Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Translational Aspects of Cell Signaling
edited by
submission deadline 15 Apr 2026 | Viewed by 78 | Submission Open
Keywords: cell signaling; drug development; prognostic markers; bioinformatics; translational research
Cellular Metabolism and Hormonal Signaling in Colorectal Cancer: Biomarkers and Therapeutic Opportunities
edited by Jibran Sualeh Muhammad
submission deadline 15 Apr 2026 | Viewed by 58 | Submission Open
Keywords: colorectal cancer; metabolic reprogramming; gut microbiome– metabolite interactions; therapy resistance; hormonal signaling
Neurobiology of Sleep
edited by
submission deadline 15 Apr 2026 | Viewed by 33 | Submission Open
Keywords: sleep-wake regulation; neural circuits; glial biology; neurometabolism; sleep disorders; aging; neuropathology; astrocytes; GABAergic neurons
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Molecular Mechanisms Studies of the Adrenal Gland
edited by Wen-Jun Shen, Fredric B. Kraemer and Salman Azhar
submission deadline 15 Apr 2026 | Viewed by 30 | Submission Open
Keywords: adrenal zonation; steroid hormones; steroidogenesis; congenital adrenal hyperplasia; hyperaldosteronism; Cushing’ s syndrome
Novel Therapeutic Targets and Approaches, Genetic Markers and Signaling Pathways in Neoplasms submission deadline 20 Apr 2026 | 11 articles | Viewed by 30817 | Submission Open
Keywords: cancer; neoplasms; personalized medicine; genetic markers; next-generation sequencing (NGS); whole-genome sequencing; signaling pathways in cancer; novel therapeutic targets; drug development
(This special issue belongs to the Section Cell and Gene Therapy)
Recent Advances in Novel Cell and Gene Therapies for the Treatment of Immune Diseases
edited by Qingdong Guan
submission deadline 20 Apr 2026 | 2 articles | Viewed by 5665 | Submission Open
Keywords: cell therapy; gene therapy; chimeric antigen receptor T cells; T cell receptor-engineered T cells; tumor-infiltrating lymphocytes; hematopoietic stem cells; chimeric antigen receptor NK cells; induced pluripotent stem cells; mesenchymal stem/stromal cells; immune regulatory cells
(This special issue belongs to the Section Cellular Immunology)
Chromosomal Instability in Health and Disease
edited by Anna V. Roschke
submission deadline 20 Apr 2026 | 3 articles | Viewed by 5635 | Submission Open
Keywords: chromosomal instability; aneuploidy; polyploidy; cancer evolution; chromosomal instability and aneuploidy in embryonic development; chromosomal instability and polyploidy in evolutionary process; somatic aneuploidy in senescence and ageing
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Advancements in Research on hiPSC-Derived Cells
edited by Akhilesh Kumar
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1621 | Submission Open
Keywords: hiPSCs; hematopoietic progenitors; T cells; NK cells; cardiac cells; B cells; macrophages; neutrophiles; CRISPR/Cas9 technology; genetic engineering
(This special issue belongs to the Section Stem Cells)
pH Sensing, Signalling, and Regulation in Cellular Processes 
edited by Maike Glitsch
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1002 | Submission Open
Keywords: extra- and intracellular pH; pH sensing; signaling; and regulation; pH-dependent receptors; proton signaling; ion channels; G-protein-coupled receptors; cell biology and function; physiological and pathological processes; aging; cancer; inflammation; and so on; novel therapeutic strategies and targets
(This special issue belongs to the Section Cell Signaling)
Mesenchymal Stem/Stromal Cell Therapies: Innovations in Regenerative Medicine and Translational Applications
edited by Giandomenico Amico and Paolo Elia Cappella
submission deadline 20 Apr 2026 | Viewed by 229 | Submission Open
Keywords: mesenchymal stem cells (MSCs); stromal cells; microvesicles; exosomes; extracellular vesicles (EVs); immunomodulatory properties; bone marrow; adipose tissue; Wharton’ s jelly; cord blood; placenta; amnion
(This special issue belongs to the Section Stem Cells)
Atherosclerosis and Thrombosis: Molecular and Pathological Research Advance submission deadline 20 Apr 2026 | Viewed by 109 | Submission Open
Keywords: atherosclerosis; thrombosis; molecular mechanisms; translational research; precision medicine
(This special issue belongs to the Section Cellular Pathology)
Cellular and Molecular Mechanisms of Microglia/Macrophages in the Nervous System
edited by Emanuela Paldino
submission deadline 20 Apr 2026 | Viewed by 70 | Submission Open
