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Viral Infections and Host Antiviral Responses: Molecular Mechanisms and Molecular Regulation

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 25

Special Issue Editor


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Guest Editor
Institute of Animal Sciences (IAS), Chinese Academy of Agricultural Sciences (CAAS), Beijing, China
Interests: African swine fever virus; ASFV vaccine; live vector vaccine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Viruses exploit sophisticated molecular strategies to invade host cells, replicate, and evade immune defenses, while hosts deploy intricate regulatory mechanisms—from innate immune sensors to epigenetic and post-transcriptional controls to limit infection. Understanding these dynamic molecular interactions is critical for developing effective antiviral therapies and vaccines.

This Special Issue, “Viral Infections and Host Antiviral Responses: Molecular Mechanisms and Molecular Regulation,” welcomes original research and reviews that elucidate the molecular underpinnings of viral infection and host antiviral responses. Topics of interest include viral entry and replication mechanisms, host restriction factors, interferon signaling, immune evasion tactics, the roles of non-coding RNAs and post-translational modifications, and emerging molecular targets for intervention. By integrating mechanistic insights across human and animal virology, this collection aims to advance fundamental knowledge and foster innovation in antiviral strategies.

Dr. Hong Jia
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antiviral immunity
  • viral entry
  • host–virus interaction
  • innate immunity
  • interferon signaling
  • viral immune evasion
  • non-coding RNAs
  • post-translational modifications
  • molecular therapeutics
  • viral pathogenesis

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Published Papers

This special issue is now open for submission.
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