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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microbes in Obstetrics: Current Importance of Ascending Bacterial Infection (ABI)

edited by Alfredo Ovalle and Enrique Oyarzun

submission deadline 28 Feb 2027 | Viewed by 331 | Submission Open

Keywords: ascending bacterial infection (ABI); vaginal dysbiosis; spontaneous preterm birth (sPTB); group B streptococcus (GBS); fetal inflammatory response syndrome (FIRS); microbiomics; maternal immunology; cervical insufficiency

(This special issue belongs to the Section Molecular Microbiology)

Advances in Neuropharmacology: From Molecular Design to Preclinical Models

edited by

Jana Tchekalarova

and Miroslav A. Rangelov

submission deadline 28 Feb 2027 | Viewed by 330 | Submission Open

Keywords: neuropharmacology; drug discovery; molecular modeling; preclinical models

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Genetics of Arthritis

edited by

Bouchra Edderkaoui

submission deadline 28 Feb 2027 | Viewed by 328 | Submission Open

Keywords: arthritis; genetic susceptibility; genome-wide association studies; population genetics; genetic loci; epigenetics; gene-environmental interaction; polygenic risk scores; transcriptomics; single-cell sequencing; genomics; rare variants; polymorphisms; candidate genes; autoimmunity genetics; genetics of cartilage; degeneration, regeneration, and inflammatory pathways; genetic biomarkers; pharmacogenomics; functional genomics; precision medicine/ personalized treatments

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research in Postharvest Biology

edited by Hua Zhang

submission deadline 28 Feb 2027 | Viewed by 326 | Submission Open

Keywords: postharvest biology; molecular regulation; plant hormone signaling; gas signaling molecules; ripening-related genes; transgenic technology; postharvest quality preservation

(This special issue belongs to the Section Molecular Plant Sciences)

Vitamin D in Reproductive Disorders: Determinants, Metabolism, and Downstream Biological Mechanisms

edited by

Eugenia Mata-Greenwood

submission deadline 28 Feb 2027 | Viewed by 319 | Submission Open

Keywords: vitamin D; perinatal corticosteroids; placental insufficiency; intrauterine growth restriction; cortisol metabolism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Coordination Architectures for Next-Generation Chemical Sensors: Metal Complexes, Coordination Polymers and MOFs

edited by

Tamara Basova

and

Darya Klyamer

submission deadline 28 Feb 2027 | Viewed by 315 | Submission Open

Keywords: metal complexes; coordination polymers; MOFs

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Advances in Biomarkers of Central Nervous System Diseases and Disorders: 2nd Edition

edited by

David Gurwitz

and

Chiara Villa

submission deadline 28 Feb 2027 | 2 articles | Viewed by 313 | Submission Open

Keywords: RNA biomarkers; CNS disorders; autism spectrum disorder; precision medicine

(This special issue belongs to the Section Molecular Neurobiology)

Exploring Molecular Mechanisms of Lens Development and Growth

edited by

Michael L. Robinson

submission deadline 28 Feb 2027 | Viewed by 312 | Submission Open

Keywords: lens development; lens fiber cell differentiation; organelle degradation; transcriptional regulation; signal transduction; lens regeneration; chromatin remodeling; ocular development

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Treatments of Prostate Cancer

edited by

Sara Merler

submission deadline 28 Feb 2027 | Viewed by 309 | Submission Open

Keywords: prostate cancer; molecular mechanisms; tumor progression; androgen receptor signaling; genetic and epigenetic alterations; biomarkers; tumor microenvironment; therapeutic resistance; targeted therapies

