Special Issue "Skin Inflammation Aging and Diseases"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 28 February 2021.
Interests: photodermatology; inflammatory skin diseases
The skin is the most precious dress we wear every day.
It is the body's largest organ, with a complex structure made of several tissue layers, each with a distinct cellular composition. Its most important function is to form a “barrier” to protect our body from environmental insults. The skin is a high-turnover organ, with a continuously regenerating epidermis. With aging, both the epidermis and the dermis lose their regenerative ability, undergoing thinning, wrinkling, dryness, and mottling (intrinsic aging).
The inability to restore the integrity of the skin barrier can result in many cutaneous health problems such as inflammatory skin conditions.
In turn, chronic inflammation may enhance and speed aging.
Chronic exposure to environmental elements like ultraviolet (UV) radiations cause deleterious effects in skin cells; in fact, UVA and UVB radiation are associated with skin photo-aging, various inflammatory disorders, and also skin cancer (extrinsic aging). Research in recent years has advanced our understanding of the pathophysiology of inflammatory skin diseases and skin cancer, as well as of therapeutic options for skin aging.
Nevertheless, many aspects remain to be explored: what is the role of the skin microenvironment in aging, inflammation, and cancer? Is there a link between skin aging, chronic inflammation, and skin cancer? Do they share molecular inflammatory pathways? Can we identify predictive biomarkers?
This Special Issue calls for original research papers, full reviews, and perspectives that address our current knowledge and progress in the field of skin inflammation, aging, and disease, to find possible answers to the mentioned questions and to others related to the keywords reported below.
Dr. Serena Lembo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Skin health
- Skin barrier
- Inflammation Aging
- Photoaging Intrinsic aging
- Extrinsic aging
- Skin cancer
- Inflammatory skin conditions
- Oxidative stress
- Molecular inflammatory pathways