International Journal of Molecular Sciences

Hepatopancreatic and Intestine Diseases: From Molecular Basis to Therapy

edited by

and Emma Folch-Puy

submission deadline 20 Jul 2025 | 5 articles | Viewed by 9144 | Submission Open

Keywords: hepatopancreatic diseases; intestine diseases; molecular basis; therapy; pathogenesis; molecular pathways; pharmacological interventions; surgical techniques; immunotherapies; regenerative medicine approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Biomedical and Tissue Engineering Strategies to Cross the Blood–Brain Barrier for Next-Generation Treatments Against Neurodegenerative Diseases

edited by

Manuele Gori

and Livia La Barbera

submission deadline 20 Jul 2025 | 5 articles | Viewed by 9138 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer’ s disease; CNS; blood– brain barrier; drug delivery systems; nanocarriers; nanomedicine; tissue engineering; theranostics

(This special issue belongs to the Section Molecular Neurobiology)

Novel Insight into Epigenomic Studies of Human Disease

edited by

Mitsuko Masutani

and Takashi Ito

submission deadline 20 Jul 2025 | 5 articles | Viewed by 9071 | Submission Open

Keywords: epigenetic regulation; DNA methylation; protein methylation; protein acetylation; histone modification; noncoding RNAs (ncRNAs); post-translational modifications (PTMs); chromatin; human disease

(This special issue belongs to the Section Molecular Genetics and Genomics)

A Molecular Perspective on the Genetics of Kidney Diseases

edited by Joaquim Calado

submission deadline 20 Jul 2025 | 5 articles | Viewed by 9055 | Submission Open

Keywords: kidney; genetics; solute transport; genomics; inflammation; dysmetabolism

(This special issue belongs to the Section Molecular Genetics and Genomics)

Mitochondrial Function in Human Health and Disease: 2nd Edition

edited by

Yumay Chen

submission deadline 20 Jul 2025 | 6 articles | Viewed by 8875 | Submission Open

Keywords: mitochondial genesis and disease; mitochondrial function and aging; mitochondrial dysfunction and cancer; mitochondrial function and apoptosis; mitophage; autophage; mitochondrial AKT TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Biochemistry)

Prostate Cancer: Novel Research and Innovative Therapeutic Strategies

edited by

Giovanni Luca Beretta

submission deadline 20 Jul 2025 | 4 articles | Viewed by 8790 | Submission Open

Keywords: prostate cancer; therapeutic strategy; castration-resistant PCa

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cutting-Edge Research and Applications of Extracellular Microvesicles in Disease Management

edited by María Isabel Torres

submission deadline 20 Jul 2025 | 5 articles | Viewed by 8782 | Submission Open

Keywords: extraccellular microvesicles; exosome; ectosoma; biomarkers; cargoes of extracellular vesicles; therapeutics; diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hormone Signaling in Human Health and Diseases, 2nd Edition

edited by

Antonella Muscella

submission deadline 20 Jul 2025 | 6 articles | Viewed by 8716 | Submission Open

Keywords: hormone; cell receptor; endocrine signaling; cancer; insulin; oestrogen; testosterone; angiotensin; gonadotropin; thyroid hormone

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Role of Proteomics in Human Diseases and Infections

edited by

Mahamud Ur Rashid

and Kevin Coombs

submission deadline 20 Jul 2025 | 5 articles | Viewed by 8697 | Submission Open

Keywords: proteomics; human diseases; infections; biomarkers; therapeutic targets; disease pathogenesis; host– pathogen interactions; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Breakthroughs in Molecular Diagnostic Tools for Human Diseases

edited by

Vittorio Fineschi

and

Aniello Maiese

submission deadline 20 Jul 2025 | 7 articles | Viewed by 8615 | Submission Open

Keywords: molecular pathology; molecular diagnostics; genetics; epigenetics; proteomics; immunohistochemistry; thrombo-embolic disease; sudden cardiac death; molecular pathology of traumatic injuries; hypoxic– ischemic brain damage; experimental models of injury and diseases; targeted therapy of injuries and diseases; drug abuse; histological diagnosis; epigenetics of organs injuries; miRNA and prognosis of diseases; novel approaches and proofs of principle in therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Lung Cancer

edited by

Bassam Redwan

submission deadline 20 Jul 2025 | 3 articles | Viewed by 8559 | Submission Open

Keywords: lung cancer; immunotherapy; molecular diagnostic; next-generation sequencing

(This special issue belongs to the Section Molecular Oncology)

Recent Progress of Opioid Research, 2nd Edition

edited by

Soichiro Ide

and

Kazutaka Ikeda

submission deadline 20 Jul 2025 | 5 articles | Viewed by 8512 | Submission Open

Keywords: opioids; opioid crisis; pain; analgesic; addiction; dependence; stress; reward; opioid peptides; opioid use disorder

