Special Issue "Ubiquitin and Autophagy"
Deadline for manuscript submissions: closed (31 October 2020) | Viewed by 27791
This Special Issue of Cells on “Ubiquitin and Autophagy” is a tribute to the multifaceted role of ubiquitin and ubiquitin-like proteins in autophagy-related pathways. Ubiquitin is a small regulatory protein that is used to modify other proteins in the process called ubiquitination. The specificity of ubiquitination depends on ubiquitin ligases, the enzymes that place ubiquitin on specific substrates. They are counteracted by ubiquitin proteases in an opposite process of deubiquitination. As a result of ubiquitination of a substrate and ubiquitination of ubiquitin itself on this substrate, proteins might become polyubiquitinated with various ubiquitin chains and degraded via either the ubiquitin-proteasome system or autophagy-lysosome pathway. Moreover, the polyubiquitination of proteins in protein aggregates, at the surface of organelles and intracellular pathogens often leads to sequestration of these structures from the cytosol by autophagosomes and their delivery to the lysosomes for degradation and recycling. We are particularly interested in research articles and reviews at the intersection of ubiquitin-related processes and autophagy, including the roles of ubiquitin ligases and proteases in autophagy; ubiquitination and deubiquitination of autophagic substrates and players; ubiquitin-binding autophagic adaptors and their roles in selective autophagy; ubiquitin-like autophagic proteins and their conjugation systems; etc. In addition, papers on the crosstalk between the ubiquitin-proteasome system and autophagy-lysosome pathway are welcomed. We look forward to your contributions to this exciting Special Issue!
Dr. Taras Y. Nazarko
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Ubiquitin and ubiquitin-like proteins
- Ubiquitin ligases and proteases
- Ubiquitination and deubiquitination
- Polyubiquitination and ubiquitin chains
- Ubiquitin-binding adaptor proteins
- Ubiquitin-proteasome system
- Autophagy-lysosome pathway
- Non-selective and selective autophagy