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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Insulin Resistance Research: 2nd Edition

edited by

Byungyong Ahn

submission deadline 20 Jun 2025 | Viewed by 419 | Submission Open

Keywords: insulin resistance; obesity; metabolic diseases; diabetes; metabolism; inflammation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Environmental Heavy Metals with Their Benefits and Risks for Human Health

edited by

Rolf Teschke

submission deadline 20 Jun 2025 | Viewed by 416 | Submission Open

Keywords: heavy metals; metal compound; iron; copper; cadmium; arsenic; oxidative stress; cell death; toxicology; Wilson disease; hemochromatosis

(This special issue belongs to the Section Molecular Toxicology)

Molecular Insights into Lipodystrophy

edited by

Sofía Sánchez-Iglesias

and

David Araújo-Vilar

submission deadline 20 Jun 2025 | Viewed by 412 | Submission Open

Keywords: lipodystrophy; adipogenesis; animal models; lipid metabolism; therapeutic targets; insulin signaling pathways; adipose tissue

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Monocytes and Their Derivatives: Bridging Vascular and Neurodegenerative Pathology

edited by

Majid Ghareghani

submission deadline 20 Jun 2025 | Viewed by 391 | Submission Open

Keywords: monocytes; innate immune cells; hematopoietic stem cells; differentiation pathways; neurodegenerative diseases; cardiovascular diseases; macrophages; vascular health; pathological processes; therapeutic targeting

(This special issue belongs to the Section Molecular Immunology)

The Impact of High-Value Compounds from Agri-Food and Waste Sources on Cellular Metabolism

edited by

Anna Spagnoletta

Salvatore Nesci

and

Francesca Oppedisano

submission deadline 20 Jun 2025 | Viewed by 390 | Submission Open

Keywords: phytochemicals; agri-food waste; nutraceutical; cell metabolism; mitochondria; antioxidants; ROS; anti-cancer

(This special issue belongs to the Section Biochemistry)

Epilepsy: From Molecular Basis to Therapy, 2nd Edition

edited by

Henry Hing Cheong Lee

submission deadline 20 Jun 2025 | Viewed by 386 | Submission Open

Keywords: genetic epilepsy; post-traumatic epilepsy; neurodevelopmental disorder; glutamate; GABA; ionic homeostasis; disease-modifying therapy; in vitro; in vivo; animal model; gene replacement therapy; gene editing; protein misfolding; small molecule; pharmacokinetics; pharmacodynamics; translational research; biomarker; clinical trial

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pancreatic Disease: From Molecular Basis to Novel Therapies—2nd Edition

edited by

Agnieszka B. Bialkowska

submission deadline 20 Jun 2025 | Viewed by 372 | Submission Open

Keywords: pancreatitis; acinar-to-ductal neoplasia; early pancreatic neoplasia; fibroinflammatory disease; pancreatic cancer; diabetes Mellitus

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Novel Therapeutic Interventions and Drug Targets for Treatment of Cancer

edited by Adilson Kleber Ferreira

submission deadline 20 Jun 2025 | Viewed by 370 | Submission Open

Keywords: drug targets; innovative immunology prognostic; potential markers; gene editing; personalized medicinal methods; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Metal-Based Compounds: Molecular Mechanisms of Pharmacological Action and Toxicity

edited by

Danijela Z. Krstić

submission deadline 20 Jun 2025 | Viewed by 369 | Submission Open

Keywords: metal elements and ions; metal complexes; metal nanoclusters; pharmacology andpharmacokinetics; in vitro toxicity; in vivo toxicity; toxicity biomarkers; enzymes as pharmacological and toxicity targets; toxicity mechanisms; metallodrugs

(This special issue belongs to the Section Molecular Toxicology)

Reaction Kinetics in Bioinorganic Systems

edited by Łukasz Orzeł and Maria Oszajca

submission deadline 20 Jun 2025 | Viewed by 368 | Submission Open

Keywords: reaction mechanisms; kinetics; biologically active metal complexes; metalloproteins; reactive oxygen; nitrogen and sulfur species; biocatalysis; inorganic chemotherapy and phototherapy

(This special issue belongs to the Section Biochemistry)

Hormone Receptors in Cancer

edited by Rajeshwar R. Tekmal

submission deadline 20 Jun 2025 | Viewed by 367 | Submission Open

Keywords: hormone recptors; hormone-mediated therapies; agonists and antgonists of hormone ligands; coactivators; corepressors

(This special issue belongs to the Section Molecular Oncology)

Role of Cancer Stem Cell Regulatory Pathways in Immune Evasion and Drug Resistance

edited by

Pritam Sadhukhan

submission deadline 20 Jun 2025 | Viewed by 366 | Submission Open

Keywords: cancer immunology; cancer stem cells; cancer metabolism; cancer immunotherapy; biomarkers; drug targets; drug resistance

