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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Prostate Surgery: The Latest Advances and Future Trends
edited by Akhil K. Das and
submission deadline 28 Oct 2025 | Viewed by 151 | Submission Open
Keywords: benign prostatic hyperplasia (BPH); minimally invasive surgical therapies (MIST); laser enucleation (HoLEP; ThuLEP); Aquablation; Rezum; robotic prostatectomy; anatomic enucleation
(This special issue belongs to the Section Nephrology & Urology)
Symptoms and Treatment of Cardiac Amyloidosis
edited by Syed Bukhari
submission deadline 28 Oct 2025 | Viewed by 135 | Submission Open
Keywords: cardiac amyloidosis; transthyretin amyloidosis; light chain amyloidosis; cardiac magnetic resonance; echocardiography; nuclear scintigraphy; endomyocardial biopsy; gene silencers; transthyretin stabilizers; immunotherapy
(This special issue belongs to the Section Cardiology)
Recent Advances and Clinical Outcomes of Hip and Knee Arthroplasty
edited by
submission deadline 28 Oct 2025 | Viewed by 99 | Submission Open
Keywords: hip arthroplasty; knee arthroplasty; joint replacement; clinical outcomes; surgical innovation; patient recovery; prosthetics; perioperative care
(This special issue belongs to the Section Orthopedics)
Diagnosis, Treatment, and Management of Gastrointestinal Oncology
edited by Toufic A. Kachaamy and Madappa N. Kundranda
submission deadline 30 Oct 2025 | 3 articles | Viewed by 8963 | Submission Open
Keywords: gastrointestinal oncology; endoscopic oncology; biliary tract cancer; colorectal cancer; esophageal cancer; stomach cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Biomarkers and Lung Cancer: Clinical Application
edited by
submission deadline 30 Oct 2025 | 5 articles | Viewed by 5845 | Submission Open
Keywords: lung cancer; early diagnosis; prognosis; biomarkers; body fluids; liquid biopsy
(This special issue belongs to the Section Respiratory Medicine)
New Update on Personalized Treatment of Autism Spectrum Disorder and Related Disorders
edited by , Rosamaria Siracusano and Erica Pironti
submission deadline 30 Oct 2025 | 2 articles | Viewed by 4852 | Submission Open
Keywords: autism spectrum disorder; autism related disorders; children and adolescents; intervention strategies; therapeutic advance; new technologies; evidence-based practices
(This special issue belongs to the Section Mental Health)
Advances in Anesthesia for Cardiac Surgery
edited by Christopher M. Munch and
submission deadline 30 Oct 2025 | 5 articles | Viewed by 4785 | Submission Open
Keywords: enhanced recovery after cardiac surgery (ERACS); minimally invasive cardiac surgery (MICS); ultra-fast-track an-esthesia; chest wall blocks in cardiac anesthesia; opioid-free anesthesia in cardiac surgery; neurologic dysfunction and cardiac surgery; pre- and posthabilitation in cardiac surgery
(This special issue belongs to the Section Anesthesiology)
Clinical Highlights in Chronic Obstructive Pulmonary Disease (COPD)
edited by and Dimosthenis Lykouras
submission deadline 30 Oct 2025 | 4 articles | Viewed by 4013 | Submission Open
Keywords: COPD treatment; inhalers; patient-reported outcomes; COPD rehabilitation; cardiovascular risk
(This special issue belongs to the Section Respiratory Medicine)
Clinical Challenges in High-Risk Pregnancy and Delivery submission deadline 30 Oct 2025 | 1 articles | Viewed by 3064 | Submission Open
Keywords: high-risk pregnancy; preeclampsia; cesarean section; maternal– fetal medicine; ultrasound; fetal monitoring; complications; delivery; placental abruption; great obstetrical syndromes
(This special issue belongs to the Section Obstetrics & Gynecology)
Facial Plastic and Cosmetic Medicine
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 2614 | Submission Open
Keywords: cosmetics; aesthetics; plastic surgery; skin rejuvenation; beauty; procedures
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Advances in Minimally Invasive Surgery for Gynecologic Cancer submission deadline 30 Oct 2025 | 1 articles | Viewed by 2548 | Submission Open
Keywords: minimally invasive surgery; gynecologic surgery; gynecologic oncology; surgical techniques; patient safety; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Spine Surgery: Current Practice and Future Directions
edited by Claudio Bernucci and Francesco Costa
submission deadline 30 Oct 2025 | 1 articles | Viewed by 1699 | Submission Open
Keywords: degenerative; spinal trauma; spine tumors; neurosurgery; spine surgery; spinal deformity; scoliosis; robotics surgery; spinal cord injury; clinical practices; regenerative therapies
(This special issue belongs to the Section Clinical Neurology)
Advances in Anesthesia and Intensive Care During Perioperative Period
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1074 | Submission Open
