Exploring Natural Products for Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 80
Special Issue Editor
Interests: biological screening of natural products; phenolic compounds; HPLC; in vivo and in vitro studies; pharmacodynamics; pharmacokinetics; interactions between drugs and natural/food supplements; antioxidant and antimicrobial capacities; establishment of composition/bioactivity relationships and ailments
Special Issue Information
Dear Colleagues,
Cancer arises from disruptions in the molecular mechanisms that regulate cellular differentiation and tissue homeostasis. Alterations in oncogenes, tumour suppressor genes, and key signalling pathways drive uncontrolled proliferation, loss of differentiation, and invasive behaviour. Understanding these processes is essential for uncovering novel strategies for cancer prevention and therapy. Natural products and plant-derived compounds have attracted increasing attention due to their ability to modulate signalling cascades, epigenetic regulators, and cellular plasticity involved in tumour development. In addition, innovative delivery systems have been developed to enhance the efficacy, stability, and bioavailability of these bioactive molecules.
This Special Issue aims to collect original research articles and reviews addressing the role of differentiation and tissue homeostasis in cancer, with a particular focus on molecules of natural origin. Topics of interest include, but are not limited to, the following:
- Molecular mechanisms of differentiation and tissue homeostasis in cancer;
- Natural products and plant extracts as modulators of signalling pathways related to carcinogenesis;
- Differentiation-inducing and homeostasis-restoring agents for cancer therapy;
- Structure–activity relationships of natural molecules with anticancer activity;
- Novel technologies to improve the delivery and therapeutic potential of natural compounds.
Dr. Ana Carolina Gonçalves
Guest Editor
Manuscript Submission Information
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Keywords
- natural products
- plant-derived compounds
- phenolic compounds
- pharmacodynamics
- pharma-cokinetics
- antioxidant capacities
- cancer
- oxidative stress-related disorders
- in vivo assays
- in vitro assays
- clinical assays
- mechanisms of differentiation
- tissue homeostasis
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