Iron Deficiency in Patients with Heart Failure: New Advances in Translational and Clinical Research

 Dear Colleagues,

Heart failure is a devastating syndrome with a very negative impact on mortality, morbidity, and health-related quality of life in patients with this diagnosis. Heart failure also represents a challenge to healthcare systems due to its growing prevalence and the rising medical resource use and expenditure associated with this syndrome. Comorbidities, and particularly iron deficiency, have been identified as a factor that may partially explain the occurrence of major adverse events and limitations in patient-reported outcomes in the setting of heart failure. Recent advances in research have settled the basis of the treatment of iron deficiency and helped to understand the pathophysiological pathways linking iron deficiency and heart failure. However, there are still many gaps of knowledge regarding the complex interplay between iron deficiency and heart failure. In summary, new advances in translational and clinical research will broaden the knowledge of iron deficiency in heart failure and will increase awareness of clinicians about this comorbidity. All these will finally translate into benefits for heart failure patients.

Dr. Josep Comín-Colet
Guest Editor

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