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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Research on Plant Hormones Affecting Crop Yield and Fruit Quality

edited by

María Serrano

and

Daniel Valero

submission deadline 20 Dec 2025 | 1 articles | Viewed by 5232 | Submission Open

Keywords: auxins; gibberellins; citokynis; ethylene; yield; quality; antioxidant; storage

(This special issue belongs to the Section Molecular Plant Sciences)

Systemic Sclerosis: New Insight into Pathogenesis, Molecular and Immune Mechanisms

edited by

Przemysław Kotyla

submission deadline 20 Dec 2025 | 3 articles | Viewed by 5002 | Submission Open

Keywords: systemic sclerosis; autoimmunity; inflammation; fibrosis; pathophysiology and treatment; profibrotic signaling; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antifungal Drug Discovery: Progresses, Challenges, Opportunities, 2nd Edition

edited by

Bernhard Biersack

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4970 | Submission Open

Keywords: antifungal drugs; fungal infections; drug design; drug discovery; targeted therapy; drug resistance; fungal drug targets; neglected tropical diseases

(This special issue belongs to the Section Molecular Pharmacology)

Antimicrobial Nanomaterials: Approaches, Strategies and Applications

edited by

Andrea Bernardos

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4777 | Submission Open

Keywords: nanotechnology; biocides; antimicrobials; controlled release; drug delivery; antimicrobial agents; antimicrobial resistance; infection; nanoparticles

(This special issue belongs to the Section Materials Science)

Data Science in Cancer Genomics and Precision Medicine: 2nd Edition

edited by

Apostolos Zaravinos

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4716 | Submission Open

Keywords: cancer genomics; big data; tumor immunology; translational oncology; precision medicine; next-generation sequencing; omics; cancer genomic datasets

(This special issue belongs to the Section Molecular Genetics and Genomics)

Biochemistry and Molecular Biology of Coronaviruses

edited by

Shu-Qun Liu

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4658 | Submission Open

Keywords: SARS-CoV; MERS-CoV; COVID-19; RNA viruses; infection; antivirals; vaccines; therapeutics; host-virus interactions

(This special issue belongs to the Section Molecular Microbiology)

Biomarkers for Cardiovascular Risk Prediction

edited by

Sanja Stankovic

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4638 | Submission Open

Keywords: biomarker; cardiovascular disease; risk stratification; inflammation; vascular damage; micro-RNA; therapy; artificial intelligence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

p53—Oncogene, Tumor Suppressor Gene, Guardian of the Genome and the Cell

edited by Przemyslaw Bozko

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4621 | Submission Open

Keywords: p53; oncogene; tumor suppressor gene; tumor formation; anticancer therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Biology of Fish Stress

edited by

Tao Yin

Yong Long

and

Min Jin

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4598 | Submission Open

Keywords: fish stress; molecular biology; omics; apoptosis; inflammation

(This special issue belongs to the Section Molecular Biology)

Signal Transduction Mechanism in Plant Disease and Immunity: 2nd Edition

edited by

Hideo Nakashita

and

Takumi Nishiuchi

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4590 | Submission Open

Keywords: plant disease resistance; biotic stress; pathogen; plant-microbe interaction; priming; signal transduction; phytohormone; proteomics

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in Organic Chemistry: Molecule Synthesis and Reactions (2nd Edition)

edited by

José Justicia

and

Rachid Chahboun

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4496 | Submission Open

Keywords: bioactive natural products; organocatalysis; photoredox reactions; free-radical reactions; organometallic reactions; organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Role of Epigenetics in Genome Maintenance and Its Relationship to Organismal Aging and Age-Related Diseases

edited by Berta Vázquez and Gerardo Ferrer

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4494 | Submission Open

Keywords: chromatin; DNA damage; DNA repair; gene transcription; DNA replication; chromosome segregation; genome integrity; chromosome organization

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances in Secondary Metabolites in Plants

edited by

Sławomir Dresler

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4473 | Submission Open

Keywords: specialized metabolites; biosynthesis pathways; pharmacological applications; medicinal plants; plant stress resistance; abiotic and biotic elicitors; chemometric analysis; plant biotechnology; therapeutic potential; plant signaling and communication