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Biomarkers of Renal Injury: Bridging the Gap Between Micro-Environment Damage and Clinical Diagnosis

edited by Alexandre Braga Libório

submission deadline 28 Feb 2027 | Viewed by 305 | Submission Open

Keywords: renal injury; molecular biomarkers; AKI-CKD transition; regulated cell death; precision nephrology; renal microenvironment; epigenetics; tubulointerstitial fibrosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Effects of Diets and Environmental Pollutants on the Intestine and Liver: A Molecular Perspective

edited by

Aneta Sokal-Dembowska

submission deadline 28 Feb 2027 | Viewed by 304 | Submission Open

Keywords: gut–liver axis; diet; environmental pollutants; molecular mechanisms; gut microbiota; intestinal barrier; liver disease; inflammation; oxidative stress; epigenetics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Extracellular Vesicles as Drivers of Cancer Therapy Resistance: Mechanistic Insights and Emerging Therapeutic Strategies

edited by Abraham Pedroza-Torres

submission deadline 28 Feb 2027 | Viewed by 299 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer resistance; tumor microenvironment; biomolecule transfer

(This special issue belongs to the Section Molecular Oncology)

Molecular Progression of Gut Microbiota—2nd Edition

edited by

Emina Pustijanac

submission deadline 28 Feb 2027 | Viewed by 298 | Submission Open

Keywords: gut microbiota; microbiome; differences in gut microflora; molecular techniques; gut microbiota’s role and composition; healthy state; dysbiosis

(This special issue belongs to the Section Molecular Microbiology)

Backend Databases in Pharmacogenomics and Genome Informatics

edited by Alireza Tafazoli

submission deadline 28 Feb 2027 | Viewed by 293 | Submission Open

Keywords: pharmacogenomics; genome informatics; genomic databases; variant interpretation; pharmacogene nomenclature; genotype-to-phenotype translation; clinical decision support; application programming interfaces; FAIR genomic data

(This special issue belongs to the Section Molecular Informatics)

Current Issues in Natural Product Bioactivity and Drug Discovery

edited by

Bey-Hing Goh

Jun-Ho Kim

and Pei Lou Wong

submission deadline 28 Feb 2027 | Viewed by 291 | Submission Open

Keywords: natural products; drug discovery; bioprospecting; pharmacology; multi-omics; molecular biology; bioactivity; advanced screening; emerging technologies; artificial intelligence

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Biomedical and Tissue Engineering Strategies to Cross the Blood–Brain Barrier for Next-Generation Treatments Against Neurodegenerative Diseases, 2nd Edition

edited by Livia La Barbera

submission deadline 28 Feb 2027 | Viewed by 291 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer’s disease; CNS; blood–brain barrier; drug delivery systems; nanocarriers; nanomedicine; tissue engineering; theranostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Obesity and Its Associated Diseases: Molecular and Metabolic Pathways

edited by Verónica J. Miksztowicz

submission deadline 28 Feb 2027 | Viewed by 286 | Submission Open

Keywords: obesity; dietary patterns; metabolic pathways; adipose tissue dysfunction; chronic low-grade inflammation; insulin resistance; mitochondrial dysfunction; oxidative stress; adipokine signaling; inter-organ crosstalk

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Protein Inhibition and Metabolism

edited by Song Wang

submission deadline 28 Feb 2027 | Viewed by 285 | Submission Open

Keywords: protein inhibition; metabolism; computational chemistry; molecular modeling; therapeutic targets

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Cytokine Signaling in the Bone Marrow Niche: Implications for Hematopoiesis in Health and Disease

edited by

Melinda Varney

submission deadline 28 Feb 2027 | Viewed by 280 | Submission Open

Keywords: bone marrow niche; bone marrow cytokine signaling; hematopoiesis; hematopoietic stem cells; microenvironmental regulation; inflammatory signaling; hematologic disease

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Cancer Immunotherapy Research

edited by

Luigi Pasini

submission deadline 28 Feb 2027 | Viewed by 280 | Submission Open

Keywords: immunotherapy; CAR T-Cell therapy; mRNA cancer vaccines; ICIs; TIL therapy; nanotechnology; antibody discovery; drug discovery; tumor microenvironment; microbiome modulation; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

