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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Male Infertility: Emerging Trends and Future Directions

edited by

Monica Muratori

and

Oumaima Ammar

submission deadline 29 Apr 2027 | Viewed by 55 | Submission Open

Keywords: male infertility; epigenetics; multi-omics; spermatogenesis; assisted reproduction; phytotherapy; artificial intelligence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Inflammasomes

edited by

Roberto Negro

submission deadline 30 Apr 2027 | 3 articles | Viewed by 4284 | Submission Open

Keywords: inflammasome; pyroptosis; innate immunity; cancer; neurodegenerative diseases; microbiota; gasdermin; ninjurin; drug screening; personalized treatments; multi-omics analysis

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms of Toxicity Caused by Environmental Pollutants

edited by Ivan Girón-Perez

submission deadline 30 Apr 2027 | 4 articles | Viewed by 2773 | Submission Open

Keywords: environmental pollutant; molecular toxicity; immunotoxicology; neurotoxicity

(This special issue belongs to the Section Molecular Toxicology)

From Mechanisms to Medicine: Cellular Insights into Pulmonary Hypertension

edited by

Swati Dabral

submission deadline 30 Apr 2027 | 2 articles | Viewed by 2686 | Submission Open

Keywords: vascular remodeling; cellular mechanisms; hypoxia; growth factors; inflammation

(This special issue belongs to the Section Molecular Biology)

Protein–Protein Interactions in Human Cancer

edited by

Geng Wu

submission deadline 30 Apr 2027 | 2 articles | Viewed by 2407 | Submission Open

Keywords: protein–protein interactions; protein–protein complexes; human cancer; signal transduction pathways; protein structure and function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Insights in Multiple Sclerosis (MS) and Neuroimmunology: 3rd Edition

edited by

Michael C. Levin

submission deadline 30 Apr 2027 | 2 articles | Viewed by 2081 | Submission Open

Keywords: neurodegeneration; neuroimmunology; macrophage; T-cell; B-cell; antibody; neurons; oligodendrocytes; axon; axonal damage; cell death; multiple sclerosis

(This special issue belongs to the Section Molecular Immunology)

Advances in Alzheimer's Disease and Related Dementias: From Pathogenesis to Therapeutics

edited by

Amal Kaddoumi

submission deadline 30 Apr 2027 | 1 articles | Viewed by 1153 | Submission Open

Keywords: Alzheimer's disease; cerebral amyloid angiopathy; blood–brain barrier; cerebrovascular dysfunction; neuroinflammation; therapeutic development; translational research

(This special issue belongs to the Section Molecular Neurobiology)

Lipid Metabolic and Signaling Dysregulations: From Molecular Mechanisms to Disease Pathogenesis

edited by Gergana M. Deevska

submission deadline 30 Apr 2027 | 2 articles | Viewed by 1131 | Submission Open

Keywords: lipid signaling; lipid metabolism; lipid homeostasis; metabolic dysregulation; signal transduction; disease pathogenesis

(This special issue belongs to the Section Molecular Biology)

New Research on Toxicology Research Models

edited by

Cláudia Maria Rosa Ribeiro

and

María Carolina Rocha-Pereira

submission deadline 30 Apr 2027 | 1 articles | Viewed by 1013 | Submission Open

Keywords: contaminants of emerging concern; aquatic organisms; in vitro; in vivo; mammalian approaches; mechanisms of toxicity; environmental risk assessment; one health

(This special issue belongs to the Section Molecular Toxicology)

New Insights into Gastroesophageal Tumors

edited by

Michela Guardascione

and Luisa Foltran

submission deadline 30 Apr 2027 | 2 articles | Viewed by 944 | Submission Open

Keywords: gastric cancer; esophageal cancer; biomarkers; target therapy; immunotherapy; NGS

(This special issue belongs to the Section Molecular Oncology)

Probiotics, Prebiotics, Synbiotics, and Gut Microbial Modulation in Intestinal Health and Disease

edited by Koji Yamamoto

submission deadline 30 Apr 2027 | 2 articles | Viewed by 871 | Submission Open

Keywords: gut microbiota; probiotics; prebiotics; synbiotics; inter-organ network; intestinal barrier; microbial metabolites; immunoregulation; multi-omics; inflammatory bowel disease; microbiome-based therapy

