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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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One Airway, Many Specialists: Multidisciplinary Innovation in Thoraco-Pulmonary Diseases—Insights from the XXIII SIET National Meeting
edited by Federico Raveglia, and
submission deadline 30 Apr 2027 | Viewed by 155 | Submission Open
Keywords: thoraco-pulmonary diseases; endoscopy; thoracic surgery; airway oncology; pleural diseases; mediastinal disorders; digital medicine; artificial intelligence; anesthesiology; radiology; respiratory; diagnosis, treatment and prognosis
(This special issue belongs to the Section Respiratory Medicine)
Artificial Intelligence (AI) in Dental Clinical Practice
edited by and Keiichiro Watanabe
submission deadline 5 May 2027 | 7 articles | Viewed by 9018 | Submission Open
Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Vascular and Endovascular Surgery: State of the Art and Emerging Insights
edited by Georgios Meimarakis and Volker Ruppert
submission deadline 10 May 2027 | 3 articles | Viewed by 1168 | Submission Open
Keywords: carotid stenosis; peripheral arterial disease; abdominal aortic aneurysm; type B aortic dissection; chronic limb-threatening ischemia; endovascular therapy; vascular surgery; drug-coated balloon; hemodialysis access; health disparities
(This special issue belongs to the Section Vascular Medicine)
Maternal–Fetal Health Monitoring, Prediction and Management of Perinatal Complications
edited by Ioakeim Sapantzoglou and Marianna Theodora
submission deadline 10 May 2027 | Viewed by 88 | Submission Open
Keywords: fetal medicine; prenatal assessment; fetal ultrasound; prenatal genetics; maternal medicine; fetal monitoring; high risk pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Research and Application of Orthopedic Rehabilitation and Ultrasound-Guided Interventional Procedures
edited by Danilo Donati
submission deadline 10 May 2027 | Viewed by 8 | Submission Open
Keywords: orthopaedic rehabilitation; clinical and diagnostical evaluation; clinical physiopathogenesis of muscle; tendon and joint disease; prevention of fall risks; treatment of musculoskeletal disease; ultrasound; interventional procedures; neuropathies
(This special issue belongs to the Section Orthopedics)
Clinical Advances in the Use of Ultrasound in Critical Care
edited by
submission deadline 15 May 2027 | Viewed by 209 | Submission Open
Keywords: ultrasound; intensive care medicine; shock; hemodymanic monitoring; ARDS
(This special issue belongs to the Section Intensive Care)
Artificial Intelligence and Machine Learning in Cardiovascular Disease: Diagnosis, Risk Stratification, and Prognosis
edited by and Aonghus Lawlor
submission deadline 15 May 2027 | Viewed by 135 | Submission Open
Keywords: artificial intelligence; machine learning; cardiovascular disease; diagnosis; risk prediction; prognosis; tripod+ai; external validation; clinical decision support; predictive modeling
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Clinical Intervention in Inflammatory Skin Diseases submission deadline 15 May 2027 | Viewed by 83 | Submission Open
Keywords: inflammatory skin diseases; rosacea; psoriasis; atopic dermatitis; acne; non invasive skin imaging; clinical intervention; laser therapy in dermatology; device-based dermatologic interventions
(This special issue belongs to the Section Dermatology)
Clinical Management in Hand Trauma: Diagnosis, Repair and Rehabilitation submission deadline 19 May 2027 | Viewed by 24 | Submission Open
Keywords: trauma prevention; fractures; nerve injuries; tendon surgery; hand rehabilitation
(This special issue belongs to the Section Orthopedics)
The Role of Cardiovascular Imaging in Pericardial, Myocardial and Vascular Inflammation submission deadline 20 May 2027 | 1 articles | Viewed by 738 | Submission Open
Keywords: inflammatory cardiovascular disease; pericarditis; myocarditis; inflammatory cardiomyopathy; echocardiography; nuclear techniques; cardiac computed tomography; cardiovascular magnetic resonance; arrhythmia; heart failure
(This special issue belongs to the Section Cardiology)
Current Advances in Dysphagia Assessment and Management
