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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Biomathematics, Computational Biology, and Bioengineering

edited by

Grzegorz Matyszczak

submission deadline 20 Apr 2026 | 5 articles | Viewed by 3462 | Submission Open

Keywords: biomathematics; machine learning; artificial intelligence; data science; systems biology; reaction– diffusion systems; nonlinear dynamics; bioreactors; biochemical reaction engineering

(This special issue belongs to the Section Molecular Informatics)

Chronic Liver Disease and Hepatocellular Carcinoma—2nd Edition

edited by

Daniela Gabbia

and Sara Carpi

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3431 | Submission Open

Keywords: hepatocellular carcinoma; NAFLD/NASH; viral hepatitis; autoimmune liver disease; immunotherapy; biomarker

(This special issue belongs to the Section Molecular Oncology)

Molecular Research on Endothelial Cell Injury and Repair

edited by

Eleni Gavriilaki

and

Panagiota Anyfanti

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3420 | Submission Open

Keywords: endothelial injury; endothelial repair; endotheliopathies; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Roles of Mesenchymal Stem/Stromal Cells in Tumor Therapies

edited by Francesco Agostini

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3394 | Submission Open

Keywords: mesenchymal stem cells; tumor; cancer patients; ex vivo cell modification; cell and gene therapy; targeted drug delivery; homing; migration; current regulatory guidelines; MSC therapeutic potential

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Skin Health and Disease

edited by

Mihaela Pertea

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3358 | Submission Open

Keywords: wound healing; molecular research in skin lesions; dermatologic surgery; cosmetic surgery; exosomes: new molecular targets of diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Breeding of Plants: From CRISPR/Cas9 to Transcriptomics and MABc

edited by

Kwon-Kyoo Kang

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3303 | Submission Open

Keywords: CRISPR/Cas9; transcriptomics; marker-assisted breeding; genome editing; plant genetics; gene expression; plant genomics; quantitative trait loci (QTL); crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Research on Mitochondrial Genetics and Epigenetics

edited by Arianna Montanari

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3296 | Submission Open

Keywords: mitochondrial DNA dynamics; retrograde regulation; epigenetic modulators; mitochondrial diseases; cellular homeostasis

(This special issue belongs to the Section Molecular Biology)

Developmental and Reproductive Toxicology

edited by

Hyun-Jung Park

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3253 | Submission Open

Keywords: spermatogenesis; mouse models; reproduction biology; assisted reproductive technology; cell signaling; cellular biology; developmental biology

(This special issue belongs to the Section Molecular Biology)

Molecular Characterization and Applications of Nanomaterials in Nanomedicine and Cancer Therapy

edited by

Costica Caizer

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3177 | Submission Open

Keywords: nanomaterials (preparation methods; characterization techniques; properties); theoretical studies of nanomaterials and computational simulations; biocompatibility and biofunctionalization; applications in nanomedicine; applications in cancer therapy; drug delivery; nanoparticle imaging; magnetic resonance imaging (MRI); contrast agents; nanotheranostics

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Signatures in Autism Spectrum Disorders

edited by

Nikolay Mehterov

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3173 | Submission Open

Keywords: epigenetics; ncRNA; mRNA; cytokines; mitochondria; inflammation; autism

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Neuroinflammation and Brain Aging

edited by

Stephen C. Bondy

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3149 | Submission Open

Keywords: neurotoxicology; aging; Alzheimer's disease; neurodegenerative diseases; inflammatory

(This special issue belongs to the Section Molecular Toxicology)

Sarcomas: From Molecular Insights to Personalized Therapies

edited by

Hye Jin You

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3088 | Submission Open

Keywords: soft tissue sarcoma; biomarkers; molecular mechanisms; experimental models; clinical factors associated with sarcoma development

(This special issue belongs to the Section Molecular Oncology)

Bone and Cartilage Injury and Repair: Molecular Aspects

edited by Silvia María Díaz-Prado

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3069 | Submission Open

Keywords: bone and cartilage repair; regenerative medicine; inflammation and immune response; stem cell therapy; extracellular matrix remodeling; biomaterials; drug delivery systems; therapeutic targets; biomarkers

