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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Traumatic Brain Injury and Associated Neurological and Neuropsychiatric Disorders: Diagnosis/Prognosis and Therapeutics

edited by

Theodosis Kalamatianos

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1367 | Submission Open

Keywords: traumatic brain injury; neurological and neuropsychiatric disorders; clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Dermatologic Diagnostics: Integrating Dermoscopy, Imaging, and Non-Surgical Therapies

edited by

Carmen Cantisani

and

Norbert Kiss

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1352 | Submission Open

Keywords: dermoscopy; clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Biomedical Optics)

Sports Related Musculoskeletal Disorders: Diagnosis, Treatment and Management

edited by

Jin Hyuck Lee

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1292 | Submission Open

Keywords: orthopedics; rehabilitation medicine; musculoskeletal disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Obstetric Ultrasound

edited by

Florian Recker

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1254 | Submission Open

Keywords: obstetric ultrasound; prenatal diagnosis; fetal imaging; 3D/4D ultrasound; doppler ultrasound; artificial intelligence; ultrasound education; maternal– fetal medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Beyond the Image: Cardiac Imaging at the Service of the Patient

edited by

George Koulaouzidis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1251 | Submission Open

Keywords: cardiac imaging; multimodality; patient outcomes; artificial intelligence; compassion in medicine; quantitative imaging; image-guided therapy; translational cardiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Medical Image Processing

edited by Zhiwei Wang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1188 | Submission Open

Keywords: medical image processing; foundation models; multimodal learning; computer-aided diagnosis; image segmentation and registration; generative AI; clinical decision support; representation learning; explainable and trustworthy AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Pulmonary and Critical Care Medicine: Contemporary Diagnosis and Management

edited by

Te-Chun Shen

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1114 | Submission Open

Keywords: chronic obstructive pulmonary disease (COPD); asthma; interstitial lung disease; lung cancer; respiratory infection; obstructive sleep apnea; respiratory failure; acute respiratory distress syndrome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Imaging in Dermatology

edited by

Victor Desmond Mandel

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1113 | Submission Open

Keywords: optical imaging; dermatology; reflectance confocal microscopy; optical coherence tomography; multiphoton microscopy; Raman spectroscopy; super-resolution microscopy; hyperspectral imaging

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in Hearing and Audiology Science: Diagnosis and Management, 2nd Edition

edited by

Yu Sun

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1109 | Submission Open

Keywords: hearing loss; genetic deafness; cochlear implants; hair cell regeneration; central auditory processing; vestibular disorders; tinnitus; intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis of Corneal and Retinal Diseases

edited by

Cristina Nicula

and Alina Popa-Cherecheanu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1062 | Submission Open

Keywords: imaging diagnosis; corneal diseases; retinal diseases; optical coherence tomography (OCT); ultrasound

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Urologic Oncology: Biomarkers, Diagnosis, and Management—2nd Edition

edited by

Roberto Contieri

submission deadline 30 Jun 2026 | 1 articles | Viewed by 985 | Submission Open

Keywords: urologic oncology; biomarkers; diagnosis; management; urothelial carcinoma; prostate cancer; kidney cancer; testis cancer; penile cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Acute Pancreatitis

edited by Farid Froghi and Mikael Hans Sodergren

submission deadline 30 Jun 2026 | 1 articles | Viewed by 937 | Submission Open

Keywords: acute pancreatitis; risk stratification; advanced imaging; biomarkers; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Digestive System Diseases, Second Edition

edited by Jialing Huang

submission deadline 30 Jun 2026 | 1 articles | Viewed by 886 | Submission Open

Keywords: digestive system; pathology; liver transplantation; diagnosis; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Arthroscopy Techniques in Diagnosis and Treatment 2026

edited by Maristella Francesca Saccomanno and

Andrea De Fazio

submission deadline 30 Jun 2026 | 1 articles | Viewed by 850 | Submission Open

Keywords: arthroscopy; arthroscopy techniques; sports medicine; diagnosis; biological therapies; PROMS

(This special issue belongs to the Section Biomedical Optics)

