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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research in Genetic Causes of Adult-Onset Disorders

edited by

Claudio Graziano

submission deadline 30 Nov 2025 | Viewed by 593 | Submission Open

Keywords: ADPKD; cardiomyopathy; CADASIL; amyloidosis; MODY; late-onset hearing impairment; penetrance; adult onset

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Aspects of Viral Pathogenesis: From Infection to Host Response

edited by

Quang Duy Trinh

submission deadline 30 Nov 2025 | 1 articles | Viewed by 592 | Submission Open

Keywords: viruses; viral pathogenesis; virus– host interaction; molecular virology; immunity; viral entry; viral replication; emerging viruses; infectious diseases; inflammation

(This special issue belongs to the Section Molecular Microbiology)

Antibiotics Science: Molecular Insights, Detection Strategies, Resistance Challenges and Interdisciplinary Applications

edited by

Lidia Magerusan

submission deadline 30 Nov 2025 | 2 articles | Viewed by 580 | Submission Open

Keywords: antibiotics; antibiotic molecular design and synthesis; antibiotic action mechanism; antibiotics resistance; environmental contamination; therapeutic monitoring; antibiotic sensing and detection; food and environmental safety

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Gastrointestinal Immunity: Balancing Homeostasis and Pathological States

edited by Mihai Danciu and Gabriel Becheanu

submission deadline 30 Nov 2025 | Viewed by 530 | Submission Open

Keywords: gastrointestinal immunity; mucosal barrier function; immune signaling pathways; gut microbiota; inflammatory bowel disease (IBD); colorectal cancer; cytokines and chemokines; immunopathology; targeted immunotherapy; biomarkers of gut inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Metal Nanoparticles

edited by

Emilia Konował

submission deadline 30 Nov 2025 | 1 articles | Viewed by 506 | Submission Open

Keywords: metal nanoparticles; molecular-level mechanisms; functional nanostructures; environmental nanotechnology; nanoparticle stability; catalysis; hybrid nanomaterials; bimetallic systems; ligand– nanoparticle interactions

(This special issue belongs to the Section Molecular Nanoscience)

Progress in Prevention and Treatment of Cardiovascular Diseases and Arrhythmias

edited by

Narcis Tribulova

submission deadline 30 Nov 2025 | 1 articles | Viewed by 446 | Submission Open

Keywords: translational research; novel animal models; novel treatment targets; pleiotropic drugs; harnessing of molecular H

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Toxicomicrobiomics: Exploring the Interplays Between Xenobiotics, Gut Microbiota, and Health

edited by

Ana López Moreno

and

Alicia Ruiz-Rodríguez

submission deadline 30 Nov 2025 | Viewed by 433 | Submission Open

Keywords: xenobiotics; gut microbiota; human health; harmful substances; toxic/mutagenic compounds

(This special issue belongs to the Section Molecular Microbiology)

Molecular-Scale Design and Applications of Food Packaging: Eco-Friendly Materials and Technologies

edited by

Xi Yu

and

Tian Zhong

submission deadline 30 Nov 2025 | Viewed by 406 | Submission Open

Keywords: sustainable packaging; biodegradable materials; smart packaging; active packaging; food safety; environmental impact

(This special issue belongs to the Section Materials Science)

New Perspectives in 3D Bioprinting

edited by Pamela Mozetic and

Alessio Bucciarelli

submission deadline 30 Nov 2025 | Viewed by 404 | Submission Open

Keywords: 3D bioprinting; regenerative medicine; pluripotent stem cells; disease modeling; precision medicine

(This special issue belongs to the Section Materials Science)

Genetic Considerations in the Evolving Treatment Landscape of Hormone-Sensitive and Hormone-Resistant Prostate Cancer

edited by

Pierre Tennstedt

submission deadline 30 Nov 2025 | Viewed by 399 | Submission Open

Keywords: prostate cancer; hormone-sensitive prostate cancer; HSPC; hormone-resistant prostate cancer; HRPC; metastasis; androgen deprivation therapy; docetaxel; androgen receptor axis-targeted therapy agents; ARAT; abiraterone; enzalutamide; apalutamide; talazoparib; genetic; biomarker; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Genomic and Proteomic Advances in Tracking Antibiotic Resistance Evolution

edited by

Vanessa Silva

submission deadline 30 Nov 2025 | Viewed by 346 | Submission Open

Keywords: antibiotic resistance; genomic; proteomic; one health

(This special issue belongs to the Section Molecular Biology)

Molecular Markers and Genetic Diversity in Plants

edited by Eugenija Kupčinskienė

submission deadline 30 Nov 2025 | Viewed by 318 | Submission Open

Keywords: plant populations; genetic diversity; molecular diversity; invasion; invasive alien species; pollution; climate change; habitat; conservation; endangered and rare species; DNA markers; molecular markers; sequencing