Keywords: general anesthesia; intensive care medicine; post intensive care syndrome; perioperative management; fast track; pain management; complications; postoperative outcome; digitalization; big data; AI; closed-loop systems; machine learning; clinical decision support; telemedicine
(This special issue belongs to the Section Intensive Care)
Advancements and Challenges in Reconstructive Urology and Urethral Surgery
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1048 | Submission Open
Keywords: reconstructive urology; urethral surgery; urethroplasty; minimally invasive surgery; robotic-assisted surgery; urinary tract reconstruction; surgical innovation; patient-reported outcomes
(This special issue belongs to the Section Nephrology & Urology)
Innovations in Perioperative Anesthesia and Intensive Care
edited by and Ileana Lulic
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1030 | Submission Open
Keywords: perioperative anesthesia; intensive care; artificial intelligence in anesthesia; precision medicine in perioperative care; hemodynamic monitoring; multimodal analgesia; opioid-free anesthesia; ventilation strategies in ICU and surgery; neuromonitoring and sedation; perioperative resuscitation and ECMO
(This special issue belongs to the Section Intensive Care)
Artificial Intelligence and Deep Learning in Medical Imaging
edited by Eros Montin and Giuseppe Carluccio
submission deadline 30 Oct 2025 | 2 articles | Viewed by 766 | Submission Open
Keywords: magnetic resonance imaging; radiomics; artificial intelligence (AI); deep learning; clinical and translational medicine; MRI safety; radiogenomics; multiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Advances in Ocular Surface Research: Exploring Antimicrobial Resistance and Emerging Therapeutics
edited by , Giovanni Alessio and Maria Gabriella la Tegola
submission deadline 30 Oct 2025 | 1 articles | Viewed by 753 | Submission Open
Keywords: ocular surface microbiome; antimicrobial resistance; ocular infections and therapeutics; novel diagnostics in ophthalmology; biofilms and pathogen evolution; infection control and public health
(This special issue belongs to the Section Ophthalmology)
Prostatectomy: Clinical Updates and Perspectives
edited by Antonio Nacchia
submission deadline 30 Oct 2025 | 1 articles | Viewed by 749 | Submission Open
Keywords: single port; prostatectomy; robotics; RARP; prostate cancer
(This special issue belongs to the Section Nephrology & Urology)
Prosthetic Joint Infections: Contemporary Insights into Their Management and Prevention
edited by and Uwe Maus
submission deadline 30 Oct 2025 | 1 articles | Viewed by 581 | Submission Open
Keywords: arthroplasty; infection; replacement; antibiotics; management; hip; knee; shoulder; periprosthetic; prevention; implant retention; procedure; implant retention; debridement; cellular infection; infection markers
(This special issue belongs to the Section Orthopedics)
Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy
edited by , Francesco Costa and Filippo Maria Polli
submission deadline 30 Oct 2025 | 1 articles | Viewed by 538 | Submission Open
Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction
(This special issue belongs to the Section Clinical Neurology)
Advances in Atrial Fibrillation Treatment
edited by Iwona Woźniak-Skowerska
submission deadline 30 Oct 2025 | 1 articles | Viewed by 413 | Submission Open
Keywords: pulmonary vein ablation; atrial fibrillation; heart failure; arrhythmia; personalized medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Advancements in Venous Thrombosis Management: From Prevention to Long-Term Care
edited by
submission deadline 30 Oct 2025 | Viewed by 392 | Submission Open
Keywords: venous thromboembolism; post-thrombotic syndrome; direct oral anticoagulant; pulmonary embolism; thrombosis; factor xia inhibitors; thrombolysis; cancer; antiphospholipid syndrome; catheter-directed thrombolysis; inferior vena cava filters
(This special issue belongs to the Section Vascular Medicine)
Advances in Gastroenterological Surgery
edited by Alan Biloslavo and Antonio La Greca
submission deadline 30 Oct 2025 | Viewed by 287 | Submission Open
Keywords: mini-invasive surgery; technology; artificial intelligence; negative pressure; indocyanine green; ultrasound; GE surgery; emergency surgery; precision surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Drug Therapy and Prognosis in Patients with Heart Failure submission deadline 30 Oct 2025 | Viewed by 160 | Submission Open
Keywords: heart failure; drug therapy; prognosis; pharmacological innovations; cardiovascular outcomes; personalized medicine; heart failure management
(This special issue belongs to the Section Cardiology)
Clinical Update on Thoracic Trauma
edited by
submission deadline 30 Oct 2025 | Viewed by 152 | Submission Open
Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation
(This special issue belongs to the Section Respiratory Medicine)
Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges
edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck
submission deadline 30 Oct 2025 | Viewed by 148 | Submission Open
Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability
(This special issue belongs to the Section Cardiology)
Myeloproliferative Neoplasms (MPN): Recent Advances, Current Practices and Future Perspectives
edited by Arumugam Manoharan
submission deadline 31 Oct 2025 | 7 articles | Viewed by 13191 | Submission Open
Keywords: diagnosis; pathogenesis; prognosis; thromboprophylaxis; treatment
(This special issue belongs to the Section Hematology)
Progress in Patient Safety and Quality in Maternal–Fetal Medicine
edited by Samuel T. Bauer
submission deadline 31 Oct 2025 | 8 articles | Viewed by 11060 | Submission Open
Keywords: maternal– fetal medicine; pregnancy; postpartum; medical error; maternity; fetus
(This special issue belongs to the Section Obstetrics & Gynecology)
Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring
edited by Zhicheng Jin
submission deadline 31 Oct 2025 | 1 articles | Viewed by 6641 | Submission Open
Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids
(This special issue belongs to the Section Pharmacology)
Current Advances in Endodontics and Dental Traumatology
edited by Karin Christine Huth
submission deadline 31 Oct 2025 | 7 articles | Viewed by 5784 | Submission Open
Keywords: endodontology; traumatology; regeneration; biocompatibility; dental materials; antimicrobial; dynamic and static navigation in endodontics; under- and postgraduate education in endodontology and traumatology; artificial intelligence; autotransplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Chronic Renal Disease: Diagnosis, Treatment, and Management
edited by
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3838 | Submission Open
Keywords: acute kidney injury; chronic kidney disease; cardio– renal syndromes; clinical nephrology; diagnosis and management
(This special issue belongs to the Section Nephrology & Urology)
Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition submission deadline 31 Oct 2025 | 4 articles | Viewed by 3038 | Submission Open
Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Grand Challenges in the Diagnosis and Management of Cardiovascular and Cerebrovascular Diseases
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 2585 | Submission Open
Keywords: cardiovascular diseases; cerebrovascular diseases; diagnosis; management; imaging; biomarkers; artificial intelligence; therapeutic strategies; pharmacology; surgery; rehabilitation; multidisciplinary care
(This special issue belongs to the Section Cardiovascular Medicine)
Youth Sports Injuries: From Prevalence to Prevention
edited by Swarup Mukherjee and
submission deadline 31 Oct 2025 | 4 articles | Viewed by 2250 | Submission Open
Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes
(This special issue belongs to the Section Sports Medicine)
Clinical Advances in Abdominal Surgery
edited by and César P. Ramírez-Plaza
submission deadline 31 Oct 2025 | 4 articles | Viewed by 1803 | Submission Open
Keywords: abdominal surgery; oncologic surgery; minimal invasive techniques; HIPEC; PIPAC; peritoneal carcinomatosis; liver metastasis
(This special issue belongs to the Section General Surgery)
Advancing Minimally Invasive Spine Surgery: A Special Edition on Endoscopic Spine Surgery
edited by and Gregory W. Basil
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1682 | Submission Open
Keywords: minimally invasive spine surgery (MIS); endoscopic spine surgery (ESS); spine surgery; percutaneous spine surgery; full-endoscopic spine surgery; biportal endoscopic spine surgery (BESS); unilateral biportal endoscopy (UBE); percutaneous endoscopic lumbar discectomy (PELD); endoscopic decompression; transforaminal endoscopic lumbar discectomy (TELD); interlaminar endoscopic lumbar discectomy (IELD); endoscopic lumbar fusion; endoscopic transforaminal lumbar interbody fusion (Endo-TLIF)
(This special issue belongs to the Section Clinical Neurology)
Cardiogenic Shock and Cardiac Arrest: Updates, Challenges and Opportunities
edited by Torben K. Becker
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1249 | Submission Open
Keywords: cardiac arrest; extracorporeal membrane oxygenation; extracorporeal CPR; cardiopulmonary resuscitation; cardiogenic shock; resuscitation; prognostication
(This special issue belongs to the Section Cardiology)
New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease submission deadline 31 Oct 2025 | Viewed by 1216 | Submission Open
Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations
(This special issue belongs to the Section Cardiovascular Medicine)
