Skin and Cutaneous Adnexal Tumors: Diagnosis and Management—2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 3960

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Guest Editor
Department of Surgical Oncology, School of Medicine, University Hospital Heraklion, Heraklion, Greece
Interests: skin cancer; malignant melanoma; plastic and reconstructive surgery; adnexal tumors
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Guest Editor
Dermatology Department, University Hospital of Heraklion, 71110 Heraklion, Greece
Interests: skin cancer; melanoma and non-melanoma skin cancer; skin surgery
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Special Issue Information

Dear Colleagues,

Cutaneous adnexal tumors (ATs) enclose a large group of benign and malignant tumors, deriving from the hair follicle, sebaceous glands, eccrine, or apocrine glands. Because of the extensive overlap in clinical features of cutaneous adnexal tumors, biopsy is essential for diagnosis. Immunohistochemical stains may be useful for the diagnosis of tumors with ambiguous histopathologic features. The goal of this Special Issue entitled “Skin and Cutaneous Adnexal Tumors: Diagnosis and Management” is to review the clinical and histopathological features, diagnosis, and management of cutaneous adnexal tumors and related syndromes. Contributions to the clinical and histopathological diagnosis and management of these tumors are welcome. Furthermore, articles related to syndromes associated with cutaneous adnexal tumors such as Brooke–Spiegler syndrome, Cowden syndrome, Birt–Hogg–Dubé syndrome, Muir–Torre syndrome, and familial cylindromatosis are also invited to be submitted for consideration for publication.

Dr. Andreas Manios
Dr. Dimitra Koumaki
Guest Editors

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Keywords

  • cutaneous adnexal tumors
  • follicular and sebaceous tumors
  • sweat gland tumors

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Related Special Issue

Published Papers (2 papers)

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Review

20 pages, 11203 KiB  
Review
Diagnosis and Management of Malignant Epithelial Nail Unit Tumors
by Matilde Iorizzo, Laura Vollono and Bertrand Richert
Diagnostics 2024, 14(21), 2379; https://doi.org/10.3390/diagnostics14212379 - 25 Oct 2024
Cited by 1 | Viewed by 1830
Abstract
Background: Malignant epithelial nail unit tumors pose significant diagnostic and therapeutic challenges due to their clinical presentation often mimicking benign conditions and due to the need to preserve as much nail unit function as possible during surgery. Early detection is crucial, even [...] Read more.
Background: Malignant epithelial nail unit tumors pose significant diagnostic and therapeutic challenges due to their clinical presentation often mimicking benign conditions and due to the need to preserve as much nail unit function as possible during surgery. Early detection is crucial, even if none of these tumors represent a life-threatening disease. Objectives: This review focus on squamous cell carcinoma, verrucous carcinoma, eccrine porocarcinoma, onychocytic carcinoma, basal cell carcinoma, malignant onychopapilloma, malignant onycholemmal cyst and onycholemmal carcinoma. Methods: Existing literature on the aforementioned tumors has been revised and synthesized. Results: Clinical presentation, pathology, diagnostic procedures, risk factors and the challenges associated with surgical management have been described in detail. Conclusions: Malignant epithelial tumors of the nail unit require careful evaluation and management due to their complex presentation. Early detection and an informed surgical approach are essential to improve patient outcomes and minimize complications. Full article
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19 pages, 2762 KiB  
Review
Diagnosis and Management of Scalp Metastases: A Review
by Stephano Cedirian, Luca Rapparini, Andrea Sechi, Bianca Maria Piraccini and Michela Starace
Diagnostics 2024, 14(15), 1638; https://doi.org/10.3390/diagnostics14151638 - 30 Jul 2024
Cited by 2 | Viewed by 1529
Abstract
Scalp metastases (SMs) are particularly noteworthy, representing around 4–7% of cutaneous neoplasms in this region of the body, possibly due to its rich blood supply. Diagnosis of SMs involves a systematic approach encompassing oncologic history, clinical examination, dermoscopy, imaging, and histopathological assessment. Clinical [...] Read more.
Scalp metastases (SMs) are particularly noteworthy, representing around 4–7% of cutaneous neoplasms in this region of the body, possibly due to its rich blood supply. Diagnosis of SMs involves a systematic approach encompassing oncologic history, clinical examination, dermoscopy, imaging, and histopathological assessment. Clinical presentations of SM can vary, but dermoscopy reveals unique vascular patterns aiding in diagnosis. Imaging, particularly MRI and CT, and histopathological evaluation are mandatory for definitive diagnosis. Treatment strategies vary depending on tumor characteristics and staging, ranging from surgical excision to systemic therapies like chemotherapy or radiotherapy. Multimodal approaches tailored to individual cases yield optimal outcomes. The diagnostic tools available do not always allow SMs to be diagnosed, and often the lack of knowledge on the part of oncologists in suspecting SMs can delay an early diagnosis. This review provides clinicians with a practical guide for the timely diagnosis and management of SM, emphasizing the importance of a multidisciplinary approach and personalized treatment strategies for improved patient outcomes. Full article
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