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Understanding Molecular Mechanisms Involved in Chronic Kidney Injury and Repair

edited by

Milica Bozic

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4392 | Submission Open

Keywords: kidney disease; ischemic kidney injury; renal fibrosis; obesity; inflammation; oxidative stress; autophagy; senescence; cell death; small ncRNA

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neutrophil Extracellular Traps (NETs) in Immunity and Diseases, 3rd Edition

edited by

Jasmin Knopf

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4390 | Submission Open

Keywords: neutrophils; neutrophil functions; neutrophil extracellular traps (NETs); NET biology; NETs in autoimmune diseases; NETs in immune response; NETs in the development and progression of cancer diseases; NETs in immunothrombosis; degradation of NETs

(This special issue belongs to the Section Molecular Immunology)

Toxicity Mechanism of Emerging Pollutants: 2nd Edition

edited by

Monika Naumowicz

and

Joanna Kotyńska

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4370 | Submission Open

Keywords: emerging pollutant; toxicology; cancer; EDC; pesticides; microplastic; human cell lines; environment; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

New Advances in Cancer Genomics

edited by

Yoshihito Kano

submission deadline 20 Dec 2025 | 3 articles | Viewed by 4312 | Submission Open

Keywords: cancer genomics; biomarker discovery; precision oncology; KRAS and undruggable targets; artificial intelligence in oncology; multi-omics data integration; drug discovery

(This special issue belongs to the Section Molecular Biology)

Emerging Insights into Phytohormone Signaling in Plants

edited by Meng Zhang

submission deadline 20 Dec 2025 | 5 articles | Viewed by 4296 | Submission Open

Keywords: phytohormone; signal transduction; evolutionary and functional diversity; implications for plant science and agriculture

(This special issue belongs to the Section Molecular Plant Sciences)

Psoriasis: Molecular Research and Novel Therapy

edited by Tsen-Fang Tsai

submission deadline 20 Dec 2025 | 1 articles | Viewed by 4295 | Submission Open

Keywords: psoriasis; pathogenesis; treatment; biologics; novel therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pharmacological Treatment of Neuroinflammation

edited by Beatrice Polini

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4287 | Submission Open

Keywords: microglia; neuroinflammation; neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; therapeutic; natural molecules

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in 3D Tumor Models for Cancer Research

edited by

Simona Campora

Francesco Lopresti

and

Alessandra Lo Cicero

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4243 | Submission Open

Keywords: 3D systems; cancer research; spheroids; organoids; organ-on-chip; scaffolds; tissue engineering; biomedical technologies; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Latest Advances in Diabetes Research and Practice

edited by Ezekiel Uba Nwose

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4192 | Submission Open

Keywords: diabetes mellitus; cardiovascular risk; metabolic syndrome; antioxidants; oxidative stress; antiplatelet monitoring; evidence-based medicine; laboratory medicine

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Insights: Transitioning Fertility Research from the Laboratory to Clinical Practice

edited by Ekaterini Domali

submission deadline 20 Dec 2025 | 1 articles | Viewed by 4189 | Submission Open

Keywords: IVF/ICSI; male infertility; female infertility; fertility outcomes; endocrine disruptors; oxidative and reductive stress; molecular biology; biomarkers; proteomics; metabolomics; and transcriptomics; cell lines; early pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology and Treatment of Alzheimer's Disease

edited by

Jeffrey Fessel

submission deadline 20 Dec 2025 | 1 articles | Viewed by 4040 | Submission Open

Keywords: Alzheimer's disease; Alzheimer’ s dementia; neurodegeneration; AD; pathogenesis; cure for AD

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ovarian Cancer: Pathogenesis, Biomarkers and Treatment

edited by Alessandro Antonio Buda

submission deadline 20 Dec 2025 | 2 articles | Viewed by 4035 | Submission Open

Keywords: ovarian cancer; radiotherapy; diagnosis; prevention; treatment; fertility sparing

(This special issue belongs to the Section Molecular Oncology)

