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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Coagulation Factors and Natural Anticoagulants in Health and Disease

edited by

Zsuzsanna Bereczky

submission deadline 31 Jul 2025 | Viewed by 120 | Submission Open

Keywords: coagulation factor; natural anticoagulant; hemostasis; thrombosis; molecular studies; molecular interactions; structure; functional studies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurodegenerative Diseases: From Molecular Mechanisms to Pathophysiology (Second Edition)

edited by

Anne Vejux

submission deadline 31 Jul 2025 | Viewed by 120 | Submission Open

Keywords: neurodegenerative diseases; molecular mechanisms; physiology; cell death; autophagy; oxidative stress; inflammation; genetic factors; diet; cognitive functions; exosomes; blood– brain barrier; immunity

(This special issue belongs to the Section Molecular Neurobiology)

Nanotechnology for Food Science—Innovations and Sustainable Solutions

edited by

Nan Cheng

submission deadline 31 Jul 2025 | Viewed by 117 | Submission Open

Keywords: nanotechnology; nanomaterial synthesis; food safety; food science; nano-engineered food additives; nano-sensors

(This special issue belongs to the Section Molecular Nanoscience)

Peptide and Protein Drugs Against Infectious Diseases and Allergic Diseases

edited by

Xiumin Wang

submission deadline 31 Jul 2025 | Viewed by 117 | Submission Open

Keywords: peptide and protein drugs; infectious diseases; allergic diseases; hormones; antimicrobial peptides; neuropeptides; cell-penetrating peptides; enzyme inhibitors; vaccines; antibodies

(This special issue belongs to the Section Molecular Pharmacology)

Effects of Co-Exposure of Pollutants on Animal Models

edited by

Chiara Maria Motta

submission deadline 31 Jul 2025 | Viewed by 114 | Submission Open

Keywords: environmental health; biological systems; toxic exposure; co-exposure; physiological mechanisms; behavioral responses; gene expression; epigenetic effects; molecular research

(This special issue belongs to the Section Molecular Toxicology)

Natural Compounds in Neurological Diseases

edited by

Ivan Cruz-Chamorro

submission deadline 31 Jul 2025 | Viewed by 113 | Submission Open

Keywords: natural compounds; neuroprotection; neuroinflammation; oxidative stress; mitochondrial dysfunction; autophagy; bioactive molecules (polyphenols; flavonoids; melatonin; etc.); nutraceuticals (bioactive peptides; hydrolysates; etc.); neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Unravelling the Intricate Link Between Microvascular Dysfunction and Cardiovascular Disease

edited by Róbert Pórszász

submission deadline 31 Jul 2025 | Viewed by 112 | Submission Open

Keywords: microvascular dysfunction; cardiovascular pathogenesis; endothelial dysfunction; oxidative stress; nitric oxide bioavailability; VEGF dysregulation; endothelin-1 overactivity; heart failure with preserved ejection fraction (HFpEF); pharmacological interventions; microcirculation-targeted therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Research on the Biological Activities of Natural Components and Their Application

edited by

Željana Fredotović

submission deadline 31 Jul 2025 | Viewed by 111 | Submission Open

Keywords: natural compounds; traditional and medicinal plants; biological activities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Research in Alzheimer’s Disease: Advances and Perspectives

edited by

Silvia Boschi

submission deadline 31 Jul 2025 | Viewed by 109 | Submission Open

Keywords: neuroinflammation; synaptic dysfunction; oxidative stress; neurofibrillary tangles; mitochondrial dysfunction; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Interaction Between Cell and Virus, 3rd Edition

edited by

Masahiro Fujimuro

submission deadline 31 Jul 2025 | Viewed by 109 | Submission Open

Keywords: viral replication; gene expression; lytic infection; viral structure; viral assembly; cell signaling pathway; post-translational modification; immune evasion; viral tumorigenesis; antiviral medication

(This special issue belongs to the Section Molecular Microbiology)

The Application of Large Language Model and Agents in Molecular Medicine and Molecular Biology

edited by

Hao Lin

and Hao Lv

submission deadline 31 Jul 2025 | Viewed by 106 | Submission Open

Keywords: large language models; artificial intelligence; agents; biological data; medical data

(This special issue belongs to the Section Molecular Informatics)

Bioinspired and Emerging Functionalized Nanostructures for Precision Drug Delivery

edited by

Adelina-Gabriela Niculescu

and

Alexandra Catalina Birca

submission deadline 31 Jul 2025 | Viewed by 106 | Submission Open

Keywords: nanostructured materials; nanobiomaterials; nanocomposites; drug delivery systems; targeted therapies; controlled release; responsive functionalities; theranostics; biomedical applications; therapeutic innovations; bioinspired nanostructures; personalized medicine

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms of Plant Adaptation to Stress

edited by Yuanchun Ma

submission deadline 31 Jul 2025 | Viewed by 104 | Submission Open

Keywords: plant; environmental stresses; signaling pathways; stress-responsive genes; transcription factors; phytohormones; crop resilience; breeding; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Synthesis, Biosynthesis and Implications of Chalcones

edited by

Pal Perjesi

submission deadline 31 Jul 2025 | Viewed by 101 | Submission Open

Keywords: chalcones; biosynthesis; biochemistry

(This special issue belongs to the Section Biochemistry)

Progression of Multiple Sclerosis: Environmental Factors, Genetics, Therapeutics and Immunopathogenesis

edited by Alberto Gajofatto

submission deadline 31 Jul 2025 | Viewed by 100 | Submission Open

Keywords: multiple sclerosis; disability progression; neurodegeneration; pathogenesis; immunology; risk factor; environment; genetics; treatment

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Neural Circuits in Behavioral Neuroscience

edited by Matteo Di Segni and Rossella Ventura

submission deadline 31 Jul 2025 | Viewed by 100 | Submission Open

Keywords: behavioral neuroscience; neural circuits; psychopathology; neuroscience; drug addiction; depression; mental illness

(This special issue belongs to the Section Molecular Neurobiology)

Molecular, Cellular and Systems Research on Neuroanatomy, Brain Function and Its Impact on Human Behavior

edited by

Frank Schmitz

submission deadline 31 Jul 2025 | Viewed by 98 | Submission Open

Keywords: central nervous system; neuroanatomy; human behavior; nuclei; neuronal circuits; connectivity channels

(This special issue belongs to the Section Molecular Neurobiology)

Metal-Organic Frameworks: Pioneering New Solutions for Biomedical Challenges

edited by

David Rodríguez-Lucena

and

Belén Begines

submission deadline 31 Jul 2025 | Viewed by 98 | Submission Open

Keywords: MOFs; biomedical advances; drug delivery; personalized medicine; biomedical imaging; bio-sensor; smart MOFs; nanomedicine; cancer therapy

(This special issue belongs to the Section Materials Science)

Microgravity, Cell Shape and Gene Expression: State of the Art, Challenges and Prospects

edited by Masahiro Terada

submission deadline 31 Jul 2025 | Viewed by 97 | Submission Open

Keywords: microgravity; space radiation; closed environment; space flight; parabolic flight; clinostat; human; rodent; microorganism; countermeasure; artificial gravity

(This special issue belongs to the Section Molecular Biology)

Insights in Metabolomics: Chromatography and Mass Spectrometry Applications in Cancer Research

edited by

Catarina Luís

submission deadline 31 Jul 2025 | Viewed by 96 | Submission Open

Keywords: metabolomics; chromatography; mass spectrometry; molecular oncology; cancer pathways; precision medicine

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Interaction Between Tumor Microenvironment and Cancer Stem Cell

edited by

Na Luo

submission deadline 31 Jul 2025 | Viewed by 95 | Submission Open

Keywords: tumor microenvironment; cancer stem cells; innate and adaptive immunity; mesenchymal stromal cells

(This special issue belongs to the Section Molecular Oncology)

Musculoskeletal Injuries and Conditions: From Pathophysiology to Novel Therapeutic Approaches

edited by

Jai-Hong Cheng

submission deadline 31 Jul 2025 | Viewed by 95 | Submission Open

Keywords: musculoskeletal disorder; pathophysiology; diagnosis; biomarkers; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Therapeutic Potential of Organic Compound in Diseases

edited by

Katarzyna Kotwica-Mojzych

submission deadline 31 Jul 2025 | Viewed by 93 | Submission Open

Keywords: organic compounds; chemical analysis; medicinal chemistry; organic chemistry; organic synthesis; characterization techniques; cancers; chronic diseases; civilization diseases; degenerative and neurodegenerative diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Extracellular Vesicles as Biomarkers in Personalized Medicine

edited by Thi Thuy Nguyen Dao

submission deadline 31 Jul 2025 | Viewed by 88 | Submission Open

Keywords: extracellular vesicles; biomarkers; cancer; cardiovascular diseases; neurodegenerative diseases; personalized medicineg

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancing Precision Medicine in Urological Cancers: Integrating Multi-Omics and Optimizing Therapeutic Approaches

edited by Magaly Martinez-Ferrer

submission deadline 31 Jul 2025 | Viewed by 88 | Submission Open

Keywords: prostate cancer; proteomics; metabolomics; precision medicine; biomarker

(This special issue belongs to the Section Molecular Oncology)

DNA Methylation and Histone Modifications in Cellular Homeostasis

edited by

Xiao Chen

submission deadline 31 Jul 2025 | Viewed by 88 | Submission Open

Keywords: chromatin modification; DNA methylation; histone post-translational modifications; transcriptional regulation; epigenetic landscapes; cellular homeostasis; epigenome analysis; eukaryotic evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Age-Dependence of Neuroimmune Reactions

edited by

Babak Baban

submission deadline 31 Jul 2025 | Viewed by 87 | Submission Open

Keywords: age; neuroimmune dynamics; neuroimmune interaction; immune system; the central nervous system; age-related neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Molecular Immunology)

Advances in the Molecular Diagnosis and Treatment of Neurodegenerative Diseases

edited by

Bruno Manadas

submission deadline 31 Jul 2025 | Viewed by 87 | Submission Open

Keywords: neurodegenerative disorders; biomarkers; treatment; omics; systems biology

(This special issue belongs to the Section Molecular Neurobiology)

NURR1 Biology in Neurological Disorders and Other Diseases

edited by

Ángel Juan García-Yagüe

submission deadline 31 Jul 2025 | Viewed by 87 | Submission Open

Keywords: NURR1; regulation; chronic diseases; inflammation; neurodegenerative diseases; neurological diseases; cancer; inflammatory diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Genetics, Genomics and Breeding in Field Crops

edited by

Xianzhong Feng

submission deadline 31 Jul 2025 | Viewed by 87 | Submission Open

Keywords: field crop; genomics; molecular genetics; breeding technologies; germplasm utilization

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advanced of Layered Double Hydroxides (LDH) for Corrosion Protection

edited by

Henryk Kania

submission deadline 31 Jul 2025 | Viewed by 85 | Submission Open

Keywords: layered double hydroxide (LDHs); corrosion resistance; coatings; corrosion products

(This special issue belongs to the Section Materials Science)

Advancing Forensic Genetics Through Massive Parallel Sequencing

edited by Daniel Kling

submission deadline 31 Jul 2025 | Viewed by 84 | Submission Open

Keywords: forensic genetics; molecular biology; genetics and aging; biochemistry; population genetics; fo-rensic statistics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Extracellular Vesicles: Unraveling Molecular Pathways for Targeted Therapy

edited by

Ssang-Goo Cho

submission deadline 31 Jul 2025 | Viewed by 83 | Submission Open

Keywords: stem cells; cellular reprogramming; extracellular vesicles; exosomes; targeted therapy; regenerative medicine; rejuvenation; anti-inflammation therapy; pain syndrome

(This special issue belongs to the Section Molecular Biology)

Advances in Molecular Research on Axon Demyelination and Remyelination

edited by Rachelle Frazen

submission deadline 31 Jul 2025 | Viewed by 76 | Submission Open

Keywords: myelin; Schwann; OPC/oligodendrocytes; axon— glia crosstalk; peripheral neuropathies; multiple sclerosis; remyelination; myelin maintenance; molecular targets; signaling pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Progress in Spectroscopic Studies of Biomolecules

edited by

Mahmoud Ghomi

submission deadline 31 Jul 2025 | Viewed by 76 | Submission Open

Keywords: spectroscopic; nuclear magnetic resonance; X-ray; neutron scattering; biomolecular structure

(This special issue belongs to the Section Molecular Biophysics)

Impact of Vitamins on Cardiovascular Disease

edited by León Ferder

submission deadline 31 Jul 2025 | Viewed by 73 | Submission Open

Keywords: vitamins; cardiovascular disease; atherosclerosis; hypertension; heart failure; endothelial dysfunction; mitochondrial metabolism; oxidative stress; longevity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Light-On Molecular Probes for Biomedical Analysis

edited by Aleksey A. Vasilev

submission deadline 31 Jul 2025 | Viewed by 72 | Submission Open

Keywords: fluorogenic dyes; nucleic acid binders; nucleic acid labels; molecular probes; fluorogenic polymers and nanomaterials

(This special issue belongs to the Section Materials Science)

Galectins (Gals), 2nd Edition

edited by

Luciano Pirone

submission deadline 10 Aug 2025 | 3 articles | Viewed by 1385 | Submission Open

Keywords: galectin; inhibitors; cancer; inflammation; glycans; drug design; modeling; biomarkers

(This special issue belongs to the Section Molecular Biology)