Non-Mammalian Models in Toxicology Research on Environmental Pollutants

edited by

Ida Ferrandino

and

Giovanni Scillitani

submission deadline 28 Feb 2027 | Viewed by 278 | Submission Open

Keywords: environment; pollution; pollutants; contaminants; non-mammalian models; animals; toxicology; invertebrates; lower vertebrates

(This special issue belongs to the Section Molecular Toxicology)

Innovative Advances in Cancer Therapy Through Nano-Based Systems

edited by

Lenuţa-Maria Şuta

and

Claudia Geanina Watz

submission deadline 28 Feb 2027 | Viewed by 274 | Submission Open

Keywords: nano-enabled delivery systems; innovative nanomaterials; smart nanocarriers; cancer nanotherapy; anti-tumorigenic activity

(This special issue belongs to the Section Molecular Nanoscience)

Computational Strategies for Antiviral Drug Discovery: QSAR, In Silico Modeling and Data-Driven Approaches

edited by

Mohammed Salah

submission deadline 28 Feb 2027 | Viewed by 272 | Submission Open

Keywords: antiviral drug discovery; viral diseases; computational drug design; in silico modeling; quantitative structure–activity relationship (QSAR); molecular modeling; molecular dynamics simulations; virtual screening; machine learning in drug discovery; bioactive compounds; computer-aided drug design (CADD)

(This special issue belongs to the Section Molecular Informatics)

Molecular Toxicity and Therapeutic Potential of Hymenoptera Venoms

edited by

Xesús Feás

submission deadline 28 Feb 2027 | Viewed by 271 | Submission Open

Keywords: hymenoptera venom; molecular toxicology; allergenicity; venom peptides; therapeutic applications; drug discovery; envenomation; bioactive compounds

(This special issue belongs to the Section Molecular Toxicology)

Cancer Genomics: Key Advances in the Precision Era

edited by

Maria Samara

submission deadline 28 Feb 2027 | Viewed by 269 | Submission Open

Keywords: cancer genomics; next-generation sequencing; artificial intelligence; computational biology; liquid biopsy; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Oral Cancer

edited by Junichi Tanuma

submission deadline 28 Feb 2027 | Viewed by 264 | Submission Open

Keywords: oral squamous cell carcinoma; tumor microenvironment; immune regulation; molecular signaling; metabolic reprogramming; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Emerging Advances in Fluorescent Biosensors

edited by

Xiaolong Liu

submission deadline 28 Feb 2027 | Viewed by 263 | Submission Open

Keywords: single molecule imaging; fluorescent probes; super-resolution imaging

(This special issue belongs to the Section Molecular Biophysics)

Pharmacological Mechanisms of Natural Products: Biological Targets and Clinical Perspectives

edited by Damião Pergentino De Sousa

submission deadline 28 Feb 2027 | Viewed by 262 | Submission Open

Keywords: central nervous system; inflammation; cancer; infection; metabolism; essential oils; medicinal plants; alkaloids; flavonoids; natural products

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Nutrition and Functional Foods: Mechanisms of Metabolic Health Regulation

edited by

Eugene Chang

submission deadline 28 Feb 2027 | Viewed by 262 | Submission Open

Keywords: nutrients; bioactive food components; functional food; signaling pathways; metabolism; metabolic regulation; nutrigenomics; gut microbiota; inflammation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bringing New Molecular Insights into Neurodegenerative Diseases

edited by

Daniela Vecchio

submission deadline 28 Feb 2027 | Viewed by 261 | Submission Open

Keywords: neurodegeneration; pathogenic mechanisms; biomarkers; neuroimaging; artificial intelligence; protein aggregation; neuroinflammation; genetics and epigenetics; multi-omics; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Regulation of Cancer Stem Cells: Signaling Networks, Metabolism, and Therapeutic Targeting

edited by Shanchun Guo

submission deadline 28 Feb 2027 | Viewed by 260 | Submission Open

Keywords: glioma; cancer stem cell; drug design; small molecular; diagnosis; prognosis; pathology

(This special issue belongs to the Section Molecular Oncology)

Epigenetic Mechanism in Gynecologic Oncology

edited by

Aneta Słabuszewska-Jóźwiak

submission deadline 28 Feb 2027 | Viewed by 249 | Submission Open

Keywords: epigenetics; cancer; molecular medicine; molecular mechanism; gene expression; cancer pathogenesis

(This special issue belongs to the Section Molecular Oncology)

Latest Research in Biomarkers of Neurodegenerative Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 28 Feb 2027 | Viewed by 236 | Submission Open

Keywords: biomarkers; neurodegenerative diseases; amyloid; oxidative stress; neuroinflammation; aging

(This special issue belongs to the Section Molecular Neurobiology)

Pharmacology of Neuropathic and Inflammatory Pain

edited by

N. L. Caram-Salas

and Hector Isaac Rocha-González

submission deadline 28 Feb 2027 | Viewed by 233 | Submission Open

Keywords: neuropathic pain; inflammatory pain; diabetic neuropathy; neuropharmacology; neuroinflammation; ion channels; sexual dimorphism; precision pain medicine; pharmacogenomics; proteomics, transcriptomics, and metabolomics in analgesic discovery

(This special issue belongs to the Section Molecular Pharmacology)

Photoreceptors and the Optic Nerve

edited by Ruth Estela Rosenstein and Damian Dorfman

submission deadline 28 Feb 2027 | Viewed by 233 | Submission Open

Keywords: photoreceptors; optic nerve; neurodegeneration; neuroprotection; experimental models; retina

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Biopolymers: From Natural Origins to Biomedical Hydrogels and Drug Delivery Systems

edited by Abril Fonseca García

submission deadline 28 Feb 2027 | Viewed by 229 | Submission Open

Keywords: polysaccharides; biomaterials; hydrogels; biomedicine; food packaging; water treatment

(This special issue belongs to the Section Macromolecules)

Advances in Allergen Prediction, Characterization, and Immunoinformatics

edited by

Katarina Smiljanić

submission deadline 28 Feb 2027 | Viewed by 227 | Submission Open

Keywords: allergen prediction; allergen characterization; proteomics; immunoinformatics; environmental allergens; food allergens; IgE epitopes; molecular docking; machine learning; mass spectrometry

(This special issue belongs to the Section Molecular Immunology)

Molecular Research in Cerebral Ischemia: From Microglial States to Angiogenic Resilience

edited by Abdullah Ahmad

submission deadline 28 Feb 2027 | Viewed by 223 | Submission Open

Keywords: cerebral ischemia; neurovascular unit; microglial plasticity; angiogenic resilience; microvascular regeneration; innate immune activation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Composites of Cellulose and Cellulose Derivatives: Engineering and Applications

edited by

Omar A. El Seoud

submission deadline 28 Feb 2027 | Viewed by 209 | Submission Open

Keywords: cellulose composites: engineering and applications; composites of cellulose esters: engineering and applications; composites of cellulose ethers: engineering and applications; molecular interactions within cellulose and its derivatives; molecular interactions within composites of cellulose and its derivatives

(This special issue belongs to the Section Macromolecules)

Extracellular Vesicles in Physiological Regulation: From Intercellular Communication to Tissue Homeostasis

edited by

Denis Silachev

submission deadline 28 Feb 2027 | Viewed by 202 | Submission Open

Keywords: extracellular vesicles; intercellular communication; tissue homeostasis; physiological regulation; organ crosstalk; immune homeostasis; metabolic adaptation; neuroglial communication; stem cell niches; extracellular RNA

(This special issue belongs to the Section Molecular Biology)

Crop Stress Tolerance: From Mechanisms to Breeding

edited by Awais Farooq and

Umer Karamat

submission deadline 28 Feb 2027 | Viewed by 196 | Submission Open

Keywords: root phenomics; plant–microbiome interactions; rhizosphere biology; crop genetics; genome-wide association mapping; computational biology; functional genomics and gene editing; abiotic stress adaptation; biological nitrification inhibition; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