(This special issue belongs to the Section Molecular Microbiology)

Phytohormones in Plant Responses to Abiotic Stress

edited by

Marzena Kurowska

submission deadline 30 Apr 2027 | 1 articles | Viewed by 854 | Submission Open

Keywords: phytohormones; hormone signaling; abiotic stress responses; signaling crosstalk; transcriptional regulation; gene expression; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Nutrition and Food Science

edited by

Sze Ying Leong

and

Indrawati Oey

submission deadline 30 Apr 2027 | 1 articles | Viewed by 663 | Submission Open

Keywords: molecular nutrition; functional foods; bioactives; food matrix; nutrient bioavailability; digestion kinetics; gut microbiota; nutritional functionality; food structure–function relationships; food reformulation; food science

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cell and Epigenetic Regulation in Regenerative Medicine

edited by

Giuseppe Garroni

submission deadline 30 Apr 2027 | Viewed by 598 | Submission Open

Keywords: mesenchymal stem cells; regenerative medicine; stemness genes; stem cell differentiation; molecular regulation; gene expression; cell–environment interactions; conditioned medium; secreted factors; epigenetic modification

(This special issue belongs to the Section Molecular Biology)

Advances in Plant Transporters and Tolerance Proteins

edited by Kun Qiao

submission deadline 30 Apr 2027 | Viewed by 269 | Submission Open

Keywords: heavy metal; transporter; antioxidant; ornamental plants and horticulture; ion transport; phytoremediation; biofortification

(This special issue belongs to the Section Molecular Plant Sciences)

Forward in Vasculitis: Genetics and Beyond, 2nd Edition

edited by

Marija Jelusic

submission deadline 30 Apr 2027 | Viewed by 232 | Submission Open

Keywords: systemic vasculitides; ethiopathogenesis; risk factors; genetics; genomics; proteomics; transcriptomics; epigenetics; molecular pathways; novel therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biochemical Mechanisms of the Gut–Brain Axis: Microbial Metabolites, Barrier Integrity, and Neuroimmune Signaling

edited by

Sidharth Prasad Mishra

submission deadline 30 Apr 2027 | Viewed by 116 | Submission Open

Keywords: gut–brain axis; gut microbiota; microbial metabolites; intestinal barrier integrity; neuroimmune signaling; host-microbiome interactions; microbiome-brain communication; neuroinflammation; multi-omics; microbiome-based therapeutics

(This special issue belongs to the Section Molecular Biology)

Targeting Membrane Proteins: Structure, Function, and Dynamic Relationships

edited by Ki-Young Lee

submission deadline 30 Apr 2027 | Viewed by 101 | Submission Open

Keywords: membrane proteins; conformational dynamics; allosteric regulation; signal transduction; drug discovery; cryo-electron microscopy; nuclear magnetic resonance spectroscopy; artificial intelligence; membrane mimetics

(This special issue belongs to the Section Molecular Biology)

Advanced Research on Functional Genomics and Genome Editing in Plant

edited by

Rushil Ramesh Mandlik

submission deadline 30 Apr 2027 | Submission Open

Keywords: CRISPR/Cas; genome editing; functional genomics; plant biotechnology; gene regulation; base editing; prime editing; gene overexpression; multi-omics; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Evolution of the Vertebrate Immune System

edited by

Pierre Pontarotti

submission deadline 30 May 2027 | 1 articles | Viewed by 1356 | Submission Open

Keywords: immune system; molecular evolution; V (D) J recombination; RAG transposon; comparative genomics

(This special issue belongs to the Section Molecular Biology)

Agronomic Regulation of Crop Environmental Adaptation and Grain Safety: Physiological and Molecular Mechanisms

edited by

Ligeng Jiang

and

Sun Yujun

submission deadline 30 May 2027 | Viewed by 22 | Submission Open

Keywords: agronomic management; environmental adaptation; molecular regulation; physiological and biochemical mechanisms; crop quality formation; plant-soil-microbe interactions; heavy metal detoxification; nitrogen-use efficiency; photosynthetic efficiency

