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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biomarkers of Gynecological Cancers

edited by

Kelechi Njoku

submission deadline 30 Sep 2025 | 1 articles | Viewed by 921 | Submission Open

Keywords: biomarkers; gynecological cancer; cervical cancer; ovarian cancer; uterine cancer; endometrial cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Optical Coherence Tomography in Non-Invasive Diagnostic Imaging

edited by

Carmen Cantisani

and

Sandra Schuh

submission deadline 30 Sep 2025 | 1 articles | Viewed by 864 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging

(This special issue belongs to the Section Biomedical Optics)

Deep Learning and Multimodal Large Language Models in Tumor/Cancer Diagnosis, Prediction and Prognosis

edited by

Steven L. Fernandes

submission deadline 30 Sep 2025 | 1 articles | Viewed by 823 | Submission Open

Keywords: diagnosis; prognosis; tumor/cancer; deep learning; multimodal large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Hot Topics in Modern and Personalized Pathology

edited by

Sergejs Isajevs

submission deadline 30 Sep 2025 | 1 articles | Viewed by 759 | Submission Open

Keywords: personalized diagnostics and tissue biomarkers; molecular pathology; digital pathology; oncological pathology; and rare cancer studies; tumor diagnostics and tumor biomarkers; immunohistochemistry; molecular and ultrastructural pathology; laboratory medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Lung Imaging: Highlights of Recent Research and Clinical Applications

edited by

Stefano Palmucci

submission deadline 30 Sep 2025 | 1 articles | Viewed by 729 | Submission Open

Keywords: diagnosis; prognosis; lung imaging; markers; clinical practice and patient care

(This special issue belongs to the Section Medical Imaging and Theranostics)

Epidemiology, Diagnostic Tools, and Vaccination Strategies for Emerging Infectious Diseases: Preparing for the Next Pandemic

edited by Luis Pablo Cruz-Hervert,

Maria-Eugenia Jimenez-Corona

and Renata Alejandra Báez Saldaña

submission deadline 30 Sep 2025 | Viewed by 710 | Submission Open

Keywords: emerging infectious diseases; COVID-19; influenza; epidemiological surveillance; diagnostic innovations; vaccination strategies; vaccine-preventable diseases; drug resistance; infectious disease modeling; global health preparedness

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Molecular Diagnosis and Medical Management of Cardiovascular Diseases

edited by

Yiqing Yang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 588 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; coronary artery disease; arrhythmia; cardiomyopathy; essential hypertension; stroke; molecular genetics; epidemiology; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Evaluation and Management of Developmental Disabilities

edited by

Meir Lotan

submission deadline 30 Sep 2025 | 1 articles | Viewed by 543 | Submission Open

Keywords: developmental disabilities; early intervention; diagnostic assessment; therapeutic strategies; neurodevelopmental disorders; personalized care; multidisciplinary approach; family-centered support

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Musculoskeletal (MSK) Radiology

edited by Haron Obaid

submission deadline 30 Sep 2025 | Viewed by 516 | Submission Open

Keywords: musculoskeletal; MRI; synchrotron; artificial intelligence; ultrasound; robotics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Alzheimer’s Disease Diagnosis—2nd Edition

edited by

Mohammad Shahadat Hossain

submission deadline 30 Sep 2025 | Viewed by 489 | Submission Open

Keywords: Alzheimer’ s disease; artificial intelligence; machine learning; explainable AI; expert systems; computer vision; deep learning; diagnosis; cognition; brain informatics; neurodegenerative disorder

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

An Update on Molecular Diagnostics in Prostate Cancer

edited by

Giuseppe Lucarelli

and

Francesco Lasorsa

submission deadline 30 Sep 2025 | Viewed by 474 | Submission Open

Keywords: imaging; molecular biomarkers; diagnosis; prognosis; risk stratification

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Chronic Wounds: Diagnosis and Management

edited by

Thomas E. Serena

and Kylie Sandy-Hodgetts

submission deadline 30 Sep 2025 | Viewed by 446 | Submission Open

Keywords: chronic wound; imaging; biomarker; point-of-care techniques

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Renal Cell Cancer

edited by

Giuseppe Lucarelli

submission deadline 30 Sep 2025 | Viewed by 423 | Submission Open

Keywords: renal cell carcinoma; biomarkers; nephrectomy; diagnosis; treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Integration of Genomics and Diagnostics in AI-Driven Precision Oncology

edited by Wenjie Shi

submission deadline 30 Sep 2025 | Viewed by 412 | Submission Open

Keywords: machine learning; artificial intelligence; genomics; precision oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic and Prognostic Biomarkers in Prostate Cancer

edited by Vittorio Fasulo

submission deadline 30 Sep 2025 | Viewed by 404 | Submission Open

Keywords: prostate cancer; biomarker; biopsy; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging Biomarkers for Pachychoroid Spectrum Disease

