Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Molecular Mechanisms and Therapeutic Targets in Brain Tumor Pathogenesis

edited by Mugurel Petrinel Radoi

submission deadline 31 Dec 2025 | Viewed by 103 | Submission Open

Keywords: brain tumors; molecular pathogenesis; glioma biomarkers; tumor microenvironment; neuro-oncology; targeted therapy; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Pharmacology for Neuropathic and Chronic Pain Management

edited by

Kuthati Yaswanth

and

Chih-Shung Wong

submission deadline 31 Dec 2025 | Viewed by 103 | Submission Open

Keywords: neuropathic pain; diabetic neuropathy; chronic pain; DPP-4 inhibitors; SGLT2 inhibitors; pain pharmacology; neuroinflammation; glial activation; ion channels; cannabinoids; endogenous peptides; epigenetic modulation; extended-release formulations; drug repurposing; analgesic mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Oxidative–Inflammatory Crosstalk in Retinal Pigment Epithelium: Models, Mechanisms, and Modulators

edited by

Min-Yen Hsu

submission deadline 31 Dec 2025 | Viewed by 102 | Submission Open

Keywords: retinal pigment epithelium (RPE); oxidative stress; inflammation; immunometabolism; mitochondrial dysfunction; inflammasome; IL-8/VEGF signaling; heavy-metal toxicity; extracellular vesicles; antioxidant therapy

(This special issue belongs to the Section Molecular Immunology)

Pharmacological Agents for Soft Tissue and Articular Injections: From Mechanisms to Clinical Applications

edited by

Carmelo Pirri

submission deadline 31 Dec 2025 | Viewed by 101 | Submission Open

Keywords: injectable pharmacological agents; musculoskeletal disorders; injection therapies; platelet-rich plasma (PRP); hyaluronic acid

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Metabolism of Alzheimer’s Disease

edited by

Rebecca Piccarducci

and Maria Letizia Trincavelli

submission deadline 31 Dec 2025 | Viewed by 100 | Submission Open

Keywords: Alzheimer’ s disease; brain metabolism; insulin resistance; lipid metabolism; APOE ε 4; metabolic targets; insulin-sensitizing drugs; lifestyle and metabolic interventions

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms Underlying the Pathogenesis and Treatment of Gastrointestinal Disorders

edited by

Andrzej Pławski

submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open

Keywords: gastrointestinal disorders; molecular mechanisms; diagnosis; treatment; precision medicine; biomarkers; gastrointestinal cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

RNA-Mediated Post-Transcriptional Regulation in Bacteria Roles of Small RNAs, Small Proteins, and RNA Modifications

edited by Karl M Thompson

submission deadline 31 Dec 2025 | Viewed by 99 | Submission Open

Keywords: bacterial post-transcriptional regulation; small RNAs (sRNAs); small open reading frames (smORFs); RNA modifications; epitranscriptomics

(This special issue belongs to the Section Molecular Biology)

Molecular Perspective of Alzheimer’s Disease

edited by

Philippe Poindron

submission deadline 31 Dec 2025 | Viewed by 98 | Submission Open

Keywords: Alzheimer’ s disease; amyloid peptide (toxic conformation); mutations (gamma-secretase); GWAS; risk factors; new treatment (monoclonal antibodies)

(This special issue belongs to the Section Molecular Neurobiology)

Endocrine–Immune Crosstalk in Human Reproductive Health and Pathology

edited by Juan Pablo Mackern-Oberti

submission deadline 31 Dec 2025 | Viewed by 96 | Submission Open

Keywords: T cells; B cells; autoimmune disease; reproduction; immunemodulation; inflammation; endocrinology; lactation

(This special issue belongs to the Section Molecular Immunology)

Emerging Environmental Exposures and Molecular Disruption Mechanisms in Human Health

edited by

David Lozano-Paniagua

submission deadline 31 Dec 2025 | Viewed by 95 | Submission Open

Keywords: environmental exposure; epigenetic; exposome; molecular biomarkers; molecular toxicology

(This special issue belongs to the Section Molecular Toxicology)

Next Generation Sequencing in Human Diseases

edited by

Manuel Muro

submission deadline 31 Dec 2025 | Viewed by 90 | Submission Open

Keywords: NGS; single-cell analysis; metagenomics; forensic DNA analysis; precision medicine; genetic diagnostics; transplant monitoring; cell-free DNA; new allele and variant discovery

(This special issue belongs to the Section Molecular Informatics)

Molecular Engineering in Insoluble Antibacterial Particle for Medical Devices

edited by Ole T. Jensen

submission deadline 31 Dec 2025 | Viewed by 89 | Submission Open

Keywords: antibacterial; quaternary ammonium silica particles; bactericidal mechanism; antibacterial particle; medical devices