Arthritis: Focus on Pathologies, Symptoms and Therapy

edited by

Katarína Bauerová

submission deadline 20 Dec 2025 | 1 articles | Viewed by 4015 | Submission Open

Keywords: rheumatoid arthritis; autoimmune; pathogenesis; strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Rapeseed: Genetic Breeding, Key Trait Mining and Genome

edited by Hongbo Chao

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3986 | Submission Open

Keywords: rapeseed (Brassica napus L.); genetic breeding; genomic improvement; molecular markers; genome-wide association studies (GWAS); multi-omics integration; CRISPR gene editing; marker-assisted selection (MAS); stress resistance traits; yield and oil content improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Power Up Plant Genetic Research with Genomic Data: 3rd Edition

edited by

Hon-Ming Lam

Sachiko Isobe

and

Man-Wah Li

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3984 | Submission Open

Keywords: genome sequencing; optical mapping; genome editing; population genomics; genome-wide; association mapping; functional genomics; epigenomics; genetic interaction; chromatin; biodiversity

(This special issue belongs to the Section Molecular Genetics and Genomics)

Antiviral Strategies Targeting Capsid Proteins: Intervention from Assembly to Function

edited by

Yuqing Wu

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3894 | Submission Open

Keywords: viral capsid protein; assembly modulator/intervention; virus variants; antiviral therapeutics; assembly– disassembly

(This special issue belongs to the Section Macromolecules)

The Role of Mg Homeostasis in Disease: 2nd Edition

edited by

Juan Miguel Diaz-Tocados

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3844 | Submission Open

Keywords: magnesium; chronic diseases; diabetes; bone disease; mineral metabolism; renal disease; inflammation; cardiovascular disease

(This special issue belongs to the Section Biochemistry)

Novel Trends in the Research of Molecules Involved in Skin Inflammation and Dermatologic Conditions

edited by

Liborija Lugovic-Mihic

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3826 | Submission Open

Keywords: atopic dermatitis; contact dermatitis; psoriasis; urticaria; eczema; acne; rosacea; seborrheic dermatitis; drug-induced reaction; prurigo nodularis; lichen; hidradenitis suppurativa; alopecia; chronic urticaria; skin tumor; angioedema; venous ulcer; HPV skin manifestations; skin infection; vitiligo

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Veterinary Science

edited by

JeongWoo Kang

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3774 | Submission Open

Keywords: forensic pathology and necropsy; forensic toxicology; DNA analysis in veterinary forensics; the role of veterinarians in legal investigations; case studies in veterinary forensics

(This special issue belongs to the Section Molecular Toxicology)

Advances in Vegetable Breeding and Molecular Research

edited by

Ai-Sheng Xiong

and

Mengyao Li

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3614 | Submission Open

Keywords: vegetable breeding; gene editing; omics; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Research on Nutrition and Epigenetics in Cancer

edited by

Marisabel Mecca

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3463 | Submission Open

Keywords: diet; nutrition; epigenetics; cancer; cancer therapy; lifestyle

(This special issue belongs to the Section Molecular Oncology)

Design of Bioactive Agents and Interaction with Biological Systems

edited by

Josef Jampilek

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3453 | Submission Open

Keywords: natural and synthetic compounds; bioactive agents and materials; design and discovery; targeting; intermolecular interactions; omics; structure and dynamics of biomolecules; theoretical analysis of biomolecular structures; analytical and biophysical methods; molecular biology/biochemistry; chemical biology/biological chemistry

(This special issue belongs to the Section Molecular Biology)

The Use of Molecular Biology in the Targeted Prevention, Diagnosis and Therapy of Microbial Infections

edited by

Maria D'Accolti

and

Elisabetta Caselli

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3273 | Submission Open

Keywords: microbial infections; AMR; molecular biology; One Health; microbiome

(This special issue belongs to the Section Molecular Microbiology)

New Insights of Autophagy and Apoptosis in Cells

edited by

Mirko Pesce

and

Antonia Patruno

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3267 | Submission Open

Keywords: autophagy; apoptosis; signal transduction; cell survival

(This special issue belongs to the Section Molecular Biology)

Oxidative Stress and Inflammation in the Tissue Repair—Pathways and Biotechnologies

edited by Reggiani Vilela Gonçalves and Rômulo Dias Novaes

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3253 | Submission Open

Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; remodeling; molecular pathways; apoptotic alterations; diabetes; tissue repair

(This special issue belongs to the Section Biochemistry)