edited by
submission deadline 20 May 2027 | 1 articles | Viewed by 158 | Submission Open
Keywords: dysphagia; pathophysiology; swallowing; assessment; swallowing surgery; clinical outcomes
(This special issue belongs to the Section Otolaryngology)
Clinical Management for Metabolic Syndrome and Obesity: 2nd Edition
edited by and Antonio De Arriba-Muñoz
submission deadline 20 May 2027 | 1 articles | Viewed by 98 | Submission Open
Keywords: obesity; metabolic syndrome; hepatic steatosis; diabetes mellitus; children; GLP-1
(This special issue belongs to the Section Endocrinology & Metabolism)
Advanced Technologies in Prenatal Screening and Maternal Fetal Medicine
edited by Jeffrey Denney, Joshua Nitsche and Matthew Zuber
submission deadline 20 May 2027 | Viewed by 93 | Submission Open
Keywords: prenatal diagnosis; prenatal genetic testing; carrier screening; advances in fetal care; advances in prenatal ultrasound
(This special issue belongs to the Section Obstetrics & Gynecology)
Contemporary Advances in Abdominal Surgery: Precision Care, Digital Innovation, and Future Perspectives
edited by Calin Molnar
submission deadline 20 May 2027 | Viewed by 93 | Submission Open
Keywords: abdominal surgery; precision surgery; digital surgery; artificial intelligence; minimally invasive surgery; surgical oncology; perioperative care
(This special issue belongs to the Section General Surgery)
Rhinitis and Rhinosinusitis: Advances in Biomarker Discovery and Therapeutic Innovation
edited by Lara Derycke
submission deadline 20 May 2027 | Viewed by 83 | Submission Open
Keywords: rhinitis; rhinosinusitis; chronic rhinosinusitis; nasal polyps; nasal surgery; precise medicine; biomarker
(This special issue belongs to the Section Otolaryngology)
Innovations in Endovascular Treatment of Thoracic, Thoracoabdominal and Abdominal Aortic Aneurysms
edited by , Enrico Gallitto and
submission deadline 20 May 2027 | Viewed by 81 | Submission Open
Keywords: endovascular aortic repair; TEVAR; EVAR; fenestrated endovascular repair; branched endovascular repair; aortic arch repair; physician-modified endograft; hostile neck anatomy; clinical application of 3D printing; artificial intelligence; aortic remodelling; robotic aortic surgery
(This special issue belongs to the Section Vascular Medicine)
Surgical Management of Brain–Spinal Cord–Nerve Axis Disorders
edited by Ismail Zaed
submission deadline 20 May 2027 | Viewed by 79 | Submission Open
Keywords: neurosurgery; brain disorders; spinal cord pathology; peripheral nerve disorders; surgical management
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Multidisciplinary Emergency and Acute Disease Management: Risk, Triage and Clinical Strategies to Improve Patient Outcomes
edited by Aikaterini Apostolopoulou
submission deadline 20 May 2027 | Viewed by 77 | Submission Open
Keywords: emergency medicine; acute care; risk stratification; triage; patient outcomes
(This special issue belongs to the Section Emergency Medicine)
Strategies and Outcomes in Complex Cardiac Surgery
edited by Mohammed Morjan, Mateo Marin-Cuartas and Carlos Alberto Mestres
submission deadline 20 May 2027 | Viewed by 70 | Submission Open
Keywords: complex cardiac surgery; infective endocarditis; aortic dissection; aortic arch surgery; surgical innovation; hybrid pro-cedures; cerebral protection; surgical outcomes
(This special issue belongs to the Section Cardiology)
Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia (BPH): From Prevention to Diagnosis to Cure
edited by Ilias Giannakodimos
submission deadline 20 May 2027 | Viewed by 69 | Submission Open
Keywords: BPH; LUTS; minimally invasive surgery; diagnosis; treatment; prostate
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Outcome Measurement and Prediction in Spine Surgery
edited by and Il Choi
submission deadline 20 May 2027 | Viewed by 68 | Submission Open
Keywords: patient-reported outcome measures; spine surgery; endoscopic spine surgery; minimally invasive spine surgery; outcome prediction; machine learning; electronic PROM; measurement timing; patient expectations; clinical outcomes; AI; predictive modeling
(This special issue belongs to the Section Clinical Neurology)