(This special issue belongs to the Section Molecular Pharmacology)

Inflammation in Chronic Disease: Molecular Mechanisms and Signaling Pathways

edited by

Nadia Lampiasi

submission deadline 20 Jul 2025 | 4 articles | Viewed by 8344 | Submission Open

Keywords: inflammation; neuroinflammation; immune response; inflammation-associated disease; inflammation mediators (proteins; enzymes; ecc); cytokines; macrophages; mast cells; monocytes; dendritic cells; oxidative stress; signaling pathways

(This special issue belongs to the Section Molecular Immunology)

Dopamine, Histamine, Serotonin—Receptors, Ligands and Their Biological Role in Central Nervous System Diseases, 2nd Edition

edited by

Dorota Łażewska

and

Anna Stasiak

submission deadline 20 Jul 2025 | 4 articles | Viewed by 8307 | Submission Open

Keywords: biogenic amines (histamine; dopamine; serotonin); receptors; ligands; antagonist/inverse agonist; affinity; intrinsic activity; multitarget ligands; molecular modeling; CNS diseases; neurodegeneration; psychiatric disorders; pain; in vitro studies; in silico studies; in vivo studies

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Protein–Ligand Interactions

edited by Dong-Jun Yu

submission deadline 20 Jul 2025 | 4 articles | Viewed by 8256 | Submission Open

Keywords: drug design; binding specificity; molecular docking; ligand screening; structural biology; protein– protein interactions; protein– ligand interactions; protein– lipid complexes; protein– nucleic acid interactions

(This special issue belongs to the Section Macromolecules)

Recent Advances in Molecular Mechanisms Underlying Kidney Diseases: Pathophysiology and Therapeutic Targets, 2nd Edition

edited by

George J. Dugbartey

submission deadline 20 Jul 2025 | 4 articles | Viewed by 8070 | Submission Open

Keywords: kidney diseases; pathophysiology; molecular mechanisms; therapeutic targets; acute kidney injury; chronic kidney disease; polycystic kidney disease; end-stage renal disease; IgA nephropathy; diabetic nephropathy; hypertensive nephropathy; renal cancer; kidney infarction; kidney infection; kidney failure; kidney stones; renal tubular acidosis; renal artery stenosis; acute tubular necrosis; glomerulopathy; interstitial nephritis; nephrotic syndrome; simple kidney cyst

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Epigenetic Influences on Personality Traits and Athletic Performance

edited by

Kinga Huminska-Lisowska

submission deadline 20 Jul 2025 | 1 articles | Viewed by 7928 | Submission Open

Keywords: genetics; epigenetics; personality traits; athletic performance; polymorphisms; microbiome; neurotransmitters; molecular mechanisms; metabolic health; injury susceptibility

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research and Cellular Biology of Breast Cancer

edited by

Andrea Nicolini

and

Cristian Scatena

submission deadline 20 Jul 2025 | 8 articles | Viewed by 7861 | Submission Open

Keywords: molecular mechanisms of tumor growth and diffusion; cancer cell biology; biology of tumor micro-environmental cells; MDR; hormone dependency; HER2 positive breast cancer; TNBC; genetic and epigenetic alterations; pro-tumor and anti-tumor immune responses; conventional and biological therapies; blood and tissue biomarkers

(This special issue belongs to the Section Molecular Oncology)

Challenges and Innovation in Neurodegenerative Diseases, 2nd Edition

edited by

King-Ho Cheung

submission deadline 20 Jul 2025 | 6 articles | Viewed by 7860 | Submission Open

Keywords: neurodegenerative diseases; pathogenesis; biomarkers; disease model; natural product; new drug discovery; therapy; machine learning; stem cell therapy

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Metabolisms in Cartilage Health and Diseases: 3rd Edition

edited by

Masaharu Takigawa

submission deadline 20 Jul 2025 | 5 articles | Viewed by 7807 | Submission Open

Keywords: cartilage; chondrocytes; growth; regeneration; endochondral ossification; arthritis; joint; growth factors; mechanical stress; nutrition

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Chimeric Antigen Receptors Against Cancers and Autoimmune Diseases

edited by

Niels Schaft

submission deadline 20 Jul 2025 | 3 articles | Viewed by 7791 | Submission Open

Keywords: chimeric antigen receptor (CAR); cancer; autoimmune disease; solid tumor; effector cell; CAR format; CAR transfer; tumor microenvironment; targeted antigen

