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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Environmental Microorganisms and Pathogen Infections

edited by

Jadwiga Wyszkowska

and

Magdalena Zaborowska

submission deadline 31 Dec 2026 | 1 articles | Viewed by 744 | Submission Open

Keywords: environmental microbiome; pathogens; resistance genes; molecular adaptation; microbial interactions; anthropogenic pollution; functional gene expression; ecosystem health

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Orthopedic Materials

edited by Seung Hun Lee

submission deadline 31 Dec 2026 | 1 articles | Viewed by 739 | Submission Open

Keywords: orthopedic biomaterials; bone regeneration; musculoskeletal system; muscle tissue engineering; 3D bioprinting; functional scaffolds; hydrogels; cell–material interaction; regenerative medicine; myogenic differentiation

(This special issue belongs to the Section Materials Science)

Molecular Advances in Obstetrical and Gynaecological Disorders: 2nd Edition

edited by

Panagiotis Christopoulos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 717 | Submission Open

Keywords: gynaecological disorders; obstetrical disorders; gynaecological diseases; genetic markers; molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metallopharmaceuticals: Current Trends and Future Perspectives in Cancer Immunoediting

edited by

Marialuisa Piccolo

and

Claudia Riccardi

submission deadline 31 Dec 2026 | Viewed by 710 | Submission Open

Keywords: metal-based drugs; anticancer activity; mechanisms of action; tumor microenvironment; immune cell regulation; cancer immunity; metal–protein interactions; metal–nucleic acid interactions

(This special issue belongs to the Section Molecular Pharmacology)

Research Progress of Orthopedic Materials

edited by Robert Karpiński

submission deadline 31 Dec 2026 | Viewed by 705 | Submission Open

Keywords: biocompatibility; biomaterials; orthopedic implants; hydroxyapatite; biodegradable polymers; tissue engineering; bioactive surfaces; bone cements; bone regeneration; antibacterial coatings

(This special issue belongs to the Section Materials Science)

Application of Polysaccharides and Their Derivatives in Drug Delivery

edited by

Pakorn Kraisit

submission deadline 31 Dec 2026 | 1 articles | Viewed by 703 | Submission Open

Keywords: polysaccharides; drug delivery; biomaterials; nanoparticles; controlled release; targeted delivery; hydrogels; biopolymers; drug carriers; biomedical applications

(This special issue belongs to the Section Macromolecules)

Integrative Perspectives on Plant Signaling Pathways: From Growth Regulation to Stress Resilience and Adaptive Responses

edited by

Raheel Munir

submission deadline 31 Dec 2026 | Viewed by 702 | Submission Open

Keywords: plant signaling; hormonal regulation; plant growth and development; plant-peptide signal transduction; abiotic/biotic stress resilience; omics; molecular mechanisms; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Ion Channels in Human Health and Diseases

edited by

Ye Chun Ruan

and Jinghui Guo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 693 | Submission Open

Keywords: ion channels; channelopathies; electrophysiology; organ systems; human diseases; membrane excitability; pharmacology and drug discovery; translational medicine

(This special issue belongs to the Section Molecular Biology)

Synthesis and Activity of Natural Products and Analogues

edited by

Jin-pyo An

submission deadline 31 Dec 2026 | 1 articles | Viewed by 683 | Submission Open

Keywords: natural products; functional food; synthesis; high-resolution mass spectrometry; bioactive compound

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Research Progress of Nanocarriers

edited by

Diana Rita Barata Costa

submission deadline 31 Dec 2026 | 1 articles | Viewed by 683 | Submission Open

Keywords: controlled release; drug delivery systems; multimodal nanoplatforms; nanoparticles; precision medicine; stimuli-responsive nanocarriers; theranostics; therapeutic delivery; translational na-nomedicine

(This special issue belongs to the Section Molecular Nanoscience)