Thoracolumbar Spine Injuries: Current Concepts and Future Directions submission deadline 20 May 2027 | Viewed by 68 | Submission Open
Keywords: thoracolumbar spine trauma; burst fracture; AO Spine classification; clinical trials; epidemiology; sex and gender; Hounsfield units; artificial intelligence; minimally invasive surgery; individualized care
(This special issue belongs to the Section Orthopedics)
Modern Clinical Approaches to Cholestic Liver Diseases and Its Complications: Diagnosis, Prognosis, and Treatment
edited by
submission deadline 20 May 2027 | Viewed by 68 | Submission Open
Keywords: cholestatic liver disease; primary biliary cholangitis (PBC); primary sclerosing cholangitis (PSC); portal hypertension; cirrhosis; decompensation; cholangiocarcinoma; hepatocellular carcinoma
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Clinical Advances in Endodontics
edited by Carlo Gaeta and
submission deadline 20 May 2027 | Viewed by 62 | Submission Open
Keywords: root canal treatment; endodontics; systemic diseases and apical periodontitis; irrigation; risk factors; new antimicrobial peptides; regenerative endodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases and Autoimmune Disorders: 2nd Edition
edited by Merav Lidar and
submission deadline 20 May 2027 | Viewed by 62 | Submission Open
Keywords: rheumatic diseases; autoinflammatory diseases; autoimmune disorders; rheumatoid arthritis; diagnosis
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Acute and Intermediate Critical Care: Management and Monitoring of High-Risk Medical Patients
edited by
submission deadline 20 May 2027 | Viewed by 61 | Submission Open
Keywords: intermediate care unit; critical care; emergency medicine; acute care; high-risk patients; sepsis; acute respiratory failure; non-invasive ventilation; hemodynamic monitoring; artificial intelligence; clinical decision support; point-of-care ultrasound; risk stratification; patient monitoring; critical illness
(This special issue belongs to the Section Emergency Medicine)
Recent Advances in Imaging and Interventional Techniques for Prostate Cancer
edited by Francesco Ziglioli and Umberto Vittorio Maestroni
submission deadline 20 May 2027 | Viewed by 60 | Submission Open
Keywords: prostate cancer; pobotic-assisted and focal therapies; artificial intelligence; radiomics image-guided interventions; multiparametric MRI; PSMA-PET/CT
(This special issue belongs to the Section Nephrology & Urology)
Next-Generation Approaches to Out-of-Hospital Cardiac Arrest: From Triage to Post-Resuscitation Care
edited by Young Sun Ro, and Seok-Jin Ryu
submission deadline 20 May 2027 | Viewed by 56 | Submission Open
Keywords: out-of-hospital cardiac arrest; resuscitation; field triage; predictive modeling; artificial intelligence; digital healthcare; post-resuscitation care; neuroprognostication
(This special issue belongs to the Section Emergency Medicine)
Innovations and Clinical Advances in Endovascular Neurosurgery
edited by
submission deadline 20 May 2027 | Viewed by 55 | Submission Open
Keywords: endovascular neurosurgery; mechanical thrombectomy; intracranial aneurysm; flow diversion; arteriovenous malformation; acute ischemic stroke; neurointervention; cerebrovascular disease; minimally invasive techniques; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Renal Inflammation and Fibrosis and Retroperitoneal Fibroinflammatory Diseases: Molecular Mechanisms, Clinical Challenges, and Emerging Therapies
edited by
submission deadline 20 May 2027 | Viewed by 54 | Submission Open
Keywords: retroperitoneal fibrosis, renal fibrosis; IgG4-related disease (IgG4-RD); Erdheim-Chester Disease; lupus nephritis; systemic vasculitis; chronic periaortitis; chronic tubulointerstitial nephritis; obstructive nephropathy; fibroinflam-matory disorders; antifibrotic therapies; biomarkers
(This special issue belongs to the Section Nephrology & Urology)
Advances in Ultrasound Imaging for Pulmonary Diseases
edited by Natalia Buda and
submission deadline 20 May 2027 | Viewed by 54 | Submission Open
Keywords: lung ultrasound; thoracic ultrasound; POCUS; respiratory medicine; interstitial lung diseases; pneumonia; acute respiratory failure; pleural diseases; pulmonary edema; pulmonary embolism; interventional pulmonology; critical care; heart failure; artificial intelligence