(This special issue belongs to the Section Molecular Oncology)

Treatment Resistance and Current Advances in Cancer Immunotherapy

edited by

Silvio Naviglio

and

Luigi Sapio

submission deadline 20 Jun 2025 | Viewed by 364 | Submission Open

Keywords: immunotherapy; immune checkpoint inhibitors; predictive/prognostic markers; immunotherapy resistance; immune-related adverse events; multiomics analysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Skeletal Muscle Metabolism and Diseases

edited by Shen-Liang Chen

submission deadline 20 Jun 2025 | Viewed by 359 | Submission Open

Keywords: muscle; metabolism; mitochondria; peroxisome; stem cell; cahcexia

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Autophagy and Programmed Cell Death in Plants and Algae

edited by

Sławomir Borek

submission deadline 20 Jun 2025 | Viewed by 358 | Submission Open

Keywords: algal autophagy and PCD; autophagy-related (Atg) genes and proteins; biotic and abiotic stresses; caspase-like proteases; crop plant improvement; macro-; micro-; and mega-autophagy; metacaspases; selective autophagy; signaling; vacuolar processing enzymes (VPEs)

(This special issue belongs to the Section Molecular Plant Sciences)

Engineered Probiotics in the Treatment of Inflammatory Bowel Disease, Cancer, Infections, and Metabolic Disorders

edited by

Yash Gupta

and

Oliana Carnevali

submission deadline 20 Jun 2025 | Viewed by 353 | Submission Open

Keywords: CRISPR; GMO; Lactobacillus; yeast; Bifidobacterium; tight junctions; inflammatory cascade; IBS; Clostridium; Entamoeba; colorectal cancer; pancreatic cancer

(This special issue belongs to the Section Molecular Microbiology)

Interplay Between Coagulation and Inflammation: Molecular Mechanisms, Clinical Implications, and Therapeutic Strategies

edited by

Hemant Giri

submission deadline 20 Jun 2025 | Viewed by 327 | Submission Open

Keywords: coagulation; inflammation; endothelial dysfunction; anticoagulants; inflammation; venous thrombosis; venous thromboembolism; thromboinflammation; coagulation; inflammasomes; neutrophil extracellular traps; platelets; endothelial activation; vascular remodeling

(This special issue belongs to the Section Molecular Biology)

Molecular Linkage Between Trace Elements and Cancer

edited by Daizo Yoshida

submission deadline 20 Jun 2025 | Viewed by 322 | Submission Open

Keywords: cancer; cell signaling; chelation; copper; selenium; trace element; zinc

(This special issue belongs to the Section Molecular Oncology)

Melatonin: Physiological Effects on Health and Diseases

edited by

Jana Tchekalarova

submission deadline 20 Jun 2025 | Viewed by 319 | Submission Open

Keywords: hormone melatonin; oxidative stress; sleep; metabolism; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Dietary Supplements for Erectile Dysfunction (ED)

edited by

Valerio Sanguigni

submission deadline 20 Jun 2025 | Viewed by 315 | Submission Open

Keywords: erectile dysfunction; dietary supplements; sexual disorder; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Signalling Pathways in Metabolic Diseases and Cancers

edited by

Sabrina Bossio

submission deadline 20 Jun 2025 | Viewed by 314 | Submission Open

Keywords: cancer; prostate cancer; molecular signalling pathway; metabolic diseases; diabets; immunotherapy; immunological diseases

(This special issue belongs to the Section Biochemistry)

Physiological and Pathophysiological Aspects of Intracellular and Extracellular Modulator Proteases

edited by

Takuro Miyazaki

submission deadline 20 Jun 2025 | Viewed by 309 | Submission Open

Keywords: a disintegrin and metalloproteinase domain-containing protein; calpain; ectoproteinase; inflammasome; secretase

(This special issue belongs to the Section Molecular Biology)

Endometrial Function in Women with Polycystic Ovary Syndrome: Molecular Data

edited by

Stefano Palomba

submission deadline 20 Jun 2025 | Viewed by 303 | Submission Open

Keywords: endometrium; infertility; polycystic ovary syndrome; PCOS; receptivity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Epigenetics in Autoimmune Diseases

edited by

Tibor A. Rauch

submission deadline 20 Jun 2025 | Viewed by 297 | Submission Open

Keywords: autoimmune disease; DNA methylation; histone modifications; miRNAs; long non-coding RNAs; circRNAs; environmental effects; epigenome-wide analysis; DNMT inhibitors; HDAC inhibitors

(This special issue belongs to the Section Molecular Genetics and Genomics)