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Products on Neurological Diseases, Neuroinflammation and Neuropathic Pain

edited by Karin C. Calaza

submission deadline 30 Nov 2025 | Viewed by 293 | Submission Open

Keywords: natural products; neurological diseases; neuroinflammation; neuropathic pain; neuroprotection; anti-inflammatory compounds; pain modulation; plant-based therapies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Intercellular Communication and Signal Transduction

edited by

Dongki Yang

submission deadline 30 Nov 2025 | Viewed by 273 | Submission Open

Keywords: intercellular communication; signal transduction; extracellular vesicles (EVs); exosomes; tunneling nanotubes (TNTs); cytokines; hormonal signaling; neurotransmitters; mechanotransduction; immune signaling

(This special issue belongs to the Section Molecular Biology)

Research Progress on Photosensitizers and Photodynamic Therapy

edited by

Michal Heger

submission deadline 30 Nov 2025 | Viewed by 266 | Submission Open

Keywords: photodynamic therapy; photosensitizers; tumor microenvironment; nanotechnology; immunotherapy; targeted drug delivery; reactive oxygen species; hypoxia; combination therapy; molecular mechanisms

(This special issue belongs to the Section Biochemistry)

Regulation of Brown Adipose Function

edited by

Stephen F. Vatner

and

Shinsuke Nirengi

submission deadline 30 Nov 2025 | Viewed by 256 | Submission Open

Keywords: brown adipose tissue; metabolic disorders; thermogenesis; endocrine function; cellular signaling

(This special issue belongs to the Section Biochemistry)

Vitamin D and New Vitamin D Analogs

edited by

Yagamare Fall

submission deadline 30 Nov 2025 | Viewed by 249 | Submission Open

Keywords: vitamin D; vitamin D receptor; vitamin D analogs; synthesis; clinical applications; cancer; anti-proliferation; therapeutic target

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Research on Glycosylation

edited by

Yang Zhang

submission deadline 30 Nov 2025 | Viewed by 247 | Submission Open

Keywords: protein glycosylation; protein folding; cell signaling; immune regulation; glycoproteins

(This special issue belongs to the Section Biochemistry)

Stem Cell and Epigenetic Regulation in Regenerative Medicine

edited by

Giuseppe Garroni

submission deadline 30 Nov 2025 | Viewed by 228 | Submission Open

Keywords: mesenchymal stem cells; regenerative medicine; stemness genes; stem cell differentiation; molecular regulation; gene expression; cell– environment interactions; conditioned medium; secreted factors; epigenetic modification

(This special issue belongs to the Section Molecular Biology)

Strategies and Molecular Mechanisms to Enhance Outcomes in Orthobiologics

edited by Leonardo Oliveira

submission deadline 30 Nov 2025 | Viewed by 225 | Submission Open

Keywords: platelet-rich plasma; adipose-derived stem cells; microfragmented fat; nutrition; exercise; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lectins: Structural Diversity, Molecular Recognition and Emerging Applications

edited by

Patrícia Maria Guedes Paiva

submission deadline 30 Nov 2025 | Viewed by 222 | Submission Open

Keywords: lectins; structural diversity; molecular recognition; bioactivities; biomedical applications

(This special issue belongs to the Section Biochemistry)

The Application of Biomaterials in Bone Tissue Repair and Regeneration, 2nd Edition

edited by

Jacek Matys

submission deadline 30 Nov 2025 | Viewed by 220 | Submission Open

Keywords: allograft; autograft; autologous bone; bone; graft materials; mineral substitutes; regeneration

(This special issue belongs to the Section Materials Science)

Biomaterials for Bone Treatment, Replacement and Regeneration: Focus on Regeneration and Inflammation

edited by

Mike Barbeck

submission deadline 30 Nov 2025 | Viewed by 217 | Submission Open

Keywords: biomaterials ; bone substitute ; inflammation ; foreign body response ; bone regeneration

(This special issue belongs to the Section Materials Science)

Molecular Research on Ataxia

edited by

Jose Miguel Laffita-Mesa

submission deadline 30 Nov 2025 | Viewed by 211 | Submission Open

Keywords: ataxia; molecular mechanisms; repeat expansion disorders; gene discovery; biomarkers; RNA biology; protein aggregation; epigenetics; gene therapy; neurodegeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

DNA Repair, Genome Stability and Diseases

edited by Melike Caglayan

submission deadline 30 Nov 2025 | Viewed by 208 | Submission Open

Keywords: DNA damage; DNA repair; genomic stability; targeted therapy; biomarkers