Plant Breeding and Genetics: New Findings and Perspectives, 2nd Edition

edited by

Andrés J. Cortés

submission deadline 31 Dec 2026 | 2 articles | Viewed by 672 | Submission Open

Keywords: quantitative genetics; classical plant breeding; marker assisted selection; genomic selection; speed breeding; gene editing and biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in Photodynamic Therapy for Antibacterial and Anticancer Applications

edited by

Sandile Phinda Songca

submission deadline 31 Dec 2026 | Viewed by 660 | Submission Open

Keywords: photodynamic therapy (PDT); sonodynamic therapy (SDT); radiodynamic therapy (RDT); chemodynamic therapy (CDT); photosensitizers; sonosensitizers; radiosensitizers; antimicrobial PDT; antimicrobial SDT; antimicrobial RDT; anticancer therapy; drug resistance; bacterial biofilms; reactive oxygen species; nanocarriers; nanoscale metal–organic frameworks; immunogenic cell death; targeted drug delivery; combination therapeutics

(This special issue belongs to the Section Molecular Biology)

Azoles and Fused Heterocycles in Antimicrobial Drug Discovery: Synthesis, Mechanisms, and Applications

edited by

Esra Tatar

submission deadline 31 Dec 2026 | 1 articles | Viewed by 651 | Submission Open

Keywords: drug design and discovery; bioactive molecules; azoles and fused heterocycles; antimicrobials

(This special issue belongs to the Section Molecular Pharmacology)

Individualised Therapies for Rare Disorders

edited by Paul Gissen

submission deadline 31 Dec 2026 | 1 articles | Viewed by 619 | Submission Open

Keywords: individualised therapies; personalised medicine; rare diseases; omics; gene therapy; molecular pathways; mechanistic discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metal Toxicity and Particle Toxicity

edited by Alicja Piotrowska-Niczyporuk

submission deadline 31 Dec 2026 | 1 articles | Viewed by 594 | Submission Open

Keywords: metals; particles; toxicity; microplastic; environment pollution; animals; plants; algae

(This special issue belongs to the Section Molecular Toxicology)

Enzyme Inhibitory Assessment and Molecular Docking Studies of Natural and Synthetic Heterocyclic Compounds

edited by

Milen G. Bogdanov

submission deadline 31 Dec 2026 | Viewed by 589 | Submission Open

Keywords: heterocycles; enzyme inhibition; docking studies; drug discovery

(This special issue belongs to the Section Molecular Pharmacology)

Activity and Efficacy Evaluation of Natural Products

edited by Fazrena Nadia Md Akhir

submission deadline 31 Dec 2026 | 2 articles | Viewed by 581 | Submission Open

Keywords: natural products; bioactivity; pharmacological efficacy; medicinal plants; marine bioresources; anticancer; anti-inflammatory; synergistic effects; AI-guided discovery; metabolomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Next-Generation Natural Products in Drug Discovery: From Ethnopharmacology to Precision Medicine

edited by Idris Adewale Ahmed

submission deadline 31 Dec 2026 | Viewed by 572 | Submission Open

Keywords: phytochemicals; pharmacodynamics; pharmacokinetics; formulation strategies; commercialization; nanotechnology; delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Effects of Nutrients and Functional Foods on Immune and Inflammatory Responses

edited by

Yaxi Zhou

and Wenjie Yan

submission deadline 31 Dec 2026 | 1 articles | Viewed by 554 | Submission Open

Keywords: nutrients and bioactive compounds; functional foods; immune response; chronic inflammation; inflammatory pathways; cytokines and chemokines; gut–immune axis; oxidative stress; immunomodulation; in vitro and in vivo models

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Decoding Animal Reproduction: From Molecular Mechanisms to Breeding Innovations

edited by

Mingtian Deng

submission deadline 31 Dec 2026 | 1 articles | Viewed by 542 | Submission Open

Keywords: embryo; epigenetics; multi-omics; breeding

(This special issue belongs to the Section Molecular Biology)

