Special Issues

Genes publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic and Genomic Innovations for Developing Resilient Crops
edited by and
submission deadline 25 Nov 2025 | Viewed by 45 | Submission Open
Keywords: crop improvement; abiotic stress; gene function; transcriptomics; gene editing; molecular breeding
(This special issue belongs to the Section Plant Genetics and Genomics)
Genetics in Thyroid Cancer
edited by and Tomislav Jukić
submission deadline 25 Nov 2025 | Viewed by 36 | Submission Open
Keywords: genetic mutations; thyroid cancer; molecular diagnostics; risk stratification; novel therapies; MAPK/PI3K-AKT signalling; radioiodine-refractory; redifferentiation therapeutic strategies; tumour genomic profiling; targeted therapy
(This special issue belongs to the Section Molecular Genetics and Genomics)
15th Anniversary of Genes: Feature Papers in “Neurogenetics and Neurogenomics”
edited by and Micheal Palladino
submission deadline 25 Nov 2025 | Viewed by 10 | Submission Open
Keywords: genomics; neurological diseases; multi-omics studies; brain development and function; precision medicine; pathogenic mechanisms
(This special issue belongs to the Section Neurogenomics)
Diagnosis and Treatment of Inherited Breast Cancer
edited by Maja Prutki and
submission deadline 25 Nov 2025 | Viewed by 5 | Submission Open
Keywords: inherited breast cancer; germline mutations; BRCA1; BRCA2; genetic testing; risk assessment; preventive strategies; targeted therapy; personalized medicine; genetic counseling
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Genetic Mechanisms of Plant Resistance to Biotic Stress
edited by
submission deadline 25 Nov 2025 | Viewed by 5 | Submission Open
Keywords: plant diseases; biotic stress; resistance genes; genetics; genomics; plant hosts
(This special issue belongs to the Section Plant Genetics and Genomics)
Host Genetics and Pathogens in One Health Context submission deadline 25 Nov 2025 | Viewed by 1 | Submission Open
Keywords: One Health; farm animals; disease resistance; antimicrobial resistance
(This special issue belongs to the Section Animal Genetics and Genomics)
AI and Machine Learning in Cancer Genomics
edited by
submission deadline 25 Nov 2025 | Submission Open
Keywords: genomics; cancer; AI; ML; tools; signatures; biomarkers; oncology
(This special issue belongs to the Section Bioinformatics)
Insights into the Genomic and Genetic Basis of Cardiovascular Disease
edited by Marzia de Biasio and
submission deadline 10 Dec 2025 | Viewed by 4 | Submission Open
Keywords: recurrent idiopathic pericarditis and perimyocarditis; spontaneous coronary dissection; sudden idiopathic cardiac death; idiopathic atrial fibrillation; cardio-oncology and cardio toxicity of anti anti-cancer drugs
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Plant Genetics, Evolution, Cytogenetics and Cytogenomics for Biodiversity Conservation submission deadline 15 Dec 2025 | 1 articles | Viewed by 651 | Submission Open
Keywords: plant conservation; cytogenetics; cytogenomics; plant evolution; population genetics; genome evolution; chromosomal variation; polyploidy; biodiversity; genomic resources
(This special issue belongs to the Section Plant Genetics and Genomics)
Genetic and Molecular Insights into Cardiovascular Disease: From Mechanisms to Precision Medicine submission deadline 15 Dec 2025 | Viewed by 73 | Submission Open
Keywords: cardiovascular disease; genetic variants; precision medicine; epigenetics; non-coding RNAs; polygenic risk scores; mendelian randomization; biomarkers; genome-wide association studies (GWASs); molecular mechanisms
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Molecular Genetics of Stress Response in Crops
edited by Jie Zhan
submission deadline 15 Dec 2025 | Viewed by 26 | Submission Open
Keywords: crop; abiotic stresses; protein translation; regulation; molecular mechanism; plant hormones
(This special issue belongs to the Section Plant Genetics and Genomics)
Application of Molecular or Genetic Markers in Liquid Biopsy for Urogenital Cancers
edited by
submission deadline 15 Dec 2025 | Viewed by 5 | Submission Open
Keywords: liquid biopsy; extracellular vesicle; exosome; biotechnology; precision medicine/personalized medicine; diagnosis/screening; urogenital cancer
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Cattle Genetics, Genomics and Breeding: From Molecular Insights to Sustainable Production submission deadline 15 Dec 2025 | Submission Open
Keywords: bovine; Bos  taurus  taurus; Bos  taurus  indicus; genomic  selection; GWAS; multi-omics; gene editing; breeding strategies; reproductive technologies; genetic diversity; adaptation genetics; disease resistance; epigenetics; climate resilience; sustainable production; precision livestock farming
(This special issue belongs to the Section Animal Genetics and Genomics)
Feature Papers in Microbial Genetics and Genomics submission deadline 20 Dec 2025 | 1 articles | Viewed by 911 | Submission Open
