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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Technologies in Musculoskeletal Research: From Molecular Mechanisms to Translational Innovation

edited by

Javad Tavakoli

submission deadline 30 Nov 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: musculoskeletal tissue; cell mechanobiology; biofabrication; tissue regeneration; organ-on-a-chip; disease mechanism and screening; molecular and cellular diagnostics; AI and machine learning; omics technology; wearable technologies; implant technologies; biomarkers; predictive modelling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Diagnostic and Theragnostic Strategies in Brain Tumors

edited by Andrea Cimini and Laura Travascio

submission deadline 30 Nov 2026 | 1 articles | Viewed by 867 | Submission Open

Keywords: brain tumor; novel diagnostic and theragnostic approaches; neuro-oncology; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Emerging Molecular Mechanisms and Therapeutic Targets in Neurodegenerative Diseases and Brain Cancers

edited by

Subramanian Thangaleela

submission deadline 30 Nov 2026 | 1 articles | Viewed by 865 | Submission Open

Keywords: neuroinflammation; mitochondrial dysfunction; oxidative stress; advanced glycation end products; brain cancers; tumor microenvironment; nutraceutical interventions; plant bioactive molecules; miRNA therapies; oncogenic signaling pathways; blood–brain barrier in brain cancer; immunotherapy

(This special issue belongs to the Section Molecular Neurobiology)

Pediatric Diseases: From Molecular Mechanisms to Novel Therapeutic Strategies—2nd Edition

edited by

Elena Țarcă

submission deadline 30 Nov 2026 | 1 articles | Viewed by 838 | Submission Open

Keywords: congenital abnormalities; genetic disease; molecular mechanism; therapeutic agents; maternal and fetal medicine; pediatric diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Natural Products for Cancer

edited by Ana Carolina Gonçalves

submission deadline 30 Nov 2026 | Viewed by 805 | Submission Open

Keywords: natural products; plant-derived compounds; phenolic compounds; pharmacodynamics; pharma-cokinetics; antioxidant capacities; cancer; oxidative stress-related disorders; in vivo assays; in vitro assays; clinical assays; mechanisms of differentiation; tissue homeostasis

(This special issue belongs to the Section Molecular Oncology)

Modern Synthetic Pathways for Anticancer Drug Discovery

edited by

Łukasz Struk

submission deadline 30 Nov 2026 | 1 articles | Viewed by 797 | Submission Open

Keywords: new anticancer agents; bioactive molecules; drug design; drug synthesis; cancer therapy; medicinal chemistry

(This special issue belongs to the Section Molecular Oncology)

Bioactive Food Ingredients and Precision Nutrition: From Molecular Innovation to Clinical Relevance

edited by Lídia Pinheiro and

Célia Faustino

submission deadline 30 Nov 2026 | 1 articles | Viewed by 794 | Submission Open

Keywords: bioactive food ingredients; functional foods; nutraceuticals; precision nutrition; gut microbiota; delivery systems; omics technologies; AI in nutrition; personalized nutrition; immune modulation; neuroprotection

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Translational Advances in Melanoma Molecular Research

edited by

Marcela S. Villaverde

submission deadline 30 Nov 2026 | 1 articles | Viewed by 787 | Submission Open

Keywords: melanoma; molecular targets; resistance mechanism; future advances; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

Interaction Between Gut Microbiota and Food Bioactive Compounds

edited by

Abdul Mueed

submission deadline 30 Nov 2026 | 1 articles | Viewed by 783 | Submission Open

Keywords: gut microbiota; bioactive compounds; microbial metabolites; host–microbe interactions; molecular mechanisms; host signaling pathways; nutritional intervention; gut–diet–health axis; microbiota modulation; metagenomic/metatransxriptomics; prebiotics/probiotics/synbiotics; intestinal barrier function

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Plant Viruses: Discovery and Genetic Diversity

edited by

Xifeng Wang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 782 | Submission Open

Keywords: novel virus; discovery; high-throughput sequencing; diversity; population geneticss; evolutionary dynamic

(This special issue belongs to the Section Molecular Plant Sciences)

Zinc Signaling in Immunity

edited by

Lothar Rink

and

Inga Wessels

submission deadline 30 Nov 2026 | 1 articles | Viewed by 779 | Submission Open

Keywords: zinc signaling; zinc flux; zinc sparks; zinc wave; zinc transporter

(This special issue belongs to the Section Biochemistry)

Effects of Natural Bioactive Compounds on Cellular Responses

edited by

Amélia M. Silva

submission deadline 30 Nov 2026 | Viewed by 747 | Submission Open

Keywords: cellular targets; cell proliferation; cell death mechanisms; cell signalling; cytokines; vitamins; phytochemicals; venoms; peptides; pharmacological effect

