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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research on the Antioxidant, Anti-Inflammatory, and Antibacterial Activities of Natural Products

edited by

Carmen Lizette Del Toro Sánchez

and

Ariadna Thalia Bernal-Mercado

submission deadline 28 Feb 2027 | Viewed by 344 | Submission Open

Keywords: natural bioactive compounds; antioxidant mechanisms; anti-inflammatory pathways; antibacterial activity; agro-industrial byproducts; molecular docking; structure–activity relationship (SAR); omics technologies; drug delivery systems; nanobiotechnology; bioavailability

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nutrition for Muscle Health and Metabolism

edited by

Hira Shakoor

submission deadline 28 Feb 2027 | Viewed by 339 | Submission Open

Keywords: nutrition; skeletal muscle; muscle metabolism; mitochondrial function; insulin sensitivity; myokines; metabolic health; metabolic disease

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Mechanisms Underlying the Pathogenesis and Treatment of Gastrointestinal Disorders

edited by

Andrzej Pławski

submission deadline 28 Feb 2027 | Viewed by 336 | Submission Open

Keywords: gastrointestinal disorders; molecular mechanisms; diagnosis; treatment; precision medicine; biomarkers; gastrointestinal cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Dementia and Application of Biomarkers

edited by

Teresa Juárez-Cedillo

submission deadline 28 Feb 2027 | Viewed by 334 | Submission Open

Keywords: Alzheimer's; diagnosis; biological marker; protein; therapeutic target

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology of Preeclampsia and Gestational Diabetes: Shared Molecular Mechanisms in Pregnancy-Related Disorders

edited by Tamara Nikolic Turnic

submission deadline 28 Feb 2027 | Viewed by 334 | Submission Open

Keywords: preeclampsia; molecular mechanism; mechanism of preventive/curative strategies; placenta dysfunction

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Spinal Cord Injury: A Comprehensive Approach to Pathophysiology, Treatment, and Recovery

edited by Raúl Silva Garcia and Elisa García-Vences

submission deadline 28 Feb 2027 | Viewed by 330 | Submission Open

Keywords: spinal cord injury; neuroprotection; inflammation; therapy; pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Phenolic Compounds as Adjunct Therapy in Cardiometabolic Disorders

edited by

Dalia Marija Kopustinskiene

submission deadline 28 Feb 2027 | Viewed by 329 | Submission Open

Keywords: phenolic compounds; cardiovascular diseases; metabolism; diabetes; obesity; hypertension; mitochondria; oxidative stress; gut microbiota; inflammation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Plant Secondary Metabolites and Their Regulatory Mechanisms

edited by

Daniela Trono

submission deadline 28 Feb 2027 | Viewed by 324 | Submission Open

Keywords: secondary metabolites; plant growth and development; response to biotic and abiotic stresses; biosynthesis and degradation; gene and enzyme regulation; metabolic engineering; omics approaches

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Molecular Research of Supramolecular Polymers

edited by

Attila Bende

submission deadline 28 Feb 2027 | Viewed by 323 | Submission Open

Keywords: supramolecular polymers; supramolecular aggregates; molecular self-assemblies; photochemistry and photophysics of molecular materials

(This special issue belongs to the Section Materials Science)

Microbes in Obstetrics: Current Importance of Ascending Bacterial Infection (ABI)

edited by Alfredo Ovalle and Enrique Oyarzun

submission deadline 28 Feb 2027 | Viewed by 322 | Submission Open

Keywords: ascending bacterial infection (ABI); vaginal dysbiosis; spontaneous preterm birth (sPTB); group B streptococcus (GBS); fetal inflammatory response syndrome (FIRS); microbiomics; maternal immunology; cervical insufficiency

(This special issue belongs to the Section Molecular Microbiology)

Advances in Neuropharmacology: From Molecular Design to Preclinical Models

edited by

Jana Tchekalarova

and Miroslav A. Rangelov

submission deadline 28 Feb 2027 | Viewed by 318 | Submission Open

Keywords: neuropharmacology; drug discovery; molecular modeling; preclinical models

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Genetics of Arthritis

edited by

Bouchra Edderkaoui

submission deadline 28 Feb 2027 | Viewed by 316 | Submission Open

Keywords: arthritis; genetic susceptibility; genome-wide association studies; population genetics; genetic loci; epigenetics; gene-environmental interaction; polygenic risk scores; transcriptomics; single-cell sequencing; genomics; rare variants; polymorphisms; candidate genes; autoimmunity genetics; genetics of cartilage; degeneration, regeneration, and inflammatory pathways; genetic biomarkers; pharmacogenomics; functional genomics; precision medicine/ personalized treatments

(This special issue belongs to the Section Molecular Genetics and Genomics)

