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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Stress, Rhythms Dysregulation and Bipolar Spectrum submission deadline 20 Jul 2025 | 15 articles | Viewed by 25361 | Submission Open
Keywords: bipolar spectrum; neo-Kraepelinian tradition; dimensional approach; social rhythms; chronobiological rhythms
(This special issue belongs to the Section Mental Health)
Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care submission deadline 30 Jul 2025 | 2 articles | Viewed by 2569 | Submission Open
Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors
(This special issue belongs to the Section Mental Health)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Aug 2025 | Viewed by 179 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition submission deadline 25 Aug 2025 | 3 articles | Viewed by 4483 | Submission Open
Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders
(This special issue belongs to the Section Mental Health)
Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders submission deadline 12 Sep 2025 | 3 articles | Viewed by 5328 | Submission Open
Keywords: sleep; circadian rhythms; insomnia; depression; physical health; mental health; circadian medicine; chronotype; chronotherapy; melatonin
(This special issue belongs to the Section Mental Health)
Obsessive Compulsive Disorder: Clinical Advances and Future Perspectives
edited by Andrea Fagiolini
submission deadline 20 Sep 2025 | 4 articles | Viewed by 6290 | Submission Open
Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment
(This special issue belongs to the Section Mental Health)
Advances in Stigma and Discrimination in Pediatric Mental Health submission deadline 20 Sep 2025 | 3 articles | Viewed by 3608 | Submission Open
Keywords: stigma; discrimination; childhood; mental health; clinical psychology
(This special issue belongs to the Section Mental Health)
Clinical Therapy in Dementia and Related Diseases
edited by
submission deadline 25 Sep 2025 | Viewed by 171 | Submission Open
Keywords: dementia; aging society; disease-modifying therapies (DMT); early diagnosis; lifestyle interventions; multimorbidity management; non-pharmacological treatments; personalized medicine; quality of life (QOL); digital health technologies
(This special issue belongs to the Section Mental Health)
Attention-Deficit–Hyperactivity Disorder (ADHD): Bridging Theory and Clinical Application
edited by Rafał R. Jaeschke
submission deadline 25 Sep 2025 | Viewed by 132 | Submission Open
Keywords: ADHD; emotional dysregulation; diagnosis and assessment; pharmacological and non-pharmacological treatments; neurobiology; comorbidities
(This special issue belongs to the Section Mental Health)
Innovations in the Treatment for Depression and Anxiety
edited by Lucie Bartova
submission deadline 30 Sep 2025 | 1 articles | Viewed by 962 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Targeted Diagnosis and Treatment of Maladaptive Developmental Trajectories and Psychopathological Manifestations in Children and Adolescents
edited by , Andrea Baroncelli and Valeria Giostra
submission deadline 1 Oct 2025 | 1 articles | Viewed by 731 | Submission Open
Keywords: maladaptive developmental trajectories; developmental psychopathology; predictors and correlates of distress in children and adolescents; new forms of social-emotional difficulties and distress; clinical and social interventions and preventions; cognitive; affective; expressive and social improvement of children and adolescents; conduct problems; evidence-based practices; early interventions
(This special issue belongs to the Section Mental Health)
Clinical Practice Guidelines for the Treatment and Management of Peripartum Depression, 2nd Edition
edited by
submission deadline 10 Oct 2025 | 1 articles | Viewed by 2615 | Submission Open
Keywords: peripartum depression; early detection; clinical health psychology; psychotherapy interventions; parental– infant well-being
(This special issue belongs to the Section Mental Health)
Psychogerontology: Psychological Insights into Aging
edited by Sónia Martins and
submission deadline 17 Oct 2025 | Viewed by 183 | Submission Open
Keywords: psychogerontology; aging process; adjustment; mental health; psychopatology; personality; emotions; well-being; spir-ituality; quality of life; caregiving; psychogerontology assessment and interventions
(This special issue belongs to the Section Mental Health)
Mood Disorders: Diagnosis, Management and Future Opportunities
edited by
submission deadline 20 Oct 2025 | 12 articles | Viewed by 19696 | Submission Open
Keywords: mood disorders; depression; anxiety; stress; trauma; suicide; mental health diagnosis and treatment
(This special issue belongs to the Section Mental Health)
Treatment Personalization in Clinical Psychology and Psychotherapy
edited by
submission deadline 20 Oct 2025 | 7 articles | Viewed by 11660 | Submission Open
Keywords: treatment personalization; clinical psychology; psychotherapy; personalized treatment; psychosomatic interventions; coping and personalization
(This special issue belongs to the Section Mental Health)
Management in Autism Spectrum Disorder: From Biomarkers to Precision Medicine submission deadline 25 Oct 2025 | 2 articles | Viewed by 1716 | Submission Open
Keywords: autism; autism spectrum disorder; neurodevelopmental disorders; epigenetics of autism; genetic inheritance; immunogenetics
(This special issue belongs to the Section Mental Health)
New Update on Personalized Treatment of Autism Spectrum Disorder and Related Disorders
edited by , Rosamaria Siracusano and Erica Pironti
submission deadline 30 Oct 2025 | 2 articles | Viewed by 4653 | Submission Open
Keywords: autism spectrum disorder; autism related disorders; children and adolescents; intervention strategies; therapeutic advance; new technologies; evidence-based practices
(This special issue belongs to the Section Mental Health)
Potential Cures of Alzheimer's Dementia
