New Sight of Biomarkers in Cardiovascular Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 2
Special Issue Editor
Interests: cardiovascular disease; vascular surgery; biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Vascular disease (VD) remains the leading cause of morbidity and mortality worldwide. It encompasses a broad range of conditions, including localized atherosclerotic diseases such as peripheral artery disease (PAD) and carotid artery stenosis (CAS); aneurysmal pathologies such as aortic aneurysm (AA); venous disorders including chronic venous disease (CVD) and venous thromboembolism (VTE); and vascular-related wounds such as diabetic foot ulcer (DFU), venous leg ulcer (VLU), and arterial leg ulcer (ALU). Various risk factors contribute to the onset of subclinical VD, which may progress to overt clinical disease. The development of effective strategies for primary, secondary, and tertiary prevention is a critical public health priority.
In the era of precision medicine (PM), molecular biomarkers are emerging as valuable tools for early detection, risk stratification, and monitoring of individuals predisposed to VD. Recent advances in molecular biology, chemistry, and translational medicine have facilitated the identification of reliable biomarkers that support accurate diagnosis, patient stratification, and follow-up after pharmacological or surgical interventions, including vascular and endovascular procedures.
The current multidimensional approach to health and disease recognizes the need to integrate molecular sociology, an emerging interdisciplinary field that explores how molecular-level factors interact with social determinants of health. This perspective emphasizes the influence of socioeconomic status, environmental exposure, behavioral patterns, and healthcare access on gene expression, molecular pathways, and disease progression. By bridging the gap between biological and social sciences, molecular sociology contributes to a more comprehensive understanding of the etiology and progression of vascular diseases, supporting the development of more effective and equitable prevention and treatment strategies.
Today’s comprehensive approach to disease management highlights the interplay between molecular, biological, and social determinants of health, underscoring the central role of molecular sciences and biomarker research in understanding and addressing VD.
In this Special Issue, we welcome original research articles and reviews that provide novel insights into the molecular mechanisms underlying vascular disease, as well as studies focused on the development of innovative diagnostic and prognostic biomarkers linked to therapeutic strategies. Articles must include data on molecular mechanisms or pathophysiology.
Dr. Raffaele Serra
Guest Editor
Manuscript Submission Information
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Keywords
- precision medicine
- precision nursing
- biomarkers
- molecular biology
- biochemistry
- genetics
- molecular sciences
- molecular research
- vascular disease
- vascular surgery
- wounds
- diabetic foot ulcers
- peripheral artery disease
- chronic venous disease
- abdominal aortic aneurysm
- thoracic aortic aneurysm
- peripheral aneurysm
- social and molecular determinants of health
- molecular sociology
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