Recent Applications of Electrodiagnosis in Neuromuscular Diseases

edited by

Donggyu Lee

submission deadline 30 Jun 2026 | 1 articles | Viewed by 779 | Submission Open

Keywords: electrodiagnosis; neuromuscular diseases; EMG (electromyography); nerve conduction studies; electrical stimulation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Thyroid Nodule and Cancer Diagnostics

edited by

Kwangsoon Kim

submission deadline 30 Jun 2026 | 1 articles | Viewed by 747 | Submission Open

Keywords: thyroid nodule; thyroid cancer; diagnostic imaging; molecular diagnostics; ultrasound elastography; Fine-Needle Aspiration (FNA); artificial intelligence; risk stratification; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging of Long-COVID (Post-Acute Sequelae of COVID, PASC) and Post-Infectious Syndromes

edited by

Eric Guedj

submission deadline 30 Jun 2026 | 1 articles | Viewed by 615 | Submission Open

Keywords: long COVID; post-acute sequelae of COVID (PASC); COVID-19; SARS-CoV-2; post-infectious syndromes; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); medical imaging; nuclear medicine; PET; SPECT; MRI; CT; ultrasound; imaging biomarkers; metabolism; neuroinflammation; microvascular dysfunction; multisystem involvement; diagnosis; prognosis; rehabilitation; functional impairment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Arthroscopy Techniques in Diagnosis and Treatment in 2025–2026

edited by

Jae-Sung Yoo

submission deadline 30 Jun 2026 | 1 articles | Viewed by 505 | Submission Open

Keywords: arthroscopic diagnostics; nerve compression syndromes; small joint arthroscopy; endoscopic spine evaluation; minimally invasive diagnostic techniques

(This special issue belongs to the Section Biomedical Optics)

Laboratory Investigations in Nephrology

edited by

Marijn Speeckaert

submission deadline 30 Jun 2026 | Viewed by 495 | Submission Open

Keywords: nephrology; laboratory diagnostics; novel biomarkers; chronic kidney disease; renal pathology; artificial intelligence and machine learning

(This special issue belongs to the Section Clinical Laboratory Medicine)

Innovative Biomarkers and Diagnostic Strategies in Immune-Mediated Diseases

edited by

Marcos López Hoyos

submission deadline 30 Jun 2026 | Viewed by 421 | Submission Open

Keywords: immune-mediated diseases; innovative biomarkers; diagnostic strategies; classification criteria; laboratory techniques

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Applications of Artificial Intelligence and Non-Invasive Electrocardiograms in Disease Diagnosis

edited by

Constantinos Bakogiannis

and Samuel L. Johnston

submission deadline 30 Jun 2026 | Viewed by 392 | Submission Open

Keywords: artificial intelligence (AI); non-invasive electrocardiogram (ECG); disease diagnosis; medical imaging analysis; machine learning; deep learning; cardiovascular diseases; pattern recognition; data analytics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Pulmonary Adenocarcinoma

edited by

Cesar A. Moran

submission deadline 30 Jun 2026 | Viewed by 390 | Submission Open

Keywords: pulmonary adenocarcinoma; diagnosis; molecular testing; imaging analysis; detection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis of Infectious Diseases: Advances and Challenges, 2nd Edition

edited by

Hung-Sheng Shang

submission deadline 30 Jun 2026 | Viewed by 388 | Submission Open

Keywords: infectious diseases; diagnostic techniques; laboratory innovation; diagnostic accuracy; global health; disease detection; diagnostic challenges; medical technology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Molecular Classification and Precision Diagnostics in Glioma: Recent Advances

edited by Ruichao Chai

submission deadline 30 Jun 2026 | Viewed by 367 | Submission Open

Keywords: glioma; molecular classification; molecular pathology; biomarker; molecular testing

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Current Imaging in Forensic Medicine

edited by Francesca Maglietta

submission deadline 30 Jun 2026 | Viewed by 313 | Submission Open

Keywords: post-mortem computed tomography (PMCT); post-mortem magnetic resonance imaging (PMMRI); post-mortem CT angiography (PMCTA); micro-computed tomography (micro-CT); virtual autopsy; injury biomechanics and reconstruction; forensic age assessment; disaster victim identification (DVI); detection of natural disease and sudden cardiac death; custodial deaths