Keywords: microglia; macrophages; neurological disorders
Signalling Mechanisms Regulating Cardiac Fibroblast Function
edited by Haofei Wang and
submission deadline 20 Apr 2026 | Viewed by 59 | Submission Open
Keywords: cardiac fibroblasts; myofibroblast activation; extracellular matrix remodeling; fibrosis; intercellular communication; mechanotransduction; single-cell and spatial insights; regeneration; therapeutic targeting
Stress-Induced Acute Immune Activation and Its Biological Consequences
edited by Ana Cicvaric
submission deadline 20 Apr 2026 | Viewed by 35 | Submission Open
Keywords: stress-induced immune signaling; acute immune activation; innate immune cell activation; cytokine response; cellular stress responses; inflammation and homeostasis
Regulatory Factors and Signaling Pathways of Anti-Tumor Immune Responses
edited by
submission deadline 20 Apr 2026 | Viewed by 31 | Submission Open
Keywords: anti-tumor immunity; immunotherapy; immune checkpoint blockade; immune receptor and ligand; immune evasion; tumor immune microenvironment; inflammation; T-cell activation and inhibition; myeloid-derived suppressor cell; macrophage; dendritic cell
(This special issue belongs to the Section Cellular Immunology)
Identifying Functional Genomics and Pathways in Cancer Pathogenesis and Therapy Resistance
edited by and Ramkrishna Mitra
submission deadline 25 Apr 2026 | 2 articles | Viewed by 2828 | Submission Open
Keywords: functional genomics; cancer signaling pathways; targeted therapy; drug resistance; tumor microenvironment; oncogenomics; acquired resistance; tumor mutations
(This special issue belongs to the Section Cellular Pathology)
Regulation of Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) in Angiogenesis
edited by Alessandra Loda and
submission deadline 25 Apr 2026 | 1 articles | Viewed by 2564 | Submission Open
Keywords: vascular endothelial growth factor (VEGF); VEGF receptors (VEGFRs); angiogenesis; endothelial cells; anti-angiogenic therapies; VEGFR inhibitors
Retinal Pigmented Epithelium (RPE) and the Choroid: Players and Partners for Vision
edited by and Janet R. Sparrow
submission deadline 25 Apr 2026 | Viewed by 559 | Submission Open
Keywords: retinal pigment epithelium; photoreceptor cell; choroid; Bruch’ s membrane; neural retina; visual cycle; phagocytosis; secretion; organelles; mitochondria; retinoid; melanin; albinism; age-related macular degeneration
(This special issue belongs to the Section Tissues and Organs)
Molecular and Cellular Insights into Platelet Function, 2nd Edition submission deadline 25 Apr 2026 | Viewed by 47 | Submission Open
Keywords: platelet; wound healing; fibrinolysis; regeneration and tissue remodeling; angiogenesis; lymphatic development; inflammation and immunity
Stem Cells in Action: Unlocking the Potential of Next-Generation Therapies
edited by George G. Koliakos
submission deadline 25 Apr 2026 | Viewed by 45 | Submission Open
Keywords: stem cell biology; differentiation and niche interaction; secretome/extracellular vesicles; organoids and disease modeling; regenerative medicine and tissue repair; immunomodulation and antimicrobial function; cell-based therapies and  cGMP translation; scaffold and biomaterial integration
(This special issue belongs to the Section Stem Cells)
Gene Editing Using Synthetic Nucleic Acids
edited by Debmalya Bhunia
submission deadline 25 Apr 2026 | Viewed by 38 | Submission Open
Keywords: gene editing; synthetic nucleic acids; genetic diseases; targeted gene therapy; antisense binding
(This special issue belongs to the Section Cell and Gene Therapy)
Unlocking the Secrets Behind Drug Resistance at the Cellular Level submission deadline 30 Apr 2026 | 5 articles | Viewed by 15388 | Submission Open
Keywords: molecular mechanisms; effective treatments; drug tests; bacterial resistance; chemoresistance
(This special issue belongs to the Section Cellular Immunology)
Eosinophils and Their Role in Allergy and Related Diseases
edited by
submission deadline 30 Apr 2026 | 5 articles | Viewed by 7662 | Submission Open
Keywords: eosinophils; asthma; allergy; inflammation; anti-eosinophil biologics; interleukin-5; interleukin-5 receptor; degranulation; mediator release
(This special issue belongs to the Section Cellular Immunology)
Research on T Cells in Skin Inflammatory Disorders
edited by and Qing-Sheng Mi
submission deadline 30 Apr 2026 | 1 articles | Viewed by 7098 | Submission Open
Keywords: T cell; vitiligo; atopic dermatitis; T cell lymphoma
