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Special Issue "Molecular Mechanism of Infectious Disease"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 December 2017).
Interests: infectious diseases; tuberculosis; retrovirus; dengue; osteopontin; galectin-9
Special Issues and Collections in MDPI journals
The acute infection of pathogens elicits strong immune responses in the host to clear invading pathogens and infected cells. These innate and adaptive immune responses lead to the eventual recovery of most infected individuals. Numerous proteins from pathogens, signal molecules, receptors, cytokines, and chemokines have been known to be involved in this process. Each pathogen has unique ways to infect, and has employed mechanisms to escape and/or evade the host immune responses. In some cases, acute symptoms develop into fatal systemic deterioration showing coagulation abnormality or immunological tolerance. Systemic reactions can lead to poor understanding of underlying biological events during the acute phase of immune response. Emerging knowledge of new inflammatory molecules revealed a novel aspect of the pathophysiology of acute infectious diseases. For example, matricellular proteins (MCPs) that are usually present in the extracellular space were found to be elevated in patients with acute infection. However, their exact roles in this context are poorly understood because MCPs have diverse functions including interactions with cell surface receptors, such as integrins, growth factors, and protease. In this Special Issue, we will focus on the novel molecules involved in infection to have a better understanding of infectious diseases.
Prof. Dr. Toshio Hattori
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Matrix protein