Special Issue "Current Advances on Non-Melanoma Skin Cancer"
Deadline for manuscript submissions: 31 August 2020.
2. Department of Physiology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: in vivo reflectance confocal microscopy; dermato-oncology; inflammatory skin diseases; neurogenic inflammation; neuroendocrinology of the skin
Non‑melanoma skin cancer (NMSC) comprises basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and several rare skin tumors and is the most common malignancy affecting humans worldwide. It accounts for the vast majority of skin cancers and a large percentage of all malignant tumors. Despite the growing public awareness and scientific interest regarding the risk of skin cancer, the incidence of NMSC is still rapidly increasing. Even if most NMSCs are associated with a less aggressive behavior, they can still be locally invasive and may produce extensive destruction of neighboring structures, inducing significant morbidity. Moreover, different types or subtypes of NMSCs are associated with frequent recurrence and may carry a significant metastatic potential. As a direct consequence, NMSC has become a major burden on healthcare systems with a significant socio‑economic impact.
Hence, there is no doubt as to why these keratinocyte-derived tumors are in the spotlight of scientific interest for both fundamental research and clinical practice, and this Special Issue aims to bring together the most recent and relevant scientific research on NMSC. Studies regarding the complex inherited and environmental factors that can trigger tumor initiation and progression may offer a new perspective on skin cancer prevention. Investigation of new markers of skin carcinogenesis may contribute to the development of novel diagnostic, staging, and prognosis strategies for skin cancer and could lead to the design of more sophisticated and individually tailored treatment protocols. Improvements related to non-invasive or minimally invasive diagnostic tools and treatment methods may ameliorate the discomfort of patients while also reducing the costs associated with therapy. Moreover, the development of new techniques for early diagnosis of NMSCs could reduce morbidity, ensuring more efficient treatment with better aesthetic and functional results.
Dr. Constantin Caruntu
Manuscript Submission Information
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- non-melanoma skin cancer
- basal cell carcinoma
- squamous cell carcinoma
- early diagnosis
- new technologies