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Design, Synthesis and Development of Anticancer Drugs Targeting the Tumor Microenvironment

edited by

Yoshihiro Uto

submission deadline 30 Nov 2026 | 1 articles | Viewed by 706 | Submission Open

Keywords: anticancer drugs; tumor microenvironment; in vivo model; cancer-associated fibroblast; tumor-associated macrophage; tumor hypoxia; tumor endothelial cells

(This special issue belongs to the Section Molecular Oncology)

Current Research on Choroid Plexus

edited by

Telma Quintela

submission deadline 30 Nov 2026 | 1 articles | Viewed by 680 | Submission Open

Keywords: choroid plexus; blood–cerebrospinal fluid barrier; cerebrospinal fluid; neurological diseases; brain homeostasis

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Skin Inflammation (2nd Edition)

edited by

Nabiha Yusuf

submission deadline 30 Nov 2026 | 1 articles | Viewed by 666 | Submission Open

Keywords: skin inflammation; molecular diagnosis; dermatitis; molecular pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

State-of-the-Art Molecular Pharmacology in Thailand

edited by

Sitthivut Charoensutthivarakul

submission deadline 30 Nov 2026 | 1 articles | Viewed by 664 | Submission Open

Keywords: molecular pharmacology; pharmacogenomics; bioactive natural products; drug discovery and design; molecular targets; precision medicine; signal transduction; cholangiocarcinoma therapeutics; neuropharmacology

(This special issue belongs to the Section Molecular Pharmacology)

Transcription Factors in Plant Gene Expression Regulation, 3rd Edition

edited by

Piotr Szymczyk

submission deadline 30 Nov 2026 | 1 articles | Viewed by 659 | Submission Open

Keywords: plant trans-factor ; cis-active sequence ; post-translational modification ; dimerization and oligomerization ; DNA modules

(This special issue belongs to the Section Molecular Plant Sciences)

Current Research on Skin Pigmentation and Photoaging

edited by Chang-Cheng Chang and

Tzong-Yuan Juang

submission deadline 30 Nov 2026 | Viewed by 636 | Submission Open

Keywords: skin pigmentation; melasma; photoaging; energy-based devices; skin rejuvenation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug-Induced Toxicity and Its Role in Disease Progression and Therapeutic Outcomes

edited by

Eugenia Gallardo

and

Tiago Rosado

submission deadline 30 Nov 2026 | Viewed by 629 | Submission Open

Keywords: drug-induced toxicity; drug-drug interactions; drug delivery systems; toxicity; disease

(This special issue belongs to the Section Molecular Toxicology)

Cancer Biomarkers: From Early Detection to Prognosis

edited by

Luís Lima

submission deadline 30 Nov 2026 | 1 articles | Viewed by 617 | Submission Open

Keywords: cancer biomarkers; early detection; prognosis; liquid biopsy; personalized oncology; multi-omics; translational research; predictive modeling

(This special issue belongs to the Section Molecular Oncology)

Transition-Metal-Based Nanoparticles: Synthesis, Properties and Applications

edited by Ramin Yousefi and

Sasan Rezaee

submission deadline 30 Nov 2026 | Viewed by 608 | Submission Open

Keywords: transition metal nanoparticles; synthesis; structure–property relationship; catalysis; photocatalysis; energy storage and conversion; biomedical applications; drug delivery; environmental remediation; plasmonics

(This special issue belongs to the Section Molecular Nanoscience)

Metabolic Diseases: From Molecular Mechanisms to Innovative Therapeutics

edited by

Aleksandra Szopa

and Anna D. Serefko

submission deadline 30 Nov 2026 | Viewed by 608 | Submission Open

Keywords: metabolic dysregulation; neuropsychiatric disorders; molecular crosstalk; neuroinflammation; mitochondrial dysfunction; neuroendocrine signaling; gut–brain axis; innovative therapeutic strategies; natural compounds; drug repurposing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Reproductive Genetics and Genomics in Crop Breeding

edited by

Alejandro Garcia Ramirez

submission deadline 30 Nov 2026 | 1 articles | Viewed by 603 | Submission Open

Keywords: genetics; heredity; agronomy; maize breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Amyotrophic Lateral Sclerosis

edited by

Viviana Greco

submission deadline 30 Nov 2026 | Viewed by 599 | Submission Open

Keywords: amyotrophic lateral sclerosis; proteomics; protein aggregation; mitochondria; neurodegeneration; RNA metabolism; oxidative stress; neuroinflammation; systems biology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Kidney Disease: From Biomarkers, Molecular Mechanisms to Targeted Therapy

edited by

Rusu Crina Claudia

submission deadline 30 Nov 2026 | Viewed by 598 | Submission Open

Keywords: kidney disease; biomarkers; molecular mechanisms; precision nephrology; chronic kidney disease; acute kidney injury; renal fibrosis; omics technologies; targeted therapy; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Interactions Between Bacteria and Viruses: Mechanisms and Pathogenic Insights

edited by Vasilis Petrakis

submission deadline 30 Nov 2026 | 1 articles | Viewed by 594 | Submission Open

Keywords: viral infections; HIV/AIDS; SARS-CoV-2; antibiotics; antimicrobial resistance; antiviral agents

