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Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine".

Deadline for manuscript submissions: 10 June 2026 | Viewed by 784

Special Issue Editors


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Guest Editor
Oral and Maxillo-Facial Unit, AUSL Bologna Bellaria-Maggiore Hospital, Bologna, Italy
Interests: head and neck reconstruction; facial fractures minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillofacial trauma and deformities

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Guest Editor
Oral and Maxillo-Facial Unit, Policlinico Umberto I, Roma, Italy
Interests: head and neck reconstruction; facial fractures minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillofacial trauma and deformities
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Oral and Maxillo-Facial Unit, Ospedale San Martino, Genova, Italy
Interests: head and neck reconstruction; facial fractures minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillofacial trauma and deformities

Special Issue Information

Dear Colleagues,

Facial fractures and deformities encompass alterations of function and esthetics, particularly in serious cases. New technologies have changed our approach toward the treatment of these kinds of facial abnormalities.

This Special Issue of the Journal of Clinical Medicine, focused on the “Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities”, aims to highlight the latest research, innovative treatment strategies, and multidisciplinary approaches in our field.

With this Special Issue, we hope to foster a deeper understanding of these complex conditions and promote collaboration among researchers and clinicians to underline the best management options reported in the literature.

We invite you to submit original research articles and reviews that align with, but are not limited to, the following themes:

  • Current treatments in trauma and deformity cases of the head and neck region;
  • Insights into the management of reconstructive strategies;
  • Innovations, particularly regarding minimally invasive treatments;
  • New technologies focused on pre-surgical planning and reconstructive planning;
  • Bioengineering in facial treatments and reconstruction;
  • The impact of lifestyle modifications;
  • Future directions in our field.

I look forward to receiving your contributions.

Dr. Gian Marco Prucher
Prof. Dr. Andrea Cassoni
Dr. Francesco Arcuri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck reconstruction
  • facial fractures
  • minimally invasive treatments
  • facial reconstruction
  • bioengineering in head and neck disorders
  • CAD/CAM in maxillo facial trauma and deformities

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Published Papers (2 papers)

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Research

8 pages, 892 KB  
Article
Reconstruction of Surgical Defects of the Oral Cavity with Bilayer Dermal Matrix: Our Experience
by Andrea Ferri, Mara David, Giulia Salti, Giovanni Lilloni, Bernardo Bianchi and Silvano Ferrari
J. Clin. Med. 2025, 14(23), 8534; https://doi.org/10.3390/jcm14238534 - 1 Dec 2025
Viewed by 158
Abstract
Purpose: Reconstructive options for mucosal defects of the oral cavity resulting from the resection of tumors include primary closure, mucosal and split thickness skin grafts, pedicle flaps, and microvascular free flaps. Lately the use of an acellular dermal bilayer matrix has been introduced [...] Read more.
Purpose: Reconstructive options for mucosal defects of the oral cavity resulting from the resection of tumors include primary closure, mucosal and split thickness skin grafts, pedicle flaps, and microvascular free flaps. Lately the use of an acellular dermal bilayer matrix has been introduced for the reconstruction of superficial mucosal defects of the oral cavity. Methods: Twenty-one patients treated for SCC of the oral cavity with intraoral resection and simultaneous reconstruction using a bilayer dermal matrix between 1 January 2020 and 31 December 2024 with at least 6 months of follow-up were retrospectively considered. Data were collected regarding the site of the lesion, the initial TNM staging, the size of the surgical defect, the timing of silicone sheet removal, the complications and the long-term outcomes. Results: Tumor site included the tongue in 16 cases, the hard palate in 1 case, the cheek in 2 cases, the floor of the mouth in 1 patient, and the inferior lip in 1 patient. Re-epithelialization was achieved in all cases within 21 days. No major complication was observed. Conclusions: Bilayer dermal matrix demonstrated to be an excellent option for small and superficial oral cavity reconstruction if proper indications are followed. Full article
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13 pages, 4377 KB  
Article
A Reproducible 3D Classification of Orbital Morphology Derived from CBCT and FBCT Segmentation
by Natalia Bielecka-Kowalska, Bartosz Bielecki-Kowalski and Marcin Kozakiewicz
J. Clin. Med. 2025, 14(21), 7836; https://doi.org/10.3390/jcm14217836 - 4 Nov 2025
Viewed by 325
Abstract
Background: Accurate reconstruction of the orbit after trauma or oncological resection requires reliable anatomical references. In unilateral cases, the contralateral orbit can guide repair, but bilateral injuries or pathologies remove this option. To address this problem, we developed a new morphological classification [...] Read more.
Background: Accurate reconstruction of the orbit after trauma or oncological resection requires reliable anatomical references. In unilateral cases, the contralateral orbit can guide repair, but bilateral injuries or pathologies remove this option. To address this problem, we developed a new morphological classification of orbits based on three linear dimensions. Methods: A total of 499 orbits from patients of Caucasian descent (age 8–88 years) were analyzed using three-dimensional models generated from cone-beam and fan-beam CT scans. Orbital depth (D), height (H), and width (W) were measured, and proportional indices were calculated. K-means clustering (k = 3) identified recurring morphotypes, validated by linear discriminant analysis (LDA) and supported by ANOVA, Kruskal–Wallis, and correlation tests (age and sex). Results: Three morphotypes were identified: Tall & Broad (type A, 33.5%), Deep & Broad (type B, 30.2%), and Compact (type C, 36.2%). All dimensions differed significantly between groups (ANOVA, p < 1 × 10−16; η2 = 0.40–0.51). Male orbits were significantly deeper and wider than female ones (p < 0.001). LDA demonstrated excellent separation with 97.5% accuracy. A simplified decision algorithm achieved 82.1% classification accuracy. In situations where only orbital depth could be measured, an alternative cut-off-based method reached 61.5% accuracy, with type B and C better distinguished than type A. Conclusions: The proposed classification provides a reproducible framework for describing orbital morphology. It may serve as a reference in cases where local anatomy is disrupted or the contralateral orbit is unavailable. Even millimeter-scale differences in orbital dimensions may correspond to clinically relevant changes in orbital volume and globe position, underlining the potential usefulness of this system in surgical planning. Full article
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