edited by
submission deadline 10 Nov 2025 | 4 articles | Viewed by 13081 | Submission Open
Keywords: Alzheimer’ s dementia; cure; therapeutic approaches; clinical assessment; diagnosis; treatment
(This special issue belongs to the Section Mental Health)
Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment
edited by
submission deadline 10 Nov 2025 | 3 articles | Viewed by 6443 | Submission Open
Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry
(This special issue belongs to the Section Mental Health)
The Association Between Sleep Disorders and Metabolic and Mental Health submission deadline 20 Nov 2025 | 3 articles | Viewed by 3807 | Submission Open
Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health
(This special issue belongs to the Section Mental Health)
Effect of Long-Term Insomnia on Mental Health—2nd Edition submission deadline 21 Nov 2025 | 1 articles | Viewed by 125 | Submission Open
Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress
(This special issue belongs to the Section Mental Health)
Clinical Features and Management of Psychosis
edited by , George Konstantakopoulos and Michael Hadjulis
submission deadline 23 Nov 2025 | Viewed by 382 | Submission Open
Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis
(This special issue belongs to the Section Mental Health)
Perinatal Mental Health Management submission deadline 25 Nov 2025 | 3 articles | Viewed by 6102 | Submission Open
Keywords: perinatal mental health; child mental health; problem behavior; cognitive development therapy; hyperactivity
(This special issue belongs to the Section Mental Health)
Substance and Behavioral Addictions: Prevention and Diagnosis
edited by
submission deadline 20 Dec 2025 | 3 articles | Viewed by 4720 | Submission Open
Keywords: substance addiction; behavioural addiction; clinical perspectives; prevention strategies; diagnostic protocols; differential diagnosis; psychopathology of addiction; psychopathology as a diagnostic tool; craving behavioural covariates
(This special issue belongs to the Section Mental Health)
Psychological Pain and Suicidal Behavior: Clinical Implications
edited by Adrián Alacreu-Crespo
submission deadline 25 Dec 2025 | Viewed by 97 | Submission Open
Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes
(This special issue belongs to the Section Mental Health)
Children and Adolescent Mood Disorders: Risks and Treatment submission deadline 31 Dec 2025 | Viewed by 1344 | Submission Open
Keywords: emotional dysregulation; mood disorders; adolescence; anxiety; depression; addiction; psychotherapy; pharmacological treatments; prevention programs
(This special issue belongs to the Section Mental Health)
Innovations in Psychosis and Schizophrenia: New Findings and Implications
edited by
submission deadline 31 Dec 2025 | Viewed by 84 | Submission Open
Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions
(This special issue belongs to the Section Mental Health)
Emerging Clinical Insights into Adolescent Behavioral Development and Mental Health
edited by and Anne-Marie Iselin
submission deadline 31 Dec 2025 | Viewed by 60 | Submission Open
Keywords: adolescence; behavioral development; clinical maladjustment; adolescents’ mental health; innovative clinical approach; adolescents’ emotional problems; clinical settings; innovative developmental research; adolescents’ symptoms
(This special issue belongs to the Section Mental Health)
Broadening the Knowledge of Autism Spectrum Disorder in Adulthood: Advances in Diagnosis, Assessment and Treatment
edited by
submission deadline 5 Jan 2026 | 1 articles | Viewed by 703 | Submission Open
Keywords: autism spectrum disorder; adulthood; autism; comorbidity; gender; age-adjusted
(This special issue belongs to the Section Mental Health)
Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition submission deadline 20 Jan 2026 | 1 articles | Viewed by 209 | Submission Open
Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention
(This special issue belongs to the Section Mental Health)
From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding submission deadline 20 Jan 2026 | Viewed by 31 | Submission Open
Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models
(This special issue belongs to the Section Mental Health)
Mind–Body Connection: The Impact of Mental Health on Physical Well-Being
edited by
submission deadline 30 Jan 2026 | Viewed by 52 | Submission Open
Keywords: mind– body connection; mental health; well-being; metabolic balance; immune system; chronic medical conditions; body perception; self-image; eating disorders; psychosomatic disorders; psychosomatic medicine; innovative thera-peutic approaches; mindfulness; mind-wandering; integrated healthcare
(This special issue belongs to the Section Mental Health)
Clinical Outcomes in Bipolar and Depressive Disorders
edited by and Francesco Monaco
submission deadline 30 Jan 2026 | Viewed by 45 | Submission Open
Keywords: mood disorders; clinical outcomes; treatment response; psychopathology; pathophysiology
(This special issue belongs to the Section Mental Health)
Advancements and Future Directions in Clinical Psychosis submission deadline 10 Feb 2026 | Viewed by 9 | Submission Open
Keywords: clinical psychosis; schizophrenia spectrum disorders; early detection of psychosis; treatment-resistant psychosis; long-term outcomes; personalized psychiatry; digital mental health; AI in psychiatry; neurocognitive interventions; psychosocial therapies; translational psychiatry; interdisciplinary mental health; psychosis clinical trials; innova-tive diagnostic tools
(This special issue belongs to the Section Mental Health)
Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update
edited by An-Fu Hsiao and
submission deadline 20 Feb 2026 | Viewed by 24 | Submission Open
Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology
(This special issue belongs to the Section Mental Health)
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