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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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A New Era in Diagnosis: From Biomarkers to Artificial Intelligence, 2nd Edition

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1569 | Submission Open

Keywords: biomarkers; diagnosis; personalized medicine; therapeutic strategies; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Chronic Kidney Diseases: Diagnosis, Management, and Prognosis

edited by

Xujie Zhou

submission deadline 31 Dec 2026 | Viewed by 1502 | Submission Open

Keywords: chronic kidney diseases; IgA nephropathy; biomarkers; molecular mechanisms; therapeutic innovation; personalized medicine; translational research

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Prognostic and Predictive Biomarkers, 4th Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1429 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1326 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Whole-Body PET/CT: From Diagnosis to Prognosis

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1312 | Submission Open

Keywords: whole-body PET/CT; diagnosis; prognosis; human diseases; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Oral and Maxillofacial Surgery: Diagnosis and Management

edited by Kenji Yamagata

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1299 | Submission Open

Keywords: oral and maxillofacial surgery; oral diseases; oral cancer; jaw deformity; orthognathic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Women’s Cardiovascular Health: Advances in Diagnosis, Screening, and Risk Prediction

edited by

Jasjit S. Suri

and

Luca Saba

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1291 | Submission Open

Keywords: artificial intelligence; women’s cardiovascular health; diagnosis; screening; risk prediction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1220 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Fetal Diagnosis and Therapy: 2nd Edition

edited by Elisa Montaguti and Camilla Dionisi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1210 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | Viewed by 1204 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases

edited by

Liangjing Lu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1154 | Submission Open

Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Advances in Orthodontics and Dentistry

edited by

Antonino Lo Giudice

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1064 | Submission Open

Keywords: CBCT facial scanning; oral imaging; orthodontics; digital dentistry; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Eye Disease, Fifth Edition

edited by

Jae-Ho Han

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1046 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Technologies for Lung Disease Detection and Clinical Assessment

edited by Scott Matson and

Joshua Jay Reicher

submission deadline 31 Dec 2026 | 2 articles | Viewed by 972 | Submission Open

Keywords: medical imaging; artificial intelligence (AI); radiology; machine learning (ML)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Prostate Cancer: Innovations in Diagnosis and Risk Stratification

edited by Biren Saraiya

submission deadline 31 Dec 2026 | 1 articles | Viewed by 949 | Submission Open

Keywords: prostate cancer; diagnostics; therapeutics; molecular targets; Prostate Specific Membrane Antigen (PSMA); risk stratification; radioligand therapy; multimodal therapy; clinical guidelines

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Accurate Diagnosis and Management of Infectious and Respiratory Diseases

edited by

Marco Goeijenbier

submission deadline 31 Dec 2026 | 2 articles | Viewed by 658 | Submission Open

Keywords: infectious and respiratory diseases; viral and bacterial pathogens; multiplex molecular panels; rapid diagnostic tests; intensive care units

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Cancer Diagnosis and Intervention

edited by Vlad Alexandru Gâta

submission deadline 31 Dec 2026 | 1 articles | Viewed by 618 | Submission Open

Keywords: diagnostic; precision oncology; artificial intelligence; radiomics; molecular biomarkers; interventional oncology; personalized medicine; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 31 Dec 2026 | 1 articles | Viewed by 603 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis, Prognosis, and Management of the Musculoskeletal System

edited by

Massimiliano Leigheb

Alessandro de Sire

and Cesar de Cesar Netto

submission deadline 31 Dec 2026 | 1 articles | Viewed by 558 | Submission Open

Keywords: musculoskeletal system; diagnostic tools; prognosis; artificial intelligence; augmented reality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Laboratory Diagnosis—2nd Edition

edited by

Giuseppe Lippi

and Camilla Mattiuzzi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 556 | Submission Open

Keywords: laboratory diagnosis; biomarkers; clinical chemistry; laboratory analysis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Emerging Diagnostic Techniques and Therapeutic Strategies in Urological Oncology

edited by

Francesco Chierigo

submission deadline 31 Dec 2026 | Viewed by 536 | Submission Open

Keywords: prostate cancer; screening; biomarkers; genetic testing; imaging; PSMA; artificial intelligence; radical prostatectomy; radiotherapy; hormonal therapies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

From Early Diagnosis to Therapy Response: Machine Learning Driven Biomarker Discovery

edited by Wenjie Shi and Rudy Leon De Wilde

submission deadline 31 Dec 2026 | 1 articles | Viewed by 533 | Submission Open

Keywords: machine learning; biomarker discovery; early diagnosis; liquid biopsy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Pulmonary Adenocarcinoma

edited by

Cesar A. Moran

submission deadline 31 Dec 2026 | Viewed by 461 | Submission Open

Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Deep Learning and Large Models in Ophthalmic Innovations

edited by

Yanwu Xu

Weihua Yang

and Huihui Fang

submission deadline 31 Dec 2026 | Viewed by 438 | Submission Open

Keywords: Artificial Intelligence in ophthalmology; multimodal learning; foundation models; ophthalmic imaging; eye disease diagnosis and treatment