Amino Acid Nutrition and Human Health

edited by

Terrence Piva

submission deadline 31 Dec 2026 | Viewed by 539 | Submission Open

Keywords: amino acids; dietary intake; metabolic disease; starvation; obesity; supplementation; parental nutrition; gene expression; tumour metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular and Physiological Effects of Exercise in Cachexia

edited by

Marilia Seelaender

and

Fábio Santos Lira

submission deadline 31 Dec 2026 | Viewed by 536 | Submission Open

Keywords: cachexia; skeletal muscle mass; skeletal muscle strength; exercise; muscle metabolism

(This special issue belongs to the Section Molecular Biology)

Nanomaterials in Tissue Engineering and Regenerative Medicine: Recent Advances and Future Prospects

edited by

Kapil D. Patel

submission deadline 31 Dec 2026 | Viewed by 534 | Submission Open

Keywords: nanoparticles; nanofibers; nanotubes; nanocomposites; hydrogels; ceramics; bioactive glass nanoparticles; tissue engineering; regenerative medicine

(This special issue belongs to the Section Molecular Nanoscience)

Sustainable Polymers: From Molecular Fundamentals to Real-World Applications

edited by

Zahid Iqbal Khan

submission deadline 31 Dec 2026 | Viewed by 527 | Submission Open

Keywords: sustainable polymers; recycled plastics; bio-based polymers; polymer blends; nanocomposites; membrane technology; water purification; CO2 capture

(This special issue belongs to the Section Materials Science)

Molecular Engineering of Biomaterials for Advanced Additive Manufacturing

edited by

Johari Yap Abdullah

submission deadline 31 Dec 2026 | 1 articles | Viewed by 511 | Submission Open

Keywords: molecular engineering; biomaterials; polymer chemistry; additive manufacturing; 3D printing; supramolecular interactions; surface chemistry; biocompatibility; degradation mechanisms; functional polymers; bioactive materials; computational modeling; tissue engineering; regenerative medicine

(This special issue belongs to the Section Materials Science)

Cellular Mechanisms of Pulmonary Arterial Hypertension

edited by

David P Marciano

and Saurabh Aggarwal

submission deadline 31 Dec 2026 | Viewed by 510 | Submission Open

Keywords: pulmonary arterial hypertension (PAH); pulmonary vascular remodeling; endothelial cells; endothelial dysfunction; smooth muscle cells; hyperplasia; pericytes; fibroblasts; monocytes; macrophage; neutrophil; mechanotransduction; oxidative stress; cytokines; extracellular vesicles; extracellular matrix; epigenetics; metabolism; biomarkers; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genomic and Molecular Insights into Emerging and Reemerging Pathogens

edited by

Fabio Scarpa

submission deadline 31 Dec 2026 | Viewed by 507 | Submission Open

Keywords: pathogens genomic analysis; evolution transmission dynamics; pathogenic mechanisms; viruses; bacteria; fungi; parasites; next-generation sequencing; metagenomics; bioinformatics; genetic variations; adaptive mutations; host–pathogen interactions; emerging pathogens; molecular epidemiology; host immune responses; pathogen genetics

(This special issue belongs to the Section Molecular Immunology)

Interfacial Chemistry, Conformational Dynamics, and Molecular Assemblies of Amphiphilic Molecules

edited by

Mihalj Poša

submission deadline 31 Dec 2026 | 1 articles | Viewed by 506 | Submission Open

Keywords: amphiphiles; surfactants; surface equations of state (SEOS); binary mixture of amphiphiles; conformations of amphiphiles; micellar aggregates; solubilization; thermodynamics of micelle formation; Jesús Gracia-Fadrique's surface pressure; enthalpy–entropy compensation

(This special issue belongs to the Section Biochemistry)

Mechanisms and Applications of Heterosis in Plants

edited by

Wenxin Liu

submission deadline 31 Dec 2026 | Viewed by 499 | Submission Open

Keywords: heterosis; mechanism; prediction; application; breeding; plant

(This special issue belongs to the Section Molecular Plant Sciences)