(This special issue belongs to the Section Molecular Biology)

New Insights and Discoveries in the Pathogenesis, Diagnosis and Therapy of Neuromuscular Diseases

edited by

Dimitrios Kanakis

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3044 | Submission Open

Keywords: neuromuscular diseases; autophagy; mitochondrial dysfunction; molecular genetics; blood-based biomarkers; antisense oligonucleotides; monoclonal antibodies

(This special issue belongs to the Section Molecular Neurobiology)

Inflammatory Bowel Disease: Pathogenesis and Novel Therapeutic Approaches

edited by Francisco Giner

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3029 | Submission Open

Keywords: coeliac disease; microscopic colitis; Crohn’ s disease; ulcerative colitis; microbiota; biological therapies; refractory disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fungal Pathogen-Host Interactions

edited by Patricia Albuquerque

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3021 | Submission Open

Keywords: medical mycology; host– microbe interactions; macrophages; dendritic cells; neutrophils

(This special issue belongs to the Section Molecular Microbiology)

Synthetic Chemistry in Drug Discovery

edited by Kathiravan Suppan

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3008 | Submission Open

Keywords: late-stage functionalization; AI-driven synthesis; drug discovery; synthetic chemistry; transition metal catalysis

(This special issue belongs to the Section Molecular Pharmacology)

Natural Compounds in Cancer Therapy: Molecular Mechanisms and Translational Potential

edited by

Gregory Christodoulidis

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2949 | Submission Open

Keywords: natural compounds; cancer research; oxidative stress

(This special issue belongs to the Section Molecular Oncology)

Microbiota’s Role in Respiratory Disorders and Diseases

edited by

Ioannis Alexandros Charitos

and Mauro Carone

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2948 | Submission Open

Keywords: microbiota; microbiome; metabolome; transcriptome; microbiota gut/lung axis; microbiota gut/oral axis; respiratory disorders; respiratory diseases; respiratory rehabilitation

(This special issue belongs to the Section Molecular Microbiology)

Mitochondria and Energy Metabolism Reprogramming in Diseases

edited by

Nadège Bellance

submission deadline 20 Apr 2026 | 3 articles | Viewed by 2899 | Submission Open

Keywords: mitochondrial dysfunctions; energy metabolism; pathophysiological mechanisms; therapeutic targets; physiology of organelle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Radiobiology—New Advances

edited by

Marco Calvaruso

and

Luigi Minafra

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2856 | Submission Open

Keywords: radiobiology; radiotherapy; radiosensitizing agents; radioresistance; DNA damage; FLASH radiotherapy; particle therapy

(This special issue belongs to the Section Molecular Biology)

Molecular Research in Triple-Negative Breast Cancer: 2nd Edition

edited by

Yong-Moon Lee

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2843 | Submission Open

Keywords: triple negative breast cancer; lymph node metastasis; PMP22; prediction model using deep learning

(This special issue belongs to the Section Molecular Oncology)

Molecular and Genomic Aspects of Viral Pathogens

edited by

Joanna Dąbrowska

submission deadline 20 Apr 2026 | 3 articles | Viewed by 2820 | Submission Open

Keywords: viral pathogens; genetic and molecular mechanisms; viral infection; viral replication; host interaction

(This special issue belongs to the Section Molecular Microbiology)

Advanced Molecular Research in Cardiology and Treatment Approaches

edited by Ludger Hauck

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2781 | Submission Open

Keywords: TAp63; EzH2; histone methyltransferase; cardiomyocyte proliferation; myocardial infarction; heart regeneration; heart repair; epigenetic regulation; cardiac regeneration; Skp2-p27KIP1 pathway

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Treatment of Chronic Kidney Disease

edited by Xinming Chen

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2765 | Submission Open

Keywords: diabetes; cardiovascular diseases; nephrology; diabetic nephropathy

(This special issue belongs to the Section Molecular Biology)

Research on Luminescent Materials and Their Luminescence Mechanism

edited by

María Teresa Colomer

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2739 | Submission Open

Keywords: luminescence; molecular/ionic level; mechanism

(This special issue belongs to the Section Materials Science)

