Serotonin in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (15 January 2020) | Viewed by 147783
Special Issue Editors
Interests: monoamines; neurochemistry; addiction; Parkinson's disease; schizophrenia; neuropharmacology; mood disorders
Special Issues, Collections and Topics in MDPI journals
2. Neuroscience Division, School of Biosciences, Cardiff University, Cardiff CF10 3AX, UK
Interests: serotonin; GABA; dopamine; epilepsy; addiction; mood disorders; electrophysiology; habenula; basal ganglia; serotonin2 receptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Serotonin is a neurotransmitter acting in the central nervous system and neurohormone controlling the function of peripheral organs. Despite the distinct organization of the serotonergic system in lower animals compared to vertebrates, its function which impacts virtually all biological processes is quite well conserved across the animal kingdom. Serotonin acts on a variety of serotonin receptors conferring some specificity of the serotonergic transmission in biological processes due to the distinct distribution and/or coupling efficiency of each serotonergic receptor. Beyond its widespread implication in physiology, the serotonergic system is involved in numerous diseases of the central nervous system (e.g., depression, anxiety, schizophrenia, obsessive-compulsive disorders, addiction, Parkinson’s disease) and peripheral organs (e.g., gastrointestinal disorders, cardiac arrhythmia, hypertension). Numerous drugs targeting the serotonergic system are currently used in the clinic for different purposes. The recent progress made on the function and dysfunction of the serotonergic system will certainly increase their number.
The purpose of this Special Issue is to review the current state of knowledge of serotonergic mechanisms in health and diseases which will consider both original research articles and reviews. Contributions from different fields of research are welcomed.
Prof. Philippe De Deurwaerdère
Prof. Giuseppe Di Giovanni
Guest Editors
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Keywords
- Physiology
- pathophysiology
- serotonin receptor
- pharmacology
- molecular pathway
- behaviour
- peripheral organs
- system interaction
- genomic
- animal kingdom
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