New Insights into Retinal Degenerative Diseases

edited by

Deokho Lee

submission deadline 28 Feb 2027 | Viewed by 195 | Submission Open

Keywords: age-related macular degeneration; ischemic retinopathy; glaucoma; diabetic retinopathy; polyphenols; mitochondria; choroidal neovascularization; vitamins; oxidative stress; cell therapy; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Xenobiotic Toxicity and Biological Detoxification

edited by

José Belisario Leyva-Morales

submission deadline 28 Feb 2027 | Viewed by 187 | Submission Open

Keywords: molecular toxicology; xenobiotics; toxicogenomics; biomarkers; oxidative stress; mitochondrial dysfunction; adverse outcome pathways; biodegradation; biological detoxification; environmental health

(This special issue belongs to the Section Molecular Toxicology)

Impact of Signaling and Function of Individual Incretin Receptors on the Pharmacology of Incretin-Based Drugs

edited by

Anastasios Lymperopoulos

submission deadline 28 Feb 2027 | Viewed by 186 | Submission Open

Keywords: drug development; incretin; signal transduction; obesity; metabolism; G protein-coupled receptor; receptor pharmacology; translational medicine

(This special issue belongs to the Section Molecular Pharmacology)

Regenerative Medicine: Stem Cells, Extracellular Vesicles, Bioinspired Nanovesicles, and Artificial Intelligence for Precision Tissue Repair

edited by

Prakash Gangadaran

and

Ramya Lakshmi Rajendran

submission deadline 28 Feb 2027 | Viewed by 182 | Submission Open

Keywords: stem cells; extracellular vesicles; nanovesicles; exosome; artificial intelligence; regenerative medicine; tissue repair

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Advances in Cardiac Injury and Repair

edited by Rajika Roy

submission deadline 28 Feb 2027 | Viewed by 182 | Submission Open

Keywords: MI; TAC; cardiomyocytes; injury; stem cells; iPSC; biomaterials; mitochondria; receptors; GRKs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Discovery, Synthesis, and Design of Novel Antibacterial Agents

edited by Md. Amdadul Huq

submission deadline 28 Feb 2027 | Viewed by 180 | Submission Open

Keywords: antibacterial agents; antimicrobial resistance; molecular drug discovery; biological synthesis; chemical synthesis; biofilm inhibitors; molecular mechanisms of action; antibacterial therapeutics

(This special issue belongs to the Section Biochemistry)

Advanced Research in Nanomaterials in Drug Delivery

edited by Abul Kalam Azad

submission deadline 28 Feb 2027 | Viewed by 179 | Submission Open

Keywords: nanomaterials; drug delivery; nanomedicine; targeted drug delivery; polymeric nanoparticles; lipid nanoparticles; controlled drug release; biomaterials; gene delivery; translational nanomedicine

(This special issue belongs to the Section Molecular Nanoscience)

Islet Transplantation: Molecular Mechanisms and Translational Approaches

edited by Wanxing Cui

submission deadline 28 Feb 2027 | Viewed by 175 | Submission Open

Keywords: islet transplantation; stem cell-derived islets; islet isolation and preservation; biomaterial encapsulation; xenotransplantation; iPSC-derived beta cells; islet oxygenation and revascularization; cGMP cell manufacturing; islet autotransplantation; beta-cell replacement therapy; islet engraftment; immune tolerance; autoimmune disease recurrence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Nanocomposite Materials for Photocatalytic and Antimicrobial Applications

edited by

Vesna Lazić

submission deadline 28 Feb 2027 | Viewed by 171 | Submission Open

Keywords: nanocomposites; photocatalysis; antimicrobial materials; hybrid nanomaterials; semiconductor nanomaterials; green synthesis; reactive oxygen species; photocatalytic hydrogen production; environmental remediation; water treatment; air purification; antibiofilm activity; surface functionalization; structure–property relationships; advanced functional materials

(This special issue belongs to the Section Molecular Nanoscience)

Displaying special issue 2501-2550 on page 51 of 63.

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