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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jan 2026 | Viewed by 130 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

edited by

Maria Pina Dore

and

Elettra Merola

submission deadline 15 Jan 2026 | Viewed by 113 | Submission Open

Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Diagnosis and Management of Chronic Venous Diseases

edited by

Sigitas Urbonavičius

submission deadline 15 Jan 2026 | Viewed by 88 | Submission Open

Keywords: varicose veins; chronic venous insufficiency; pathogenesis; operative treatment; conservative treatment; profilaxis

(This special issue belongs to the Section Vascular Medicine)

Novel Sepsis and Post-Sepsis Care: The Heart and Beyond

edited by Alexander Liu and

Barbara J. Philips

submission deadline 16 Jan 2026 | Viewed by 235 | Submission Open

Keywords: sepsis; post sepsis; inflammation; cardiomyopathy; heart failure; cardiac imaging; biomarkers; novel therapies; prognosis; clinical outcomes

Innovations in Plastic and Reconstructive Research

edited by Damiano Tambasco and Roberta Albanese

submission deadline 18 Jan 2026 | 4 articles | Viewed by 5677 | Submission Open

Keywords: microvascular surgery; 3D printing; regenerative medicine; aesthetic surgery; minimally invasive techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 18 Jan 2026 | 1 articles | Viewed by 859 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 19 Jan 2026 | 1 articles | Viewed by 1531 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 20 Jan 2026 | 12 articles | Viewed by 35884 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology & Rheumatology)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives

edited by Ehud I. Assia

submission deadline 20 Jan 2026 | 12 articles | Viewed by 17042 | Submission Open

Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses

(This special issue belongs to the Section Ophthalmology)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 20 Jan 2026 | 9 articles | Viewed by 16789 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Hernia Surgery and Postoperative Management

edited by Jacob Rosenberg

submission deadline 20 Jan 2026 | 5 articles | Viewed by 14615 | Submission Open

Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications

(This special issue belongs to the Section General Surgery)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2026 | 6 articles | Viewed by 14032 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation

edited by

Nikolaos K. Fragakis

and

Paschalis Karakasis

submission deadline 20 Jan 2026 | 4 articles | Viewed by 11610 | Submission Open

Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care

(This special issue belongs to the Section Cardiology)

POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

edited by Svetlana Blitshteyn

submission deadline 20 Jan 2026 | 2 articles | Viewed by 11589 | Submission Open

Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity

(This special issue belongs to the Section Immunology & Rheumatology)

Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting

edited by Federico Raveglia,

Carmelina C. Zirafa

and

Mohsen Ibrahim

submission deadline 20 Jan 2026 | 7 articles | Viewed by 11208 | Submission Open

Keywords: lung cancer; interventional endoscopy; upper airway reconstruction; robotic diagnosis; robotic surgery

(This special issue belongs to the Section Respiratory Medicine)

Foot and Ankle Surgery: State of the Art and Future Perspectives

edited by Sung Jae Kim and Jaehwang Song

submission deadline 20 Jan 2026 | 5 articles | Viewed by 8443 | Submission Open

Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder

(This special issue belongs to the Section Orthopedics)

Oral Health in Children: Clinical Management

edited by

Yolanda Martinez Beneyto

submission deadline 20 Jan 2026 | 7 articles | Viewed by 8423 | Submission Open

Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Traumatic Brain Injury: Current Treatment and Future Options

edited by

Ismail Zaed

submission deadline 20 Jan 2026 | 5 articles | Viewed by 8270 | Submission Open

Keywords: traumatic brain injury; trauma; biomarkers; post-traumatic outcome; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Attention-Deficit/Hyperactivity Disorder (ADHD): Advances in Diagnosis and Treatment

edited by Yanli Zhang-James

submission deadline 20 Jan 2026 | 3 articles | Viewed by 8262 | Submission Open

Keywords: attention-deficit/hyperactivity disorder; neurodevelopmental disorder; hyperactivity; children; adolescents; adult

(This special issue belongs to the Section Clinical Neurology)

