Advances in Pediatric Neuro-Oncology 2.0

Dear Colleagues,

Central nervous system (CNS) tumors constitute the second most common cancer diagnosed worldwide each year in the pediatric population. They account for approximately 25% of childhood malignancies, representing the second leading cause of cancer death in children, adolescents, and young adults less than 20 years of age. In addition, the morbidity associated with CNS tumors and their treatment may significantly impact the quality of life and personal achievements of cured patients, conditioning physical deficits, as well as neuropsychological and neuroendocrine sequelae. In the last 20 years, there has been significant progress in the molecular knowledge of pediatric CNS tumors. Optimizing the treatment of childhood CNS tumors therefore remains a tremendously challenging task, requiring a multidisciplinary approach involving many pediatric specialists, as well as the support of molecular biologists and pharmacologists.

This Special Issue will examine innovative approaches to the diagnosis and treatment of children with CNS tumors.

We welcome the submission of original research articles focusing on the following: (i) advancing new concepts in neurosurgical approach; (ii) neuroradiological novelty; (iii) new potential targeted therapies; (iv) clinical trials, radiotherapy, and proton beam therapy; (v) quality of life during and after treatment; (vi) cancer predisposition syndromes; and (vii) long-term effects of treatments. We welcome the submission of review articles on the use of narrative medicine in pediatric neuro-oncology within this Special Issue.

Dr. Angela Mastronuzzi
Dr. Andrea Carai
Guest Editors

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