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Valvular Heart Disease and Myocardial Function, Second Edition

edited by

Vasileios Kamperidis

submission deadline 30 Jun 2026 | Viewed by 310 | Submission Open

Keywords: echocardiography; speckle tracking; 3D echo; cardiac MRI; cardiac perfusion imaging; aortic stenosis or regurgitation; mitral stenosis or regurgitation; tricuspid stenosis or regurgitation; pulmonary stenosis or regurgitation; transcatheter valvular treatment; surgical valvular treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Latest Innovations in Interventional Oncology

edited by

Pierleone Lucatelli

and

David C. Madoff

submission deadline 30 Jun 2026 | Viewed by 309 | Submission Open

Keywords: contrast-enhanced ultrasound (CEUS); hybrid PET-MRI oncology imaging; optical coherence tomography (OCT) diagnostics; AI-driven lesion segmentation; radiomics-based tumor profiling; liquid biopsy innovations; endovascular biomarker sampling; molecular imaging specificity; real-time tumor characterization; image-guided diagnostic paradigms

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI and Machine Learning in the Diagnosis and Personalized Treatment of Inflammatory and Autoimmune Diseases

edited by Jorge Sotos Mateo

submission deadline 30 Jun 2026 | Viewed by 304 | Submission Open

Keywords: artificial intelligence; machine learning; personalized medicine; inflammatory diseases; autoimmune disorders; predictive modeling; medical diagnostics; biomarkers

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Epigenetic Markers and Cytokines to Increase the Prevention of the Development of Invasive Cancer

edited by Attila Louis Major

submission deadline 30 Jun 2026 | Viewed by 260 | Submission Open

Keywords: cytokines; methylation; histone proteins; non-coding RNA; oncogenic development; cancer prevention

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Gastrointestinal Inflammatory Disorders

edited by

Antoni Stadnicki

submission deadline 30 Jun 2026 | Viewed by 243 | Submission Open

Keywords: gut; small intestine; large bowel; endoscopy; medical imaging; inflammation; Helicobacter pylori; oesophagitis; gastritis; celiac disease; inflammatory bowel disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Neuroendocrine Tumors—2nd Edition

edited by Federica Alessandra Cavalcoli

submission deadline 30 Jun 2026 | Viewed by 242 | Submission Open

Keywords: neuroendocrine neoplasm; pancreatic neuroendocrine neoplasm; gastric neuroendocrine neoplasm; small-bowel neuroendocrine neoplasm; appendicular neuroendocrine neoplasm; lung neuroendocrine neoplasm; functional imaging; cross-sectional imaging; endoscopic ultrasound

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Beyond ctDNA: New Approaches in Oncology Diagnostics for Earlier Detection of Cancer

edited by Kevin M. Elias and Abigail S. McElhinny

submission deadline 30 Jun 2026 | Viewed by 240 | Submission Open

Keywords: early detection; multi-omics; liquid biopsy; solid tumors; screening; surveillance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Advances in Gastrointestinal Endoscopy

edited by Riccardo Vasapolli

submission deadline 30 Jun 2026 | Viewed by 240 | Submission Open

Keywords: gastrointestinal endoscopy; advanced imaging; artificial intelligence; early detection; preneoplastic lesions; therapeutic endoscopy; EUS/ERCP; bariatric endoscopy

(This special issue belongs to the Section Biomedical Optics)

Surgical Diagnosis and Management of Inflammatory Diseases in Hepatobiliary and Pancreatic Systems

edited by

Roberto Cotellese

and

Federico Selvaggi

submission deadline 30 Jun 2026 | Viewed by 212 | Submission Open

Keywords: surgical diagnosis; diagnostic biomarkers; intraoperative imaging; pathology; risk stratification; disease differentiation; prognostic assessment; hepatobiliary inflammation; pancreatic inflammation; minimally invasive biopsy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Diagnostics in Renal Transplantation and Transplant Complications

edited by

Cheng Yang

submission deadline 30 Jun 2026 | Viewed by 183 | Submission Open

Keywords: renal transplantation; precision diagnostics; allograft rejection; non-invasive monitoring; biomarkers; multi-omics; kidney transplant complications; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 30 Jul 2026 | Viewed by 2271 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Essentials of Imaging Diagnosis in Pulmonary Diseases: Techniques and Clinical Practice

