Extracellular Vesicles in Cancer Diagnosis

Dear Colleagues,

Extracellular vesicles play a critical role in the communication between cells. They act as cargo carriers, with their cargo consisting of many molecules derived from the cells that they originate from. Among other molecules, proteins, RNA, microRNAs and non-coding RNAs have generated particular interest among researchers, as their exosome-mediated transfer to recipient cells is believed to confer many survival advantages. Research shows that tumor cell-derived extracellular vesicles promote tumor progression through local and systemic effects, and functionally contribute to malignant processes such as metastasis, immunosuppression, angiogenesis, and drug resistance. Besides their functional effects in the tumor microenvironment, extracellular vesicles have been shown to serve as attractive biomarkers in cancers.

We welcome any articles that investigate extracellular vesicles as cancer biomarkers, and the use of exosomes for cancer diagnosis and prognosis.

Dr. Irina Matei
Guest Editor

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