MicroRNAs in the Pathophysiology of Chronic Diseases: 2nd Edition

edited by

Mauro Finicelli

and

Tiziana Squillaro

submission deadline 20 Jun 2025 | Viewed by 293 | Submission Open

Keywords: miRNA; lncRNA; circRNA; circulating miRNAs; cancer; cardiovascular disease; neurological diseases; metabolic diseases; immunological diseases; nutraceutical; nanodelivery systems; environmental stressors; unhealthy habits

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Electronic and Steric Effects in Polymerization Mechanisms

edited by Lucia Caporaso,

Fabia Grisi

and Ida Ritacco

submission deadline 20 Jun 2025 | Viewed by 284 | Submission Open

Keywords: homogeneous catalysis; stereospecific polymerization; polymer synthesis; polymer characterization

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Drug Resistance and Biomarkers in Molecular Oncology

edited by Otilia Menyhart

submission deadline 20 Jun 2025 | Viewed by 281 | Submission Open

Keywords: drug resistance; molecular oncology; biomarkers; cancer recurrence; tumor microenvironment; cancer metabolism; cancer stem cells; immune evasion; genetic alterations; epigenetic changes; precision oncology

(This special issue belongs to the Section Molecular Pharmacology)

New Advances in Plant-Fungal Interactions, 2nd Edition

edited by

Zhuo Chen

submission deadline 20 Jun 2025 | Viewed by 277 | Submission Open

Keywords: coding RNAs; non-coding RNAs; axial regulation mechanisms; bidirectional regulation mechanisms; pathogenic mechanisms of pathogens; resistance responses of the host

(This special issue belongs to the Section Molecular Plant Sciences)

Role of Stem Cells in the Cardiovascular System

edited by

William Chilian

and Heather O’Leary

submission deadline 20 Jun 2025 | Viewed by 276 | Submission Open

Keywords: stem cells; single cell genomics; secretome; cardiovascular system; cardiovascular diseases; induced pluripotent stem cells

(This special issue belongs to the Section Molecular Biology)

Advances in Drug Delivery Systems: From Nanoparticles to Precision Medicine

edited by

Satya Prakash

submission deadline 20 Jun 2025 | Viewed by 268 | Submission Open

Keywords: polymer-based nanoparticles; lipid nanoparticles; PLGA and chitosan nano/microparticles for gene therapy; targeted drug delivery; nucleic acid-loaded nanoparticles; siRNA nanoparticles; nanoparticle-mediated mirna delivery; nanoparticles in cancer therapy; nanoparticles in vaccine design; nanoparticle-mediated gene therapy

(This special issue belongs to the Section Molecular Pharmacology)

Study on Organellar Genomes of Vascular Plants

edited by

Monika Szczecińska

submission deadline 20 Jun 2025 | Viewed by 267 | Submission Open

Keywords: mitochondrial DNA (mtDNA); chloroplast DNA (cpDNA); plant evolution; plant organellar genome; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Study on Pathogenesis of Trigeminal Neuralgia

edited by John K. Neubert

submission deadline 20 Jun 2025 | Viewed by 267 | Submission Open

Keywords: trigeminal neuralgia; neuropathic pain; orofacial; neurosurgery; microvascular decompression; fMRI; anti-convulsant; cannabinoid; mGLuR5; TRPV1

(This special issue belongs to the Section Molecular Neurobiology)

Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases, 3rd Edition

edited by

Paramjit S. Tappia

submission deadline 20 Jun 2025 | Viewed by 266 | Submission Open

Keywords: cardiovascular diseases; metabolic diseases; cellular and molecular mechanisms

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research Progress of Optoelectronic Materials and Devices

edited by Moon Jong Han

submission deadline 20 Jun 2025 | Viewed by 265 | Submission Open

Keywords: semiconductors; multifunctionalities; optoelectronics; structure-driven properties; thin films; polymers

(This special issue belongs to the Section Materials Science)

Lymphoma: Molecular Pathologies and Therapeutic Strategies

edited by

Francesco Gaudio

and

Stefano Martinotti

submission deadline 20 Jun 2025 | Viewed by 254 | Submission Open

Keywords: targeted therapy; molecular pathway; Hodgkin’ s lymphoma; non-Hodgkin’ s lymphoma; hematopathology biomarker; new therapeutic approaches

(This special issue belongs to the Section Molecular Oncology)

Isotope Effects in Studies of Chemical and Enzymatic Reactions

edited by

Piotr Paneth

submission deadline 20 Jun 2025 | Viewed by 251 | Submission Open

Keywords: isotope effect; isotopic fractionation; kinetics; enzymatic catalysis; reaction mechanism

(This special issue belongs to the Section Biochemistry)

Future Directions for Mesenchymal Stromal Cells

edited by Fernando A. Fierro

submission deadline 20 Jun 2025 | Viewed by 231 | Submission Open

Keywords: mesenchymal stromal cells; MSC-derived factors; MSC-based therapies; extracellular vesicles

