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New Horizons in Antiviral and Antibacterial Agent Discovery

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 14

Special Issue Editors


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Guest Editor
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84081 Baronissi, Italy
Interests: antibiotic resistance mechanisms; host–pathogen interactions; multidrug-resistant bacterial infections; novel antibacterial compounds; antiviral mechanisms and therapeutics; antimi-crobial compound–membrane interactions; nanomaterials in microbial pathogenesis; target identification for antimicrobial drug development
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84081 Baronissi, Italy
Interests: antibiotic resistance mechanisms; host–pathogen interactions; multidrug-resistant bacterial infections; novel antibacterial compounds; antiviral mechanisms and therapeutics; antimi-crobial compound–membrane interactions; nanomaterials in microbial pathogenesis; target identification for antimicrobial drug development
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The prevalence of antimicrobial-resistant bacteria and viruses poses a major threat to global public health and constitutes a silent pandemic. Multidrug-resistant (MDR) strains compromise the effectiveness of conventional therapies, making infections difficult to treat and leading to a risk of complications and mortality.The World Health Organization emphasizes the urgent need to invest in the development of new drugs and alternative therapeutic strategies. Given this scenario, the Special Issue “New Horizons in Antiviral and Antibacterial Agent Discovery” aims to collect scientific contributions to explore new frontiers in the fight against MDR minfections. The Special Issue focuses on innovative approaches for the identification and development of antiviral and antibacterial agents, with particular attention to the following:

  • Natural compounds, derived from sustainable extraction methods or green synthesis techniques, which represent a valuable and underutilized resource;
  • Synthetic molecules, rationally designed to overcome resistance mechanisms or to target novel biological pathways;
  • Repurposed drugs, already approved by the Food and Drug Administration for other therapeutic indications, but with potential antimicrobial activity to be rediscovered;
  • Innovative pharmacological strategies, including combination therapies, aimed at counteracting the spread of increasingly difficult-to-treat pathogens.

We invite the scientific community to contribute original research articles and reviews to this multidisciplinary Special Issue.

We would like to acknowledge Dr. Flora Salzano (Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy) for her participation as Guest Editor Assistant in the development of this Special Issue.

Dr. Federica Dell’Annunziata
Dr. Veronica Folliero
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • multidrug-resistant infections
  • new antimicrobial drug development
  • natural and synthetic an-timicrobial agents
  • drug repurposing

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Published Papers

This special issue is now open for submission.
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