Development of Nanocomposite Materials for Environmental Remediation and Biomedical Application

A special issue of Inorganics (ISSN 2304-6740). This special issue belongs to the section "Inorganic Materials".

Deadline for manuscript submissions: 15 June 2025 | Viewed by 2924

Special Issue Editors


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Guest Editor
College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China
Interests: catalysis; porous materials; energy conversion; environmental protection
Special Issues, Collections and Topics in MDPI journals
College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China
Interests: photocatalytic; green chemistry; catalytic chemistry

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Guest Editor
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA
Interests: nanoparticle preparation; surface enhanced Raman scattering (SERS); fluorescence spectroscopy

Special Issue Information

Dear Colleagues,

This Special Issue aims to gather the latest advances in nanomaterials and nanocomposites designed for high-performance applications in environmental remediation and biomedicine. We invite submissions of original research articles and reviews covering various aspects such as material synthesis, fabrication, structural characterization, advanced properties, and potential applications. We particularly welcome contributions addressing the following themes:

  1. Techniques for the synthesis and fabrication of nanocomposite materials, including graphene-based nanocomposites, carbon nanotubes (CNTs), multiwall CNTs, Mxene-based nanocomposites, and polymer-based nanocomposites.
  2. Methods for the structural characterization of nanocomposite materials, such as spectroscopic techniques, microscopy, and X-ray diffraction.
  3. Investigation of advanced properties of nanocomposite materials, including mechanical, electrical, optical, and thermal properties.
  4. Applications of nanocomposite materials in environmental remediation, such as in the removal of antibiotics from aqueous systems, disinfection of air and water, marine pollution and biofouling prevention, and soil remediation.
  5. Applications of nanocomposite materials in biomedicine, including drug delivery, malignant tumor treatment, biosensing, and medical imaging.

We encourage submissions that provide insights into the synergistic effects of combining different nanocomponents and their impact on the overall performance of the materials. Contributions addressing sustainable development and the role of nanostructure in composite properties are especially welcome.

We look forward to receiving your contributions.

Prof. Dr. Jianqiang Yu
Dr. Yan Zhang
Dr. Sanjun Fan
Guest Editors

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Keywords

  • nanocomposite materials
  • nanostructured carbon
  • environmental remediation
  • biomedical application

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Published Papers (3 papers)