(This special issue belongs to the Section Materials Science)

Gene Regulation and Neurotoxicity in Alcohol Related Pathologies

edited by

Stefano Casalotti

submission deadline 31 Dec 2025 | Viewed by 89 | Submission Open

Keywords: alcohol; ethanol; gene expression; neurotoxicity; epigenetics; polymorphisms; neu-rons; glial cell; plasticity

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Adaptive Mechanisms in Plant Genetics

edited by

Gennaro Lettieri

submission deadline 31 Dec 2025 | Viewed by 88 | Submission Open

Keywords: forest genetics; breeding techniques; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Multiple Myeloma: Cancer Therapy and the Tumour Microenvironment

edited by Ruba Al Abdulla

submission deadline 31 Dec 2025 | Viewed by 87 | Submission Open

Keywords: multiple myeloma; cancer resistance; therapeutic strategies; stroma cells; cancer microenvironment; cancer immunity

(This special issue belongs to the Section Molecular Oncology)

Anticancer Drugs: Current Status and Future Directions

edited by

Mariano Martínez-Vázquez

submission deadline 31 Dec 2025 | Viewed by 87 | Submission Open

Keywords: anticancer drugs; hybrids; combinations; nanoparticles

(This special issue belongs to the Section Molecular Pharmacology)

Structural and Functional Analysis of Amino Acids and Proteins: 2nd Edition

edited by

Wenying Yan

submission deadline 31 Dec 2025 | Viewed by 86 | Submission Open

Keywords: protein structure; protein function; amino acids network; deep learning; bioinformatics; protein– protein interaction; drug discovery; biomarker

(This special issue belongs to the Section Molecular Informatics)

Molecular Mechanisms and Pathways Involved in Toxicant-Induced Stress

edited by

Maria Giulia Lionetto

and

Maria Elena Giordano

submission deadline 31 Dec 2025 | Viewed by 84 | Submission Open

Keywords: oxidative stress; cell death; biomarkers; toxicant exposure; environmental toxicology; cell signaling pathways

(This special issue belongs to the Section Molecular Toxicology)

Epigenetic and Transcriptional Regulation in Aquaculture: Immunity, Stress and Disease Prevention

edited by

Chan-Hee Kim

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: epigenetics; transcriptional regulation; trained immunity; DNA methylation; histone modifications; non-coding RNAs; disease prevention; aquaculture

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Nanomaterials for Cancer Treatment and Translational Medicine

edited by

Mingzhen Zhang

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: nanozymes; extracellular vesicles; drug delivery systems; cancer treatment; oxidative stress-related diseases; translational medicine

(This special issue belongs to the Section Molecular Nanoscience)

Gene Variants and Phenotypic Diversity: Insights into CFTR, SLC Transporters and Disease

edited by Veronique Ladeveze

submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open

Keywords: mutations; polymorphisms; alternative splicing; exon skipping; intron retention; CFTR (ABCC7); cystic fibrosis; SLC16a3; Alzheimer’ s disease; pulmonary and brain cancer

(This special issue belongs to the Section Molecular Genetics and Genomics)

Genome Editing and Biotechnology in Fruit Improvement

edited by Hongxia Miao

submission deadline 31 Dec 2025 | Viewed by 78 | Submission Open

Keywords: fruit improvement; horticultural crops; genome editing; biotechnology; molecular biology; plant genetics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances in Diagnosis and Treatment of Gynaecological Cancers

edited by

Chenhsuan Wu

submission deadline 31 Dec 2025 | Viewed by 76 | Submission Open

Keywords: gynecological oncology; molecular biomarkers; precision medicine; tumor microenvironment; targeted therapy; early detection; immunotherapy; genomic profiling; drug resistance; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Genetic Variants Involved in Breast and Ovarian Cancers

edited by

Chakravarthy Garlapati

submission deadline 31 Dec 2025 | Viewed by 69 | Submission Open

Keywords: breast and ovarian cancers; genetics; genomics; biomarkers; mutations; genetic variants; translational markers

(This special issue belongs to the Section Molecular Oncology)

Cancer Stem Cells as Key Immunotherapy Targets

edited by Cosmin Andrei Cismaru

submission deadline 31 Dec 2025 | Viewed by 46 | Submission Open

Keywords: cancer stem cells; immunotherapy; immune escape; tumor antigens; cancer recurrence

(This special issue belongs to the Section Molecular Immunology)

Advanced Molecular Research on Chronic Heart Failure

edited by

Marco Tana

submission deadline 1 Jan 2026 | 3 articles | Viewed by 6124 | Submission Open

Keywords: chronic heart failure (CHF); cardiovascular medicine; cardiac amyloidosis; biomarkers; translational ap-proaches; molecular approaches; pharmacological treatment; molecular mechanisms; molecular pathways; prognosis; clinical practice in CHF management