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology on Environmental Microorganisms

edited by

Mariusz Cycoń

submission deadline 31 May 2027 | 3 articles | Viewed by 1835 | Submission Open

Keywords: environmental microbiology; metagenomics; microbial interactions; phage–host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology

(This special issue belongs to the Section Molecular Microbiology)

Advanced Drug Delivery Systems: From Nanocarrier Design to Translation

edited by

Krishna Jadhav

and

Satish Rojekar

submission deadline 31 May 2027 | Viewed by 119 | Submission Open

Keywords: nanocarriers; stimuli-responsive; targeted delivery; biocompatibility; scale-up; nanomedicine

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms Linking Environmental Pollutant Exposure to Human Health and Development

edited by Agnieszka Ścibior and

Juan Llopis

submission deadline 31 May 2027 | Viewed by 75 | Submission Open

Keywords: environmental pollutants; molecular toxicology; developmental toxicology; particulate matter; metals and metalloids; pesticides; persistent organic pollutants; PFAS; environmental pharmaceuticals; microplastics; nanoplastics; mixture toxicity; adverse outcome pathways; human biomonitoring; toxicokinetics; oxidative stress; genotoxicity; epigenetics; endocrine disruption; neurodevelopment; human health risk assessment

(This special issue belongs to the Section Molecular Toxicology)

Functional Polymeric Biomaterials: From Molecular Engineering to Biomedical Applications

edited by

Joanna Rydz

Marta Musioł

, Khadar Duale and

Barbara Zawidlak-Węgrzyńska

submission deadline 1 Jun 2027 | Viewed by 45 | Submission Open

Keywords: polymeric biomaterials; biodegradable polymers; molecular design; AI-driven materials design; structure–property relationships; biomolecule–material interactions; biocompatibility; drug delivery systems; tissue engineering; regenerative medicine

(This special issue belongs to the Section Materials Science)

The Chitosan Biomaterials: Advances and Challenges, 3rd Edition

edited by

Lacramioara Popa

Mihaela Violeta Ghica

and Cristina Elena Dinu-Pirvu

submission deadline 20 Jun 2027 | 1 articles | Viewed by 1601 | Submission Open

Keywords: chitosan; chitosan biomaterials; chitosan derivatives; drug delivery; wound healing; tissue regeneration; dentistry; smart biomaterials

(This special issue belongs to the Section Materials Science)

Molecular Progression of Genome-Related Diseases: 2nd Edition

edited by

Salvatore Saccone

submission deadline 25 Jun 2027 | 6 articles | Viewed by 22293 | Submission Open

Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health

(This special issue belongs to the Section Molecular Genetics and Genomics)

Effects of Bioactive Compounds in Cardiovascular and Neurological Diseases

edited by

Paul-Mihai Boarescu

submission deadline 30 Jun 2027 | 1 articles | Viewed by 2746 | Submission Open

Keywords: inflammation; oxidative stress; bioactive compounds; cardiovascular diseases; neurological diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Targeting Oxidative Stress: New Insights into Disease Pathogenesis, Emerging Preventive Strategies and Novel Therapeutic Approaches

edited by Fabio Vivarelli and

Donatella Canistro

submission deadline 30 Jun 2027 | 2 articles | Viewed by 2360 | Submission Open

Keywords: metabolism; inflammation; oxidative stress; diabetes; natural oxidative stress modulators; novel preventive/therapeutic strategies; ageing; cardiovascular diseases; regenerative medicine; neurodegeneration; environmental exposure; cancer

(This special issue belongs to the Section Molecular Biology)

From Molecular Understanding to Ecological Significance: Understanding Marine Reproductive Biology

edited by

Zohaib Noor

submission deadline 30 Jun 2027 | Viewed by 437 | Submission Open

Keywords: reproductive biology; gametogenesis; bivalves reproduction; biodiversity; endocrine regulation; gametogenesis; molecular signaling; genomics; fertilization; population dynamics; ecological resilience

(This special issue belongs to the Section Molecular Biology)

