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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Surgical Innovations in Pediatric Orthopedics
edited by
submission deadline 25 Jun 2026 | Viewed by 24 | Submission Open
Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing
(This special issue belongs to the Section Orthopedics)
Diagnosis and Management of Corneal Diseases
edited by Nicola Cardascia
submission deadline 25 Jun 2026 | Viewed by 22 | Submission Open
Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation
(This special issue belongs to the Section Ophthalmology)
Geriatric Cardiology: Clinical Advances and Comprehensive Management
edited by
submission deadline 25 Jun 2026 | Viewed by 22 | Submission Open
Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management
(This special issue belongs to the Section Geriatric Medicine)
Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications
edited by
submission deadline 25 Jun 2026 | Viewed by 21 | Submission Open
Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa
(This special issue belongs to the Section Ophthalmology)
Oral Health and Systemic Diseases: Clinical Insights
edited by
submission deadline 25 Jun 2026 | Viewed by 19 | Submission Open
Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition
edited by
submission deadline 25 Jun 2026 | Viewed by 18 | Submission Open
Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure
(This special issue belongs to the Section Cardiology)
Advances in Immunohematology: From Pathophysiology to Tailored Treatments submission deadline 25 Jun 2026 | Viewed by 14 | Submission Open
Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination
(This special issue belongs to the Section Immunology & Rheumatology)
Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition submission deadline 25 Jun 2026 | Viewed by 12 | Submission Open
Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies submission deadline 25 Jun 2026 | Viewed by 10 | Submission Open
Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities
(This special issue belongs to the Section Epidemiology & Public Health)
Clinical Management of Traumatic Brain Injury
edited by Adam James Wells and Peter Hutchinson
submission deadline 25 Jun 2026 | Viewed by 10 | Submission Open
Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence
(This special issue belongs to the Section Clinical Neurology)
Advances in Minimally Invasive and Endoscopic Neurosurgery
edited by Shunsuke Shibao
submission deadline 25 Jun 2026 | Viewed by 4 | Submission Open
Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery
(This special issue belongs to the Section Clinical Neurology)
Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases
edited by
submission deadline 25 Jun 2026 | Viewed by 3 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives
edited by Shintaro Chiba
submission deadline 25 Jun 2026 | Viewed by 1 | Submission Open
Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology
(This special issue belongs to the Section Respiratory Medicine)
Cystic Fibrosis: Management Strategies and Patient Outcomes
edited by Marta Rachel
submission deadline 25 Jun 2026 | Submission Open
Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management
(This special issue belongs to the Section Respiratory Medicine)
Advances in General and Regional Anaesthesia
edited by Michał Jan Stasiowski, and
submission deadline 26 Jun 2026 | Viewed by 19 | Submission Open
Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia
(This special issue belongs to the Section Anesthesiology)
Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management
edited by Joanna F. Blackburn
submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics
(This special issue belongs to the Section Dermatology)
Clinical Advances in Aortic Disease and Revascularization: 2nd Edition
edited by Andrej Udelnow
submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open
Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound
(This special issue belongs to the Section Vascular Medicine)
Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management
edited by and Deborah Alperovitch
submission deadline 30 Jun 2026 | Viewed by 7 | Submission Open
Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics
(This special issue belongs to the Section Orthopedics)
Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside submission deadline 10 Jul 2026 | Viewed by 34 | Submission Open
Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers
(This special issue belongs to the Section Respiratory Medicine)
Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives
edited by Pier Alberto Testoni
submission deadline 10 Jul 2026 | Viewed by 5 | Submission Open
Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics
edited by Dafni Charisopoulou and
submission deadline 10 Jul 2026 | Submission Open
Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure
(This special issue belongs to the Section Cardiology)
Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery
edited by , Rareș Calin Roman and Mihaela Carmen Hedeşiu
submission deadline 15 Jul 2026 | Viewed by 356 | Submission Open
Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Fertility Challenges: Modern Management Strategies and Assisted Reproductive Technologies
edited by
submission deadline 15 Jul 2026 | Viewed by 15 | Submission Open
Keywords: infertility; assisted reproductive technologies (ARTs); ovarian reserve; antral follicle count (AFC); anti-mullerian hormone (AMH); fertility preservation; IVF pregnancy; ovarian stimulation; embryo selection
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery
edited by Shingo Tsujinaka
submission deadline 15 Jul 2026 | Viewed by 8 | Submission Open
Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes
(This special issue belongs to the Section General Surgery)
Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment submission deadline 15 Jul 2026 | Viewed by 8 | Submission Open
Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment
(This special issue belongs to the Section Orthopedics)
Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders
edited by and Sylwia Krzemińska
submission deadline 15 Jul 2026 | Viewed by 1 | Submission Open
Keywords: risk factors; secondary prevention; health education; health behaviors
(This special issue belongs to the Section Clinical Rehabilitation)
Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options
edited by Przemysław Puz, and
submission deadline 15 Jul 2026 | Viewed by 1 | Submission Open
Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection
(This special issue belongs to the Section Clinical Neurology)
Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management
edited by Babar Khan Rao
submission deadline 20 Jul 2026 | Viewed by 88 | Submission Open
Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management
(This special issue belongs to the Section Dermatology)
Clinical Implications of Artificial Intelligence in Patient Care
edited by and
submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open
Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI
(This special issue belongs to the Section Clinical Research Methods)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management
edited by Olga Reitblat
submission deadline 20 Jul 2026 | Viewed by 17 | Submission Open
Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry
(This special issue belongs to the Section Ophthalmology)
Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation
edited by
submission deadline 20 Jul 2026 | Viewed by 16 | Submission Open
Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures
(This special issue belongs to the Section Orthopedics)
Current Advances and Future Perspectives in Cardiothoracic Surgery
edited by Tomislav Kopjar
submission deadline 20 Jul 2026 | Viewed by 8 | Submission Open
Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities
(This special issue belongs to the Section General Surgery)
Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice submission deadline 20 Jul 2026 | Viewed by 7 | Submission Open
Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging
(This special issue belongs to the Section Sports Medicine)
Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention
edited by Marco Ciardetti and Alessio Mattesini
submission deadline 20 Jul 2026 | Viewed by 6 | Submission Open
Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification
(This special issue belongs to the Section Cardiology)
Orthodontics: Current Management and Future Options
edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė
submission deadline 20 Jul 2026 | Viewed by 5 | Submission Open
Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives
edited by Jeffrey B. Velotta and
submission deadline 20 Jul 2026 | Viewed by 5 | Submission Open
Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery
(This special issue belongs to the Section General Surgery)
Advances in the Management of Cough and Asthma
edited by Ebymar Arismendi
submission deadline 20 Jul 2026 | Submission Open
Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma
(This special issue belongs to the Section Respiratory Medicine)
Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease
edited by and Aleksander Dokollari
submission deadline 20 Jul 2026 | Submission Open
Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement
(This special issue belongs to the Section Cardiology)
New Perspective of Oral and Maxillo-Facial Surgery:2nd Edition
edited by , and Alessandra Lucchese
submission deadline 20 Jul 2026 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
High-Risk Pregnancy Management: From Prenatal Care to Postpartum Outcomes
edited by Angela Vinturache
submission deadline 25 Jul 2026 | Viewed by 23 | Submission Open
Keywords: high-risk pregnancy; prenatal care; postpartum outcomes; postpartum mental health; birth trauma; AI in obstetrics; medico-legal liability; equity & culturally safe care; indigenous and rural/remote care; EMR-enabled decision support; quality trend monitoring; maternal morbidity and mortality; perinatal morbidity; standardized care bundles & pathways
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock
edited by Giulia Maj
submission deadline 25 Jul 2026 | Viewed by 6 | Submission Open
Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest
(This special issue belongs to the Section Emergency Medicine)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Jul 2026 | Viewed by 47 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Neurovascular Canvas: From Basic Science to Clinical Breakthroughs
edited by , Nicola Giannini and
submission deadline 15 Aug 2026 | Viewed by 31 | Submission Open
Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling
(This special issue belongs to the Section Clinical Neurology)
Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 36 | Submission Open
Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI
(This special issue belongs to the Section Cardiovascular Medicine)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1131 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications
edited by , Tilo Kölbel and José Ignacio F. Torrealba
submission deadline 20 Jul 2027 | Viewed by 72 | Submission Open
Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes
(This special issue belongs to the Section Vascular Medicine)
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