Keywords: virus; bacteria; protists; parasites; genomics; transcriptomics; proteomics; genetics; drug resistance; molecular evolution; data re-analysis
(This special issue belongs to the Section Microbial Genetics and Genomics)
Molecular Mechanisms Responsible for Radiation-Induced Toxicity of Normal Tissue
edited by
submission deadline 25 Dec 2025 | 7 articles | Viewed by 22501 | Submission Open
Keywords: radioresponsive genes; inflammation; genetic markers of radiation damage; immunotherapy; radioprotectors; DNA damage and repair
(This special issue belongs to the Section Toxicogenomics)
Single-Cell and Spatial Multi-Omics in Human Diseases
edited by
submission deadline 25 Dec 2025 | Viewed by 306 | Submission Open
Keywords: single-cell omics; spatial multi-omics; pathogenesis of disease; biomarkers; computational tools; integrative biology
(This special issue belongs to the Section Bioinformatics)
Current Advances in Inherited Retinal Disease
edited by
submission deadline 25 Dec 2025 | Viewed by 80 | Submission Open
Keywords: inherited retinal diseases; retinitis pigmentosa; macular dystrophy; cone dystrophy; genotype; gene therapy; clinical trial; imaging; genetic mechanism; genome editing; phenotype
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Hereditary Traits and Diseases in Companion Animals submission deadline 25 Dec 2025 | Viewed by 61 | Submission Open
Keywords: genetic traits; hereditary diseases; companion animals; spontaneous disease models; veterinary genetics; genetic selection; breed-specific diseases
(This special issue belongs to the Section Animal Genetics and Genomics)
The Function and Molecular Mechanism for Immune Responses in Human Diseases
edited by Zsofia Banlaki
submission deadline 25 Dec 2025 | Viewed by 40 | Submission Open
Keywords: leukocyte; cytokine; immune receptor; signal transduction; gene expression; antibody-antigen; major histocompatibility complex; complement system; inflammation
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Genome Assembly and Annotation in Biology
edited by , and Mika Sakamoto
submission deadline 31 Dec 2025 | Viewed by 299 | Submission Open
Keywords: genome assembly; genome annotation; structural gene prediction; functional gene prediction; reference genomes; annotation tools and pipelines; comparative genomics
(This special issue belongs to the Section Bioinformatics)
The 15th Anniversary of Genes: Feature Papers in the "Animal Genetics and Genomics" Section submission deadline 31 Dec 2025 | Viewed by 143 | Submission Open
Keywords: applied genetics and genomics in species of economic importance; companion animal genetics and genomics; breeding and genetic selection; genetics and genomics of aquaculture species; genetics of immune response and disease resistance; genome-edited animals and animal epigenetics; animal population genetics; polymorphisms and genome annotation; genetics applied to the interaction of microbiome and genetic traits of interest; bioinformatics analysis in animal genetics; genomics and evolution; cytogenomics
(This special issue belongs to the Section Animal Genetics and Genomics)
The 15th Anniversary of Genes: Feature Papers in the Human Genomics and Genetic Diseases Section submission deadline 31 Dec 2025 | Viewed by 111 | Submission Open
Keywords: genetics of monogenic diseases and complex diseases; genotype– phenotype relationships; population genomics and genetic epidemiology; precision medicine; pharmacogenetics and pharmacogenomics; targeted genome editing; gene therapy and delivery systems; genetically engineered cell therapy; RNA- and small nucleic acid-based therapeutics; genetic testing and molecular diagnostics; biomarker development and application; genome-wide association studies; epigenetic therapy; developmental genetics; epigenetics; and epigenomics
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
The Development of Genetic Assessment for Neurotoxicity submission deadline 31 Dec 2025 | Viewed by 74 | Submission Open
Keywords: neurotoxicity; genetics; neurodegenerative disorders; mental disorders
(This special issue belongs to the Section Toxicogenomics)
Genomic Data Analysis in Human Health and Disease
edited by Ighli Di Bari and
submission deadline 31 Dec 2025 | Viewed by 65 | Submission Open
Keywords: protein modeling and structure-function prediction; variant pathogenicity prediction tools; functional annotation of genetic variants; machine learning in genomics
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
The 15th Anniversary of Genes: Feature Papers in the Population and Evolutionary Genetics and Genomics Section
edited by
submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open
Keywords: population genetics; evolutionary genomics; genetic diversity; adaptation; natural selection
(This special issue belongs to the Section Population and Evolutionary Genetics and Genomics)