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms and Signalling Pathways in Cardiovascular Pathophysiology

edited by Ernesto Alejandro Aiello

submission deadline 20 Jul 2025 | 5 articles | Viewed by 7623 | Submission Open

Keywords: heart; vascular; signaling; cardiovascular disease; mechanism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Toll-Like Receptors (TLRs) in Infection and Inflammation: Third Edition

edited by

Ralf Kircheis

and

Oliver Planz

submission deadline 20 Jul 2025 | 6 articles | Viewed by 7516 | Submission Open

Keywords: toll-like receptors (TLR); pathogen associated molecular patterns (PAMPs); sepsis; bacterial infections; viral infections; Myd88; TRIF; NF-kappaB; COVID-19; coagulopathies

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms Underlying Vulnerability to Stress-Related Disorders

edited by Marta Pardo

submission deadline 20 Jul 2025 | 3 articles | Viewed by 7211 | Submission Open

Keywords: stress-related disorders; post-traumatic stress disorder; molecular mechanisms; pharmacological targets

(This special issue belongs to the Section Molecular Neurobiology)

Genomic Research of Rare Diseases

edited by Shira Rockowitz and Piotr Sliz

submission deadline 20 Jul 2025 | 7 articles | Viewed by 7097 | Submission Open

Keywords: rare disease ontology; variants of uncertain significance; candidate genes; whole genome sequencing; long read whole genome sequencing; machine learning; multi-omics

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Advances in Medical Microbiology

edited by

Alberto Rizzo

submission deadline 20 Jul 2025 | 4 articles | Viewed by 7094 | Submission Open

Keywords: clinical microbiology; clinical virology; SARS-CoV-2; HPV; sexually transmitted infections; respiratory viruses; emerging pathogens; opportunistic infections

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms and Therapy of Cardiomyopathy

edited by

Maicon Landim-Vieira

submission deadline 20 Jul 2025 | 3 articles | Viewed by 6949 | Submission Open

Keywords: cardiomyopathy; nutrition; exercise; pharmacology; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Animal Research Model for Neurological Diseases, 2nd Edition

edited by

Giuseppe Montalbano

and

Sepand Rastegar

submission deadline 20 Jul 2025 | 3 articles | Viewed by 6916 | Submission Open

Keywords: experimental models; mouse; rat; zebrafish; neurological disease; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; neuroregeneration

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Genitourinary Cancers

edited by

Sabrina Bossio

and

Anna Perri

submission deadline 20 Jul 2025 | 2 articles | Viewed by 6755 | Submission Open

Keywords: genitourinary cancer; molecular markers; oxi-inflammation; tumor microenvironmental; natural products

(This special issue belongs to the Section Molecular Oncology)

Role of RNA Decay in Bacterial Gene Regulation

edited by Sue Lin-Chao and

Vladimir Kaberdin

submission deadline 20 Jul 2025 | 5 articles | Viewed by 6724 | Submission Open

Keywords: RNA stabilizers; RNA decay; RNA turnover; small regulatory RNAs; post-transcriptional control

(This special issue belongs to the Section Molecular Microbiology)

Host-Pathogen Interaction, 6th Edition

edited by

Andreas Burkovski

submission deadline 20 Jul 2025 | 3 articles | Viewed by 6708 | Submission Open

Keywords: microorganisms; pathogen; bacteria; yeasts; protozoa; host organisms

(This special issue belongs to the Section Molecular Microbiology)

Microplastics and Nanoplastics Ecotoxicological Effects in Seawater and Freshwater Organisms

edited by

Carlos García

submission deadline 20 Jul 2025 | 3 articles | Viewed by 6707 | Submission Open

Keywords: microplastics; exposure; aquatic organisms; sorption; degradation; bioaccumulation; biomagnification; migration; bioindicators; marine toxins

(This special issue belongs to the Section Molecular Toxicology)

New Insights into Aquaporins: 2nd Edition

edited by

Graça Soveral

and

Inês Vieira Da Silva

submission deadline 20 Jul 2025 | 5 articles | Viewed by 6661 | Submission Open

Keywords: aquaporin; membrane channel; regulation; pathophysiology; drug target

(This special issue belongs to the Section Molecular Biology)

Lung Diseases Molecular Pathogenesis and Therapy

edited by

Kazufumi Nakamura

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6618 | Submission Open

Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insights into Gene Expression Regulation in the Next-Generation Sequencing (NGS) Era

edited by

Maria Samara

submission deadline 20 Jul 2025 | 6 articles | Viewed by 6598 | Submission Open

Keywords: alternative splicing; DNA methylation; histone modification; RNA sequencing; epigenome; metagenomics; single-cell sequencing; spatial sequencing; microenvironment; microbiome profile

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Research on Nucleic Acids: Therapeutic Potential and Applications, 2nd Edition

edited by

Veronica Esposito

and

Antonella Virgilio

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6477 | Submission Open

Keywords: aptamer; decoy; DNAzyme; ribozyme; siRNA; miRNA; antisense oligonucleotide; antigene strategy; G-quadruplex; triplex