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Research

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19 pages, 3088 KiB  
Article
A Magnetic Nanocarrier of Ciprofloxacin Used for Restraining the Growth of the Multidrug-Resistant Pseudomonas aeruginosa
by Kleoniki Giannousi, Eleni Zouni, Nikolaos Grigoriadis, Ioannis S. Vizirianakis, Ilias M. Oikonomou, Valeria Nicolosi and Catherine Dendrinou-Samara
Inorganics 2025, 13(2), 58; https://doi.org/10.3390/inorganics13020058 - 16 Feb 2025
Viewed by 544
Abstract
Ciprofloxacin (CPL) is an effective antibiotic against Pseudomonas aeruginosa. However, its use is limited by the emergence of multi-resistant strains. In this study, 8–15 nm manganese ferrite (MnFe2O4) nanoparticles, aminated and/or PEGylated, have been used as drug-delivery systems [...] Read more.
Ciprofloxacin (CPL) is an effective antibiotic against Pseudomonas aeruginosa. However, its use is limited by the emergence of multi-resistant strains. In this study, 8–15 nm manganese ferrite (MnFe2O4) nanoparticles, aminated and/or PEGylated, have been used as drug-delivery systems of CPL. The magnetic nanoparticles (MNPs) were prepared in the presence of the aliphatic amines octadecylamine (ODA), oleylamine (OAm), or PEG8000 to achieve the appropriate surface chemistry for the direct conjugation of CPL and drug loading into the PEG matrix, respectively. The primary MNPs proved to be biocompatible in calf thymus (CT)-DNA interaction studies, with binding constant values Kb in the range of 4.43–6.5 × 104 (g/mL)−1. ODA as a coater gave rise to MnFe2O4 MNPs, with a high percentage of free amines that further allowed for the conjugation of 90.9% CPL, which gradually released via a non-Fickian anomalous transport motif. The 25.1% CPL that loaded in the PEGylated MNPs led to a partial transformation of the nanoflowers into more aggregated forms. The release profile, although steeper, is described by the same model. The isolated magnetic nanocarrier with a high content of CPL was evaluated for its antimicrobial activity against a multi-resistant strain of P. aeruginosa using an automated industrial instrument (BacT/ALERT®3D), and its molecular profile was outlined by studying its interaction with plasmid DNA (pDNA). The prototype use of BacT/ALERT®3D allows for the simultaneous screening of multiple samples, while it foreshadows the transition to a preclinical phase. Full article
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14 pages, 4411 KiB  
Article
Fabrication of Two-Dimensional Bi2MoO6 Nanosheet-Decorated Bi2MoO6/Bi4O5Br2 Type II Heterojunction and the Enhanced Photocatalytic Degradation of Antibiotics
by Fengshu Kang, Gaidong Sheng, Xiaolong Yang and Yan Zhang
Inorganics 2024, 12(11), 289; https://doi.org/10.3390/inorganics12110289 - 4 Nov 2024
Cited by 2 | Viewed by 1134
Abstract
This article successfully synthesized a series of Bi2MoO6/Bi4O5Br2 heterojunctions using a two-step solvothermal method followed by calcination, and the photocatalytic activity by degradation of tetracycline hydrochloride (TC) was investigated. Compared with pure Bi4 [...] Read more.
This article successfully synthesized a series of Bi2MoO6/Bi4O5Br2 heterojunctions using a two-step solvothermal method followed by calcination, and the photocatalytic activity by degradation of tetracycline hydrochloride (TC) was investigated. Compared with pure Bi4O5Br2 and Bi2MoO6, a series of Bi2MoO6/Bi4O5Br2 heterojunctions exhibit higher photocatalytic activity, which can be attributed to the heterostructures with strong interfacial interaction, improving the charge separation. The 2% Bi2MoO6/Bi4O5Br2 heterojunction shows the best photocatalytic activity under visible light irradiation, which is 1.9 times and 1.8 times that of Bi2MoO6 and Bi4O5Br2, respectively. In addition, cyclic experiments have shown that 2% Bi2MoO6/Bi4O5Br2 heterojunction has high stability, with a degradation efficiency only decreasing by 3% after 5 cycles. From the capture agent experiment and ESR test, it can be seen that ·O2 and h+ are the main active species. A possible photocatalytic mechanism of 2% Bi2MoO6/Bi4O5Br2 heterojunction under visible light irradiation was proposed. Full article
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Review

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30 pages, 17823 KiB  
Review
Emerging Piezoelectric Sonosensitizer for ROS-Driven Sonodynamic Cancer Therapy
by Guiyun Wang, Yanxia Qi, Zhuang Liu and Ruowei Wang
Inorganics 2025, 13(3), 71; https://doi.org/10.3390/inorganics13030071 - 26 Feb 2025
Viewed by 614
Abstract
As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound and sonosensitizers. Piezoelectric materials, known for their remarkable capacity of interconversion of mechanical and electrical [...] Read more.
As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, resulting from the interplay between low-intensity ultrasound and sonosensitizers. Piezoelectric materials, known for their remarkable capacity of interconversion of mechanical and electrical energy, have garnered considerable attention in biomedical applications, which can serve as pivotal sonosensitizers in SDT. These materials can generate internal electric fields via ultrasound-induced mechanical deformation, which modulates the alteration of charge carriers, thereby initiating surface redox reactions to generate reactive oxygen species (ROS) and realizing the therapeutic efficacy of SDT. This review provides an in-depth exploration of piezoelectric materials utilized in SDT, with a particular emphasis on recent innovations, elucidation of underlying mechanisms, and optimization strategies for advanced biomedical piezoelectric materials. Furthermore, the incorporation of piezoelectric sonosensitizers with immunotherapy, photodynamic, chemodynamic, and chemotherapy is explored, emphasizing their potential to enhance cancer therapy outcomes. By examining the basic principles of the piezoelectric effect and its contributions to SDT, this review sheds light on the promising applications of piezoelectric materials in oncology. It also highlights future directions for improving these materials and expanding their clinical utility in tumor sonodynamic therapy. Full article
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