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Signatures in Overt Neurodegenerative Disease: Toward Precision Diagnosis and Classification

edited by

Jose Miguel Laffita-Mesa

submission deadline 1 Jan 2026 | 1 articles | Viewed by 1225 | Submission Open

Keywords: neurodegenerative diseases; molecular biomarkers; disease stratification; Parkinson’ s disease; Alzheimer’ s disease; spinocerebellar ataxia; precision medicine; digital PCR; circRNA; prognostic biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Poly- and Oligo-Saccharides as Pharmaceutical Agents in Biology and Medicine

edited by

Kevin H. Mayo

submission deadline 1 Jan 2026 | Viewed by 193 | Submission Open

Keywords: polysaccharides; oligosaccharides; isolation and purification; structural and functional analyses; biological mechanisms of action; cellular & molecular targets and interactions; pharmaceutical drug development; cancer; cardiovascular disease; diabetes

(This special issue belongs to the Section Molecular Biology)

Checkpoint Antibodies at the Crossroads: From Mechanisms to Multi-Modal Cancer Therapy

edited by Li Ye and Xuyao Zhang

submission deadline 10 Jan 2026 | 1 articles | Viewed by 1812 | Submission Open

Keywords: immune checkpoint inhibitors; tumor microenvironment; computational immunology; resistance mechanisms; multifunctional antibodies; rational combination design

(This special issue belongs to the Section Molecular Immunology)

From Microbes to Humans: Unveiling the Dynamic World of Carbonic Anhydrases (CAs)

edited by

Clemente Capasso

submission deadline 10 Jan 2026 | Viewed by 693 | Submission Open

Keywords: metalloenzymes; bacteria; pathogens; sulfonamides; inhibitors; activators; anti-infective agents; medicine; anticancer; neurodegenerative diseases; biomedical applications; biotechnology

(This special issue belongs to the Section Biochemistry)

Advances in Allergen Immunotherapy: Current Concepts and Future Directions

edited by

Constantinos Pitsios

submission deadline 10 Jan 2026 | Viewed by 118 | Submission Open

Keywords: allergen immunotherapy; oral immunotherapy; Hymenoptera venom; allergy extracts; adjuvants

(This special issue belongs to the Section Molecular Immunology)

Plant Epigenetic Memory Under Abiotic Stress

edited by

Md Mezanur Rahman

submission deadline 11 Jan 2026 | Viewed by 135 | Submission Open

Keywords: plant epigenetics; epigenetic memory; abiotic stress; DNA methylation; histone modification; chromatin remodeling; transgenerational inheritance; stress-responsive genes

(This special issue belongs to the Section Molecular Plant Sciences)

From Electronic Structure to Application: Computational Insights into Bioactive and Functional Molecules

edited by

Karolina Kula

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1880 | Submission Open

Keywords: molecular design; molecular modeling; substituent effect; reactivity descriptors; biological potential; in silico study; physicochemical properties; ADME; PASS; QSAR

(This special issue belongs to the Section Molecular Informatics)

Natural-Derived Bioactive Compounds in Disease Treatment

edited by

Adelina Vlad

and

Marilena Gilca

submission deadline 20 Jan 2026 | 7 articles | Viewed by 26008 | Submission Open

Keywords: medicinal plants; phytochemicals; vitamins; nutraceuticals; anti-oxidants; gene expression; protein expression; cellular signaling; nanoformulations

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms Underlying Vulnerability to Stress-Related Disorders

edited by Marta Pardo

submission deadline 20 Jan 2026 | 4 articles | Viewed by 24493 | Submission Open

Keywords: stress-related disorders; post-traumatic stress disorder; molecular mechanisms; pharmacological targets

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insight into Plant Bioactive Compounds

edited by

Karolina Wojtunik-Kulesza

submission deadline 20 Jan 2026 | 6 articles | Viewed by 19425 | Submission Open

Keywords: bioactivity; disease prevention; herbal medicines; antioxidants; qualitative analysis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Drug Delivery to the Central Nervous System: From Design, Synthesis, and Evaluation

edited by

Masaru Tanaka

submission deadline 20 Jan 2026 | 4 articles | Viewed by 18973 | Submission Open

Keywords: central nervous system; central nervous system diseases; drug delivery systems; blood– brain barrier; blood– cerebrospinal fluid barrier; drug design; nanomedicine; neuropharmacology; neuroprotective agents; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Endothelial Dysfunction: Fourth Edition

edited by

Catherine Davis

submission deadline 20 Jan 2026 | 6 articles | Viewed by 18448 | Submission Open

Keywords: vascular permeability; atherosclerosis; blood– brain barrier; endothelial adhesion molecules; vasodilation; thrombosis