Research Progress on Cancer Biomarkers and Molecular Targets

edited by

José Vargas

submission deadline 31 Dec 2026 | 1 articles | Viewed by 492 | Submission Open

Keywords: cancer biomarkers; molecular targets; cellular senescence; autophagy; epigenetics; prognosis; tumor microenvironment; therapy resistance; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms of Neuroendocrine Regulations in Health and Pathology

edited by

Michael Ugrumov

and

Serguei Fetissov

submission deadline 31 Dec 2026 | 1 articles | Viewed by 490 | Submission Open

Keywords: neuroendocrine system; brain; hypothalamus; adenohypophysis; endocrine glands; (neuro)hormones; ontogenesis; neuroendocrine disorders

(This special issue belongs to the Section Molecular Neurobiology)

Emerging Biomarkers of Inflammation and Cancer: From Molecular Pathways to Clinical Stratification

edited by

Ciriaco Carru

and

Donatella Coradduzza

submission deadline 31 Dec 2026 | Viewed by 483 | Submission Open

Keywords: chronic inflammation; cancer biomarkers; inflammatory indices; non-coding RNAs; clinical translation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Machine Learning–Based Perspectives in Plant Biology

edited by Silas Pessini Rodrigues

submission deadline 31 Dec 2026 | Viewed by 479 | Submission Open

Keywords: machine learning; artificial intelligence; plant molecular biology; multi-omics integration; feature selection; gene prioritization; plant stress responses; high-throughput phenotyping; crop improvement; biotechnology

(This special issue belongs to the Section Molecular Informatics)

Ovarian Insufficiency: From Molecular Pathology to Novel Therapeutic Approach

edited by Aleksandar Ljubić

submission deadline 31 Dec 2026 | Viewed by 458 | Submission Open

Keywords: ovarian insufficiency; premature ovarian insufficiency; molecular pathology; regenerative medicine; stem cell therapy; platelet-rich plasma; epigenetics; intraovarian treatment; ovarian stem cells; mitochondrial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

3D Printing and Biomaterials for Hearing and Balance Restoration

edited by

Chenkai Dai

submission deadline 31 Dec 2026 | Viewed by 453 | Submission Open

Keywords: hearing; balancing; 3D printing; biomaterial

(This special issue belongs to the Section Materials Science)

Novel Therapeutic Strategies for Hepatocellular Carcinoma

edited by

Soon Kyu Lee

submission deadline 31 Dec 2026 | Viewed by 439 | Submission Open

Keywords: hepatocellular carcinoma; immune checkpoint inhibitors; tyrosine kinase inhibitors; radiotherapy; embolization; surgery; transplantation

(This special issue belongs to the Section Molecular Oncology)

Advances in Plant–Pathogen Interactions (4th Edition)

edited by

Fucheng Lin

submission deadline 31 Dec 2026 | Viewed by 434 | Submission Open

Keywords: host; effection; pathogenicity; pathogen; plant immunity; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Study of Foodborne Pathogens

edited by

Valeria Russini

and

Maria Laura De Marchis

submission deadline 31 Dec 2026 | Viewed by 434 | Submission Open

Keywords: foodborne pathogens; microbiology; molecular analysis; foodborne outbreak investigation; epidemiology; listeria monocytogenes; salmonella; campylobacter; virulence genes; antimicrobial gene; WGS; NGS

(This special issue belongs to the Section Molecular Microbiology)

Cutting-Edge Research and Advancements in Neurodegenerative Diseases

edited by Meera Soundararajan

submission deadline 31 Dec 2026 | Viewed by 430 | Submission Open

Keywords: neurodegenerative disorders; neurons; Alzheimer’s disease; Parkinsons disease; Amyotrophic Lateral Sclerosis (ALS); prion diseases; Huntington disease