Innovative Clinical Approaches in Oral Health Prevention and Management

edited by

Giulia Orilisi

Rossana Izzetti

and Flavia Vitiello

submission deadline 20 Jan 2026 | 6 articles | Viewed by 6934 | Submission Open

Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiovascular Imaging: Opportunities and Challenges in Clinical Application: 3rd Edition

edited by

Kana Fujikura

and Panagiota Christia

submission deadline 20 Jan 2026 | 4 articles | Viewed by 6358 | Submission Open

Keywords: echocardiography; cardiovascular magnetic resonance imaging; cardiovascular computed tomography imaging; nuclear cardiology imaging; stress test with imaging; multimodality cardiovascular imaging; cardiomyopathy; coronary artery disease; microvascular disease; valvular heart disease

(This special issue belongs to the Section Cardiology)

Plastic Surgery: Challenges and Future Directions

edited by Philip Brazio and Edward C. Ray

submission deadline 20 Jan 2026 | 3 articles | Viewed by 6191 | Submission Open

Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Peripheral Nerves: Imaging, Electrophysiology and Surgical Techniques

edited by

Raffaele Natella

, Aniello Iovino and Vito Stifano

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5780 | Submission Open

Keywords: MRI; MSK imaging; soft-tissue tumors; DTI; neuropathies; inflammatory neuropathies; nerve entrapment; motor neuron disease; neurophysiology; MSK ultrasound; peripheral nerve tumor; nerve entrapment; nerve reconstruction

(This special issue belongs to the Section Clinical Neurology)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5522 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care

edited by

Benedetta Muzii

Nelson Mauro Maldonato

and

Andrea Bovero

submission deadline 20 Jan 2026 | 3 articles | Viewed by 5485 | Submission Open

Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors

(This special issue belongs to the Section Mental Health)

Clinical Challenges of Pelvic Floor Disorders Management

edited by

Matteo Frigerio

submission deadline 20 Jan 2026 | 4 articles | Viewed by 5147 | Submission Open

Keywords: pelvic floor disorders; pelvic organ prolapse; urinary incontinence; surgery; diagnostics; pelvic pain; vulvodynia; urinary tract symptoms; mesh-related complications

(This special issue belongs to the Section Obstetrics & Gynecology)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jan 2026 | 4 articles | Viewed by 4746 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Diagnosis, Risk Stratification, and Personalized Management in Acute Coronary Syndromes

edited by

Efstratios Karagiannidis

, Barbara P. Fyntanidou and Aikaterini Apostolopoulou

submission deadline 20 Jan 2026 | 5 articles | Viewed by 4652 | Submission Open

Keywords: acute coronary syndrome (ACS); cardiovascular disease (CVD); ischemic heart disease; emergency medicine; risk stratification; personalized treatment; antiplatelets; primary and secondary prevention

(This special issue belongs to the Section Cardiology)

Eating Disorders: Current Epidemiology and Advances in Diagnosis and Treatment—Second Edition

edited by

Arthur Eumann Mesas

submission deadline 20 Jan 2026 | 4 articles | Viewed by 4154 | Submission Open

Keywords: eating disorder; bulimia nervosa; anorexia nervosa; binge eating disorder; sociocultural context; epidemiology; di-agnosis; treatment; prevention

(This special issue belongs to the Section Mental Health)

Microsurgery: Current and Future Challenges

edited by

Matthias Aitzetmüller-Klietz

submission deadline 20 Jan 2026 | 5 articles | Viewed by 4052 | Submission Open

Keywords: microsurgery; reconstruction; reconstructive surgery; breast reconstruction; extremity reconstruction

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 20 Jan 2026 | 4 articles | Viewed by 3752 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Clinical Insights into Pediatric Critical Care

edited by Katherine Biagas and Daniel E Sloniewsky

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3647 | Submission Open

Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage

(This special issue belongs to the Section Intensive Care)

Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management

edited by Mariana Tudoran and

Cristina Tudoran

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3503 | Submission Open

Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID

(This special issue belongs to the Section Cardiovascular Medicine)

Endodontic Disease: Prevalence, Risk Factors, and Treatment Outcome

edited by

Razvan Ionut Ghinea

Ioana-Sofia Pop-Ciutrilă

and

Luminita-Maria Nica

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3448 | Submission Open

Keywords: endodontics; apical periodontitis; pulpitis; root canal treatment; risk factors; treatment outcomes; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition

edited by Jaime A. Hernández-Montfort

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3418 | Submission Open

Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement

(This special issue belongs to the Section Cardiology)

Artificial Intelligence (AI) and Deep Learning (DL) in Medical Imaging

edited by

Francesco Pucciarelli

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3280 | Submission Open

Keywords: artificial intelligence; deep learning; imaging; diagnosis; precision medicine; oncologic