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Endoscopic Ultrasound: Diagnostic and Therapeutic Innovations

edited by

Andrada Seicean

submission deadline 31 Dec 2026 | Viewed by 432 | Submission Open

Keywords: endoscopic ultrasound (EUS); diagnostic and therapeutic innovations; minimally invasive interventions; EUS-guided tissue acquisition; advanced imaging techniques; multidisciplinary gastroenterology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathogenesis, Diagnosis, and Management of Rheumatic Disease: Progress and Challenges

edited by Miguel Ángel González-Gay

submission deadline 31 Dec 2026 | Viewed by 415 | Submission Open

Keywords: rheumatic disease; systemic vasculitis; rheumatoid arthritis; metabolic syndrome; atherosclerosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic and Prognostic Tools in Gynecological Cancer

edited by

Ahmad Sayasneh

submission deadline 31 Dec 2026 | Viewed by 393 | Submission Open

Keywords: gynaecological cancer; diagnostic imaging; artificial intelligence; molecular biomarkers; prognostic models; surgical navigation; precision oncology; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Computed Tomography Imaging in Medical Diagnosis, Third Edition

edited by

Fabio Sandomenico

submission deadline 31 Dec 2026 | 1 articles | Viewed by 381 | Submission Open

Keywords: computed tomography; medical diagnosis; imaging; internal organs; bones; soft tissue; blood vessels

(This special issue belongs to the Section Medical Imaging and Theranostics)

Medical Microbiology and Infection: Diagnosis and Management

edited by Hsinyao Wang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 380 | Submission Open

Keywords: medical microbiology; infectious diseases; diagnostic microbiology; infection management; antimicrobial susceptibility testing; non‑antibiotic therapies; clinical microbiology; diagnostic innovation

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Gastrointestinal Endoscopy: Diagnostic Applications and Safety Evaluation

edited by

Giacomo Emanuele Maria Rizzo

Lucía Guilabert

and Sara Nikolic

submission deadline 31 Dec 2026 | Viewed by 380 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; luminal endoscopy; procedural safety; risk assessment; adverse events; sedation protocols

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis and Management of Hepatitis

edited by

Qi Wang

submission deadline 31 Dec 2026 | Viewed by 377 | Submission Open

Keywords: viral hepatitis; hepatitis B virus hepatitis; drug-induced liver injury; autoimmune hepatitis; metabolic-associated fatty liver disease; alcoholic liver disease; diagnosis; follow-up management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Selected Papers From the 1st International Online Conference on Diagnostics [IOCDi 2026]

edited by

Giorgio Treglia

submission deadline 31 Dec 2026 | Viewed by 348 | Submission Open

Keywords: imaging diagnosis; pathology diagnosis; molecular diagnosis; clinical diagnosis; laboratory medicine; point-of-care diagnosis; artificial intelligence

Data Science and Artificial Intelligence in Laboratory Medicine

edited by

Fernando Marques-Garcia

submission deadline 31 Dec 2026 | Viewed by 309 | Submission Open

Keywords: artificial intelligence; data science; algorithm; laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Liquid Biopsy and Molecular Diagnostics in Neuro-Oncology

edited by Santiago Cabezas-Camarero and Juan Manuel Sepúlveda-Sánchez

submission deadline 31 Dec 2026 | Viewed by 302 | Submission Open

Keywords: liquid biopsy; biofluids; biomarkers; molecular techniques; gliomas; neuro-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Approaches to Vascular Diseases Diagnosis and Management

edited by

Paolo Perini

and

Chiara Martini

submission deadline 31 Dec 2026 | Viewed by 289 | Submission Open

Keywords: vascular imaging; vascular surgery; aortic aneurysm; peripheral arterial disease; venous disease; image-guided therapy; artificial intelligence; 3D printing; medical devices; vascular complications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopic Diagnosis and Management of Tumors

edited by

Longjun He

submission deadline 31 Dec 2026 | Viewed by 285 | Submission Open

Keywords: endoscopy; tumor diagnosis; endoscopic therapy; endoscopic ultrasound; artificial intelligence; early cancer detection; minimally invasive surgery; precision oncology; molecular imaging; translational research

(This special issue belongs to the Section Biomedical Optics)