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Design and Engineering of Carbon-Based Materials for Environmental Remediation and Bioenergy

edited by Hilda Elizabeth Reynel-Ávila

submission deadline 30 Nov 2025 | Viewed by 207 | Submission Open

Keywords: adsorption; catalysis; functionalization; molecular design; environmental; sustainable energy; tailoring

(This special issue belongs to the Section Materials Science)

Plant Extracts: Molecular Insights and Functional Potential

edited by Abdelaziz Yasri

submission deadline 30 Nov 2025 | Viewed by 205 | Submission Open

Keywords: plant extract; phytochemistry; plant secondary metabolites; plant extraction techniques; product valorization

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Contemporary Perspective of Cardio-Kidney Metabolic Syndrome: From Prevention to Management

edited by Alberto Palazzuoli,

Francesco Fedele

and

Anna Mattioli

submission deadline 30 Nov 2025 | Viewed by 202 | Submission Open

Keywords: cardiovascular risk factors; metabolic syndrome; chronic kidney disease; heart failure; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Pediatric Neuromuscular Disorders

edited by

Tai-Heng Chen

submission deadline 30 Nov 2025 | Viewed by 201 | Submission Open

Keywords: pediatric neuromuscular disorders; gene therapy; biomarkers; molecular pathophysiology; muscular dystrophy; motor neuron disease; translational medicine; neuromuscular therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Autoimmune Diseases and Rheumatology

edited by

Ching-Mao Chang

submission deadline 30 Nov 2025 | Viewed by 195 | Submission Open

Keywords: rheumatology; molecular immunology; autoimmune diseases; biomarkers; transcriptomics; proteomics; epigenetics; single-cell analysis; cytokine signaling; precision medicine; exosomes; microRNA; immune metabolism; fibroblast activation; translational research

(This special issue belongs to the Section Molecular Immunology)

Kidney Diseases: Molecular Research and Novel Therapies

edited by Niels Olsen Saraiva Camara

submission deadline 30 Nov 2025 | Viewed by 187 | Submission Open

Keywords: kidney disease; immunology and inflammation; zebrafish models; therapeutic targets; modern-era drivers of renal pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroinflammation: Emerging Insights and Advances in Drug Development

edited by

Guya Diletta Marconi

Francesca Diomede

Jacopo Pizzicannella

and Paolo Gugliemi

submission deadline 30 Nov 2025 | Viewed by 184 | Submission Open

Keywords: neuroinflammation; drugs; neurodegenerative; Parkinson’ s disease; Alzheimer’ s disease; multiple scleroris; stroke

(This special issue belongs to the Section Molecular Neurobiology)

Brain Stroke Across the Lifespan: Mechanisms, Models, Translational Advances and Impacts Beyond the Brain

edited by

Gabriele Deidda

submission deadline 30 Nov 2025 | 1 articles | Viewed by 183 | Submission Open

Keywords: stroke; brain; cerebral injury; post-stroke recovery; systemic physiology; models; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Exploring Recent Research on Natural Compounds: From Biosynthesis to Application

edited by

Nitin Mantri

submission deadline 30 Nov 2025 | Viewed by 182 | Submission Open

Keywords: proteins like antibodies and enzymes; small molecules; plant extracts; biosynthesis; nanodelivery; drug discovery

(This special issue belongs to the Section Biochemistry)

Gynecologic Oncology: Tumor Microenvironment and Novel Therapeutics

edited by

Carmela Ricciardelli

submission deadline 30 Nov 2025 | Viewed by 181 | Submission Open

Keywords: tumor microenvironment; peritoneal-cancer cell interactions; extracellular matrix; ascites; immune cells; cancer-associated fibroblasts; immunotherapy; novel therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Rheumatoid Arthritis: From Molecular Mechanism to Emerging Therapeutic Target

edited by Elisa Gremese and Costantino Pitzalis

submission deadline 30 Nov 2025 | Viewed by 179 | Submission Open

Keywords: rheumatoid arthritis; molecular mechanisms; emerging therapeutic targets; precision medicine; synovial tissue

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antimicrobial Nanoparticles: Mechanisms, Applications, and Future Directions

edited by

Carmen Curutiu

and

Alina Maria Holban

submission deadline 30 Nov 2025 | Viewed by 179 | Submission Open

Keywords: antimicrobial activity; nanoparticles; biofilm nano-modulators; antibiotic resistence; wastewater treatment; preservative properties of nanoparticles

(This special issue belongs to the Section Molecular Microbiology)