(This special issue belongs to the Section Biochemistry)

Genetic and Epigenetic Regulation of Reproduction

edited by

Dorota Juchno

and

Olga Jablonska

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6451 | Submission Open

Keywords: gene expression; gene mapping; germ cells; epigenetic factors; DNA methylation; histone modification; fertility; molecular diagnostics; next generation sequencing; prenatal diagnosis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Diagnostics and Therapeutics of Epileptic Neurodevelopment

edited by Christalena Sofocleous

submission deadline 20 Jul 2025 | 2 articles | Viewed by 6448 | Submission Open

Keywords: epileptic neurodevelopment; molecular diagnostics; next-generation sequencing; genetics; epigenetics; pathogenic/likely pathogenic variants; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Targeted Treatments in Cancer: 2nd Edition

edited by

Kazuko Kaneda-Nakashima

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6442 | Submission Open

Keywords: TAT (targeting alpha therapy); nuclear medicine; cancer treatment; imaging; radioisotope (RI); surface marker; TRT (targeted radioisotope therapy)

(This special issue belongs to the Section Molecular Oncology)

Bioinformatics Study in Human Diseases: Integration of Omics Data for Personalized Medicine (Second Edition)

edited by

Hung-Yu Lin

and

Pei-Yi Chu

submission deadline 20 Jul 2025 | 6 articles | Viewed by 6370 | Submission Open

Keywords: cancers; ageing-related diseases; bioinformatics; multi-omics; pharmacogenetics; deep learning; evolutionary learning; diagnosis; prognosis; companion biomarker; drug screening; mechanism dissection

(This special issue belongs to the Section Molecular Informatics)

Recent Advances in Molecular Targets for Treatment and Drug Delivery in Tumors

edited by

Emily Capone

submission deadline 20 Jul 2025 | 6 articles | Viewed by 6318 | Submission Open

Keywords: targeted therapy; tumor; molecular target; drug delivery; drug design

(This special issue belongs to the Section Molecular Oncology)

Understanding Reproductive Health and Infertility: Molecular and Genetic Insights

edited by

Jan Tesarik

submission deadline 20 Jul 2025 | 6 articles | Viewed by 6187 | Submission Open

Keywords: sperm quality; oocyte quality; uterine receptivity

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Macromolecules Structure, Function, and Regulation: 2nd Edition

edited by

Zhiwei Yang

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5992 | Submission Open

Keywords: conformational dynamics; structural modeling; docking; molecular recognition; regulation mechanism; rational design; molecular dynamic simulation

(This special issue belongs to the Section Molecular Biophysics)

Recent Research on Hypertension and Related Complications

edited by

Marijn Speeckaert

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5803 | Submission Open

Keywords: arterial hypertension; cardiovascular disease; pathophysiology; molecular mechanisms; complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances and Perspectives in Limbal Epithelial Stem Cells and Their Niche

edited by

Naresh Polisetti

and Ursula Schlötzer-Schrehardt

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5755 | Submission Open

Keywords: limbal epithelial stem cells; ocular surface; limbal stem cell niche; homeostasis; limbal mesenchymal stromal cells; regeneration; limbal melanocytes; extracellular matrix components

(This special issue belongs to the Section Biochemistry)

Application of Biomolecular Materials in Tissue Engineering

edited by

István Hornyák

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5754 | Submission Open

Keywords: biomolecular materials; tissue engineering; material science; in vitro and in vivo biodegradation; cell culture; tissue regeneration; cell scaffold; biocompatible materials

(This special issue belongs to the Section Materials Science)

Abiotic Stresses in Plants: From Molecules to Environment—2nd Edition

edited by

Martin Bartas

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5589 | Submission Open

Keywords: stress signaling; abiotic stress; oxidative stress; genotoxic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Density Functional Theory and Related Methods for Molecular Computational Chemistry

edited by Paolo Umari

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5582 | Submission Open

Keywords: density functional theory; quantum chemistry; algorithms; quantum computing; high-performance computing; machine learning; many-body perturbations theory; quantum Monte Carlo

(This special issue belongs to the Section Molecular Informatics)

The Role of RNAs in Cancers: Recent Advances

edited by Roman Beňačka

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5483 | Submission Open

Keywords: cancer cells; carcinogenesis; mRNAs; ncRNAs; lncRNAs; miRNAs; circRNAs; piRNAs; RNA-based diagnostics; RNA-based therapy

(This special issue belongs to the Section Molecular Oncology)

Chromatin Remodelers as Players and Drivers in Pathological States

edited by Matteo De March

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5468 | Submission Open

Keywords: protein structure/function; chromatin remodelers; DNA repair; oncogene/oncosuppressor; cancer

(This special issue belongs to the Section Molecular Biology)

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