Molecular Advance on Skin Irritation and Inflammation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (12 March 2026) | Viewed by 666
Special Issue Editor
Special Issue Information
Dear Colleagues,
Inflammatory skin diseases represent uniquely accessible tissues, useful in decoding how epithelial stress signals shape innate and adaptive immunity. For this Special Issue, we invite original research and reviews that illuminate the molecular circuits linking keratinocytes, fibroblasts, and myeloid/lymphoid cells to clinical phenotypes and treatment response. We especially welcome studies dissecting photoimmunology and autoimmunity—such as type I interferon-driven pathways in cutaneous lupus erythematosus and dermatomyositis—as well as works on chronic wounds and neutrophilic dermatoses that reveal shared and divergent mechanisms of tissue injury and repair.
Cutting-edge methodologies are encouraged, including single-cell and spatial transcriptomics, proteomics, advanced imaging, and functional models (organoids, ex vivo human skin, and in vivo systems). Translational contributions that connect mechanism to biomarkers, patient-reported outcomes, and targeted therapies are of particular interest. We also welcome method papers and datasets that enable the reproducible analysis of complex human samples.
By bringing together mechanistic and clinically grounded studies, this Special Issue will identify actionable nodes in cytokine–chemokine networks, clarify stromal–immune crosstalk, and accelerate the development of diagnostics and therapeutics to measurably improve patients’ lives.
Dr. Nazgol-Sadat Haddadi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- photoimmunology
- keratinocyte stress
- type I interferon
- cutaneous lupus erythematosus
- der-matomyositis
- monocyte-derived dendritic cells
- fibroblast heterogeneity
- cytokine–chemokine networks
- single-cell and spatial omics
- targeted therapy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
