Clinical Advances in Spine Disorders

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 2782

Special Issue Editors


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Guest Editor
Neurosurgery Unit, Cardinale G. Panico Hospital, 73039 Tricase, Italy
Interests: spinal surgery; spinal cord injury; spine surgery; microneurosurgery; neuro-oncology; glioma; traumatic brain injury; neuroanatomy; brain tumors; intervertebral disk degeneration

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Guest Editor
Department of Neuroscience, Mental Health and Sense Organs (NESMOS), Sant’Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy
Interests: spine surgery; spinal surgery; spinal cord injury; microneurosurgery; neuroanatomy; brain injury; traumatic brain injury; glioma; spine
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Special Issue Information

Dear Colleagues,

Clinical advances and surgical techniques for the treatment of spine disorders have been effective in minimizing invasiveness and reducing complications. However, there is always a need for improvements in patient outcomes with new understandings of the latest developments in lumbar spine surgery. In this Special Issue "Clinical Advances in Spine Disorders" of the Journal of Clinical Medicine, we are interested in providing a comprehensive overview of the latest evolution of emerging conservative treatment and surgical techniques, with a focus on minimally invasive surgery and the use of robotics and navigation systems.

We welcome authors to submit their papers in this Special Issue focusing on the newest clinical advances in spine disorders. We hope that it will stimulate interest regarding the unsolved challenges in spine surgery.

Dr. Sokol Trungu
Dr. Luca Ricciardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • spine disorders
  • lumbar spine surgery
  • minimally invasive surgery
  • spine surgery
  • microneurosurgery

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Published Papers (2 papers)

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8 pages, 409 KiB  
Article
Influence of a Lordotic Cage Profile on Global and Segmental Lordosis in the Context of Lumbar TLIF Surgeries: A Retrospective Radiological Analysis
by Steffen Schulz, Peter Fennema, Ali Darwich, Frederic Bludau and Marcus Rickert
J. Clin. Med. 2024, 13(23), 7012; https://doi.org/10.3390/jcm13237012 - 21 Nov 2024
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Abstract
Background/Objectives: Cage implantation decompresses neural elements, stabilizes segments, and promotes fusion, with sagittal balance influenced by cage size, geometry, and position. This retrospective study compared the effects of lumbar interbody cages with 10° and 15° lordotic angles on global and segmental lordosis in [...] Read more.
Background/Objectives: Cage implantation decompresses neural elements, stabilizes segments, and promotes fusion, with sagittal balance influenced by cage size, geometry, and position. This retrospective study compared the effects of lumbar interbody cages with 10° and 15° lordotic angles on global and segmental lordosis in patients undergoing transforaminal lumbar interbody fusion (TLIF). Methods: Data from 215 patients who underwent 259 TLIF procedures between 2018 and 2022 were analyzed. All the surgeries were performed by a single senior orthopedic spine surgeon, and cages were selected by the surgeon based on patients’ clinical and anatomical factors. Radiographic assessments included measurements of global and segmental lordosis. Results: Patients who received 15° cages demonstrated significantly greater segmental lordosis compared to those who received 10° cages in both bisegmental and monosegmental procedures (p < 0.001). While the global lordosis in the 10°-cage group remained unchanged postoperatively (p = 0.687), bisegmental procedures showed a small but statistically significant increase (p = 0.035). Moreover, global lordosis did not significantly differ between the 10°- and 15°-cage groups. Conclusions: Cage geometry significantly influenced segmental lordosis, with 15° cages achieving overall more superior radiographic results compared to 10° cages. However, global lordosis was unaffected by cage angle, thereby highlighting the multifaceted nature of factors that influence overall spinal alignment. These findings provide valuable insights into lumbar spine surgery, thus emphasizing the need for comprehensive preoperative planning and consideration of individual patient characteristics. Full article
(This article belongs to the Special Issue Clinical Advances in Spine Disorders)
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28 pages, 914 KiB  
Systematic Review
Prognostic Factors in Patients Undergoing Physiotherapy for Chronic Low Back Pain: A Level I Systematic Review
by Alice Baroncini, Nicola Maffulli, Marco Pilone, Gennaro Pipino, Michael Kurt Memminger, Gaetano Pappalardo and Filippo Migliorini
J. Clin. Med. 2024, 13(22), 6864; https://doi.org/10.3390/jcm13226864 - 14 Nov 2024
Cited by 5 | Viewed by 1660
Abstract
Background: Low back pain is common. For patients with mechanic or non-specific chronic LBP (cLBP), the current guidelines suggest conservative, nonpharmacologic treatment as a first-line treatment. Among the available strategies, physiotherapy represents a common option offered to patients presenting with cLBP. The [...] Read more.
Background: Low back pain is common. For patients with mechanic or non-specific chronic LBP (cLBP), the current guidelines suggest conservative, nonpharmacologic treatment as a first-line treatment. Among the available strategies, physiotherapy represents a common option offered to patients presenting with cLBP. The present systematic review investigates the prognostic factors of patients with mechanic or non-specific cLBP undergoing physiotherapy. Methods: In September 2024, the following databases were accessed: PubMed, Web of Science, Google Scholar, and Embase. All the randomised controlled trials (RCTs) which evaluated the efficacy of a physiotherapy programme in patients with LBP were accessed. All studies evaluating non-specific or mechanical LBP were included. Data concerning the following PROMs were collected: the pain scale, Roland Morris Disability Questionnaire (RMQ), and Oswestry Disability Index (ODI). A multiple linear model regression analysis was conducted using the Pearson Product–Moment Correlation Coefficient. Results: Data from 2773 patients were retrieved. The mean length of symptoms before the treatment was 61.2 months. Conclusions: Age and BMI might exert a limited influence on the outcomes of the physiotherapeutic management of cLBP. Pain and disability at baseline might represent important predictors of health-related quality of life at the six-month follow-up. Further studies on a larger population with a longer follow-up are required to validate these results. Full article
(This article belongs to the Special Issue Clinical Advances in Spine Disorders)
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