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Radiology and Nuclear Medicine for Precision Medical Care: Bridging Innovation from Bench to Patient
edited by
submission deadline 20 May 2027 | Viewed by 54 | Submission Open
Keywords: radiology; precision medicine; diagnostic imaging; emergency radiology; computed tomography (CT); magnetic resonance imaging (MRI); multimodality imaging; quantitative imaging; imaging biomarkers; oncologic imaging; cancer imaging; prostate cancer imaging; renal tumors; pulmonary embolism; thoracic imaging; chest imaging; cardiac CT; abdominal imaging; trauma
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Current Perspectives on Coronary Artery Disease
edited by
submission deadline 20 May 2027 | Viewed by 51 | Submission Open
Keywords: ischemic heart disease; coronary artery disease; prevention strategies; treatment options; multidisciplinary approach; interven-tional cardiology; research lines; bifurcation lesions; chronic total occlusion
(This special issue belongs to the Section Cardiology)
Obstructive Sleep Apnoea: Risk Factors, Associated Disorders, and Variability in Disease Severity
edited by Amro Daboul
submission deadline 20 May 2027 | Viewed by 51 | Submission Open
Keywords: obstructive sleep apnoea; interdisciplinary sleep medicine; risk factors; associated disorders; disease severity
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Gynecological Cancers and Precancerous Lesions: Diagnosis and Treatment for Better Outcomes
edited by Demetra Gabriela Socolov
submission deadline 20 May 2027 | Viewed by 49 | Submission Open
Keywords: gynecological cancers; precancerous lesions; HPV infection; cervical intraepithelial neoplasia; biomarkers; epigenetics; microbiota; molecular diagnostics; IOTA; IETA
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in Autoimmune Disorders—2nd Edition submission deadline 20 May 2027 | Viewed by 49 | Submission Open
Keywords: autoimmune disorders; systemic sclerosis; connective tissue diseases; biomarkers; precision medicine; fibrosis; autoimmunity; immunology; targeted therapies; real-world evidence; artificial intelligence; cardiovascular complications
(This special issue belongs to the Section Immunology & Rheumatology)
Cardiac Ablation: Emerging Technologies, Techniques, and Clinical Evidence
edited by and Mariusz Kowalewski
submission deadline 20 May 2027 | Viewed by 48 | Submission Open
Keywords: atrial fibrillation; arrhythmia; hybrid ablation; electrophysiology; cardiac surgery; pulsed field ablation; cardiac anatomy
(This special issue belongs to the Section Cardiology)
Current Advances and Insights in Chronic Pain Management
edited by Héctor García-López
submission deadline 20 May 2027 | Viewed by 48 | Submission Open
Keywords: chronic pain management; musculoskeletal pain; fibromyalgia; physiotherapy interventions; rehabilitation; therapeutic exercise; physical agents; dry needling; manual therapy; pain neuroscience education; virtual reality-based rehabilitation; telerehabilitation; non-pharmacological interventions; randomized controlled trials; systematic reviews and meta-analyses
(This special issue belongs to the Section Clinical Neurology)
Aortic Dissection: Clinical Diagnosis and Treatment for Better Outcomes
edited by Ilaria Franzese and Daniele Linardi
submission deadline 20 May 2027 | Viewed by 48 | Submission Open
Keywords: aortic imaging; aortic surgery; endovascular treatment; aortic dissection; cerebral perfusion; aortic valve
(This special issue belongs to the Section Cardiology)
Current Advances in Clinical Rehabilitation and Physiotherapy for Musculoskeletal Disorders
edited by
submission deadline 20 May 2027 | Viewed by 41 | Submission Open
Keywords: differential diagnosis; screening for referral; spinal manipulation; low back pain; thoracic pain; neck pain; musculoskeletal disorders; physiotherapy
(This special issue belongs to the Section Clinical Rehabilitation)
Application of Imaging in Liver Diseases
edited by Hideaki Ishida
submission deadline 20 May 2027 | Viewed by 41 | Submission Open