Properties and Applications of Nanoparticles and Nanomaterials: 3rd Edition

edited by Xiaogang Li

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3189 | Submission Open

Keywords: nanostructures; nanoparticles; microstructure characterization; material design; evaluation of mechanical properties; applications of nanomaterials

(This special issue belongs to the Section Molecular Nanoscience)

Histopathological and Cytological Biomarkers for Breast and Gynecologic Cancers

edited by Ilias P. Nikas,

Ioannis Pateras

and

Yosep Chong

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3143 | Submission Open

Keywords: pathology; cytopathology; malignant effusions; biomarker; breast cancer; ovarian cancer; endometrial cancer; cervical cancer; metastasis; immunohistochemistry; immunocytochemistry; immunotherapy; genomics; proteomics; personalized medicine; prognosis and therapy; digital pathology; artificial intelligence; machine learning

(This special issue belongs to the Section Molecular Oncology)

New Insight into Radiation Biology and Radiation Exposure

edited by Lynnette Cary

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3133 | Submission Open

Keywords: ionizing radiation; radiation biomarkers; radionuclide; medical countermeasure

(This special issue belongs to the Section Molecular Biology)

Innovative Approaches in Organic Synthesis and Functional Materials: From Design to Biological Impact

edited by

Antonio Rescifina

and

Chiara Zagni

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3115 | Submission Open

Keywords: organic synthesis; bioactive molecules; functional materials; molecular informatics; biological activity; molecular docking; computational chemistry; drug design; medicinal chemistry; quantitative structure– activity relationships (QSARs); environmental applications; sustainable chemistry; natural products

(This special issue belongs to the Section Molecular Informatics)

The Role of Metabolism-Related Pathways in Animal Growth, Development, Disease and Behavior

edited by

Runxiang Zhang

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3098 | Submission Open

Keywords: metabolism pathway; signal pathway; animal development; animal behavior; animal disease

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Extraction, Isolation and Identification of Natural Chemicals

edited by Jiaozhen Zhang

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3090 | Submission Open

Keywords: extraction; isolation; identification; natural chemicals; biological activities

(This special issue belongs to the Section Biochemistry)

Drug Delivery Systems in Veterinary Medicine: Innovations and Applications

edited by

Hualin Fu

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3008 | Submission Open

Keywords: design of novel veterinary drug delivery systems; methods of preparing a veterinary drug delivery system; mechanisms of action of veterinary drug delivery systems; impact of veterinary drug delivery systems on in vivo processes of veterinary drugs; clinical evaluation of veterinary drug delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

Cardioprotection and Mitochondrial Signaling: Insights from Molecular Mechanisms to Therapeutic Strategies

edited by Cecilia Zazueta

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3006 | Submission Open

Keywords: cardioprotection; mitochondrial signaling; mitochondrial dysfunction; heart failure; ischemia/reperfusion; mitochondria; reactive oxygen species

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Diseases in Humans and Animals: From Emergence to Translational Medicine

edited by

Pawel Kordowitzki

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2995 | Submission Open

Keywords: animal diseases; human diseases; viruses; bacteria; translational medicine; environment; zoonosis; One Health; disease models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Development and Validation of New Analytical Methods for the Determination of Drugs and Their Metabolites

edited by

Anna Petruczynik

submission deadline 20 Dec 2025 | 2 articles | Viewed by 2951 | Submission Open

Keywords: drugs; drug formulations; pharmacokinetics; metabolism studies; analytical techniques

(This special issue belongs to the Section Molecular Pharmacology)

Future Perspectives and Challenges in Molecular Research of Glioma

edited by Shanchun Guo

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2923 | Submission Open

Keywords: gliomas; genetic and epigenetic changes; molecular mechanisms; immunotherapy; innovative therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Viral Diseases of the Respiratory System—Molecular Mechanisms and Pathogenesis: 3rd Edition

edited by

Andreas Beineke

submission deadline 20 Dec 2025 | 4 articles | Viewed by 2904 | Submission Open

Keywords: respiratory diseases; pneumonia; pneumotropic viruses; pathogenesis; host– pathogen interaction; pulmonary pathology; immunopathology; immunity; disease prevention; treatment; zoonotic diseases; antiviral therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 301-350 on page 7 of 66.

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