edited by Chiara Romei

submission deadline 30 Jul 2026 | 1 articles | Viewed by 1897 | Submission Open

Keywords: pulmonary imaging; CT; MRI; and PET/CT imaging for lung diseases; quantitative imaging; artificial intelligence and machine learning; ventilation and perfusion imaging; clinical application; diagnosis; personalized medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 Jul 2026 | 9 articles | Viewed by 29125 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition

edited by

Jesús Ramírez-Bermúdez

submission deadline 31 Jul 2026 | 6 articles | Viewed by 23053 | Submission Open

Keywords: neuropsychiatric disorders; autism; mania; depression; imaging; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Sarcoidosis: From Diagnosis to Management

edited by Huzaifa I. Adamali

submission deadline 31 Jul 2026 | 5 articles | Viewed by 19571 | Submission Open

Keywords: sarcoidosis; granulomas; interstitial lung disease; lung; heart; skin; liver; neurological; joints; diagnosis imaging; PET/CT; chest X-ray

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Frontline of Breast Imaging

edited by

Gary J. Whitman

submission deadline 31 Jul 2026 | 8 articles | Viewed by 15676 | Submission Open

Keywords: breast imaging; breast ultrasound; mammography; digital breast tomosynthesis; digital mammography; contrast-enhanced mammography; breast MRI; molecular breast imaging; imaging-guided interventional breast procedures

(This special issue belongs to the Section Medical Imaging and Theranostics)

Skin and Cutaneous Adnexal Tumors: Diagnosis and Management—2nd Edition

edited by

Andreas Manios

and

Dimitra Koumaki

submission deadline 31 Jul 2026 | 4 articles | Viewed by 13104 | Submission Open

Keywords: cutaneous adnexal tumors; follicular and sebaceous tumors; sweat gland tumors

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Updates on Stroke: Diagnosis and Management

edited by Joseph Domenico Gabrieli

submission deadline 31 Jul 2026 | 3 articles | Viewed by 10276 | Submission Open

Keywords: ischemic stroke; atheromatous disease; thrombolysis; machine learning; neurovascular anatomy; imaging; thrombectomy; diagnosis and management; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Echocardiography Applications in Cardiovascular Diseases

edited by

Corina Maria Vasile

submission deadline 31 Jul 2026 | 5 articles | Viewed by 9883 | Submission Open

Keywords: echocardiography; congenital heart disease; imaging techniques; artificial intelligence; automatization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy

edited by Cristiano Spada and Daniele Salvi

submission deadline 31 Jul 2026 | 6 articles | Viewed by 9667 | Submission Open

Keywords: gastrointestinal endoscopy; therapeutic endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); artificial intelligence; small bowel capsule endoscopy; bariatric endoscopy

(This special issue belongs to the Section Biomedical Optics)

Advances in Mental Health Diagnosis and Screening, 2nd Edition

edited by Elaine Chapman

submission deadline 31 Jul 2026 | 6 articles | Viewed by 9175 | Submission Open

Keywords: mental health; diagnosis; screening; marker; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Bacterial Infections and Antimicrobial Resistance: Diagnosis and Management

edited by

Georgina Tzanakaki

submission deadline 31 Jul 2026 | 6 articles | Viewed by 8557 | Submission Open

Keywords: bacterial infections; antimicrobial resistance (AMR); diagnostic innovations; molecular diagnostics; antimicrobial stewardship; multidrug-resistant pathogens; alternative therapies; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Large Language Models in Medical Diagnostics: Advancing Clinical Practice, Research, and Patient Care

edited by

Tim Duong

submission deadline 31 Jul 2026 | 6 articles | Viewed by 8392 | Submission Open

Keywords: large language models; diagnostic; prognosis; decision support; clinical practice

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Technologies and Tools Used for Risk Assessment of Diseases

edited by

Chih-Wei Huang

submission deadline 31 Jul 2026 | 4 articles | Viewed by 7998 | Submission Open

Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Imaging of the Future: From the Standardisation of Diagnostic Processes to Artificial Intelligence

edited by

Emanuele David

submission deadline 31 Jul 2026 | 1 articles | Viewed by 7370 | Submission Open

Keywords: artificial intellicence; technologies; ultrasound; MRI; CT; angiography; mammography

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

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