COVID-19: Molecular Research and Novel Therapy

edited by

Mihaela Chivu-Economescu

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2693 | Submission Open

Keywords: SARS-CoV-2; virus-host interaction; immune response; antiviral agents; vaccines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Endocannabinoid System in Reward- and Addiction-Related Neuroplasticity

edited by

Francisco Navarrete-Rueda

and

María S. García Gutiérrez

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2645 | Submission Open

Keywords: endocannabinoid system; neuroplasticity; reward; addiction; biomarker; therapeutic approach

(This special issue belongs to the Section Molecular Neurobiology)

Peptide and Protein Drugs Against Infectious Diseases and Allergic Diseases

edited by

Xiumin Wang

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2628 | Submission Open

Keywords: peptide and protein drugs; infectious diseases; allergic diseases; hormones; antimicrobial peptides; neuropeptides; cell-penetrating peptides; enzyme inhibitors; vaccines; antibodies

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Molecular Diagnostic Approaches for Neurodevelopmental Disorders: Applications and Future Perspectives

edited by

Barbara Lombardo

and Michele Pinelli

submission deadline 20 Apr 2026 | 3 articles | Viewed by 2583 | Submission Open

Keywords: neurodevelopmental disorders; array CGH; NGS

(This special issue belongs to the Section Molecular Neurobiology)

Explore Marine Biodiversity: Discover Insights from Genomics and Transcriptomics

edited by

Maria Sirakov

and Ambrosino Luca

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2556 | Submission Open

Keywords: comparative genomics; functional genomics; transcriptomics; gene expression; adaptation; population genomics; marine biodiversity; evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Current Trends in Redox Physiology Research

edited by Fotios Tekos

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2521 | Submission Open

Keywords: redox biology; oxidative stress; antioxidant mechanisms; redox signaling; cellular homeostasis; inflammation and redox; nutritional redox modulation; environmental toxicology and redox; mitochondrial dysfunction; oxidative stress biomarkers

(This special issue belongs to the Section Biochemistry)

Zebrafish Model for Neurological Research

edited by

Mattia Toni

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2519 | Submission Open

Keywords: zebrafish ; Danio rerio ; brain ; nervous system

(This special issue belongs to the Section Molecular Neurobiology)

New Insights and Research on Nutrition and Obesity

edited by

Giovanna Bermano

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2409 | Submission Open

Keywords: nutrition; obesity; malnutrition; overnutrition; molecular and cellular mechanisms; nutrient– gene interactions; metabolic disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Microbial Dynamics in Agroforestry for Resilience and Climate Adaptation

edited by

Amrita Chakraborty

and

Amit Roy

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2398 | Submission Open

Keywords: agroforestry; soil microbes; plant-microbe interactions; microbial influence; microbiomes; insect-microbe interactions; horizontal gene transfer

(This special issue belongs to the Section Molecular Plant Sciences)

Research Advances in Antibiotic Resistance

edited by

José Pascual Abad

and

Irma Marín

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2288 | Submission Open

Keywords: antibiotic resistance; resistant pathogenic microorganisms; One Health; prevalence of antibiotic-resistant microorganisms; multidrug resistance; antibiotic resistance levels; alternative anti-infectious strategies and compounds; antibiotic-resistant genes; mechanisms of antimicrobial resistance

(This special issue belongs to the Section Molecular Microbiology)

New Insights into Ubiquitination and Deubiquitination in Plants

edited by

Hongyong Fu

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2242 | Submission Open

Keywords: ubiquitin; E1; E2; E3; deubiquitination; proteolysis; plants

(This special issue belongs to the Section Biochemistry)

Genetic Prediction of Risk of Common Diseases

edited by

Grant Morahan

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2202 | Submission Open

Keywords: complex genetic diseases; cancer; heart disease; diabetes; dementia; polygenic risk score; genetic risk signatures

(This special issue belongs to the Section Molecular Genetics and Genomics)

Complex Interactions of Plants with Other Organisms: Particular Attention to Carnivorous and Parasitic Plants

edited by

Bartosz Płachno

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2191 | Submission Open

Keywords: carnivorous plants; parasitic plants; mycotrophic plants; hosts; phytochemistry; molecular biology; genome evolution; organ structure; cellular; genomic