Vitamin D in Reproductive Disorders: Determinants, Metabolism, and Downstream Biological Mechanisms

edited by

Eugenia Mata-Greenwood

submission deadline 28 Feb 2027 | Viewed by 310 | Submission Open

Keywords: vitamin D; perinatal corticosteroids; placental insufficiency; intrauterine growth restriction; cortisol metabolism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Postharvest Biology

edited by Hua Zhang

submission deadline 28 Feb 2027 | Viewed by 307 | Submission Open

Keywords: postharvest biology; molecular regulation; plant hormone signaling; gas signaling molecules; ripening-related genes; transgenic technology; postharvest quality preservation

(This special issue belongs to the Section Molecular Plant Sciences)

Coordination Architectures for Next-Generation Chemical Sensors: Metal Complexes, Coordination Polymers and MOFs

edited by

Tamara Basova

and

Darya Klyamer

submission deadline 28 Feb 2027 | Viewed by 302 | Submission Open

Keywords: metal complexes; coordination polymers; MOFs

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Exploring Molecular Mechanisms of Lens Development and Growth

edited by

Michael L. Robinson

submission deadline 28 Feb 2027 | Viewed by 300 | Submission Open

Keywords: lens development; lens fiber cell differentiation; organelle degradation; transcriptional regulation; signal transduction; lens regeneration; chromatin remodeling; ocular development

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Treatments of Prostate Cancer

edited by

Sara Merler

submission deadline 28 Feb 2027 | Viewed by 299 | Submission Open

Keywords: prostate cancer; molecular mechanisms; tumor progression; androgen receptor signaling; genetic and epigenetic alterations; biomarkers; tumor microenvironment; therapeutic resistance; targeted therapies

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Biomarkers of Renal Injury: Bridging the Gap Between Micro-Environment Damage and Clinical Diagnosis

edited by Alexandre Braga Libório

submission deadline 28 Feb 2027 | Viewed by 292 | Submission Open

Keywords: renal injury; molecular biomarkers; AKI-CKD transition; regulated cell death; precision nephrology; renal microenvironment; epigenetics; tubulointerstitial fibrosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Extracellular Vesicles as Drivers of Cancer Therapy Resistance: Mechanistic Insights and Emerging Therapeutic Strategies

edited by Abraham Pedroza-Torres

submission deadline 28 Feb 2027 | Viewed by 291 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer resistance; tumor microenvironment; biomolecule transfer

(This special issue belongs to the Section Molecular Oncology)

Decoding Nuclear Receptor Networks: Dynamics, Microenvironment, and Therapeutic Intervention

edited by

Andreas Von Knethen

submission deadline 28 Feb 2027 | Viewed by 290 | Submission Open

Keywords: non-genomic mechanisms; interactome; agonists/antagonists; sequestration; pro- vs. anti-inflammatory; transcriptome; metabolome

(This special issue belongs to the Section Molecular Immunology)

Molecular Progression of Gut Microbiota—2nd Edition

edited by

Emina Pustijanac

submission deadline 28 Feb 2027 | Viewed by 289 | Submission Open

Keywords: gut microbiota; microbiome; differences in gut microflora; molecular techniques; gut microbiota’s role and composition; healthy state; dysbiosis

(This special issue belongs to the Section Molecular Microbiology)

Effects of Diets and Environmental Pollutants on the Intestine and Liver: A Molecular Perspective

edited by

Aneta Sokal-Dembowska

submission deadline 28 Feb 2027 | Viewed by 287 | Submission Open

Keywords: gut–liver axis; diet; environmental pollutants; molecular mechanisms; gut microbiota; intestinal barrier; liver disease; inflammation; oxidative stress; epigenetics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Biomedical and Tissue Engineering Strategies to Cross the Blood–Brain Barrier for Next-Generation Treatments Against Neurodegenerative Diseases, 2nd Edition

edited by Livia La Barbera

submission deadline 28 Feb 2027 | Viewed by 279 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer’s disease; CNS; blood–brain barrier; drug delivery systems; nanocarriers; nanomedicine; tissue engineering; theranostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Protein Inhibition and Metabolism

edited by Song Wang

submission deadline 28 Feb 2027 | Viewed by 275 | Submission Open

Keywords: protein inhibition; metabolism; computational chemistry; molecular modeling; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Non-Mammalian Models in Toxicology Research on Environmental Pollutants

edited by

Ida Ferrandino

and

Giovanni Scillitani

submission deadline 28 Feb 2027 | Viewed by 268 | Submission Open

Keywords: environment; pollution; pollutants; contaminants; non-mammalian models; animals; toxicology; invertebrates; lower vertebrates

(This special issue belongs to the Section Molecular Toxicology)

Backend Databases in Pharmacogenomics and Genome Informatics

edited by Alireza Tafazoli

submission deadline 28 Feb 2027 | Viewed by 267 | Submission Open

Keywords: pharmacogenomics; genome informatics; genomic databases; variant interpretation; pharmacogene nomenclature; genotype-to-phenotype translation; clinical decision support; application programming interfaces; FAIR genomic data

(This special issue belongs to the Section Molecular Informatics)

Innovative Advances in Cancer Therapy Through Nano-Based Systems

edited by

Lenuţa-Maria Şuta

and

Claudia Geanina Watz

submission deadline 28 Feb 2027 | Viewed by 266 | Submission Open

Keywords: nano-enabled delivery systems; innovative nanomaterials; smart nanocarriers; cancer nanotherapy; anti-tumorigenic activity

(This special issue belongs to the Section Molecular Nanoscience)

Recent Advances in Cancer Immunotherapy Research

edited by

Luigi Pasini

submission deadline 28 Feb 2027 | Viewed by 265 | Submission Open

Keywords: immunotherapy; CAR T-Cell therapy; mRNA cancer vaccines; ICIs; TIL therapy; nanotechnology; antibody discovery; drug discovery; tumor microenvironment; microbiome modulation; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

Obesity and Its Associated Diseases: Molecular and Metabolic Pathways

edited by Verónica J. Miksztowicz

submission deadline 28 Feb 2027 | Viewed by 262 | Submission Open

Keywords: obesity; dietary patterns; metabolic pathways; adipose tissue dysfunction; chronic low-grade inflammation; insulin resistance; mitochondrial dysfunction; oxidative stress; adipokine signaling; inter-organ crosstalk

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Screening and Identification of Crop Abiotic Stress Tolerance Functional Genes: 2nd Edition

edited by

Liezhao Liu

submission deadline 28 Feb 2027 | Viewed by 260 | Submission Open

Keywords: plant; abiotic stress; gene; identification; function

(This special issue belongs to the Section Molecular Plant Sciences)

Cytokine Signaling in the Bone Marrow Niche: Implications for Hematopoiesis in Health and Disease

edited by

Melinda Varney

submission deadline 28 Feb 2027 | Viewed by 259 | Submission Open

Keywords: bone marrow niche; bone marrow cytokine signaling; hematopoiesis; hematopoietic stem cells; microenvironmental regulation; inflammatory signaling; hematologic disease

(This special issue belongs to the Section Molecular Immunology)

Computational Strategies for Antiviral Drug Discovery: QSAR, In Silico Modeling and Data-Driven Approaches

edited by

Mohammed Salah

submission deadline 28 Feb 2027 | Viewed by 259 | Submission Open

Keywords: antiviral drug discovery; viral diseases; computational drug design; in silico modeling; quantitative structure–activity relationship (QSAR); molecular modeling; molecular dynamics simulations; virtual screening; machine learning in drug discovery; bioactive compounds; computer-aided drug design (CADD)

(This special issue belongs to the Section Molecular Informatics)

Cancer Genomics: Key Advances in the Precision Era

edited by

Maria Samara

submission deadline 28 Feb 2027 | Viewed by 259 | Submission Open

Keywords: cancer genomics; next-generation sequencing; artificial intelligence; computational biology; liquid biopsy; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Toxicity and Therapeutic Potential of Hymenoptera Venoms

edited by

Xesús Feás

submission deadline 28 Feb 2027 | Viewed by 259 | Submission Open

Keywords: hymenoptera venom; molecular toxicology; allergenicity; venom peptides; therapeutic applications; drug discovery; envenomation; bioactive compounds

(This special issue belongs to the Section Molecular Toxicology)

Emerging Advances in Fluorescent Biosensors

edited by

Xiaolong Liu

submission deadline 28 Feb 2027 | Viewed by 257 | Submission Open

Keywords: single molecule imaging; fluorescent probes; super-resolution imaging

(This special issue belongs to the Section Molecular Biophysics)

Pharmacological Mechanisms of Natural Products: Biological Targets and Clinical Perspectives

edited by Damião Pergentino De Sousa

submission deadline 28 Feb 2027 | Viewed by 254 | Submission Open

Keywords: central nervous system; inflammation; cancer; infection; metabolism; essential oils; medicinal plants; alkaloids; flavonoids; natural products

(This special issue belongs to the Section Molecular Pharmacology)