Anti-Cancer, Anti-Inflammatory, and Antioxidation Active Substances: 3rd Edition

edited by

Ming-Ju Hsieh

submission deadline 15 Aug 2025 | 2 articles | Viewed by 1167 | Submission Open

Keywords: anti-inflammatory; anti-cancer; antioxidants; antiproliferative; antiviral; antibacterial; antibodies; molecular mechanism; chemoresistance; molecular biology

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Characterization and Applications of Nanomaterials in Nanomedicine and Cancer Therapy

edited by

Costica Caizer

submission deadline 15 Aug 2025 | 1 articles | Viewed by 899 | Submission Open

Keywords: nanomaterials (preparation methods; characterization techniques; properties); theoretical studies of nanomaterials and computational simulations; biocompatibility and biofunctionalization; applications in nanomedicine; applications in cancer therapy; drug delivery; nanoparticle imaging; magnetic resonance imaging (MRI); contrast agents; nanotheranostics

(This special issue belongs to the Section Molecular Nanoscience)

Molecular and Cellular Therapies Barriers and Opportunities

edited by

O’neil W. Guthrie

submission deadline 15 Aug 2025 | Viewed by 117 | Submission Open

Keywords: gene therapy; gene editing; RNA therapy; RNA editing; protein therapy; stem cells; cell therapy; genomics; proteomics; molecular pathology

(This special issue belongs to the Section Molecular Biology)

The Role of the Gut and Oral Microbiota in Neurodevelopment: Molecular Biological Insights

edited by Ioannis Alexandros Charitos

submission deadline 15 Aug 2025 | Viewed by 93 | Submission Open

Keywords: neuroscience; central nervous system; peripheral nervous system; human microbiota; metabolome; gut– oral-microbiota– brain axis; neurodevelopment disorders; cognitive modulation; neurodegenerative diseases; psychobiotics

(This special issue belongs to the Section Molecular Microbiology)

Novel Therapeutic Strategies for Gynecological Cancer

edited by

Masayuki Sekine

submission deadline 15 Aug 2025 | Viewed by 72 | Submission Open

Keywords: gynecological cancer; therapeutic strategies; genomic medicine; multimodality treatment; biomarker; molecular targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Pathologies and Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

edited by

Elisa Oltra

submission deadline 20 Aug 2025 | 4 articles | Viewed by 32543 | Submission Open

Keywords: myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); diagnosis; post-exertional malaise (PEM); comorbidity; biomarker; therapy; immunity; microbiome

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Targeted Therapies of Breast Cancer

edited by

Piotr Dzięgiel

, Karolina Jabłońska and

Katarzyna Nowińska

submission deadline 20 Aug 2025 | 8 articles | Viewed by 27237 | Submission Open

Keywords: breast cancer; cancer progression; cancer metastasis; tumor microenvironment; molecular mechanisms; molecular markers; epigenetics; genomics; transcriptomics; EMT; targeted therapies; signaling pathways; exosomes; EMT; hormonal regulation; drugs; apoptosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Retinal Degenerative Diseases: 2nd Edition

edited by

Diego García-Ayuso

and

Johnny Di Pierdomenico

submission deadline 20 Aug 2025 | 5 articles | Viewed by 21112 | Submission Open

Keywords: retina; photoreceptor degenerative diseases; inherited retinal degenerations; glaucoma; retinal pigment epithelial cells; retinal ganglion cells (RGCs); neuronal degeneration; glial activation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Bioactive Nutrients Promoting Human Health

edited by

Baojun Xu

submission deadline 20 Aug 2025 | 10 articles | Viewed by 18891 | Submission Open

Keywords: bioactive nutrients; antioxidants; anti-inflammatory; disease prevention; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Plant Metabolomics: Uncovering the Hidden World of Plant Secondary Metabolites

edited by

Jen-Tsung Chen

submission deadline 20 Aug 2025 | 12 articles | Viewed by 18091 | Submission Open

Keywords: metabolomics; secondary metabolites; plant biochemistry; mass spectrometry; NMR spectroscopy; plant signaling pathways; natural products; chemical ecology; metabolic profiling; phytochemicals; medicinal plants; herbal medicines

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of Trace Elements in Nutrition and Health

edited by Jie Feng

submission deadline 20 Aug 2025 | 8 articles | Viewed by 17277 | Submission Open

Keywords: trace elements; nutrition; health; function; disease; metabolism; homeostasis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advanced Research of Skin Inflammation and Related Diseases

edited by

Filomena Napolitano

and

Valentina Giudice

submission deadline 20 Aug 2025 | 9 articles | Viewed by 15982 | Submission Open

Keywords: skin; inflammation; molecular target; inflammatory skin diseases; psoriasis; urticaria; atopic dermatitis; systemic sclerosis; skin fibrosis; immune system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 651-700 on page 14 of 68.

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