(This special issue belongs to the Section Molecular Microbiology)

Neuroinflammation: Emerging Insights and Advances in Drug Development

edited by

Guya Diletta Marconi

Francesca Diomede

Jacopo Pizzicannella

and Paolo Gugliemi

submission deadline 30 Nov 2026 | Viewed by 577 | Submission Open

Keywords: neuroinflammation; drugs; neurodegenerative; Parkinson’s disease; Alzheimer’s disease; multiple scleroris; stroke

(This special issue belongs to the Section Molecular Neurobiology)

Research Advances in Vegetable Breeding and Genetics

edited by

Jinglei Wang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 569 | Submission Open

Keywords: vegetable; breeding; genetics; genomics; gene editing; marker-assisted selection; stress resistance; quality improvement; crop improvement; horticulture

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Research on Foodborne Pathogens and Biofilms

edited by

Arturo Ramirez-Peralta

submission deadline 30 Nov 2026 | 1 articles | Viewed by 569 | Submission Open

Keywords: foodborne pathogens; biofilms; food

(This special issue belongs to the Section Molecular Microbiology)

Roles of Erythrocytes in Human Health and Disease: 4th Edition

edited by

Francesco Misiti

submission deadline 30 Nov 2026 | Viewed by 561 | Submission Open

Keywords: erythrocytes; red blood cells; red blood functions; vascular function; blood bank storage

(This special issue belongs to the Section Molecular Biology)

Research of Aldo-Keto Reductases in Human Disease

edited by

Ping Zhu

and

Hao Luo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 552 | Submission Open

Keywords: aldo-keto reductase (AKR); protein engineering; AKR1B10; cancer biomarker; chemoresistance

(This special issue belongs to the Section Biochemistry)

Regulatory Networks and Gene Expression Pathways in Bacteria

edited by Miguel A. Ares

submission deadline 30 Nov 2026 | 1 articles | Viewed by 547 | Submission Open

Keywords: bacterial gene expression; regulatory networks; transcription factors; sigma factors; two-component systems; quorum sensing; non-coding RNAs; host–pathogen interactions; bacterial adaptation; RNA-seq

(This special issue belongs to the Section Molecular Microbiology)

Molecular Advances in Periodontitis

edited by Maja Miletić and

Natasa Nikolic-Jakoba

submission deadline 30 Nov 2026 | 1 articles | Viewed by 546 | Submission Open

Keywords: periodontitis; molecular mechanisms; inflammation; oral microbiome; multi-omics; biomarkers; cytokines; oxidative stress; immune regulation; tissue regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Quantum Chemical Intelligence: New Horizons of Molecular Structure and Reactivity

edited by

Mihai V. Putz

submission deadline 30 Nov 2026 | Viewed by 541 | Submission Open

Keywords: chemical bond and bonding; quantum states and measurements; chemical reactivity; valence models; complex coordination; reaction coordinates and paths; bio-nano-materials

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Hormetic Responses of Plants to Environmental Stress

edited by

Michael Moustakas

submission deadline 30 Nov 2026 | Viewed by 536 | Submission Open

Keywords: hormesis; environmental stress; dose–response; molecular mechanisms

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Nutrient Uptake and Utilization in Plants

edited by

Stella Karydogianni

submission deadline 30 Nov 2026 | Viewed by 524 | Submission Open

Keywords: agriculture and crop improvement; molecular and cellular mechanisms; nitrogen; nutrient efficiency; protein

(This special issue belongs to the Section Molecular Plant Sciences)

Bridging the Omics of Protein Landscape of Aging and Disease: New Insights and Opportunities

edited by

Fátima Milhano Santos

submission deadline 30 Nov 2026 | Viewed by 517 | Submission Open

Keywords: age-related disease; aging; biomarkers; chronic diseases; neurodegenerative diseases; ocular diseases; proteomics; kidney diseases

(This special issue belongs to the Section Molecular Biology)