(This special issue belongs to the Section Biochemistry)

Advances in Nano-Drug Delivery Systems

edited by

Mihalj Poŝa

submission deadline 20 Jun 2025 | Viewed by 227 | Submission Open

Keywords: drug nanocarrier; nanomedicine; drug-delivery systems; liposomes; micelles; nanoparticles; cancer treatment

(This special issue belongs to the Section Molecular Nanoscience)

Latest Review Papers in Molecular Biophysics

edited by

Ian A. Nicholls

submission deadline 20 Jun 2025 | Viewed by 222 | Submission Open

Keywords: molecular biophysics; review papers; latest research

(This special issue belongs to the Section Molecular Biophysics)

Updates on Nanophotosensitizers

edited by

Young-Il Jeong

submission deadline 20 Jun 2025 | Viewed by 207 | Submission Open

Keywords: photodynamic therapy; oxidative stress; reactive oxygen species; stimuli-sensitive drug delivery; nanomedicine; nanophotosensitizer; polymer; drug targeting; nano-vaccine; theranosys

(This special issue belongs to the Section Molecular Nanoscience)

Endometriosis: From Molecular Basis to Therapy, 2nd Edition

edited by Grzegorz Polak

submission deadline 20 Jun 2025 | Viewed by 176 | Submission Open

Keywords: endometriosis; endometriosis diagnosis; infertility; novel strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cognitive Aging: Molecular Perspectives

edited by

Igor Y. Iskusnykh

submission deadline 20 Jun 2025 | Viewed by 153 | Submission Open

Keywords: brain; neuron; aging; neurodegeneration; cognitive neuroscience; inflammation; regeneration; behavioral neuroscience; pharmacology; brain disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Diabetes and Its Complications: From Molecular Mechanisms to Novel Therapeutic Approaches—2nd Edition

edited by

Andrea Paola Rojas Gil

submission deadline 20 Jun 2025 | Viewed by 138 | Submission Open

Keywords: diabetes; diabetes complications; environmental factors; endocrine disruptors; nutrition; sleep; therapy; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Insight into Microbial Pathogens in Diseases

edited by

Vanessa Silva

submission deadline 20 Jun 2025 | Viewed by 92 | Submission Open

Keywords: microbial pathogenesis; molecular mechanisms; antimicrobial resistance; biofilm formation; genomics; proteomics; host– pathogen interactions; microbial virulence; disease etiology; omics technologies

(This special issue belongs to the Section Molecular Microbiology)

Application of Biocatalysis in Molecular Sciences

edited by

Roland Wohlgemuth

submission deadline 20 Jun 2025 | Viewed by 73 | Submission Open

Keywords: novel enzymes; enzyme function; enzyme characterization; enzymatic analysis; enzymatic synthesis; multi-step enzymatic reactions; chemoenzymatic synthesis

(This special issue belongs to the Section Biochemistry)

Fundamental and Practical Perspectives in Regenerative Medicine: Proceedings of the VI National Congress of Regenerative Medicine (2024)

edited by

Vsevolod A. Tkachuk

and

Pavel Makarevich

submission deadline 25 Jun 2025 | 2 articles | Viewed by 5059 | Submission Open

Keywords: regenerative medicine; stem cell; gene therapy; cell therapy; tissue engineering

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fat and Obesity: Molecular Mechanisms and Pathogenesis

edited by

Seon-Yong Jeong

submission deadline 25 Jun 2025 | 1 articles | Viewed by 1878 | Submission Open

Keywords: obesity; weight gain; adipogenesis; lipolysis; energy balance; hormones; fat oxidation; nutrition; phytomedicine; drug development; cohort studies; genetics and genomics studies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Probiotics in Health and Disease

edited by

Jasna Novak

submission deadline 25 Jun 2025 | 2 articles | Viewed by 1316 | Submission Open

Keywords: probiotic; microbiota; quality; dysbiosis

(This special issue belongs to the Section Molecular Microbiology)

Urinary Titin: A Novel Biomarker for Muscle Atrophy and Catabolic Conditions

edited by Hiroshi Sakaue

submission deadline 25 Jun 2025 | 1 articles | Viewed by 765 | Submission Open

Keywords: urinary titin; skeletal muscle; muscle atrophy; sarcopenia; biomarker; catabolism; inflammation

(This special issue belongs to the Section Molecular Biology)

Advances in the Physiopathology of Neurodevelopmental Disorders

edited by Antonio Falace

submission deadline 25 Jun 2025 | Viewed by 437 | Submission Open

Keywords: neuronal development; synaptogenesis; developmental and epileptic encephalopathy; epilepsy; biomarkers; neuroimmunology; translational research; cortical malformation; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 801-850 on page 17 of 68.

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