Recent Applications of Electrodiagnosis in Neuromuscular Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 March 2027 | Viewed by 964

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Guest Editor
Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu 42415, Republic of Korea
Interests: electrodiagnosis in neuromuscular diseases
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Special Issue Information

Dear Colleagues,

We can announce this Special Issue, entitled "Recent Applications of Electrodiagnosis in Neuromuscular Diseases", which will explore the extensive range of applications of electrodiagnostic techniques in the field of neuromuscular diseases. This Special Issue will provide a comprehensive overview of how electrodiagnosis, including nerve conduction studies and electromyography, is utilized to diagnose, assess, and manage various neuromuscular disorders. By showcasing the latest research findings and clinical cases, this Special Issue will highlight the crucial role of electrodiagnosis in improving patient outcomes and advancing our understanding of neuromuscular function. This Special Issue will serve as a valuable resource for healthcare professionals, researchers, and students, offering insights into the latest advancements and challenges in this dynamic field.

Dr. Donggyu Lee
Guest Editor

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Keywords

  • electrodiagnosis
  • neuromuscular diseases
  • EMG (electromyography)
  • nerve conduction studies
  • electrical stimulation

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Published Papers (1 paper)

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Research

10 pages, 536 KB  
Article
Association Between Sclerostin and Sarcopenia-Related Functional Decline in Older Women
by Dong Gyu Lee, Jong Ho Lee and Eunjung Kong
Diagnostics 2026, 16(2), 272; https://doi.org/10.3390/diagnostics16020272 - 14 Jan 2026
Cited by 1 | Viewed by 630
Abstract
Background: Sclerostin, an osteocyte-derived glycoprotein, plays a key role in bone metabolism by inhibiting the Wnt/β-catenin signaling pathway. While it is a recognized therapeutic target in osteoporosis, its relationship with sarcopenia remains unclear. This study aimed to investigate the associations between serum sclerostin [...] Read more.
Background: Sclerostin, an osteocyte-derived glycoprotein, plays a key role in bone metabolism by inhibiting the Wnt/β-catenin signaling pathway. While it is a recognized therapeutic target in osteoporosis, its relationship with sarcopenia remains unclear. This study aimed to investigate the associations between serum sclerostin levels, sarcopenia, and osteoporosis in older women. Methods: We conducted a cross-sectional study of 79 postmenopausal women aged ≥65 years. Sarcopenia was defined based on grip strength and appendicular skeletal muscle mass (ASM), osteoporosis was diagnosed according to femoral T-scores, and serum sclerostin levels were measured using ELISA. Associations with clinical variables and bone mineral density (BMD) were evaluated using correlation and logistic regression analyses. Results: Sclerostin levels were significantly higher in women with sarcopenia (p = 0.036) and exhibited a negative correlation with grip strength (r = −0.298, p = 0.008) but not with ASM. Positive correlations were found between sclerostin and multiple femoral BMD parameters. In a logistic regression analysis, sclerostin was modestly associated with sarcopenia (p = 0.045); however, no significant association was observed with osteoporosis (p = 0.257). Conclusions: Elevated sclerostin levels are associated with reduced muscle strength and sarcopenia in older women, independent of muscle mass, indicating that sclerostin may reflect a functional decline in musculoskeletal health. Muscle strength should therefore be considered when interpreting sclerostin’s clinical implications in aging populations. Full article
(This article belongs to the Special Issue Recent Applications of Electrodiagnosis in Neuromuscular Diseases)
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