Clinical Diagnostics and Management in the ICU

edited by

Silvia De Rosa

and Sergio Lassola

submission deadline 31 Dec 2026 | 2 articles | Viewed by 267 | Submission Open

Keywords: intensive care unit; hemodynamic monitoring; acute kidney injury; sepsis and septic shock; clinical diagnostics; predictive biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnostics in Renal Transplantation and Transplant Complications

edited by

Cheng Yang

submission deadline 31 Dec 2026 | Viewed by 258 | Submission Open

Keywords: renal transplantation; precision diagnostics; allograft rejection; non-invasive monitoring; biomarkers; multi-omics; kidney transplant complications; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Analytical Techniques in Microbial and Biomarker Research

edited by Hariom Yadav,

Siddabasave Gowda B. Gowda

and

Shu-Ping Hui

submission deadline 31 Dec 2026 | Viewed by 249 | Submission Open

Keywords: LC-MS; GC-MS; NMR; spectroscopy; microbiology; clinical; diagnostics

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Precision Diagnosis in Musculoskeletal Disorders: Current and Future Directions

edited by

Yuichi Yoshii

submission deadline 31 Dec 2026 | Viewed by 230 | Submission Open

Keywords: precision diagnosis; musculoskeletal imaging; artificial intelligence; quantitative imaging biomarkers; automated morphological analysis; predictive modeling; 3D patient-specific modeling; digital twin; image-guided diagnosis; personalized musculoskeletal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis, Prognosis, and Management of Urinary Disease—2nd Edition

edited by

Nicola Longo

and

Massimiliano Creta

submission deadline 31 Dec 2026 | Viewed by 213 | Submission Open

Keywords: urinary disease; diagnosis; prognosis; kidney disease; prostate disease; malignant diseases like kidney cancer, bladder cancer and prostate cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Perspectives in the Diagnosis of Gastroenterological Diseases

edited by Reena Sidhu

submission deadline 31 Dec 2026 | Viewed by 212 | Submission Open

Keywords: small bowel; bleeding; Crohn’s disease; endoscopy; coeliac disease; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Machine Learning in Disease Diagnosis

edited by

Chi-Jie Lu

and

Yi-Wei Kao

submission deadline 31 Dec 2026 | Viewed by 205 | Submission Open

Keywords: machine learning; disease diagnosis; medical/healthcare informatics; multimodal learning; explainable AI (XAI); federated learning; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Point-of-Care and At-Home Diagnostics for Infectious Diseases

edited by Gregory J. Tobin and Ke Du

submission deadline 31 Dec 2026 | Viewed by 186 | Submission Open

Keywords: infectious agents; at-home diagnostic; point-of-care diagnostic; pathogen surveillance; digital health; novel detection technologies; low-resource settings

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Precision Oncology: Integrating Histopathology, Immunohistochemistry, and Molecular Diagnostics

edited by

Tomonori Kawasaki

submission deadline 31 Dec 2026 | Viewed by 172 | Submission Open

Keywords: biomarker; cancer; carcinoma; cytology; diagnosis; fluorescence in situ hybridization; gene; growth factor receptor; histology; hormone receptor; immunohistochemistry; molecular pathology; neoplasm; next-generation sequencing; oncology; pathology; PCR; prognosis; treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Lung Monitoring in Critical Care

edited by Lorenzo Ball

submission deadline 31 Dec 2026 | Viewed by 167 | Submission Open

Keywords: lung monitoring; critical care; mechanical ventilation; diagnosis; imaging

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Advances in Diagnosis and Treatment of Thyroid Cancer

edited by

Chang Myeon Song

submission deadline 31 Dec 2026 | Viewed by 166 | Submission Open

Keywords: thyroid cancer; diagnosis; robotic thyroid surgery; thyroidectomy; molecular diagnostics; minimally invasive surgery; risk stratification; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Early Diagnosis and Imaging-Guided Management of Oral Diseases: Advances and Perspectives

edited by

Matthieu Renaud

submission deadline 31 Dec 2026 | Viewed by 159 | Submission Open

Keywords: early diagnosis; oral diseases; medical imaging; artificial intelligence; biomarkers; multimodal diagnosis; inflammation; tissue monitoring

(This special issue belongs to the Section Medical Imaging and Theranostics)

From Innovation to Clinical Practice: Anticipating the New Era of AI-Driven Laboratory Medicine

edited by Edda Russo

submission deadline 31 Dec 2026 | Viewed by 150 | Submission Open

Keywords: artificial intelligence (AI); laboratory medicine; data integration; clinical validation; diagnostic strategies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Innovative Diagnostic Strategies for Inherited Metabolic Diseases

edited by Radha Ramachandran

submission deadline 31 Dec 2026 | Viewed by 146 | Submission Open

Keywords: inherited metabolic; diagnostic; prognostic monitoring; personalised genetic functional omics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 401-450 on page 9 of 13.

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