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Three-Dimensional Cell Culture: From Bioengineering Innovation and Therapeutic Application

edited by Jong-Young Kwak

submission deadline 31 Dec 2026 | 1 articles | Viewed by 422 | Submission Open

Keywords: 3D culture; biomaterials; scaffold; tissue engineering; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Molecular Dynamics of the Oral Microbiome in Periodontal Health and Disease

edited by

John Yun Niu

submission deadline 31 Dec 2026 | Viewed by 422 | Submission Open

Keywords: oral microbiome; periodontics; tissue regeneration; bioinformatics; biomarkers; host–microbiome interactions; molecular dynamics

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Optoelectronic Materials

edited by Muhammad Umair Shahid

submission deadline 31 Dec 2026 | Viewed by 412 | Submission Open

Keywords: organic solar cells; DSSCs; perovskite solar cells; donor–acceptor systems; optoelectronic devices; charge separation; sensors; quantum dots; 2D materials; machine learning in materials science

(This special issue belongs to the Section Materials Science)

Serum Amyloid A: Established Roles and Emerging Questions in Health and Disease

edited by Preetha Shridas

submission deadline 31 Dec 2026 | Viewed by 410 | Submission Open

Keywords: Serum Amyloid A; high-density lipoprotein; acute inflammation; chronic inflammatory

(This special issue belongs to the Section Biochemistry)

Mechanisms Linking Gut Microbiota to Metabolic Diseases

edited by Jing Ji,

Hongyuhang Ni

and Aman Khan

submission deadline 31 Dec 2026 | Viewed by 386 | Submission Open

Keywords: gut microbiota; metabolic diseases; probiotics; prebiotics; obesity; microbial metabolites; host–microbe interaction; metabolic inflammation; intestinal barrier; hyperuricemia; diabetes; non-alcoholic fatty liver disease

(This special issue belongs to the Section Molecular Microbiology)

Research into Biomarkers for Psychiatric Disorders

edited by

João Victor Silva Nani

submission deadline 31 Dec 2026 | Viewed by 386 | Submission Open

Keywords: psychiatric disorders; molecular biomarkers; single-cell transcriptomics; neuroimmune interface; peripheral blood mononuclear cells (PBMCs); precision psychiatry; multi-omics integration; extracellular vesicles; liquid biopsy; neurogenomics

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Protein Dynamics, Binding and Allostery

edited by Huawei Zhang

submission deadline 31 Dec 2026 | Viewed by 371 | Submission Open

Keywords: protein dynamics; protein interaction; allostery; conformational regulation; drug design

(This special issue belongs to the Section Molecular Biology)

Research Advances in Food Packaging Materials

edited by Marília Miotto and

Larissa Nardini Carli

submission deadline 31 Dec 2026 | Viewed by 366 | Submission Open

Keywords: active food packaging; intelligent packaging; smart packaging; biodegradable polymers; bio-based materials; food safety; antimicrobial packaging; antioxidant packaging; sustainable packaging; shelf-life extension

(This special issue belongs to the Section Materials Science)

Molecular Advances on Sickle Cell Disease

edited by

Panicos Shangaris

submission deadline 31 Dec 2026 | Viewed by 364 | Submission Open

Keywords: sickle cell disease; hemoglobinopathy; vaso-occlusion; fetal hemoglobin induction; genome editing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Perspectives in Molecular Plant Pathology

edited by

Göksel Özer

and

Rachid Lahlali

submission deadline 31 Dec 2026 | Viewed by 363 | Submission Open

Keywords: molecular plant pathology; real-time PCR; gene expression; molecular markers; marker-assisted selection; genetic diversity; pathogen diagnostics; transcriptomics; genome editing; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Targeted Anticancer Therapeutics: Mechanisms, Resistance, Tumor Microenvironment, and Translational Advances

edited by Shakti Prasad Pattanayak

submission deadline 31 Dec 2026 | 1 articles | Viewed by 358 | Submission Open

Keywords: cancer metabolism; drug resistance; tumor microenvironment; immunometabolism; targeted therapy; anticancer therapeutics; autophagy; oxidative stress; cancer immunotherapy; translational oncology

(This special issue belongs to the Section Molecular Oncology)

Displaying special issue 2151-2200 on page 44 of 64.

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