Nutrition of Crustaceans: A Molecular Perspective

edited by

Cheng Chi

submission deadline 30 Nov 2026 | Viewed by 513 | Submission Open

Keywords: crustacean nutrition; molecular mechanisms; aquaculture; nutrient metabolism; reproduction

(This special issue belongs to the Section Molecular Biology)

Bioactive Peptides from Natural Sources: Pharmacological Effects, Recombinant Expression, Modification, Molecular Mechanisms, and Therapeutic Potential

edited by Linchun Shi

submission deadline 30 Nov 2026 | Viewed by 507 | Submission Open

Keywords: bioactive peptides; functional peptides; antimicrobial peptides; host-defense peptides; venom peptides; ribosomally synthesized and post-translationally modified peptides; peptide precursor gene families; comparative genomics; phylogeny; structure–activity relationship

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Peptides in Healthcare and Beyond: Emerging Roles in Skincare, Nutrition, Medicine, and Animal Health

edited by

Jiazhong Li

and Lijing Fang

submission deadline 30 Nov 2026 | Viewed by 506 | Submission Open

Keywords: peptides; efficacy; healthcare; skincare; nutrition; medicine; animal health

(This special issue belongs to the Section Biochemistry)

Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification

edited by

Ágnes Szepesi

submission deadline 30 Nov 2026 | Viewed by 499 | Submission Open

Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano–bio interactions; crop production; plant-based solutions; bio-corona

(This special issue belongs to the Section Molecular Plant Sciences)

Mitochondrial DNA and Its Multiple Functions in Health and Disease

edited by

Izinara Rosse

and Vanessa F. Gonçalves

submission deadline 30 Nov 2026 | Viewed by 492 | Submission Open

Keywords: mitochondrial DNA; mtDNA; mitochondrial genome sequencing; mitochondrial dysfunction; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into Probiotics and Prebiotics in Gut Health and Disease

edited by

Hikmate Abriouel

submission deadline 30 Nov 2026 | Viewed by 492 | Submission Open

Keywords: probiotics; prebiotics; gut microbiota; intestinal health; dysbiosis; host–microbe interactions; omics; gut–brain axis

(This special issue belongs to the Section Molecular Microbiology)

Advances in Research on Neurotransmitters (Second Edition)

edited by

Mario Manto

Hiroshi Mitoma

and Jing-Ning Zhu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 491 | Submission Open

Keywords: neurotransmitters; GABA; glutamate; monoamines; dopamine; serotonin; norepinephrine; neuropeptides; nitric oxide; neurosteroids; stress; neurotrophins; epigenetics; gut–brain axis

(This special issue belongs to the Section Molecular Neurobiology)

The Influence of Genetics on Lymphatic System Diseases

edited by

Tomomi Watanabe-Asaka

submission deadline 30 Nov 2026 | Viewed by 481 | Submission Open

Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Central Nervous System Inflammatory Demyelinating Diseases

edited by Yong Guo

submission deadline 30 Nov 2026 | Viewed by 479 | Submission Open

Keywords: central nervous system; autoimmune; demyelination; inflammation; multiple sclerosis; pathology

(This special issue belongs to the Section Molecular Neurobiology)

Molecular and Cellular Pathways Involved in Age-Related Musculoskeletal Disorders

edited by

Abhishek Chandra

and Neha Dole

submission deadline 30 Nov 2026 | Viewed by 478 | Submission Open

Keywords: musculoskeletal disorders; cellular senescence; aging; genetic mutations; oxidative stress; mitochondrial dysfunction; bone homeostasis

(This special issue belongs to the Section Molecular Biology)

Molecular, Cellular and Systems Research on Neuroanatomy, Brain Function and Its Impact on Human Behavior

edited by

Frank Schmitz

submission deadline 30 Nov 2026 | Viewed by 476 | Submission Open

Keywords: central nervous system; neuroanatomy; human behavior; nuclei; neuronal circuits; connectivity channels

(This special issue belongs to the Section Molecular Neurobiology)

Effects of the Environmental Conditions on Bacterial Growth and Functions

edited by

Fernanda Abreu

submission deadline 30 Nov 2026 | Viewed by 473 | Submission Open

Keywords: bacterial growth; growth conditions; gene expression; bioproducts; biofilm; resistance; population dynamics

(This special issue belongs to the Section Molecular Microbiology)

Molecular Engineering of Antimicrobial Agents: From Structure-Function Insights to Combinatorial Therapies

edited by Mingrui Liao

submission deadline 30 Nov 2026 | Viewed by 467 | Submission Open

Keywords: antimicrobial amphiphiles; antimicrobial resistance; structure–activity relationship; synergistic antimicrobial therapy; drug delivery systems

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 1201-1250 on page 25 of 63.

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