Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Biomedical Optics".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 650

Special Issue Editors


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Guest Editor
1. Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy
2. Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
3. Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy
Interests: colorectal cancer; endoscopy; capsule endoscopy; gastroenterology; gastrointestinal endoscopy; gastrointestinal diseases; colonoscopy; esophageal diseases

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Guest Editor Assistant
Department of Gastroenterology and Endoscopy, Fondazione Poliambulanza Istituto Ospedaliero, 25124 Brescia, Italy
Interests: gastrointestinal endoscopy; gastrointestinal diseases; capsule endoscopy; disorders of gut–brain interaction

Special Issue Information

Dear Colleagues,

In recent years, the field of gastrointestinal endoscopy has witnessed remarkable progress, driven by technological innovation and the integration of artificial intelligence (AI) into clinical practice. These developments have significantly enhanced both diagnostic accuracy and therapeutic efficacy across a range of GI diseases.

Notably, AI has demonstrated considerable promise in improving the early detection of Barrett’s neoplasia and colonic precancerous lesions. Similarly, the expanding role of endoscopic ultrasound (EUS) is redefining the management of malignant obstructions, offering both diagnostic precision and therapeutic utility. Innovations in small bowel capsule endoscopy have contributed to reduced reading times while maintaining strong diagnostic performance. Furthermore, bariatric endoscopy is emerging as a minimally invasive and effective strategy in weight management, with important clinical implications.

These transformative changes underscore the need for ongoing education and adaptation among endoscopists as the endoscopy suite increasingly incorporates sophisticated tools and technologies.

This Special Issue, "Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy", will showcase cutting-edge developments across the endoscopic spectrum, from foundational techniques in gastroscopy and colonoscopy to advanced procedures including ERCP, therapeutic EUS, AI-enhanced imaging, and bariatric endoscopic interventions.

We welcome the submission of original research articles and comprehensive reviews. Case reports or series—particularly those featuring literature reviews—or viewpoints will also be considered, so long as they explore novel applications of endoscopic technologies or address underexplored yet clinically relevant topics.

We look forward to reading your valuable contributions to this Special Issue, which should inform, inspire, and support continued advancement in the field of gastrointestinal endoscopy.

Prof. Dr. Cristiano Spada
Guest Editor

Dr. Daniele Salvi
Guest Editor Assistant

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastrointestinal endoscopy
  • therapeutic endoscopy
  • endoscopic ultrasound (EUS)
  • endoscopic retrograde cholangiopancreatography (ERCP)
  • artificial intelligence
  • small bowel capsule endoscopy
  • bariatric endoscopy

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Published Papers (1 paper)

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Research

12 pages, 1633 KB  
Article
Kyoto Classification-Based Predictive Factors Associated with the Development of Gastric Cancer After Helicobacter pylori Eradication: A Prospective Multicenter Observational Study
by Shun Takayama, Osamu Dohi, Ryusuke Horie, Takeshi Yasuda, Tomoko Ochiai, Naoto Iwai, Eiko Imamoto, Tomohisa Takagi, Osamu Handa, Hideyuki Konishi, Takashi Ando, Yuji Naito, Toshiki Takemura and Yoshito Itoh
Diagnostics 2025, 15(18), 2376; https://doi.org/10.3390/diagnostics15182376 - 18 Sep 2025
Viewed by 316
Abstract
Background/Objectives: This study aimed to identify specific endoscopic findings associated with the development of GC following successful H. pylori eradication. Methods: This prospective multicenter observational study included patients who underwent annual surveillance endoscopy after successful H. pylori eradication therapy between September [...] Read more.
Background/Objectives: This study aimed to identify specific endoscopic findings associated with the development of GC following successful H. pylori eradication. Methods: This prospective multicenter observational study included patients who underwent annual surveillance endoscopy after successful H. pylori eradication therapy between September 2013 and June 2019. Endoscopic findings were evaluated one year after eradication therapy and analyzed using the Kyoto Classification of Gastritis to identify factors associated with GC development. Results: A total of 465 patients were included, including 49 patients with GC and 416 patients without GC. At the initial endoscopic assessment (median, 0.96 years post-eradication), emergence of map-like redness and invisible regular arrangement of collecting venule (RAC) as independent predictors of GC (map-like redness: hazard ratio [HR], 2.561; 95% confidence interval [CI], 1.362–4.572; p = 0.003; invisible RAC: HR, 3.131; 95% CI, 1.078–9.091; p = 0.036). Patients with map-like redness or invisible RAC showed a significantly higher incidence of GC than those without map-like redness or invisible RAC (p < 0.001 and p < 0.001, respectively). Notably, map-like redness and visible RAC appeared in 13% and 28.4% of cases within the first year after eradication, respectively. Conclusions: Map-like redness and invisible RAC were identified as independent predictors of GC following H. pylori eradication and may serve as early predictive indicators, appearing within one year of successful eradication. This finding underscores the importance of early surveillance endoscopy in identifying patients at elevated risk for GC. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy)
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