Cellular Differentiation in Health and Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 25 December 2025 | Viewed by 455
Special Issue Editors
Interests: human anatomical pathology; gynae pathology; perinatal pathology
Special Issue Information
Dear Colleagues,
Cell differentiation is a key factor influencing many biological processes in health and disease. Understanding the mechanisms governing cell differentiation can provide opportunities for the manipulation of various disease processes, potentially leading to the basis for cures of currently intractable conditions and regenerative therapies. Many factors can influence cell differentiation, such as microenvironment, signaling pathways, cell to cell interactions and endocrine factors, which often interact. Cell differentiation occurs as a normal physiological process during development and some aspects of regeneration/healing, but also in pathological processes; for example, tumour cells can differentiate to show different morphological and growth characteristics. Comparison and contrast of the different physiological and pathological processes might provide useful clues, for example, cell signaling pathways in development and disease have some similarities. This Special Issue aims to explore drivers and mechanisms of cell differentiation in normal and pathological conditions, especially with regard to human health and disease. In vitro and in vivo observations can be compared and possible therapeutic manipulations can be explored. This Special Issue is complex and input from different fields is often helpful. Contributions from investigators of different backgrounds and areas of expertise are encouraged.
Dr. Christine K. C. Loo
Prof. Dr. Grant A. Ramm
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cellular differentiation
- tumour microenvironment
- human development
- regeneration/healing
- cell signaling pathways
- tumour differentiation
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