Depressive Disorders and Treatment-Resistant Depression

edited by Giacomo d'Andrea and

Miriam Olivola

submission deadline 30 Apr 2026 | Viewed by 144 | Submission Open

Keywords: treatment-resistant depression; MDD; ketamine; esketamine; rTMS; psylocibin; bipolar depression; clinical pheno-typing; precision psychiatry; biomarkers

(This special issue belongs to the Section Mental Health)

Clinical Management of Attention Deficit Hyperactivity Disorder (ADHD)

edited by

Alessandro Pallucchini

submission deadline 15 May 2026 | Viewed by 319 | Submission Open

Keywords: ADHD; addiction; neurodevelopmental disorders; levomethadone

(This special issue belongs to the Section Mental Health)

Effect of Long-Term Insomnia on Mental Health—2nd Edition

edited by

Aleksandra Rogowska

submission deadline 20 May 2026 | 1 articles | Viewed by 7765 | Submission Open

Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress

(This special issue belongs to the Section Mental Health)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 20 May 2026 | Viewed by 42 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 22 May 2026 | 4 articles | Viewed by 10155 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

The Association Between Sleep Disorders and Metabolic and Mental Health

edited by

Filip Franciszek Karuga

Piotr Bialasiewicz

and

Marcin Sochal

submission deadline 25 May 2026 | 5 articles | Viewed by 11777 | Submission Open

Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health

(This special issue belongs to the Section Mental Health)

Clinical Advances in Personalized Psychiatry

edited by

Rosaria Di Lorenzo

submission deadline 25 May 2026 | Viewed by 77 | Submission Open

Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments

(This special issue belongs to the Section Mental Health)

How Clinicians See the Use of AI in Psychiatry

edited by

Georgios Floros

submission deadline 25 May 2026 | Viewed by 57 | Submission Open

Keywords: artificial intelligence; psychiatry; patient care; psychotherapy

(This special issue belongs to the Section Mental Health)

Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition

edited by Andrea Fagiolini

submission deadline 20 Jun 2026 | Viewed by 62 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

Towards a Better Understanding of Neuroinflammation in Mental Health

edited by Jesus Cobo

submission deadline 20 Jun 2026 | Viewed by 31 | Submission Open

Keywords: neuroinflammation; biomarkers; peripheral biomarkers; outcomes; bipolar disorders; major depression; mental health; schizophrenia; blood-based inflammatory index; lymphocyte subpopulation

(This special issue belongs to the Section Mental Health)

Clinical Advances and New Perspectives in the Diagnosis and Treatment of Schizophrenia

edited by Pierre S. Chue and Oloruntoba J. Oluboka

submission deadline 22 Jun 2026 | Viewed by 37 | Submission Open

Keywords: psychopharmacology; schizophrenia; long-acting injectable therapy; recovery; team approach to care; integrated care; clozapine; habilitation; rehabilitation; early intervention

(This special issue belongs to the Section Mental Health)

Clinical Insights and Challenges into Cognitive and Mental Health in Older Adults

edited by Dariusz Krok

submission deadline 23 Jun 2026 | Viewed by 59 | Submission Open

Keywords: clinical insights; cognitive and mental health; older adults; psychosomatic interventions; person-centered care

(This special issue belongs to the Section Mental Health)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Jul 2026 | Viewed by 15 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

Psychological Affliction in Pregnancy, Delivery and Postpartum Period: A Multidisciplinary Approach

edited by

Beata Pięta

and

Edyta Barnas̈

submission deadline 24 Jul 2026 | Viewed by 87 | Submission Open

Keywords: maternal mental health; pregnancy; postpartum depression; perinatal anxiety; midwifery; multidisciplinary care

(This special issue belongs to the Section Mental Health)

Psychogerontology: Psychological Insights into Aging

edited by Sónia Martins and

Sara Lima

submission deadline 31 Jul 2026 | Viewed by 433 | Submission Open

Keywords: psychogerontology; aging process; adjustment; mental health; psychopatology; personality; emotions; well-being; spir-ituality; quality of life; caregiving; psychogerontology assessment and interventions

(This special issue belongs to the Section Mental Health)

Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition

edited by

Georgios Floros

submission deadline 31 Jul 2026 | Viewed by 23 | Submission Open

Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry

(This special issue belongs to the Section Mental Health)

Precision Neuroimaging in Mental and Behavioral Health Research

edited by Thomas Vanicek and Arkadiusz Komorowski

submission deadline 20 Aug 2026 | Viewed by 9 | Submission Open

Keywords: psychiatry; neuroimaging; addiction; substance use disorders (SUD); attention deficit hyperactivity disorder (ADHD); imaging genomics; imaging transcriptomics

(This special issue belongs to the Section Mental Health)

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