Imaging in Diagnosis and Treatment of Musculoskeletal Disorders
edited by Francesco Porta and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1067 | Submission Open
Keywords: ultrasound; ultrasound-guided injections; imaging-guided procedures
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Perspective of Oral and Maxillo-Facial Surgery
edited by , and Alessandra Lucchese
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1036 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Novel Insights into Neonatal Intensive Care
edited by and Maria Baltogianni
submission deadline 31 Oct 2025 | 1 articles | Viewed by 854 | Submission Open
Keywords: neonatology; neonatal intensive care; neonate; sepsis; nutrition; ventilation; hemodynamic; neurodevelopment
(This special issue belongs to the Section Clinical Pediatrics)
Interstitial Lung Diseases: New Treatments and Future Directions
edited by Justyna Fijołek
submission deadline 31 Oct 2025 | 1 articles | Viewed by 803 | Submission Open
Keywords: Interstitial Lung Disease (ILD); pulmonary fibrosis; orphan lung disease; AAV-ILD; occupational ILD; rheumatic lung disease; treatment strategies; emerging therapies; precision medicine; future directions
(This special issue belongs to the Section Respiratory Medicine)
Clinical Care and Rehabilitation for Neuromuscular Diseases submission deadline 31 Oct 2025 | Viewed by 752 | Submission Open
Keywords: neuromuscular diseases; myopathy; neuropathy; motor neuron disease; amyotrophic lateral sclerosis; diseases of neuromuscular junction; neurorehabilitation; rehabilitation; clinical care; neuroscience
(This special issue belongs to the Section Clinical Rehabilitation)
Emerging Diagnostic and Treatment Approaches for Gynecological Cancers
edited by Marco D'Indinosante
submission deadline 31 Oct 2025 | 2 articles | Viewed by 726 | Submission Open
Keywords: gynecologic oncology; surgical gynecology; biomarkers; endometrial carcinoma; ovarian carcinoma; cervical carcinoma
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Management of Pediatric Heart Diseases
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 676 | Submission Open
Keywords: pediatric heart diseases; children; pediatric cardiology; congenital heart disease; clinical management; congenital heart surgery; outcome
(This special issue belongs to the Section Clinical Pediatrics)
Novel Technologies to Assist Emergency Medical Care
edited by and Young Soon Cho
submission deadline 31 Oct 2025 | 1 articles | Viewed by 624 | Submission Open
Keywords: emergency medical services; artificial intelligence in emergency medicine; telemedicine and remote patient monitoring; wearable health technologies; point-of-care diagnostics; automated decision support systems; robotics in emergency medicine; pre-hospital care innovations
(This special issue belongs to the Section Emergency Medicine)
Advances and Future Directions in Percutaneous Coronary Intervention (PCI)
edited by Daniele Giacoppo and Antonio Greco
submission deadline 31 Oct 2025 | 1 articles | Viewed by 622 | Submission Open
Keywords: drug-eluting stents; drug-coated balloons; bioresorbable vascular scaffolds; antiplatelet therapy; intravascular ultrasound; optical coherence tomography; quantitative flow ratio; complete revascularization
(This special issue belongs to the Section Cardiology)
Rehabilitation Strategies for Neurological Disorders: Advances and Insights
edited by Delia Cinteză and Mihai Berteanu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 554 | Submission Open
Keywords: neurorehabilitation; physical medicine; virtual reality; AI in rehabilitation medicine; robotic rehabilitation; telerehabilitation; advanced technologies; upper neuromotor lesions; peripheral neuropathies; wearable sensor devices; assessment; goal-setting; individual rehabilitation plan
(This special issue belongs to the Section Clinical Rehabilitation)
Diabetic Retinopathy Screening: Current Advances and Future Options submission deadline 31 Oct 2025 | 1 articles | Viewed by 545 | Submission Open
Keywords: diabetic retinopathy; diabetic retinopathy screening; retinal imaging; age-related macular degeneration; artificial intelli-gence; image analysis; color fundus photography; optical coherence tomography imaging; telemedicine
(This special issue belongs to the Section Ophthalmology)
Advanced Hepato-Pancreato-Biliary Surgery: Clinical Innovations and Improved Outcomes
edited by Ahmad Mahamid and Riad Haddad
submission deadline 31 Oct 2025 | 1 articles | Viewed by 504 | Submission Open
Keywords: liver surgery; pancreas surgery; biliary surgery; robotic HPB surgery; single incision surgery; prognostic biomarkers; perioperative clinical care; postoperative complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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