edited by

Rui Hua

Feng Wen

and

Meixia Zhang

submission deadline 30 Sep 2025 | Viewed by 393 | Submission Open

Keywords: pachychoroid spectrum disease; peripapillary pachychoroid syndrome; central serous chorioretinopathy; pachychoroid neovasculopathy; polypoidal choroidal vasculopathy; pachychoroid pigment epitheliopathy; focal choroidal excavation; macular neovascularization; optical coherence tomography angiography; indocyanine green angiography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Coronary Artery Disease: Diagnosis and Management

edited by Joost F. ter Woorst

submission deadline 30 Sep 2025 | Viewed by 348 | Submission Open

Keywords: coronary artery disease; EKG (electrocardiogram); Echo (echocardiography); CXR (chest X-ray); stress test; cardiac catheterization; CABG (coronary artery bypass graft surgery); OPCAB (off-pump coronary artery bypass); Endo-CAB; Robo-CAB; female sex

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 30 Sep 2025 | Viewed by 326 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Cardiac MRI

edited by

Magalie Viallon

submission deadline 30 Sep 2025 | Viewed by 280 | Submission Open

Keywords: diagnosis; cardiac MRI; prognosis; patient care; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Sleep Disorders Using Machine Learning Approaches, 2nd Edition

edited by

Alaa Sheta

, Shyam Subramanian and

Salim R. Surani

submission deadline 30 Sep 2025 | Viewed by 259 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; sleep disorders; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition

edited by

Silvia Martu

Liliana-Georgeta Foia

and

Maria Alexandra Mârțu

submission deadline 30 Sep 2025 | Viewed by 208 | Submission Open

Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Translational Research Advances in the Diagnosis of Hematological Diseases

edited by

Robert S. Ohgami

submission deadline 30 Sep 2025 | Viewed by 189 | Submission Open

Keywords: hematologic diseases; genomic diagnostics; digital pathology; biomarker; laboratory diagnostics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Radiation Oncology

edited by Xianjin Dai

submission deadline 30 Sep 2025 | Viewed by 181 | Submission Open

Keywords: artificial intelligence in radiation therapy; deep learning-based auto-segmentation; AI-driven radiotherapy; treatment planning; adaptive radiation therapy with AI radiomics and machine learning for outcome prediction; multi-modal image analysis in radiotherapy; reinforcement learning for dose optimization uncertainty; quantification in AI for radiation oncology; trustworthy and explainable AI in cancer treatment; AI-integrated radiotherapy; workflow automation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of Electrodiagnosis in Neuromuscular Diseases

edited by

Donggyu Lee

submission deadline 30 Sep 2025 | Viewed by 179 | Submission Open

Keywords: electrodiagnosis; neuromuscular diseases; EMG (electromyography); nerve conduction studies; electrical stimulation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 30 Sep 2025 | Viewed by 179 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome– host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Diagnosis of Hypertension

edited by Vasileios Kotsis

submission deadline 30 Sep 2025 | Viewed by 164 | Submission Open

Keywords: hypertension; diagnosis; biomarkers; digital health; early detection

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advances in Diagnosis and Management of Breast Cancer

edited by Wing Lok Wendy Chan

submission deadline 30 Sep 2025 | Viewed by 161 | Submission Open

Keywords: breast cancer; diagnosis; treatment; personalized medicine; imaging techniques; immunotherapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Enhancements in Screening Pathways for Early Detection of Lung Cancer

edited by

Paolo Albino Ferrari

and

Antonio Maccio

submission deadline 30 Sep 2025 | Viewed by 158 | Submission Open

Keywords: lung cancer screening; early diagnosis; multidisciplinary pathways; liquid biopsy; exhaled breath condensate; molecular imaging; sub-lobar resection; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiometabolic Disease: Diagnosis and Management

edited by Muhammad Shariq Usman

submission deadline 30 Sep 2025 | Viewed by 144 | Submission Open

Keywords: cardiometabolic disease; diagnosis; management; diabetes; obesity; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

The Role of Diagnostic Imaging in Musculoskeletal Pain

edited by Ian Young

submission deadline 30 Sep 2025 | Viewed by 127 | Submission Open

Keywords: diagnostic imaging; musculoskeletal pain; imaging techniques (or imaging modalities); diagnostic accuracy; clinical applications; pain management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Nuclear Medicine and Molecular Imaging in Cancer Diagnosis, Therapy, and Treatment Assessment

edited by

Sara Harsini

submission deadline 30 Oct 2025 | 2 articles | Viewed by 2186 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET/CT; theranostics; cancer diagnosis; treatment monitoring

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning and Multimodal Feature Fusion for Advanced Medical Imaging Diagnosis

edited by

Sarmad Maqsood

and

Rytis Maskeliūnas

submission deadline 30 Oct 2025 | 1 articles | Viewed by 1042 | Submission Open

Keywords: deep learning; feature fusion; medical imaging; artificial intelligence in healthcare; diagnostic imaging; multimodal data integration; explainable AI; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Medical Imaging: Challenges and Opportunities

edited by Morten Bo Søndergaard Svendsen

submission deadline 30 Oct 2025 | Viewed by 291 | Submission Open

Keywords: deep learning; artificial intelligence; medical imaging; endoscopy; image segmentation; medical image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Cardiothoracic Imaging: Recent Techniques and Applications in Diagnostics, Second Edition

edited by

Giacomo Sica

submission deadline 31 Oct 2025 | 11 articles | Viewed by 34608 | Submission Open