(This special issue belongs to the Section Cellular Immunology)
Control of Gene Expression by Co-Transcriptional Processes in Cell Homeostasis and Cell Fate Specification: Second Edition
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 3540 | Submission Open
Keywords: gene transcription; transcription elongation; RNA processing; RNA modification; RNA transport; lncRNA; histone modification; biomolecular condensates; diseases associated with dysregulation of gene regulation
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Pathogenesis and Novel Therapies in Epithelial Cancers
edited by Jung Wook Park and Sanjeevram Dhandapani
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1957 | Submission Open
Keywords: transformation; malignant; oncogene; tumor suppressor; molecular mechanisms; epigenetic; metabolic; immune; biomarkers; personalized medicine; primary cells; small-molecule inhibitor
(This special issue belongs to the Section Cellular Pathology)
Advancements in Cardiac Metabolism
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1786 | Submission Open
Keywords: cardiovascular disease; metabolism; fatty acids; heart failure; mitochondrial dysfunction
(This special issue belongs to the Section Cells of the Cardiovascular System)
Cellular Mechanisms and Targeted Therapy of Acute Myeloid Leukemia
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1718 | Submission Open
Keywords: Acute Myeloid Leukemia (AML); molecular targets; gene therapy; drug resistance; targeted therapy; leukemia stem cells; oncogenic mutations; apoptosis; cell cycle regulation
(This special issue belongs to the Section Cellular Pathology)
Immune Cells from Pluripotent Stem Cells
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1487 | Submission Open
Keywords: pluripotent stem cells; T cells; B cells; macrophages; natural killer (NK) cells; dendritic cells; megakaryocytes; platelets
(This special issue belongs to the Section Stem Cells)
Advances in Cardiomyocyte and Stem Cell Biology in Heart Disease
edited by Ki Ho Park
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1379 | Submission Open
Keywords: cardiomyocytes; stem cells; heart disease; regenerative medicine; ion channels; protein therapeutics; bioengineering; molecular biology
(This special issue belongs to the Section Cells of the Cardiovascular System)
The Artificial Intelligence to the Rescue of Cancer Research submission deadline 30 Apr 2026 | 1 articles | Viewed by 1336 | Submission Open
Keywords: cancer research; artificial intelligence; personalized medicine; multi-omics data integration; AI-driven drug discovery; precision medicine
(This special issue belongs to the Section Cell Methods)
Mechanisms Underlying Cell Growth and Development
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 873 | Submission Open
Keywords: cell growth; cell development; cell differentiation; cell cycle; mitosis; meiosis; molecular rearrangements; chromosomes; gene expression
Role of Gamma Delta T Cells in Immunotherapy
edited by and Wenwei Tu
submission deadline 30 Apr 2026 | Viewed by 376 | Submission Open
Keywords: gamma delta T cells; adoptive cell therapy; chimeric antigen receptors; bispecific antibodies; cancer immunotherapy; tumor microenvironment; phosphoantigens; butyrophilin 2A1/3A1; virus infection; multidrug-resistant bacteria; extracellular vesicles
(This special issue belongs to the Section Cellular Immunology)
Advances in Bacterial Cell Biophysics: Metabolic Engineering and Host Interactions
edited by Shahid Khan
submission deadline 30 Apr 2026 | Viewed by 331 | Submission Open
Keywords: bacterial cell biophysics; mechanical properties; biophysical techniques; host interactions; metabolic engineering
Spatial Biology: Decoding Cellular Complexity in Tissues submission deadline 30 Apr 2026 | Viewed by 331 | Submission Open
Keywords: spatial biology; spatial tissue profiling; proteomics; transcriptomics; cell and tissue
(This special issue belongs to the Section Tissues and Organs)
Synaptic Dysregulation in Nervous System Disorders
edited by Pragya Goel
submission deadline 30 Apr 2026 | Viewed by 305 | Submission Open
Keywords: synapses; synaptic transmission; synaptic plasticity; neurodegeneration; neuropsychiatric disorders; neurodevelopmental diseases
(This special issue belongs to the Section Cells of the Nervous System)
Psilocybe Mushrooms Constituents—Therapeutic Implications
edited by and Janet Schloss
submission deadline 30 Apr 2026 | Viewed by 144 | Submission Open