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Microbial Genomics: Insights from Whole Genomes and Metagenomes

edited by

Marcos Quintela Baluja

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2134 | Submission Open

Keywords: microbial evolution; whole-genome sequencing; metagenomics; horizontal gene transfer; antimicrobial resistance; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biomarker Discovery in Oral Diseases: Integrating Connected Health and Digital Biomarkers for Advanced Diagnostics and Personalized Care

edited by

Shahnawaz Khijmatgar

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2132 | Submission Open

Keywords: oral diseases; biomarker; proteomics; metabolomics

(This special issue belongs to the Section Molecular Biology)

Cellular and Molecular Mechanisms in Inflammatory Bowel Disease

edited by Michael Bording-Jorgensen

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2128 | Submission Open

Keywords: IBD; cytokines; microbiome; Crohn’ s disease; ulcerative colitis; dysbiosis; mucosal immunity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology and the Genetic Breeding of Aquatic Animals: Breakthroughs and Challenges (2nd Edition)

edited by

Hongyan Xu

submission deadline 20 Apr 2026 | 4 articles | Viewed by 2115 | Submission Open

Keywords: transgenic; genetic breeding; omics; gene expression and regulation; aquatic animals

(This special issue belongs to the Section Molecular Biology)

Advancements in Molecular Science, Material Analysis, and Surface Treatments: Paving the Way for Future Technological Innovations

edited by

Fadoua El-Hajjaji

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2094 | Submission Open

Keywords: materials; surface treatments; corrosion; nanomaterials; coatings; molecular interactions; deposition

(This special issue belongs to the Section Materials Science)

Biochemical Advancements in Filler Technology and Their Impact on Tissue Engineering

edited by Samuel J. Lin

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2062 | Submission Open

Keywords: biochemical filler technology; tissue regeneration; bioactive materials; injectable scaffolds; molecular signaling in tissue engineering; biomaterials for soft tissue repair; filler– cell interactions; regenerative esthetics

(This special issue belongs to the Section Biochemistry)

Multiple Sclerosis: Molecular Basis and New Therapy

edited by Vito A. G. Ricigliano

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2057 | Submission Open

Keywords: multiple sclerosis; inflammation; microglia; Epstein– Barr virus; neurodegeneration; remyelination; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Accelerating Therapeutic Innovation: Advances in Computer-Aided Drug Discovery

edited by Pietro Delre and

Antonio Lavecchia

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2035 | Submission Open

Keywords: CADD; drug discovery; machine learning; virtual screening; drug-target interaction

(This special issue belongs to the Section Molecular Informatics)

Advancement of Understanding Alzheimer’s Disease Susceptibility and Novel Drug Targets

edited by Kunie Ando and Jean-Pierre Brion

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2011 | Submission Open

Keywords: Alzheimer’ s disease; neurodegenerative diseases; tau; amyloid; inflammation; disease modifying treatments; biomarkers; genetic variants; risk factors; mechanisms; protein– protein interactions; post-translational modifications

(This special issue belongs to the Section Molecular Neurobiology)

In Silico Approaches to Drug Design and Discovery

edited by

Alejandro Speck-Planche

submission deadline 20 Apr 2026 | 3 articles | Viewed by 1998 | Submission Open

Keywords: chemoinformatics; computational de novo design and generative AI methods; machine learning; deep learning; molecular modeling; pharmacophore modeling; molecular docking; molecular dynamics; QSAR/QSPR; virtual screening

(This special issue belongs to the Section Molecular Informatics)

Pathogenic Proteins in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Innovations

edited by

Minseok Song

and

Nidhi Puranik

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1984 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; frontotemporal dementia; lewy bodies dementia; amyloid β -protein; τ -protein; α -synuclein; TDP-43; neurotransmitter; neuropeptide; protein misfolding; protein Homeostasis; neuroinflammatory proteins; post-translational modifications

(This special issue belongs to the Section Molecular Neurobiology)

Displaying special issue 2451-2500 on page 50 of 67.

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