Kidney Disease: Molecular Insights and Emerging Therapies

edited by

Yaochun Zhang

submission deadline 30 Nov 2025 | Viewed by 176 | Submission Open

Keywords: kidney disease; molecular mechanism; precision medicine; translational nephrology; targeted molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Tau Protein Research

edited by

Taxiarchis Katsinelos

submission deadline 30 Nov 2025 | Viewed by 173 | Submission Open

Keywords: tau biology; disease model systems; protein aggregation; tauopathies; neurodegeneration; Alzheimer’ s disase; seeded aggregation; amyloid filaments; tau propagation; antibodies; targeted protein degradation; tau therapeutics

(This special issue belongs to the Section Molecular Biology)

Molecular Modeling in Pharmaceutical Sciences

edited by

Maciej Spiegel

submission deadline 30 Nov 2025 | Viewed by 171 | Submission Open

Keywords: molecular modeling; computer-aided drug design; molecular docking; drug discovery; quantum chemistry; molecular dynamics simulations; virtual screening; computational pharmacology; pharmacy; in silico methods

(This special issue belongs to the Section Molecular Pharmacology)

Recent Advances in Lipopolysaccharides

edited by

Satish Raina

and

Gracjana Klein

submission deadline 30 Nov 2025 | Viewed by 170 | Submission Open

Keywords: LPS structural diversity; lipid A; amino arabinose and phosphoethanolamine; TLR4; antibiotic resistance; Lpt transport system; phospholipids and fatty acids; cell envelope stress; lipid A acyltransferases

(This special issue belongs to the Section Molecular Biology)

Combined and Mixture Exposure Toxicology of Cancer

edited by

Alok Deoraj

and Quentin Felty

submission deadline 30 Nov 2025 | Viewed by 169 | Submission Open

Keywords: combined exposure; mixture exposure; toxicology of cancer; omics of cancer; AI in carcinogenesis; machine learning use in cancer; cancer biomarkers; pollutants of cancer; agrochemicals; endocrine-disruptive chemicals

(This special issue belongs to the Section Molecular Oncology)

Predict to Treat: Prognostic and Predictive Biomarkers in Breast Cancer

edited by

Fabio Puglisi

submission deadline 30 Nov 2025 | Viewed by 167 | Submission Open

Keywords: breast cancer; predictive biomarkers; prognostic biomarkers; precision oncology; treatment resistance; gene expression; liquid biopsy; immune microenvironment; targeted therapy; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Eukaryotic Cells Under Stress: Biochemical and Physiological Mechanisms of Resistance and Resilience

edited by

Bruno Hay Mele

and

Carmen Arena

submission deadline 30 Nov 2025 | Viewed by 167 | Submission Open

Keywords: cellular stress response; oxidative stress; bioactive compounds; ROS; DNA damage/repair; environmental stressors; molecular chaperones; antioxidant in human diseases

(This special issue belongs to the Section Molecular Biology)

New Horizons in Antiviral and Antibacterial Agent Discovery

edited by

Federica Dell’Annunziata

and

Veronica Folliero

submission deadline 30 Nov 2025 | 1 articles | Viewed by 165 | Submission Open

Keywords: antimicrobial resistance; multidrug-resistant infections; new antimicrobial drug development; natural and synthetic an-timicrobial agents; drug repurposing

(This special issue belongs to the Section Molecular Microbiology)

Stress Signaling and Horticultural Crops Quality Control

edited by

Weibiao Liao

and

Yanjie Xie

submission deadline 30 Nov 2025 | Viewed by 164 | Submission Open

Keywords: stress tolerance; molecular mechanisms; quality traits; redox regulation; postharvest physiology; signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms and Diagnostics in Hereditary Hemolytic Anemias

edited by Joan-Lluís Vives-Corrons

submission deadline 30 Nov 2025 | Viewed by 163 | Submission Open

Keywords: anemia; red blood cell erythropoiesis; membranopathies ; erythro enzymopathies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Small Molecules in Tissue Repair and Regeneration

edited by

Ildiko Bock-Marquette

submission deadline 30 Nov 2025 | Viewed by 163 | Submission Open

Keywords: small molecules; organ and tissue regeneration; development; aging

(This special issue belongs to the Section Molecular Biology)

Molecular Aspects of Diabetes and Its Complications

edited by

Giuseppe Murdolo

submission deadline 30 Nov 2025 | Viewed by 162 | Submission Open

Keywords: obesity; insulin resistance; type 2 diabetes; atherosclerosis; endothelial dysfunction; cardiovascular disease; peripheral artery disease; diabetic feet; diabetic micoangiopathy; diabetic neuropathy; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insight into Nematodes Management

edited by

Giada D'Errico

submission deadline 30 Nov 2025 | Viewed by 162 | Submission Open

Keywords: biological control; micro-organisms; molecular identification; biodiversity; climatic changes; soil nema-todes; cultural practices; host plant resistance; anaerobic soil disinfection; biofumigation

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 101-150 on page 3 of 66.

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