(This special issue belongs to the Section Molecular Immunology)

Trends in Allergy and Autoimmunity: Pathogenesis, Biomarkers, and Treatment

edited by

Ilaria Mormile

submission deadline 20 Jan 2026 | 8 articles | Viewed by 17591 | Submission Open

Keywords: allergy; autoimmunity; autoimmune diseases; asthma; allergic rhinitis; urticaria; inflammation; molecular pathway; biomarkers; target therapy

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms for Skin Protection and Aging

edited by Wonchul Lim and

Tae-Gyu Lim

submission deadline 20 Jan 2026 | 4 articles | Viewed by 17148 | Submission Open

Keywords: skin photo-aging; skin inflammation; molecular biology; inner beauty; natural product; skin microbiome; skin wrinkle formation; skin dehydration; skin pigmentation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

A Molecular Perspective on the Genetics of Kidney Diseases

edited by Joaquim Calado

submission deadline 20 Jan 2026 | 6 articles | Viewed by 16105 | Submission Open

Keywords: kidney; genetics; solute transport; genomics; inflammation; dysmetabolism

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Mechanisms and Therapeutics in Neurological Diseases—4th Edition

edited by

Barbara Mroczko

submission deadline 20 Jan 2026 | 7 articles | Viewed by 15629 | Submission Open

Keywords: neurodegeneration; neuroinflammation; neurodegenerative diseases; neurodevelopmental disorders; tumor markers; specific proteins

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Research on Neurotransmitters

edited by

Mario Manto

Hiroshi Mitoma

and Jing-Ning Zhu

submission deadline 20 Jan 2026 | 6 articles | Viewed by 15432 | Submission Open

Keywords: neurotransmitter; GABA; glutamate; monoamines; dopamine; serotonin; norepinephrine; neuropeptides; nitric oxide; neurosteroids; stress; neurotrophins; epigenetics; gut– brain axis

(This special issue belongs to the Section Molecular Neurobiology)

Flow Cytometry: Applications and Challenges

edited by

Alessandra Falda

submission deadline 20 Jan 2026 | 7 articles | Viewed by 14797 | Submission Open

Keywords: flow cytometry; non-conventional flow cytometry; hematology; morphology; molecular tests; cell biology; immunology; target therapy; microbiology; antigens; functional mechanisms; new technologies

(This special issue belongs to the Section Molecular Biology)

Recent Advances of Novel Pharmaceutical Designs for Anti-Cancer Therapies, 3rd Edition

edited by

Bernhard Biersack

submission deadline 20 Jan 2026 | 7 articles | Viewed by 14661 | Submission Open

Keywords: cancer; anticancer drugs; drug design; targeted therapy; immunotherapy; molecular target; molecular mechanism; drug resistance

(This special issue belongs to the Section Molecular Pharmacology)

Genomic Research of Rare Diseases

edited by Shira Rockowitz and Piotr Sliz

submission deadline 20 Jan 2026 | 7 articles | Viewed by 14555 | Submission Open

Keywords: rare disease ontology; variants of uncertain significance; candidate genes; whole genome sequencing; long read whole genome sequencing; machine learning; multi-omics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Pathophysiology and Immunology Related to SARS-CoV-2 Infection

edited by

Vito D’Agnano

submission deadline 20 Jan 2026 | 9 articles | Viewed by 14034 | Submission Open

Keywords: SARS-CoV-2; COVID-19; immunology; pathophysiology; immunopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Involved in Sperm Development, Maturation, and Fertilization (3rd Edition)

edited by

Jan Tesarik

submission deadline 20 Jan 2026 | 4 articles | Viewed by 13821 | Submission Open

Keywords: sperm physiology; seminal plasma; extracellular vesicles; reproduction; spermatogenesis; capacitation; fertility

(This special issue belongs to the Section Molecular Biology)

Transporters in Health and Disease

edited by

Giuliano Ciarimboli

submission deadline 20 Jan 2026 | 7 articles | Viewed by 13632 | Submission Open

Keywords: transporters; disease; regulation; drugs; toxicity; signaling

(This special issue belongs to the Section Molecular Biology)

Bioactive Compounds in the Prevention of Chronic Diseases

edited by

Diego A. Moreno

Antonio J. Ruiz-Alcaraz

and

Paola Maycotte

submission deadline 20 Jan 2026 | 6 articles | Viewed by 13618 | Submission Open

Keywords: bioactives; chronic disease; inflammation; oxidative stress; obesity; diabetes; cancer

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 1051-1100 on page 22 of 69.

Go to page 20 21 22 23 24

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI