International Journal of Molecular Sciences

Research Progress in Food Packaging Materials

edited by

submission deadline 30 Sep 2026 | 1 articles | Viewed by 571 | Submission Open

Keywords: molecular design; intermolecular interactions; structure–property relationships; bio-based polymers; controlled release systems; active packaging; sustainable materials

(This special issue belongs to the Section Materials Science)

CAR-T Cell Biology and Clinical Translation

edited by

Antonio Pérez Martínez

and

Daniel Ka Leung Cheuk

submission deadline 30 Sep 2026 | Viewed by 563 | Submission Open

Keywords: chimeric antigen receptor (CAR) T cells; gene engineering; genome editing; T‑cell exhaustion; tumor microenvironment; cytokine release syndrome (CRS); ICANS (immune effector cell–associated neurotoxicity syndrome); allogeneic CAR‑T cells; dual‑targeting CAR‑T cells; point‑of‑care manufacturing

(This special issue belongs to the Section Molecular Immunology)

Protein Structure, Dynamics and Interactions

edited by

Gyula Batta

and

Orsolya Tőke

submission deadline 30 Sep 2026 | 1 articles | Viewed by 563 | Submission Open

Keywords: protein; structure; folding; dynamics; interactions; NMR; X-ray crystallography; cryo-electron microscopy; AlphaFold; in silico

(This special issue belongs to the Section Macromolecules)

Emerging Challenges for Renal Health-Biomarkers and Vulnerability to Xenobiotics

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 30 Sep 2026 | 1 articles | Viewed by 550 | Submission Open

Keywords: xenobiotics; nephrotoxicity; mechanisms of renal damage; molecular pathways; acute kidney injury; chronic kidney disease; novel renal biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Antimicrobial Resistance in Cancers

edited by Nicola Silvestris and Massimo Andreoni

submission deadline 30 Sep 2026 | Viewed by 545 | Submission Open

Keywords: antimicrobial resistance; host–pathogen interaction; immune dysfunction; immunosuppression; infection; biomarker; novel antimicrobials; cancer; frail patient

(This special issue belongs to the Section Molecular Oncology)

A Window to the Brain: From Retinal Cellular and Soluble Biomarkers Towards Neurodegeneration

edited by

Bijorn Omar Balzamino

,

Rosanna Squitti

and

Alessandra Micera

submission deadline 30 Sep 2026 | Viewed by 516 | Submission Open

Keywords: retinal signaling; oxidative stress; retinal neurodegeneration; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Bioactive Lipids in Health and Disease: From Bench to Translational Insights

edited by

Claudio Bernal

submission deadline 30 Sep 2026 | 1 articles | Viewed by 514 | Submission Open

Keywords: functional lipids; lipids properties; fatty acids; lipid signaling; lipidomics; precision nutrition; cardiometabolic disease; inflammation; translational research

(This special issue belongs to the Section Bioactives and Nutraceuticals)

T Cell Receptor (TCR) Signaling at the Crossroads of Immunity, Tolerance, and Disease

edited by Amar Singh

submission deadline 30 Sep 2026 | Viewed by 514 | Submission Open

Keywords: T cell receptor (TCR) signaling; immune tolerance; effector T cell differentiation; regulatory T cells (Tregs, Tr1); T cell heterogeneity; metabolic reprogramming; T cell memory and exhaustion; TCR repertoire analysis; autoimmunity and inflammation; TCR-based immunotherapy; CAR-T cells

(This special issue belongs to the Section Molecular Immunology)

Diverse Biomolecular Probes in the Development of Single-Molecule Biosensors

edited by

Kevin D. Belfield

and

Xiaohan Chen

submission deadline 30 Sep 2026 | Viewed by 512 | Submission Open

Keywords: biomolecular probes; single-molecule method; biosensors; diseases diagnosis; biomarkers; nanotechnology

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of Endocrine-Disrupting Chemicals in Reproductive Toxicity

edited by

Dragana Samardžija Nenadov

submission deadline 30 Sep 2026 | 1 articles | Viewed by 511 | Submission Open

Keywords: endocrine-disrupting chemicals (EDCs); reproductive toxicity; steroidogenesis; molecular mechanisms; intracellular signaling; hormone receptors; reproductive health

(This special issue belongs to the Section Molecular Toxicology)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 506 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Transformation and Associated Isotope Kinetics of Halogenated Organic Pollutants in the Environment and Living Organisms

edited by Chenchen Huang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 505 | Submission Open

Keywords: halogenated organic pollutants; compound-specific isotope analysis; isotope fractionation; source apportionment; transformation discrimination; mechanism elucidation; biotic and abiotic transformation; transformation kinetics and pathways; environmental fate

(This special issue belongs to the Section Biochemistry)

Cellular and Molecular Mechanisms of Biological Interactions with Carbon-Based Materials

edited by Ângela Almeida and

Francesca Coppola

submission deadline 30 Sep 2026 | 1 articles | Viewed by 502 | Submission Open

Keywords: carbon (nano)materials; (nano)toxicology; biomaterial interactions; biosensors; remediation; risk assessment

(This special issue belongs to the Section Molecular Nanoscience)

Emerging Cardiovascular Drugs and Nutraceuticals: Mechanistic Insights, Translational Research and Clinical Impacts

edited by Pietro Mazzeo,

Vincenzo Vestuto

and Elena Mele

submission deadline 30 Sep 2026 | Viewed by 500 | Submission Open

Keywords: cardiovascular disease; drug mechanisms; nutraceuticals; precision medicine; multi-omics approaches

(This special issue belongs to the Section Molecular Pharmacology)

Next-Generation Sequencing in Cancer: Genomics, Diagnostics and Therapeutics

edited by Adam Szpechciński and Magdalena Pelc

submission deadline 30 Sep 2026 | 1 articles | Viewed by 496 | Submission Open

Keywords: next-generation sequencing (massively parallel sequencing); whole-genome sequencing (WGS); whole-exome sequencing (WES); RNA sequencing (RNA-seq); single-cell sequencing (SCS); germline and somatic mutations; gene rearrangements (fusions); epigenetics; molecular diagnostics; bioinformatics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Sep 2026 | Viewed by 495 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Valorization of Agri-Food Wastes: Extraction, Characterization and Functional Applications of Bioactive Compounds

edited by Pittaya Chaikham

submission deadline 30 Sep 2026 | Viewed by 494 | Submission Open

Keywords: agri-food waste valorization; bioactive compounds; functional foods; green extraction; food sustainability; plant-based ingredients; antioxidants; circular economy; probiotics; food processing

(This special issue belongs to the Section Biochemistry)

Recent Advances in Electrochemical-Related Materials: 2nd Edition

edited by Celia García-Hernandez

submission deadline 30 Sep 2026 | 1 articles | Viewed by 490 | Submission Open

Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications

(This special issue belongs to the Section Materials Science)

Omega-6 and Omega-3 Fatty Acid Imbalance: Roles in Human Health and Pathogenesis of Diseases

edited by

Jing X. Kang

submission deadline 30 Sep 2026 | Viewed by 486 | Submission Open

Keywords: omega-6/omega-3 ratio; omega-6 fatty acids; omega-3 fatty acids; omega-6/omega-3 imbalance; lipid metabolism; inflammation; chronic diseases; cardiovascular disease; cancer; metabolic syndrome; neurodegenerative diseases; autoimmune diseases; nutritional interventions; polyunsaturated fatty acids (PUFAs); molecular mechanisms; disease pathogenesis; disease management; health promotion

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathogenic Escherichia coli: Cellular Biology, Mechanisms of Pathogenesis, Therapeutic Approaches and Strategies for Disease Intervention

edited by

Jorge Goldstein

submission deadline 30 Sep 2026 | Viewed by 459 | Submission Open

Keywords: enterohemorrhagic E. coli; EHEC; Shiga toxin-producing E. coli; STEC; HUS; inflammation; kidney; blood; brain; pathogenesis; antibodies; extraintestinal pathogenic E. coli; E. coli pathotypes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Patient-Derived iPSC Models in Chronic Disease Research

edited by

Valentina Parra

submission deadline 30 Sep 2026 | Viewed by 451 | Submission Open

Keywords: induced pluripotent stem cells; patient-derived iPSCs; chronic diseases; disease modeling; molecular mechanisms; stem cell differentiation; gene editing; organoids; personalized medicine; multi-omics

(This special issue belongs to the Section Molecular Biology)

Research on Immune Mechanisms in Kidney Disease

edited by Niels Olsen Saraiva Câmara

submission deadline 30 Sep 2026 | Viewed by 449 | Submission Open

Keywords: kidney disease; molecular sensors; kidney metabolism; immunity; AKI to CKD transition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Molecular Pathways and Therapeutic Strategies in Atherosclerotic Cardiovascular Disease

edited by

Elisabeta Badila

and Catalin Adrian Buzea

submission deadline 30 Sep 2026 | Viewed by 434 | Submission Open

Keywords: atherogenesis; vascular inflammation; immune modulation; lipid metabolism; clonal hematopoiesis (CHIP); endothelial dysfunction; plaque instability; epigenetic regulation; molecular signaling pathways; precision cardiovascular medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Computational Intelligence and Algorithmic Advances in Genome Editing

edited by

Anderson Rodrigues dos Santos

submission deadline 30 Sep 2026 | 1 articles | Viewed by 428 | Submission Open

Keywords: CRISPR/cas systems; genome engineering; bioinformatics; gRNA design; off-target prediction; machine learning; structural modeling; molecular informatics; DNA repair pathways

(This special issue belongs to the Section Molecular Informatics)

Advances in Molecular Plant Physiology and Genomic Breeding of Cereals

edited by

Abdullah Shalmani

submission deadline 30 Sep 2026 | Viewed by 428 | Submission Open

Keywords: cereals; molecular physiology; genomic breeding; stress tolerance; functional genomics; genome editing; QTL mapping; multiomics; genotype–environment interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Gut Microbiota-Mediated Drug Efficacy and Toxicity

edited by

Jin-Yi Wan

submission deadline 30 Sep 2026 | Viewed by 419 | Submission Open

Keywords: gut microbiota; pharmacomicrobiomics; drug metabolism; drug toxicity; drug efficacy; xenobiotic biotransformation; precision medicine; cancer immunotherapy; fecal microbiota transplantation; host–microbiome interactions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Metabolomics in Cancer: From Biomarkers to Therapeutic Insights

edited by Filipa Amaro,

Paula Guedes de Pinho

and

Joana Pinto

submission deadline 30 Sep 2026 | Viewed by 412 | Submission Open

Keywords: cancer metabolomics; metabolic reprogramming; biomarker discovery; precision oncology; machine learning; clinical data integration; translational cancer research

(This special issue belongs to the Section Molecular Oncology)

Genome-Wide Association Studies of Complex Diseases and Related Endophenotypes and Biomarkers

edited by M. Ilyas Kamboh

submission deadline 30 Sep 2026 | Viewed by 406 | Submission Open

Keywords: genome-wide association studies; complex diseases; endophenotypes; biomarkers; rare variants; copy number variants; diverse populations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Inflammatory Bowel Disease and Cardiometabolic Comorbidities: Molecular Mechanisms and Therapeutic Perspectives

edited by

Dimitrios Patoulias

and

Christos Mademlis

submission deadline 30 Sep 2026 | Viewed by 402 | Submission Open

Keywords: cardiovascular–kidney–metabolic syndrome; diabetes; obesity; cardiovascular disease; inflammatory bowel disease; Crohn’s disease; ulcerative colitis; inflammation; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Integrating Multi-Omics Approaches in Fish Immunology to Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 400 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Novel Insights into Endothelial Cell Biology

edited by

Takato Hara

and

Toshiyuki Kaji

submission deadline 30 Sep 2026 | Viewed by 386 | Submission Open

Keywords: endothelial cell heterogeneity; mechanotransduction; endothelial–immune interactions; endothelial senescence; vascular barrier regulation; extracellular vesicles; angiogenesis and vascular remodeling; endothelial metabolism; endothelial regulation of the fibrinolytic system

(This special issue belongs to the Section Molecular Biology)

Molecular Interplay: Natural Antioxidants as Modulators of Redox Homeostasis

edited by

Giovanni Pratelli

and

Daniela Carlisi

submission deadline 30 Sep 2026 | Viewed by 381 | Submission Open

Keywords: natural antioxidants; oxidative stress; chronic diseases; molecular mechanisms; cancer; neurodegenerative diseases; metabolic disorders; redox biology; omics; precision medicine

(This special issue belongs to the Section Molecular Biology)

Genetic Diversity, Founder Effects, and Migration in Neurodegeneration: Molecular and Population Perspectives

edited by

Dasiel Oscar Borroto-Escuela

submission deadline 30 Sep 2026 | Viewed by 380 | Submission Open

Keywords: neurodegeneration; population genetics; founder effects; genetic diversity; migration and disease risk; spinocerebellar ataxia; Alzheimer’s disease; Parkinson’s disease; genetic epidemiology; underrepresented populations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Determinants of Cardiovascular Diseases

edited by

Susan Darroudi

submission deadline 30 Sep 2026 | Viewed by 376 | Submission Open

Keywords: atherosclerosis; hypertension; diabetes; dyslipidemia; endothelial dysfunction; vascular remodeling; inflammation and oxidative stress; mitochondrial dysfunction; molecular diagnostics; heart function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Therapeutic Antibody Engineering

edited by

Chatchai Tayapiwatana

submission deadline 30 Sep 2026 | Viewed by 374 | Submission Open

Keywords: therapeutic antibodies; bispecific antibodies; antibody-drug conjugates (ADCs); nanobodies; AI-driven drug design; Fc engineering; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

DNA Damage, DNA Repair, and Cancer, 3rd Edition

edited by

Kazuhiko Kuwahara

submission deadline 30 Sep 2026 | 1 articles | Viewed by 368 | Submission Open

Keywords: DNA-damage response; DNA repair molecules; genome instability; cellular senescence; animal models; DNA damage; DNA repair and cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Pituitary Neuroendocrine Tumors: From Growth Control to Plasticity and Evolutionary Pathogenesis

edited by Ana Lucía De Paul and Liliana del Valle Sosa

submission deadline 30 Sep 2026 | Viewed by 360 | Submission Open

Keywords: tumor heterogeneity; tumor biomarkers; transcriptomics; molecular neuroscience; clinical treatment; pathogenesis; pituitary neuroendocrine tumors; neuroendocrine tumors; nonfunctional; PIT1; pituitary adenoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Studies of Cartilage Deformation

edited by

Kazuo Yudoh

submission deadline 30 Sep 2026 | Viewed by 359 | Submission Open

Keywords: osteoarthritis; chondrocyte; mitochondria function; mechanical stress; oxidative stress; cartilage metabolism

(This special issue belongs to the Section Molecular Biology)

Role of Bifunctional Antibodies in Human Cancer

edited by

Alessandro Canella

submission deadline 30 Sep 2026 | Viewed by 358 | Submission Open

Keywords: bispecific antibodies; tumor immune microenvironment (TIME); cancer immunotherapy; tumor associated antigens; biomarker discovery; T cell engagers (BiTEs, TriTEs, TriKEs); dual affinity retargeting antibodies (DARTs); Fc engineering and FcγR modulation; tumor associated antigen (TAA) avidity optimization; immune reprogramming; bispecific antibody pharmacokinetics and biodistribution; antibody–drug conjugate (ADC) hybrid formats; bifunctional antibodies

(This special issue belongs to the Section Molecular Oncology)

Current Trends in Nanophotonics and Molecular-Scale Light Control

edited by Mitradeep Sarkar

submission deadline 30 Sep 2026 | Viewed by 347 | Submission Open

Keywords: nanophotonics; light–matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics

(This special issue belongs to the Section Molecular Nanoscience)

Procoagulant Platelets in Vascular Disease and Beyond

edited by

Paresh P. Kulkarni

submission deadline 30 Sep 2026 | Viewed by 341 | Submission Open

Keywords: procoagulant platelets; thrombosis; hemostasis; coagulation; bleeding; vascular disease; cancer; cardiometabolic syndrome; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Future Perspective and Challenge of Nanomaterials

edited by

Antreas Afantitis

submission deadline 30 Sep 2026 | Viewed by 335 | Submission Open

Keywords: nanomaterial; nanoinformatics; materials informatics; functional material; molecular dynamics

(This special issue belongs to the Section Molecular Nanoscience)

Effects of Radiation on Biomolecules and Cells: Mechanisms, Responses, and Biological Implications

edited by

Sachin Gulati

submission deadline 30 Sep 2026 | Viewed by 333 | Submission Open

Keywords: radiation biology; biomolecular damage; cellular responses; DNA damage and repair; oxidative stress; radioprotection; radiotherapy; dosimetry; molecular mechanisms; radiation-induced toxicity

(This special issue belongs to the Section Molecular Biology)

Inherited Endocrine Tumors: Genetics, Genomics, and Molecular Pathogenesis

edited by Vito Guarnieri,

Alberto Falchetti

and Antonio Stefano Salcuni

submission deadline 30 Sep 2026 | Viewed by 332 | Submission Open

Keywords: parathyroid; adrenal; pancreas; thyroid; pituitary

(This special issue belongs to the Section Molecular Genetics and Genomics)

Regulatory T Cells and Immune Tolerance: From Nobel Discoveries to Clinical Breakthroughs

edited by Raquel López-Mejías

submission deadline 30 Sep 2026 | Viewed by 328 | Submission Open

Keywords: regulatory T cells (Tregs); immune tolerance; FOXP3 gene; therapies; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Biological Effects and Toxicity of Nanomaterials

edited by Lucyna Kapka-Skrzypczak

submission deadline 30 Sep 2026 | Viewed by 324 | Submission Open

Keywords: nanotoxicology; nanomaterials; biological effects; cytotoxicity; oxidative stress; inflammation; genotoxicity; immunotoxicity; risk assessment; nanosafety; nanomedicine; environmental health; in vitro models; in vivo studies

(This special issue belongs to the Section Molecular Nanoscience)

TRIM Family Proteins and Beyond: Molecular Mechanisms in Tissue Homeostasis and Disease

edited by

Chuanxi Cai

submission deadline 30 Sep 2026 | Viewed by 320 | Submission Open

Keywords: TRIM family proteins; E3 ubiquitin ligases; protein homeostasis; autophagy and selective autophagy; innate immunity and antiviral defense; signal transduction; post-translational modifications; phase separation; tissue homeostasis; cancer biology; heart failure; neurodegeneration; inflammation and immunity; molecular mechanisms of disease; biomarkers and therapeutic targets

(This special issue belongs to the Section Molecular Biology)

Advances in Cell Signaling Pathways and Signal Transduction, 2nd Edition

edited by

Susumu Ohya

and Katsuhiko Muraki

submission deadline 30 Sep 2026 | Viewed by 312 | Submission Open

Keywords: signaling pathway; signal transduction; cell biology; signal transduction; cell communication; cell signaling

(This special issue belongs to the Section Biochemistry)

Targeted Therapies and Chemoresistance in Gastrointestinal Cancers

edited by Zheng Chen

submission deadline 30 Sep 2026 | Viewed by 311 | Submission Open

Keywords: gastrointestinal cancer; targeted therapy; chemoresistance; drug resistance; precision medicine; molecular biomarkers; signal transduction; tumor microenvironment; immunotherapy; novel therapeutics

(This special issue belongs to the Section Molecular Oncology)

Deep Learning for Bioinformatics and Biomedicine

edited by

Burak Tasci

submission deadline 30 Sep 2026 | Viewed by 310 | Submission Open

Keywords: bioinformatics; deep learning; genomics (DNA); histopathology; multi-omics; molecular biomarkers; drug discovery; computational pathology; systems biology; precision medicine

(This special issue belongs to the Section Molecular Informatics)

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