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Special Issue "Plant Proteomic Research 4.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Prof. Dr. Sixue Chen
Guest Editor
Department of Biology, Genetics Institute, Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, FL 32610, USA
Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL 32610, USA
Interests: signaling and metabolic mechanisms underlying plant interaction with the environment

Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our 2016 Special Issue, "Plant Proteomic Research" (https://www.mdpi.com/journal/ijms/special_issues/plant-proteomic), “Plant Proteomic Research 2.0” (https://www.mdpi.com/journal/ijms/special_issues/plant-proteomic_2) and “Plant Proteomic Research 3.0” (https://www.mdpi.com/journal/ijms/special_issues/plant-proteomic_3).

Advancement in high-throughput “Omics” techniques has revolutionized plant molecular biology research. Proteomics offers one of the best approach for the functional analysis of the genome, generating detailed information that can be integrated with those obtained by other classic and -omics approaches. It thus provides a deep knowledge and understanding of the diverse proteoforms and different plant processes. Several different generations of proteomics platforms (e.g., gel-based, gel free, isotope-labeling, label free, data-dependent and data-independent) have appeared in the past twenty years. They have been exploited in describing protein profiles, posttranslational modifications, protein turnover, protein complex and interactions, subcellular proteomes, single cell and single-cell type proteomes. Nevertheless, the ultimate success of any proteomic strategy lies in the various factors, including isolation of full component of proteins, separation, visualization and their accurate characterization. Despite recent advancements, more emphasis needs to be given to the protein sample preparation protocols, especially for very low-abundant, hydrophobic, and large molecular weight. Thus, the amalgamation of diverse MS techniques, complemented with genome-sequence data and modern bioinformatics analysis with improved sample preparation and fractionation strategies, offer a powerful tool to identify and characterize novel proteins/proteoforms in spatial and temporal resolution and under different environmental conditions. Furthermore, post-translational modifications and protein–protein interactions provide deep insight into protein molecular function. Authors are welcome to submit original research articles and reviews addressing recent advancements, as well as limitations of current proteomic techniques and their diverse applications to gain new insights into plant molecular responses to various biotic and abiotic stressors and the molecular bases of other processes. Proteomics focus is also related to translational purposes, including food traceability and allergen detection. In addition, bioinformatic techniques are needed for more confident identification, quantitation, data analysis, networking and multi-omics, especially with non-model, orphan, plants, including medicinal, meditational plants and forest tree species.

Prof. Dr. Sixue Chen
Prof. Dr. Setsuko Komatsu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • plant proteomic research
  • methods, techniques and protocols of plant proteomics
  • applications of plant proteomics

Published Papers

This special issue is now open for submission.
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