Bringing New Molecular Insights into Neurodegenerative Diseases

edited by

Daniela Vecchio

submission deadline 28 Feb 2027 | Viewed by 251 | Submission Open

Keywords: neurodegeneration; pathogenic mechanisms; biomarkers; neuroimaging; artificial intelligence; protein aggregation; neuroinflammation; genetics and epigenetics; multi-omics; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Oral Cancer

edited by Junichi Tanuma

submission deadline 28 Feb 2027 | Viewed by 250 | Submission Open

Keywords: oral squamous cell carcinoma; tumor microenvironment; immune regulation; molecular signaling; metabolic reprogramming; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Molecular Regulation of Cancer Stem Cells: Signaling Networks, Metabolism, and Therapeutic Targeting

edited by Shanchun Guo

submission deadline 28 Feb 2027 | Viewed by 247 | Submission Open

Keywords: glioma; cancer stem cell; drug design; small molecular; diagnosis; prognosis; pathology

(This special issue belongs to the Section Molecular Oncology)

Molecular Nutrition and Functional Foods: Mechanisms of Metabolic Health Regulation

edited by

Eugene Chang

submission deadline 28 Feb 2027 | Viewed by 243 | Submission Open

Keywords: nutrients; bioactive food components; functional food; signaling pathways; metabolism; metabolic regulation; nutrigenomics; gut microbiota; inflammation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Epigenetic Mechanism in Gynecologic Oncology

edited by

Aneta Słabuszewska-Jóźwiak

submission deadline 28 Feb 2027 | Viewed by 236 | Submission Open

Keywords: epigenetics; cancer; molecular medicine; molecular mechanism; gene expression; cancer pathogenesis

(This special issue belongs to the Section Molecular Oncology)

Photoreceptors and the Optic Nerve

edited by Ruth Estela Rosenstein and Damian Dorfman

submission deadline 28 Feb 2027 | Viewed by 225 | Submission Open

Keywords: photoreceptors; optic nerve; neurodegeneration; neuroprotection; experimental models; retina

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Biopolymers: From Natural Origins to Biomedical Hydrogels and Drug Delivery Systems

edited by Abril Fonseca García

submission deadline 28 Feb 2027 | Viewed by 222 | Submission Open

Keywords: polysaccharides; biomaterials; hydrogels; biomedicine; food packaging; water treatment

(This special issue belongs to the Section Macromolecules)

Molecular Research in Cerebral Ischemia: From Microglial States to Angiogenic Resilience

edited by Abdullah Ahmad

submission deadline 28 Feb 2027 | Viewed by 213 | Submission Open

Keywords: cerebral ischemia; neurovascular unit; microglial plasticity; angiogenic resilience; microvascular regeneration; innate immune activation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Allergen Prediction, Characterization, and Immunoinformatics

edited by

Katarina Smiljanić

submission deadline 28 Feb 2027 | Viewed by 212 | Submission Open

Keywords: allergen prediction; allergen characterization; proteomics; immunoinformatics; environmental allergens; food allergens; IgE epitopes; molecular docking; machine learning; mass spectrometry

(This special issue belongs to the Section Molecular Immunology)

Latest Research in Biomarkers of Neurodegenerative Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 28 Feb 2027 | Viewed by 205 | Submission Open

Keywords: biomarkers; neurodegenerative diseases; amyloid; oxidative stress; neuroinflammation; aging

(This special issue belongs to the Section Molecular Neurobiology)

Current Issues in Natural Product Bioactivity and Drug Discovery

edited by

Bey-Hing Goh

Jun-Ho Kim

and Pei Lou Wong

submission deadline 28 Feb 2027 | Viewed by 202 | Submission Open

Keywords: natural products; drug discovery; bioprospecting; pharmacology; multi-omics; molecular biology; bioactivity; advanced screening; emerging technologies; artificial intelligence

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Composites of Cellulose and Cellulose Derivatives: Engineering and Applications

edited by

Omar A. El Seoud

submission deadline 28 Feb 2027 | Viewed by 198 | Submission Open

Keywords: cellulose composites: engineering and applications; composites of cellulose esters: engineering and applications; composites of cellulose ethers: engineering and applications; molecular interactions within cellulose and its derivatives; molecular interactions within composites of cellulose and its derivatives

(This special issue belongs to the Section Macromolecules)

New Insights into Retinal Degenerative Diseases

edited by

Deokho Lee

submission deadline 28 Feb 2027 | Viewed by 187 | Submission Open

Keywords: age-related macular degeneration; ischemic retinopathy; glaucoma; diabetic retinopathy; polyphenols; mitochondria; choroidal neovascularization; vitamins; oxidative stress; cell therapy; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Impact of Signaling and Function of Individual Incretin Receptors on the Pharmacology of Incretin-Based Drugs

edited by

Anastasios Lymperopoulos

submission deadline 28 Feb 2027 | Viewed by 173 | Submission Open

Keywords: drug development; incretin; signal transduction; obesity; metabolism; G protein-coupled receptor; receptor pharmacology; translational medicine

(This special issue belongs to the Section Molecular Pharmacology)

Displaying special issue 2651-2700 on page 54 of 62.

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