Keywords: Psilocybe mushrooms; psilocybin; pre-clinical research; neurodegeneration
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Interleukin-1 Signaling in Cancer: Novel Mechanisms and Therapeutic Opportunities
edited by Afshan Fathima Nawas and
submission deadline 30 Apr 2026 | Viewed by 138 | Submission Open
Keywords: interleukin-1 signaling; tumor microenvironment; inflammatory pathways; cytokine networks; cancer cell proliferation; epigenetic regulation in cancer; non-coding RNAs; immune modulation; cancer metabolism
Advances in Liquid Biopsy for Early Detection and Monitoring of Cancer
edited by Nicola Normanno, and
submission deadline 30 Apr 2026 | Viewed by 128 | Submission Open
Keywords: ctDNA; circulating tumor cells; microRNAs; exosomes; methylation; fragmentomics; early detection; minimal residual disease; artificial intelligence
Molecular Mechanisms Underlying Inflammatory Pain
edited by
submission deadline 30 Apr 2026 | Viewed by 65 | Submission Open
Keywords: molecular mechanisms; inflammatory pain; nociception; neuronal sensitization; neuroimmune interactions
Glycosylation and Glycoproteins in Human Disease
edited by and
submission deadline 30 Apr 2026 | Viewed by 53 | Submission Open
Keywords: glycobiology; glycosylation; glycoproteins; glycolipids; glycan biomarkers; congenital disorders of glycosylation (cdg); immune modulation; glycan profiling; glycoengineering; host– pathogen interactions; therapeutic glycoproteins; bioorthogonal chemistry
Molecular Mechanisms of Autophagy, Apoptosis and Senescence and Therapeutic Advances in Cancer Progression submission deadline 30 Apr 2026 | Viewed by 53 | Submission Open
Keywords: cancer progression; cell death; senescence; cancer therapy
Telomere Maintenance and Metabolic Reprogramming in the Tumor Microenvironment
edited by and Jiyue Zhu
submission deadline 30 Apr 2026 | Viewed by 47 | Submission Open
Keywords: telomere maintenance mechanisms (TMM); tumor microenvironment (TME); telomerase activation; alternative lengthening of telomeres (ALT); cancer metabolism; mitochondrial dysfunction; redox homeostasis; DNA damage response (DDR); epigenetic regulation; cancer therapeutics; senescence-associated secretory phenotypes (SASPs)
(This special issue belongs to the Section Cell Microenvironment)
Advances in Neuropathology: Cellular, Molecular and Precision Mechanisms in Neurodegenerative Diseases submission deadline 30 Apr 2026 | Viewed by 38 | Submission Open
Keywords: neurodegeneration; Alzheimer's disease; Parkinson's disease; glial cells; synaptic dysfunction; protein aggregation; lysosomal function; autophagy; precision medicine
New Therapeutic Approaches to Cardiac Repair
edited by Dinakar Iyer
submission deadline 30 Apr 2026 | Viewed by 36 | Submission Open
Keywords: cardiac regeneration; CRISPR/base editing; mRNA therapeutics; circular RNA (circRNA); lipid nanoparticles (LNPs); engineered exosomes/extracellular vesicles; direct cardiac reprogramming; engineered heart muscle/3D cardiac patches; myocardial infarction repair; translational cardiology
Hematologic Diseases: From Cellular and Molecular Mechanisms to Therapies submission deadline 30 Apr 2026 | Viewed by 35 | Submission Open
Keywords: hematologic diseases; mechanisms; therapies
Molecular Signaling and Mechanism on Vascular Remodeling
edited by Ki Ho Park and Yitao Huang
submission deadline 30 Apr 2026 | Viewed by 31 | Submission Open
Keywords: vascular diseases; atherosclerosis; aneurysm; intimal hyperplasia; vascular remodeling; cellular mechanisms; cellular signaling
Post-Transcriptional Control of Stem Cell Fate and Neural Development
edited by
submission deadline 30 Apr 2026 | Viewed by 29 | Submission Open
Keywords: post-transcriptional regulation; stem cell biology; neural development; developmental biology
(This special issue belongs to the Section Stem Cells)
Kidney Development: Cellular and Molecular Insights submission deadline 30 Apr 2026 | Viewed by 26 | Submission Open
Keywords: kidney development; nephrogenesis; single-cell RNA-seq/ATAC-seq; congenital anomalies of the kidney and urinary tract (CAKUT); blood pressure regulation
Noncoding RNAs: Immunity, Mechanisms, and Biomarker Potential
edited by
submission deadline 30 Apr 2026 | Viewed by 18 | Submission Open
Keywords: noncoding RNAs (ncRNAs); MicroRNAs (miRNAs); long noncoding RNAs (lncRNAs); circular RNAs (circRNAs); immune regulation; tumor microenvironment; immune checkpoints; cancer immunotherapy; liquid biopsy biomarkers; immune evasion
Back to TopTop