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 20 Jan 2026 | 3 articles | Viewed by 3213 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Application of Radiotherapy in Modern Oncology

edited by

Lukas Käsmann

and

Fabian Weykamp

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3164 | Submission Open

Keywords: brain metastasis; bone metastasis; brain tumors; head and neck cancers; thoracic oncology; breast cancer; prostate cancer; sarcoma

(This special issue belongs to the Section Oncology)

Sports Injuries: Recent Advances in Prevention and Rehabilitation, 2nd Edition

edited by

Stasinopoulos Dimitrios

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3075 | Submission Open

Keywords: sports injuries; treatment; musculoskeletal disorders; rehabilitation; physical rehabilitation; exercise science; sports science; injury prevention

(This special issue belongs to the Section Sports Medicine)

Current and Emerging Therapies for Rheumatoid Arthritis

edited by

Yoshiro Horai

submission deadline 20 Jan 2026 | 1 articles | Viewed by 3029 | Submission Open

Keywords: DMARDs (disease-modifying anti-rheumatic drugs); boDMARDs (biological DMARDs); bsDMARDs (biosimilar DMARDs); csDMARDs (conventional synthetic DMARDs); rheumatoid arthritis; tsDMARDs (targeted synthetic DMARDs)

(This special issue belongs to the Section Immunology & Rheumatology)

Allergen-Specific Immunotherapy (AIT) for Allergic Diseases of the Respiratory Tract and Food Allergies

edited by

Ralph Mösges

submission deadline 20 Jan 2026 | 2 articles | Viewed by 3021 | Submission Open

Keywords: allergy; allergic rhinitis; allergic conjunctivitis; allergic asthma; food allergy; peptide immunotherapy; allergoids; SLIT; SCIT; OIT

(This special issue belongs to the Section Immunology & Rheumatology)

Recent Clinical Research on Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by Gerond V. Lake-Bakaar

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2996 | Submission Open

Keywords: NAFLD; NASH; cirrhosis; hepatocellular carcinoma; hepatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke

edited by

Fusao Ikawa

submission deadline 20 Jan 2026 | 3 articles | Viewed by 2729 | Submission Open

Keywords: acute ischemic stroke; endovascular treatment; imaging; management of ischemic stroke; system and strategy for acute ischemic stroke; multidisciplinary approach for acute ischemic stroke

(This special issue belongs to the Section Clinical Neurology)

Advances and Trends in Pediatric Surgery

edited by

Nikolaos Zavras

and

Anastasia Dimopoulou

submission deadline 20 Jan 2026 | 3 articles | Viewed by 2670 | Submission Open

Keywords: pediatric surgery; minimally invasive surgery; robotics; trends; advances

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Tuberculosis: Comprehensive Insights and Management Strategies

edited by Aliaksandr Skrahin

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2261 | Submission Open

Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations

(This special issue belongs to the Section Infectious Diseases)

Advances in the Treatment of Glaucoma and Ocular Hypertension

edited by Ahnul Ha

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2163 | Submission Open

Keywords: glaucoma; ocular hypertension; intraocular pressure (IOP); minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI); neuroprotection; meta-analysis

(This special issue belongs to the Section Ophthalmology)

Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 20 Jan 2026 | 2 articles | Viewed by 2039 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Emerging Treatment Options in Inflammatory Bowel Disease

edited by

Sandro Ardizzone

and Roberta Maselli

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2022 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; small molecule therapies; personalized medicine; therapeutic drug monitoring; immunology; gut microbiome; clinical practice; endoscopic mucosal resection (EMR); endoscopic submucosal dissection (ESD); endoscopic balloon dilation and endoscopic stent placement; chromoendoscopy; confocal laser endomicroscopy; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sarcopenia Across the Lifespan: Risk Factors, Mechanisms, and Management in Aging and Disease

edited by

Juan Mielgo-Ayuso

and

Natalia Busto

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1998 | Submission Open

Keywords: sarcopenia; aging; chronic disease; risk factors; muscle physiology; prevention; nutrition; exercise; treatment strategies

(This special issue belongs to the Section Orthopedics)

Endometriosis: Diagnosis and Treatment

edited by

Camran R. Nezhat

and

Ceana Nezhat

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1487 | Submission Open

Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis; adenomyosis; and adenomyoma care; multidisciplinary care; personalized medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 451-500 on page 10 of 31.

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