Keywords: liver; ultrasound; imaging; fibrosis; gastroenterology; digestive system diseases; hepatology; cholecystitis; hepatocellular carcinoma; chronic liver disease
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Contemporary Approaches to Heart Failure: Diagnosis and Therapy
edited by
submission deadline 20 May 2027 | Viewed by 40 | Submission Open
Keywords: heart failure; SGLT2 inhibitors; pulmonary hypertension; ATTR-CM; transcatheter structural intervention
(This special issue belongs to the Section Cardiology)
What’s New in Head and Neck Surgery
edited by Marios Stavrakas
submission deadline 20 May 2027 | Viewed by 36 | Submission Open
Keywords: ENT; head and neck oncology; head and neck surgery; transoral robotic surgery (TORS); sinonasal and skull base surgery; minimally invasive surgery; microvascular reconstruction
(This special issue belongs to the Section Otolaryngology)
Psoriasis as a Systemic Disease: Cardiometabolic, Psychiatric, and Multisystem Comorbidities submission deadline 20 May 2027 | Viewed by 3 | Submission Open
Keywords: psoriasis; systemic inflammation; comorbidities; cardiovascular disease; metabolic syndrome; psychiatric comorbidities; infections
(This special issue belongs to the Section Dermatology)
Diastolic Heart Failure: Latest Advances and Prospects submission deadline 20 May 2027 | Viewed by 1 | Submission Open
Keywords: heart failure with preserved ejection fraction (HFpEF); cardiovascular–kidney–metabolic syndrome; diastolic dysfunction; left ventricular contractility; myocardial fibrosis; allograft vasculopathy; atrial fibrillation; ablation of incident atrial fibrillation; functional mitral regurgitation; cardiorenal syndrome; chronic renal disease; fluid retention; central obesity; visceral adiposity inflammation; epicardial adipose tissue; magnetic resonance imaging
(This special issue belongs to the Section Cardiovascular Medicine)
Tumor Microenvironment in Translational Oncology: Histopathological Biomarkers and Therapeutic Targets
edited by Valeria Zuccalà
submission deadline 21 May 2027 | Viewed by 68 | Submission Open
Keywords: tumor microenvironment; translational pathology; tumor budding; invasive front; cancer-associated fibroblasts; tumor-associated macrophages; angiogenesis; lymphangiogenesis; mast cells; immune landscape; immunohistochemistry; digital pathology; spatial pathology; predictive biomarkers; therapeutic targets
(This special issue belongs to the Section Oncology)
Recent Clinical Advances and Challenges in Oral and Maxillofacial Surgery
edited by Majeed Rana and
submission deadline 25 May 2027 | Viewed by 393 | Submission Open
Keywords: oral and maxillofacial surgery; virtual surgical planning; patient-specific implants; 3D printing and additive manufacturing; computer-assisted surgery; artificial intelligence; orthognathic surgery; craniomaxillofacial reconstruction
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
From Psychological Distress to Well-Being: Prevention and Interventions Across Clinical and Applied Settings
edited by Dominika Wilczyńska
submission deadline 25 May 2027 | Viewed by 158 | Submission Open
Keywords: psychological well-being; mental health; psychological distress; depression; high-functioning depression; burnout; resilience; physical activity; exercise interventions; positive psychology
(This special issue belongs to the Section Mental Health)
Clinical Advances in Dyslipidemia
edited by Beatriz Candás-Estébanez
submission deadline 25 May 2027 | Viewed by 52 | Submission Open
Keywords: characterization of lipoproteins; cardiovascular risk; individualized approach; risk stratification tools; novel biomarkers; dyslipidemia; atherosclerosis; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Symptoms and Treatment of Parkinson’s Disease: 2nd Edition
edited by and Nikolaos Papagiannakis
submission deadline 25 May 2027 | Viewed by 49 | Submission Open
Keywords: Parkinson’s disease; non-motor symptoms; clinical progression; cognitive assessment; genetics; remote monitoring; biomarkers; personalized medicine; device-aided treatments; disease-modifying therapies
(This special issue belongs to the Section Clinical Neurology)
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