New Targets in Cardiovascular Disease: Towards Innovative Pharmacological and Nutritional Approaches

Dear Colleagues,

In recent years, continuous advances in science and the development of new techniques have allowed one to document the complex network of factors that interact cumulatively to trigger the onset of the atherosclerotic phenomenon and its progression. In particular, the development of new techniques (e.g., omics approaches) is helping to unravel different mechanism related to CVD development (e.g., oxidative stress, inflammation, and fatty acid oxidation) beyond traditional risk factors. This is key to developing innovative approaches in CVD prevention (including novel laboratory technologies to explore metabolic alterations and molecular studies of predisposition genes) and treatment (e.g., nutraceutical supplementations). Since the pivotal observation by Ancel Keys’s (almost 60 years ago), the link between cardiovascular disease (CVD) and nutrition has been increasingly recognized. Food and nutraceuticals behave similarly, and efforts are being made to set up healthy balanced diets to prevent oxidative stress and, in turn, CVD. To single out appropriate targets to prevent and treat CVD by combining newer pharmacological and nutritional approaches, the most advanced research information in the area should be gathered and related/translated to practical (clinical and pathophysiological) questions. This is the aim of the present Special Issue.

Dr. Alessandro Di Minno
Dr Benedetta Porro
Dr. Felice Amato
Guest Editors

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