Special Issue "Glioma Cell Invasion"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 September 2017).
Interests: brain cancer (paediatric and adult); tumour cell invasion; blood brain barrier; subventricular zone; neuropathology
Tumour cell invasion is a key hallmark in primary malignant brain cancer in both adults and children and remains one of the most critical factors involved in therapeutic resistance and recurrence. Lacking somewhat in the literature is how components of the tumour microenvironment (which change during tumour growth and in response to therapy) work together to support tumour growth, resistance, adaptation and recurrence. The aim of this Special Issue is to bring together specific areas and provide a broad overview on the topic of “Microenvironmental Influences on Glioma Cell Invasion” in the context of cell to cell bidirectional and unidirectional communication, molecular/signalling drivers, immunologic perspectives, metabolic influences, physical/mechanical perspectives, flow dynamics (vascular and CSF), radiation and therapeutic effects, mathematical models, and future perspectives on translational considerations. In addition, the types or modes of tumour dissemination will also be a topic. This Special Issue will provide an overview on the spatial and temporal dynamic impact on glioma cell invasion.
Prof. Geoffrey J. Pilkington
Prof. Helen L. Fillmore
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Glioma invasion
- CSF flow dynamics
- Metabolism and cell migration
- CNS interstitial space
- Cellular organelle changes during invasion
- Immune system
- Modelling cell migration/invasion
- Subventricular Zone
- White matter tracts
- Cell cycle