Sex and Gender Medicine: New Horizons in Human Health and Disease

edited by

Alessandra Carè

, Eliana Ferroni and

Elena Ortona

submission deadline 30 Jun 2027 | 1 articles | Viewed by 319 | Submission Open

Keywords: sex differences; gender medicine; personalized medicine; health inequities; intersectionality; precision health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanoparticle Toxicity: Beyond Chemical Composition—the Critical Role of Physicochemical Properties

edited by

Karen Khachatryan

submission deadline 31 Jul 2027 | 1 articles | Viewed by 1210 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; physicochemical properties; risk assessment; reactive oxygen species (ROS); protein corona; cellular uptake; regulatory science; safe-by-design

(This special issue belongs to the Section Molecular Toxicology)

Selected Papers from the HSG-2025 Conference

edited by

Marsel Kabilov

submission deadline 31 Jul 2027 | 1 articles | Viewed by 866 | Submission Open

Keywords: metagenomics; genomics; metabarcoding; next-generation sequencing; transcriptomics; translatomics; NGS data analysis

(This special issue belongs to the Section Molecular Genetics and Genomics)

Machine Learning in RNA and Chromatin Dynamics

edited by Haopeng Yu

submission deadline 31 Jul 2027 | Viewed by 556 | Submission Open

Keywords: machine learning; chromatin architecture; RNA dynamics; genomic foundation models; computational biology

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Aging: Genetics, Epigenetics and Biomolecular Interventions

edited by

Shin Murakami

submission deadline 31 Jul 2027 | Viewed by 33 | Submission Open

Keywords: aging; biomarkers; bioactive nutrients; centenarians; life-extending interventions; exercise; red wine; stress resistance and metabolism; age-related diseases

(This special issue belongs to the Section Molecular Biology)

Exploring Molecular Mechanisms of Neuroendocrine Tumors

edited by

Luigi Pio Guerrera

and Michele Ghidini

submission deadline 31 Jul 2027 | Viewed by 20 | Submission Open

Keywords: rare tumours; neuroendocrine neoplasms; translational research; gut microbiome; liquid biopsy; novel targets; VHL1; predictive biomarkers; tumour microenvironment

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Bioinformatics Analysis of Single Cell and Spatial Multi-Omics

edited by Fahong Yu

submission deadline 20 Aug 2027 | 1 articles | Viewed by 1269 | Submission Open

Keywords: bioinformatics; single-cell omics; spatial multi-omics; matabolomics; genomics; transcriptomics; proteomics; next-generation sequencing techniques

(This special issue belongs to the Section Molecular Informatics)

Molecular Mechanisms, Biomarkers, and Translational Research in Stroke and Neurotrauma

edited by Kang-Ho Choi

submission deadline 30 Aug 2027 | Viewed by 12 | Submission Open

Keywords: stroke; cerebrovascular disease; endovascular thrombectomy; prognostic biomarkers; molecular pathophysiology; neurovascular imaging; lipidomic metabolites; experimental neurology; clinical trial methodologies; novel therapeutic approaches

(This special issue belongs to the Section Molecular Neurobiology)

Research on Genomics of Crop Stress Tolerance

edited by

Xi Zhu

submission deadline 31 Aug 2027 | 2 articles | Viewed by 944 | Submission Open

Keywords: crop stress tolerance; genomic research; molecular mechanisms; multi-omics approaches; epigenetic modifications

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Targeting in Nanoparticle Systems: Precision Therapy, Detoxification, and Environmental Remediation

edited by

Adelina-Gabriela Niculescu

and Dan Eduard Mihəiescu

submission deadline 31 Aug 2027 | Viewed by 422 | Submission Open

Keywords: nanoparticles; nanocomposites; molecular targeting; stimuli-responsive materials; magnetic nanoparticles; surface functionalization; precision therapy; detoxification; decontamination; environmental remediation

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Molecular and Cellular Biology in Neuroscience

edited by

Keigo Kohara

submission deadline 31 Aug 2027 | Viewed by 178 | Submission Open

Keywords: molecular neuroscience; cellular neurobiology; imaging; synaptic plasticity; optogenetics; brain visualization; signal transduction; developmental molecular and cellular biology in neuroscience; neurological disorders

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 2951-3000 on page 60 of 60.

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