15th Anniversary of Genes: Feature Papers in the “Plant Genetics and Genomics” Section submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open
Keywords: epigenetic editing; genetics; genomics; pangenome; plants; QTL mapping; QTL cloning; regulation of gene expression; transcriptome
(This special issue belongs to the Section Plant Genetics and Genomics)
15th Anniversary of Genes: Feature Papers in the “Cytogenomics” Section
edited by
submission deadline 31 Dec 2025 | Viewed by 44 | Submission Open
Keywords: molecular cytogenetics; cytogenomics; microarray; chromosome biology; karyotyping; high-throughput cytogenetics; genome organization; comparative genomics; karyomapping; optical mapping
(This special issue belongs to the Section Cytogenomics)
Research Updates in Forensic Genetics
edited by Massimo Lancia
submission deadline 31 Dec 2025 | Viewed by 40 | Submission Open
Keywords: next generation sequencing; single cell analysis; time since deposition; time since death; DNA phenotyping; biogeographic ancestry; age prediction; familial search; disaster victim identification; trace DNA contextualisation
(This special issue belongs to the Section Molecular Genetics and Genomics)
The 15th Anniversary of Genes: Feature Papers in the RNA Section submission deadline 31 Dec 2025 | Viewed by 31 | Submission Open
Keywords: tRNAs; rRNAs; mRNAs; miRNAs; lncRNAs; sRNAs; siRNAs; RNA epigenetics; RNA modifications; RNA secondary and tertiary structure; viral RNAs; RNA binding proteins; RNA transcription; RNA translation
(This special issue belongs to the Section RNA)
Next-Generation Diagnosis and Treatment of Hematologic Diseases submission deadline 15 Jan 2026 | Viewed by 86 | Submission Open
Keywords: hematologic disease; hematology; thrombosis and hemostasis; bleeding disorders; artificial intelligence; next-generation theranostics; therapeutics; diagnostics; peptide design; precision medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Veterinary Genetics and Genomics
edited by and Enikő Fehér
submission deadline 15 Jan 2026 | Viewed by 2 | Submission Open
Keywords: veterinary genetics; animal genomics; infectious diseases and disease resistance; pathogenetics; genomic selection and livestock improvement; conservation genetics; epigenetics; CRISPR gene editing; next-generation sequencing (NGS); forensic genetics; LAMP method
(This special issue belongs to the Section Animal Genetics and Genomics)
Genomics and Proteomics-Based Molecular Diagnostics and Targeted Therapies in Cancer
edited by
submission deadline 25 Jan 2026 | Viewed by 26 | Submission Open
Keywords: molecular diagnostics; targeted therapies; biomarkers; precision medicine oncology; chemotherapy; small-molecule drugs; monoclonal antibodies; cancer immunotherapy
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Genetics and Environmental Factors in Psychiatric Disorders
edited by
submission deadline 25 Jan 2026 | Viewed by 17 | Submission Open
Keywords: PGS; environmental factors; epigenetics; prenatal environmental exposures; GWAS; GxE interactions
(This special issue belongs to the Section Genes & Environments)
Novel Insights into Forensic Genetics submission deadline 31 Jan 2026 | Viewed by 88 | Submission Open
Keywords: forenscic genetics; molecular autopsy; forensic omics; post-mortem genetic testing; legal medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Computational Genomics and Bioinformatics of Cancer
edited by
submission deadline 20 Feb 2026 | Viewed by 63 | Submission Open
Keywords: cancer; data analysis; bioinformatics; complex diseases; dimensionality reduction; genetics; epigenetics; gene regulation; molecular mechanism; environmental factors
(This special issue belongs to the Section Bioinformatics)
Unraveling the Genetic Tapestry of Human Populations: New Insights from Population Genetics and Identification in Anthropology submission deadline 25 Feb 2026 | Viewed by 45 | Submission Open
Keywords: human genetic diversity; population genetics; migration patterns; admixture; isolated populations; ancestry reconstruction; anthropological genomics; biomedical relevance; forensic identification
(This special issue belongs to the Section Population and Evolutionary Genetics and Genomics)
Genetics and Genomics of Aging and Longevity, Pathways and Response to Nutrients in Mammals and Simple Model Organisms
edited by
submission deadline 30 Mar 2026 | Viewed by 17 | Submission Open
Keywords: nutrigenetics; nutrigenomics; signal transduction
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
Diagnosis, Management and Therapy of Rare Diseases
edited by Giorgia Girotto
submission deadline 30 Apr 2026 | Viewed by 70 | Submission Open
Keywords: rare and ultrarare genetic diseases; genetic mechanisms; gene-tailored management; personalized therapeutic approaches
(This special issue belongs to the Section Human Genomics and Genetic Diseases)
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