New Molecular Targets in Systemic Lupus Erythematosus and Lupus Nephritis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 5001
Special Issue Editors
Interests: systemic lupus erythematosus; antiphospholipid syndrome; systemic sclerosis; rheumatoid arthritis; biomarkers; T lymphocytes; autoantibodies; adaptive immunity; bDMARDs
Interests: systemic lupus erythematosus; lupus nephritis; sarcoidosis; systemic sclerosis; interstitial lung disease; myositis; vasculitis; emergency medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Systemic lupus erythematosus (SLE), a prototypic autoimmune disease, has seen significant advances over the recent years in terms of molecular pathways involved and a clearer understanding of the pathophysiology. In addition, new molecular targets are being developed and tested, resulting in exciting times for patients and physicians. Nevertheless, many of the developed drugs fail to demonstrate a benefit in subsequent clinical trials. The kidneys are the major organs affected by systemic autoimmune diseases, and lupus nephritis (LN) is one of the most feared complications of SLE, which considerably increasing morbidity and mortality. However, new therapeutic options have emerged with the recent approval of anifrolumab, an anti-interferon antibody, and voclosporine, a novel calcineurin inhibitor. These opportunities come with the challenge of finding their place in the therapeutic algorithms but represent a step forward toward tailoring treatment to individual patients.
This Special Issue aims to provide a forum for new research findings and reviews on the molecular pathways involved in the pathophysiology of SLE and LN, deepening our understanding of this heterogeneous and challenging disease.
We invite basic, translational and clinical scientists from all specialties involved in the research and care of SLE patients to contribute their findings to our themed issue.
Dr. Silvia Piantoni
Dr. Peter Korsten
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- systemic lupus erythematosus
- lupus nephritis
- targeted therapies
- adaptive immunity
- autoantibodies
- biomarkers
- pathophysiology
- translational research
- clinical research.
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.