Keywords: emergency; cardiac imaging; thoracic imaging; aorta; MRI; CT; radiomics; artificial intelligence; ILD

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—2nd Edition

edited by

Farhan Akram

submission deadline 31 Oct 2025 | 15 articles | Viewed by 28902 | Submission Open

Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Cardiovascular Diseases

edited by Fabrizio Guarracini and Cristina Giannattasio

submission deadline 31 Oct 2025 | 21 articles | Viewed by 26094 | Submission Open

Keywords: cardiovascular disease; risk stratification; preventive cardiology; hypertension; dyslipidaemias; heart failure management; interventional cardiology; coronary artery disease; arrythmias

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning in Medical Image Segmentation and Diagnosis

edited by Rahib Abiyev

submission deadline 31 Oct 2025 | 11 articles | Viewed by 25939 | Submission Open

Keywords: deep learning in medical diagnosis; medical imaging and deep learning; data mining and deep learning; emerging deep learning techniques and diagnosis; deep learning for the classification of lesions and disease; deep learning for segmentation; denoising; and super resolution; deep learning for signal analysis; learning mechanisms in deep neural networks; ensemble learning; stacked networks; medical informatics; computer-assisted diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Assessment and Diagnosis of Cognitive Disorders

edited by

Elena Cecilia Rosca

submission deadline 31 Oct 2025 | 7 articles | Viewed by 21888 | Submission Open

Keywords: cognitive disorders; neurology; neuroimaging; biomarkers; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Oct 2025 | 12 articles | Viewed by 18317 | Submission Open

Keywords: diagnosis; precision medicine; predictive diagnostics; therapeutic strategies; biomarkers; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Ultrasound

edited by

Rute Santos

submission deadline 31 Oct 2025 | 11 articles | Viewed by 18141 | Submission Open

Keywords: quantitative ultrasound techniques; ultrasound tissue characterization; ultrasound-guided therapy or intervention; clinical applications of diagnostic ultrasound; ultrasound imaging processing; diagnostic ultrasound devices

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Heart Disease, 2nd Edition

edited by

Yuli Huang

submission deadline 31 Oct 2025 | 8 articles | Viewed by 15437 | Submission Open

Keywords: heart disease; coronary artery disease; arrhythmia; heart failure; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Sports Medicine

edited by

Luis Manuel Martínez Aranda

and

Jacobo Á. Rubio Arias

submission deadline 31 Oct 2025 | 6 articles | Viewed by 14751 | Submission Open

Keywords: diagnosis; sports injuries; injury frequency; ligaments; strain; tendon injuries; sport-related concussion; injury treatment; return to play; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Vasculitis

edited by

Alicia Rodríguez-Pla

submission deadline 31 Oct 2025 | 8 articles | Viewed by 14530 | Submission Open

Keywords: vasculitis; advances; updates; management; treatment; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis, Prognosis and Management of Hematologic Malignancies

edited by

Rossella Cacciola

Emma C. Cacciola

, Alessandra Romano and Alessandro Allegra

submission deadline 31 Oct 2025 | 6 articles | Viewed by 12587 | Submission Open

Keywords: leukemia; myeloproliferative neoplasms; myeloma; lymphoma

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 Oct 2025 | 7 articles | Viewed by 12117 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Head and Neck Disease

edited by

Cristiana Lo Nigro

submission deadline 31 Oct 2025 | 11 articles | Viewed by 12114 | Submission Open

Keywords: head and neck disease; oral and maxillofacial disease; throat cancer; thyroid disease; otolaryngology tumor

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Fetal Cardiology

edited by Maciej Słodki

submission deadline 31 Oct 2025 | 5 articles | Viewed by 11615 | Submission Open

Keywords: fetal cardiology; echocardiography; medical imaging; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Endoscopy in Diagnosis of Gastrointestinal Disorders—2nd Edition

edited by

Miguel Mascarenhas

submission deadline 31 Oct 2025 | 8 articles | Viewed by 11612 | Submission Open

Keywords: endoscopy; gastroenterology; coloproctology; digestive healthcare; artificial intelligence; digestive oncology; colonoscopy; capsule endoscopy; upper endoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis of Skin Disease

edited by

Gerardo Cazzato

submission deadline 31 Oct 2025 | 8 articles | Viewed by 10812 | Submission Open

Keywords: dermatology; dermatopathology; skin diseases; neoplastic diseases; inflammatory dermatopathology; CTCL; melanoma; squamous cell carcinoma; basal cell carcinoma; infectious diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Thyroid Disorders

edited by Vladan Zivaljevic

submission deadline 31 Oct 2025 | 5 articles | Viewed by 10520 | Submission Open

Keywords: thyroid disease management; diagnosis of thyroid disease; novel procedures; thyroid disorders; thyroid cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

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